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Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling.
- Published in:
- Cells (2073-4409), 2018, v. 7, n. 11, p. 217, doi. 10.3390/cells7110217
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- Article
Mechanisms of glabridin inhibition of integrin α<sub>IIb</sub>β<sub>3</sub> inside-out signals and NF-κB activation in human platelets.
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- Chinese Medicine, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13020-023-00779-9
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- Article
Morin hydrate suppresses lipoteichoic acid-induced oxidative stress-mediated inflammatory events in macrophages via augmenting Nrf2/HO-1 and antioxidant defense molecules.
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- European Journal of Inflammation, 2023, p. 1, doi. 10.1177/1721727X231199414
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- Article
Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells.
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- Molecules, 2022, v. 27, n. 16, p. 5143, doi. 10.3390/molecules27165143
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- Article
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB.
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- Molecules, 2022, v. 27, n. 2, p. 476, doi. 10.3390/molecules27020476
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- Article
Structure-Antiplatelet Activity Relationships of Novel Ruthenium (II) Complexes: Investigation of Its Molecular Targets.
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- Molecules, 2018, v. 23, n. 2, p. 477, doi. 10.3390/molecules23020477
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- Article
Eugenol Suppresses Platelet Activation and Mitigates Pulmonary Thromboembolism in Humans and Murine Models.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 4, p. 2098, doi. 10.3390/ijms25042098
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- Article
Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11372, doi. 10.3390/ijms231911372
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- Article
Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5889, doi. 10.3390/ijms23115889
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- Article
Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 92, doi. 10.3390/ijms23010092
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- Article
The Antithrombotic Agent Pterostilbene Interferes with Integrin α IIb β 3 -Mediated Inside-Out and Outside-In Signals in Human Platelets.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3643, doi. 10.3390/ijms22073643
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- Article
Regulation of Human Platelet Activation and Prevention of Arterial Thrombosis in Mice by Auraptene through Inhibition of NF-κB Pathway.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 13, p. 4810, doi. 10.3390/ijms21134810
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- Article
Suppression of Human Platelet Activation via Integrin αIIbβ3 Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 22, p. 5585, doi. 10.3390/ijms20225585
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- Article
Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2–PKC–AKT Activation in Human Platelets.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 11, p. 2731, doi. 10.3390/ijms20112731
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- Article
Structure–Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3641, doi. 10.3390/ijms19113641
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- Article
Novel Therapeutic Agent against Platelet Activation In Vitro and Arterial Thrombosis In Vivo by Morin Hydrate.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 8, p. 2386, doi. 10.3390/ijms19082386
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- Article
Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1818, doi. 10.3390/ijms19061818
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- Article
Comparison of the Potency of Pterostilbene with NF-κB Inhibitors in Platelet Activation: Mutual Activation by Akt-NF-κB Signaling in Human Platelets.
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- Applied Sciences (2076-3417), 2021, v. 11, n. 13, p. 6149, doi. 10.3390/app11136149
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- Article
Involvement of Antioxidant Defenses and NF-κB/ERK Signaling in Anti-Inflammatory Effects of Pterostilbene, a Natural Analogue of Resveratrol.
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- Applied Sciences (2076-3417), 2021, v. 11, n. 10, p. 4666, doi. 10.3390/app11104666
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- Article
TQ-6, a Novel Ruthenium Derivative Compound, Possesses Potent Free Radical Scavenging Activity in Macrophages and Rats.
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- Applied Sciences (2076-3417), 2021, v. 11, n. 3, p. 1008, doi. 10.3390/app11031008
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- Publication type:
- Article
Reduction of NF-κB Signals in Platelets and Prolongation of Platelet Plug Formation against High Shear Flow in Whole Blood on Human Subject by Columbianadin.
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- Applied Sciences (2076-3417), 2020, v. 10, n. 20, p. 7323, doi. 10.3390/app10207323
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- Article
Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation.
- Published in:
- Bioinorganic Chemistry & Applications, 2018, p. 1, doi. 10.1155/2018/8291393
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- Article
Author Correction: A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice.
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- 2020
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- Correction Notice
Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation.
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- 2019
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- Publication type:
- Correction Notice
Ruthenium complex, TQ-5, protects against LPS-induced macrophage inflammation and acute liver injury in mice via downregulating NF-κB pathways.
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- International Journal of Molecular Medicine, 2019, v. 44, n. 1, p. 335, doi. 10.3892/ijmm.2019.419
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- Article
Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation.
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- International Journal of Molecular Medicine, 2018, v. 41, n. 5, p. 2589, doi. 10.3892/ijmm.2018.3472
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- Article
A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice.
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- Scientific Reports, 2017, p. 42277, doi. 10.1038/srep42277
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- Publication type:
- Article
Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin αIIbβ3 inside-out but not outside-in signals.
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- Journal of Biomedical Science, 2020, v. 27, n. 1, p. 1, doi. 10.1186/s12929-020-0619-5
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- Publication type:
- Article
Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways.
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- Evidence-based Complementary & Alternative Medicine (eCAM), 2021, p. 1, doi. 10.1155/2021/5319584
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- Article
Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation.
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- Journal of Clinical Medicine, 2020, v. 9, n. 4, p. 996, doi. 10.3390/jcm9040996
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- Article
Ginkgetin effectively mitigates collagen and AA‐induced platelet activation via PLCγ2 but not cyclic nucleotide‐dependent pathway in human.
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- Journal of Cellular & Molecular Medicine, 2024, v. 28, n. 4, p. 1, doi. 10.1111/jcmm.18139
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- Article
Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen–integrin α<sub>II</sub><sub>b</sub>β<sub>3</sub> binding in human platelets.
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- Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 4, p. 2142, doi. 10.1111/jcmm.13488
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- Article
Corrigendum to "Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways".
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- Evidence-based Complementary & Alternative Medicine (eCAM), 2022, p. 1, doi. 10.1155/2022/9805697
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- Publication type:
- Article
Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on ∙ OH Radicals and HO-1 Expression.
- Published in:
- Antioxidants, 2021, v. 10, n. 4, p. 553, doi. 10.3390/antiox10040553
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- Publication type:
- Article