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Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.
Published in:
2010
By:
- Grigorieva, Irina V.;
- Mirczuk, Samantha;
- Gaynor, Katherine U.;
- Nesbit, M. Andrew;
- Grigorieva, Elena F.;
- Qiaozhi Wei;
- Ali, Asif;
- Fairclough, Rebecca J.;
- Stacey, Joanna M.;
- Stechman, Michael J.;
- Mihai, Radu;
- Kurek, Dorota;
- Fraser, William D.;
- Hough, Tertius;
- Condie, Brian G.;
- Manley, Nancy;
- Grosveld, Frank;
- Thakker, Rajesh V.;
- Wei, Qiaozhi
Publication type:
journal article
A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.
Published in:
Journal of Bone & Mineral Research, 2012, v. 27, n. 2, p. 413, doi. 10.1002/jbmr.547
By:
- Esapa, Christopher T;
- Hough, Tertius A;
- Testori, Sarah;
- Head, Rosie A;
- Crane, Elizabeth A;
- Chan, Carol PS;
- Evans, Holly;
- Bassett, JH Duncan;
- Tylzanowski, Przemko;
- McNally, Eugene G;
- Carr, Andrew J;
- Boyde, Alan;
- Howell, Peter GT;
- Clark, Anne;
- Williams, Graham R;
- Brown, Matthew A;
- Croucher, Peter I;
- Nesbit, M Andrew;
- Brown, Steve DM;
- Cox, Roger D
Publication type:
Article
Novel Mouse Model of Autosomal Semidominant Adult Hypophosphatasia Has a Splice Site Mutation in the Tissue Nonspecific Alkaline Phosphatase Gene Akp2.
Published in:
Journal of Bone & Mineral Research, 2007, v. 22, n. 9, p. 1397, doi. 10.1359/JBMR.070515
By:
- Hough, Tertius A.;
- Polewski, Monika;
- Johnson, Kristen;
- Cheeseman, Michael;
- Nolan, Patrick M.;
- Vizor, Lucie;
- Rastan, Sohaila;
- Boyde, Alan;
- Pritzker, Kenneth;
- Hunter, A. Jackie;
- Fisher, Elizabeth M.C.;
- Terkeltaub, Robert;
- Brown, Steve D.M.
Publication type:
Article
Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome.
Published in:
Journal of Pathology, 2014, v. 233, n. 1, p. 18, doi. 10.1002/path.4308
By:
- Bull, Katherine R;
- Mason, Thomas;
- Rimmer, Andrew J;
- Crockford, Tanya L;
- Silver, Karlee L;
- Bouriez‐Jones, Tiphaine;
- Hough, Tertius A;
- Chaudhry, Shirine;
- Roberts, Ian SD;
- Goodnow, Christopher C;
- Cornall, Richard J
Publication type:
Article
A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas.
Published in:
Nature Genetics, 2004, v. 36, n. 8, p. 894, doi. 10.1038/ng1398
By:
- Williamson, Christine M.;
- Ball, Simon T.;
- Nottingham, Wade T.;
- Skinner, Judith A.;
- Plagge, Antonius;
- Turner, Martin D.;
- Powles, Nicola;
- Hough, Tertius;
- Papworth, David;
- Fraser, William D.;
- Maconochie, Mark;
- Peters, Jo
Publication type:
Article
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Published in:
Nature Genetics, 2000, v. 25, n. 4, p. 440, doi. 10.1038/78140
By:
- Nolan, Patrick M.;
- Peters, Jo;
- Strivens, Mark;
- Rogers, Derek;
- Hagan, Jim;
- Spurr, Nigel;
- Gray, Ian C.;
- Vizor, Lucie;
- Brooker, Debra;
- Whitehill, Elaine;
- Washbourne, Rebecca;
- Hough, Tertius;
- Greenaway, Simon;
- Hewitt, Mazda;
- Liu, Xinhong;
- McCormack, Stefan;
- Pickford, Karen;
- Selley, Rachael;
- Wells, Christine
Publication type:
Article
Pharmacological Inhibition of FTO.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0121829
By:
- McMurray, Fiona;
- Demetriades, Marina;
- Aik, WeiShen;
- Merkestein, Myrte;
- Kramer, Holger;
- Andrew, Daniel S.;
- Scudamore, Cheryl L.;
- Hough, Tertius A.;
- Wells, Sara;
- Ashcroft, Frances M.;
- McDonough, Michael A.;
- Schofield, Christopher J.;
- Cox, Roger D.
Publication type:
Article
Gene Dosage Effects at the Imprinted <i>Gnas</i> Cluster.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065639
By:
- Ball, Simon T.;
- Kelly, Michelle L.;
- Robson, Joan E.;
- Turner, Martin D.;
- Harrison, Jackie;
- Jones, Lynn;
- Napper, Diane;
- Beechey, Colin V.;
- Hough, Tertius;
- Plagge, Antonius;
- Cattanach, Bruce M.;
- Cox, Roger D.;
- Peters, Jo
Publication type:
Article
Autosomal Dominant Hypercalciuria in a Mouse Model Due to a Mutation of the Epithelial Calcium Channel, TRPV5.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055412
By:
- Loh, Nellie Y.;
- Bentley, Liz;
- Dimke, Henrik;
- Verkaart, Sjoerd;
- Tammaro, Paolo;
- Gorvin, Caroline M.;
- Stechman, Michael J.;
- Ahmad, Bushra N.;
- Hannan, Fadil M.;
- Piret, Sian E.;
- Evans, Holly;
- Bellantuono, Ilaria;
- Hough, Tertius A.;
- Fraser, William D.;
- Hoenderop, Joost G. J.;
- Ashcroft, Frances M.;
- Brown, Steve D. M.;
- Bindels, René J. M.;
- Cox, Roger D.;
- Thakker, Rajesh V.
Publication type:
Article
A Mouse Model for Osseous Heteroplasia.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051835
By:
- Cheeseman, Michael T.;
- Vowell, Kate;
- Hough, Tertius A.;
- Jones, Lynn;
- Pathak, Paras;
- Tyrer, Hayley E.;
- Kelly, Michelle;
- Cox, Roger;
- Warren, Madhuri V.;
- Peters, Jo
Publication type:
Article
A Mouse with an N-Ethyl- N-Nitrosourea (ENU) Induced Trp589Arg Galnt3Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043205
By:
- Esapa, Christopher T.;
- Head, Rosie A.;
- Jeyabalan, Jeshmi;
- Evans, Holly;
- Hough, Tertius A.;
- Cheeseman, Michael T.;
- McNally, Eugene G.;
- Carr, Andrew J.;
- Thomas, Gethin P.;
- Brown, Matthew A.;
- Croucher, Peter I.;
- Brown, Steve D. M.;
- Cox, Roger D.;
- Thakker, Rajesh V.;
- Aprikyan, Andranik Andrew
Publication type:
Article
Chronically elevated branched chain amino acid levels are pro-arrhythmic.
Published in:
Cardiovascular Research, 2022, v. 118, n. 7, p. 1742, doi. 10.1093/cvr/cvab207
By:
- Portero, Vincent;
- Nicol, Thomas;
- Podliesna, Svitlana;
- Marchal, Gerard A;
- Baartscheer, Antonius;
- Casini, Simona;
- Tadros, Rafik;
- Treur, Jorien L;
- Tanck, Michael W T;
- Cox, I Jane;
- Probert, Fay;
- Hough, Tertius A;
- Falcone, Sara;
- Beekman, Leander;
- Müller-Nurasyid, Martina;
- Kastenmüller, Gabi;
- Gieger, Christian;
- Peters, Annette;
- Kääb, Stefan;
- Sinner, Moritz F
Publication type:
Article
Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.
Published in:
FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202201918R
By:
- Bai, Ying;
- Bentley, Liz;
- Ma, Chao;
- Naveenan, Navaratnam;
- Cleak, James;
- Wu, Yixing;
- Simon, Michelle M.;
- Westerberg, Henrik;
- Cañas, Ramón Casero;
- Horner, Neil;
- Pandey, Rajesh;
- Paphiti, Keanu;
- Schulze, Ulrike;
- Mianné, Joffrey;
- Hough, Tertius;
- Teboul, Lydia;
- de Baaij, Jeroen H. F.;
- Cox, Roger D.
Publication type:
Article
Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0163214
By:
- Elshorbagy, Amany K.;
- Jernerén, Fredrik;
- Scudamore, Cheryl L.;
- McMurray, Fiona;
- Cater, Heather;
- Hough, Tertius;
- Cox, Roger;
- Refsum, Helga
Publication type:
Article
A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.
Published in:
2004
By:
- Toye, Ayo A.;
- Moir, Lee;
- Hugill, Alison;
- Bentley, Liz;
- Quarterman, Julie;
- Mijat, Vesna;
- Hough, Tertius;
- Goldsworthy, Michelle;
- Haynes, Alison;
- Hunter, A. Jacqueline;
- Browne, Mick;
- Spurr, Nigel;
- Cox, Roger D.
Publication type:
journal article
Maternal inheritance of the Gnas cluster mutation Ex1A- T affects size, implicating NESP55 in growth.
Published in:
Mammalian Genome, 2013, v. 24, n. 7/8, p. 276, doi. 10.1007/s00335-013-9462-2
By:
- Eaton, Sally;
- Hough, Tertius;
- Fischer-Colbrie, Reiner;
- Peters, Jo
Publication type:
Article
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.
Published in:
Mammalian Genome, 2009, v. 20, n. 3, p. 140, doi. 10.1007/s00335-008-9169-y
By:
- Pastorelli, Laura M.;
- Wells, Sara;
- Fray, Martin;
- Smith, Adrian;
- Hough, Tertius;
- Harfe, Brian D.;
- McManus, Michael T.;
- Smith, Lee;
- Woolf, Adrian S.;
- Cheeseman, Michael;
- Greenfield, Andy
Publication type:
Article
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
Published in:
Mammalian Genome, 2006, v. 17, n. 2, p. 129, doi. 10.1007/s00335-005-0112-1
By:
- Solberg, Leah C.;
- Valdar, William;
- Gauguier, Dominique;
- Nunez, Graciela;
- Taylor, Amy;
- Burnett, Stephanie;
- Arboledas-Hita, Carmen;
- Hernandez-Pliego, Polinka;
- Davidson, Stuart;
- Burns, Peter;
- Bhattacharya, Shoumo;
- Hough, Tertius;
- Higgs, Douglas;
- Klenerman, Paul;
- Cookson, William O.;
- Zhang, Youming;
- Deacon, Robert M.;
- Rawlins, J. Nicholas P.;
- Mott, Richard;
- Flint, Jonathan
Publication type:
Article
Novel phenotypes identified by plasma biochemical screening in the mouse.
Published in:
Mammalian Genome, 2002, v. 13, n. 10, p. 595, doi. 10.1007/s00335-002-2188-1
By:
- Hough, Tertius A.;
- Nolan, Patrick M.;
- Tsipouri, Vicky;
- Toye, Ayo A.;
- Gray, Ian C.;
- Goldsworthy, Michelle;
- Moir, Lee;
- Cox, Roger D.;
- Clements, Sian;
- Glenister, Peter H.;
- Wood, John;
- Selley, Rachael L.;
- Strivens, Mark A.;
- Vizor, Lucie;
- McCormack, Stefan L.;
- Peters, Josephine;
- Fisher, Elizabeth M.;
- Spurr, Nigel;
- Rastan, Sohaila;
- Martin, Joanne E.
Publication type:
Article
Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.
Published in:
Mammalian Genome, 2000, v. 11, n. 7, p. 500, doi. 10.1007/s003350010096
By:
- Nolan, Patrick M.;
- Peters, Jo;
- Vizor, Lucie;
- Strivens, Mark;
- Washbourne, Rebecca;
- Hough, Tertius;
- Wells, Christine;
- Glenister, Peter;
- Thornton, Claire;
- Martin, Jo;
- Fisher, Elizabeth;
- Rogers, Derek;
- Hagan, Jim;
- Reavill, Charlie;
- Gray, Ian;
- Wood, John;
- Spurr, Nigel;
- Browne, Mick;
- Rastan, Sohaila;
- Hunter, Jackie
Publication type:
Article
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-01995-2
By:
- Rozman, Jan;
- Rathkolb, Birgit;
- Oestereicher, Manuela A.;
- Schütt, Christine;
- Ravindranath, Aakash Chavan;
- Leuchtenberger, Stefanie;
- Sharma, Sapna;
- Kistler, Martin;
- Willershäuser, Monja;
- Brommage, Robert;
- Meehan, Terrence F.;
- Mason, Jeremy;
- Haselimashhadi, Hamed;
- Hough, Tertius;
- Mallon, Ann-Marie;
- Wells, Sara;
- Santos, Luis;
- Lelliott, Christopher J.;
- White, Jacqueline K.;
- Sorg, Tania
Publication type:
Article
HIF--VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants.
Published in:
PLoS Genetics, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.pgen.1002336
By:
- Cheeseman, Michael T.;
- Tyrer, Hayley E.;
- Williams, Debbie;
- Hough, Tertius A.;
- Pathak, Paras;
- Romero, Maria R.;
- Hilton, Helen;
- Bali, Sulzhan;
- Parker, Andrew;
- Vizor, Lucie;
- Purnell, Tom;
- Vowell, Kate;
- Wells, Sara;
- Bhutta, Mahmood F.;
- Potter, Paul K.;
- Brown, Steve D. M.
Publication type:
Article
A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy.
Published in:
PLoS Genetics, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pgen.1001000
By:
- Ashrafian, Houman;
- Docherty, Louise;
- Leo, Vincenzo;
- Towlson, Christopher;
- Neilan, Monica;
- Steeples, Violetta;
- Lygate, Craig A.;
- Hough, Tertius;
- Townsend, Stuart;
- Williams, Debbie;
- Wells, Sara;
- Norris, Dominic;
- Glyn-Jones, Sarah;
- Land, John;
- Barbaric, Ivana;
- Lalanne, Zuzanne;
- Denny, Paul;
- Szumska, Dorota;
- Bhattacharya, Shoumo;
- Griffin, Julian L.
Publication type:
Article
Mutation at the Evi1 Locus in Junbo Mice Causes Susceptibility to Otitis Media.
Published in:
PLoS Genetics, 2006, v. 3, n. 4, p. 1556, doi. 10.1371/journal.pgen.0020149
By:
- Parkinson, Nicholas;
- Hardisty-Hughes, Rachel E.;
- Tateossian, Hilda;
- Hsun-Tien Tsai;
- Brooker, Debra;
- Morse, Sue;
- Lalane, Zuzanna;
- MacKenzie, Francesca;
- Fray, Martin;
- Glenister, Pete;
- Woodward, Anne-Marie;
- Polley, Sian;
- Barbaric, Ivana;
- Dear, Neil;
- Hough, Tertius A.;
- Hunter, A. Jackie;
- Cheeseman, Michael T.;
- Brown, Steve D. M.
Publication type:
Article
Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 19, p. 3553, doi. 10.1093/hmg/ddp304
By:
- Mackenzie, Francesca E.;
- Romero, Rosario;
- Williams, Debbie;
- Gillingwater, Thomas;
- Hilton, Helen;
- Dick, Jim;
- Riddoch-Contreras, Joanna;
- Wong, Frances;
- Ireson, Lisa;
- Powles-Glover, Nicola;
- Riley, Genna;
- Underhill, Peter;
- Hough, Tertius;
- Arkell, Ruth;
- Greensmith, Linda;
- Ribchester, Richard R.;
- Blanco, Gonzalo
Publication type:
Article
Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis.
Published in:
Journal of Bone & Mineral Research, 2019, v. 34, n. 7, p. 1324, doi. 10.1002/jbmr.3695
By:
- Gorvin, Caroline M;
- Loh, Nellie Y;
- Stechman, Michael J;
- Falcone, Sara;
- Hannan, Fadil M;
- Ahmad, Bushra N;
- Piret, Sian E;
- Reed, Anita AC;
- Jeyabalan, Jeshmi;
- Leo, Paul;
- Marshall, Mhairi;
- Sethi, Siddharth;
- Bass, Paul;
- Roberts, Ian;
- Sanderson, Jeremy;
- Wells, Sara;
- Hough, Tertius A;
- Bentley, Liz;
- Christie, Paul T;
- Simon, Michelle M
Publication type:
Article
An N‐Ethyl‐N‐Nitrosourea (ENU)‐Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
Published in:
Journal of Bone & Mineral Research, 2019, v. 34, n. 3, p. 497, doi. 10.1002/jbmr.3624
By:
- Gorvin, Caroline M;
- Ahmad, Bushra N;
- Stechman, Michael J;
- Loh, Nellie Y;
- Hough, Tertius A;
- Leo, Paul;
- Marshall, Mhairi;
- Sethi, Siddharth;
- Bentley, Liz;
- Piret, Sian E;
- Reed, Anita;
- Jeyabalan, Jeshmi;
- Christie, Paul T;
- Wells, Sara;
- Simon, Michelle M;
- Mallon, Ann‐Marie;
- Schulz, Herbert;
- Huebner, Norbert;
- Brown, Matthew A;
- Cox, Roger D
Publication type:
Article
Establishing normal plasma and 24-hour urinary biochemistry ranges in C3H, BALB/c and C57BL/6J mice following acclimatization in metabolic cages.
Published in:
Laboratory Animals, 2010, v. 44, n. 3, p. 218, doi. 10.1258/la.2010.009128
By:
- Stechman, Michael J.;
- Ahmad, Bushra N.;
- Loh, Nellie Y.;
- Reed, Anita A. C.;
- Stewart, Michelle;
- Wells, Sara;
- Hough, Tertius;
- Bentley, Liz;
- Cox, Roger D.;
- Brown, Steve D. M.;
- Thakker, Rajesh V.
Publication type:
Article
A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall‐Smith Syndrome.
Published in:
JBMR Plus, 2023, v. 7, n. 6, p. 1, doi. 10.1002/jbm4.10739
By:
- Kooblall, Kreepa G.;
- Stevenson, Mark;
- Stewart, Michelle;
- Harris, Lachlan;
- Zalucki, Oressia;
- Dewhurst, Hannah;
- Butterfield, Natalie;
- Leng, Houfu;
- Hough, Tertius A.;
- Ma, Da;
- Siow, Bernard;
- Potter, Paul;
- Cox, Roger D.;
- Brown, Stephen D.M.;
- Horwood, Nicole;
- Wright, Benjamin;
- Lockstone, Helen;
- Buck, David;
- Vincent, Tonia L.;
- Hannan, Fadil M.
Publication type:
Article
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
Published in:
PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006033
By:
- Peiris, Heshan;
- Duffield, Michael D.;
- Fadista, Joao;
- Jessup, Claire F.;
- Kashmir, Vinder;
- Genders, Amanda J.;
- McGee, Sean L.;
- Martin, Alyce M.;
- Saiedi, Madiha;
- Morton, Nicholas;
- Carter, Roderick;
- Cousin, Michael A.;
- Kokotos, Alexandros C.;
- Oskolkov, Nikolay;
- Volkov, Petr;
- Hough, Tertius A.;
- Fisher, Elizabeth M. C.;
- Tybulewicz, Victor L. J.;
- Busciglio, Jorge;
- Coskun, Pinar E.
Publication type:
Article

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