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Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.
Published in:
2020
By:
- Georgakis, Marios K;
- Malik, Rainer;
- Anderson, Christopher D;
- Parhofer, Klaus G;
- Hopewell, Jemma C;
- Dichgans, Martin
Publication type:
journal article
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
Published in:
Nature Genetics, 2011, v. 43, n. 4, p. 339, doi. 10.1038/ng.782
By:
- Peden, John F;
- Hopewell, Jemma C;
- Saleheen, Danish;
- Chambers, John C;
- Hager, Jorg;
- Soranzo, Nicole;
- Collins, Rory;
- Danesh, John;
- Elliott, Paul;
- Farrall, Martin;
- Stirrups, Kathy;
- Zhang, Weihua;
- Hamsten, Anders;
- Parish, Sarah;
- Lathrop, Mark;
- Watkins, Hugh;
- Clarke, Robert;
- Deloukas, Panos;
- Kooner, Jaspal S;
- Goel, Anuj
Publication type:
Article
Identifying systematic heterogeneity patterns in genetic association meta-analysis studies.
Published in:
PLoS Genetics, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.pgen.1006755
By:
- Magosi, Lerato E.;
- Goel, Anuj;
- Hopewell, Jemma C.;
- Farrall, Martin;
- null, null
Publication type:
Article
The Use of Primary Care Big Data in Understanding the Pharmacoepidemiology of COVID-19: A Consensus Statement From the COVID-19 Primary Care Database Consortium.
Published in:
2021
By:
- Dambha-Miller, Hajira;
- Griffin, Simon J.;
- Young, Duncan;
- Watkinson, Peter;
- Pui San Tan;
- Clift, Ashley K.;
- Payne, Rupert A.;
- Coupland, Carol;
- Hopewell, Jemma C.;
- Mant, Jonathan;
- Martin, Richard M.;
- Hippisley-Cox, Julia;
- Tan, Pui San
Publication type:
journal article
No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.
Published in:
Scientific Reports, 2016, p. 35278, doi. 10.1038/srep35278
By:
- Loley, Christina;
- Alver, Maris;
- Assimes, Themistocles L.;
- Bjonnes, Andrew;
- Goel, Anuj;
- Gustafsson, Stefan;
- Hernesniemi, Jussi;
- Hopewell, Jemma C.;
- Kanoni, Stavroula;
- Kleber, Marcus E.;
- Lau, King Wai;
- Lu, Yingchang;
- Lyytikäinen, Leo-Pekka;
- Nelson, Christopher P.;
- Nikpay, Majid;
- Qu, Liming;
- Salfati, Elias;
- Scholz, Markus;
- Tukiainen, Taru;
- Willenborg, Christina
Publication type:
Article
Independent risk factors for simvastatin-related myopathy and relevance to different types of muscle symptom.
Published in:
European Heart Journal, 2020, v. 41, n. 35, p. 3336, doi. 10.1093/eurheartj/ehaa574
By:
- Hopewell, Jemma C;
- Offer, Alison;
- Haynes, Richard;
- Bowman, Louise;
- Li, Jing;
- Chen, Fang;
- Bulbulia, Richard;
- Lathrop, Mark;
- Baigent, Colin;
- Landray, Martin J;
- Collins, Rory;
- Armitage, Jane;
- Parish, Sarah
Publication type:
Article
Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease.
Published in:
JAMA: Journal of the American Medical Association, 2009, v. 302, n. 1, p. 37, doi. 10.1001/jama.2009.954
By:
- Elliott, Paul;
- Chambers, John C.;
- Weihua Zhang;
- Clarke, Robert;
- Hopewell, Jemma C.;
- Peden, John F.;
- Erdmann, Jeanette;
- Braund, Peter;
- Engert, James C.;
- Bennett, Derrick;
- Coin, Lachlan;
- Ashby, Deborah;
- Tzoulaki, Ioanna;
- Brown, Ian J.;
- Mt-Isa, Shahrul;
- McCarthy, Mark I.;
- Peltonen, Leena;
- Freimer, Nelson B.;
- Farrall, Martin;
- Ruokonen, Aimo
Publication type:
Article
Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries.
Published in:
PLoS Medicine, 2022, v. 19, n. 4, p. 1, doi. 10.1371/journal.pmed.1003967
By:
- Linden, Andrew B.;
- Clarke, Robert;
- Hammami, Imen;
- Hopewell, Jemma C.;
- Guo, Yu;
- Whiteley, William N.;
- Lin, Kuang;
- Turnbull, Iain;
- Chen, Yiping;
- Yu, Canqing;
- Lv, Jun;
- Offer, Alison;
- Bennett, Derrick;
- Walters, Robin G.;
- Li, Liming;
- Chen, Zhengming;
- Parish, Sarah
Publication type:
Article
Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries.
Published in:
2022
By:
- Linden, Andrew B;
- Clarke, Robert;
- Hammami, Imen;
- Hopewell, Jemma C;
- Guo, Yu;
- Whiteley, William N;
- Lin, Kuang;
- Turnbull, Iain;
- Chen, Yiping;
- Yu, Canqing;
- Lv, Jun;
- Offer, Alison;
- Bennett, Derrick;
- Walters, Robin G;
- Li, Liming;
- Chen, Zhengming;
- Parish, Sarah;
- China Kadoorie Biobank Collaborative Group
Publication type:
journal article
Assessment of the causal relevance of ECG parameters for risk of atrial fibrillation: A mendelian randomisation study.
Published in:
2021
By:
- Gajendragadkar, Parag Ravindra;
- Von Ende, Adam;
- Ibrahim, Maysson;
- Valdes-Marquez, Elsa;
- Camm, Christian Fielder;
- Murgia, Federico;
- Stiby, Alexander;
- Casadei, Barbara;
- Hopewell, Jemma C.
Publication type:
journal article
Assessement of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials.
Published in:
JAMA Network Open, 2019, v. 2, n. 3, p. e190223, doi. 10.1001/jamanetworkopen.2019.0223
By:
- Offer, Alison;
- Arnold, Matthew;
- Clarke, Robert;
- Bennett, Derrick;
- Bowman, Louise;
- Bulbulia, Richard;
- Haynes, Richard;
- Li, Jing;
- Hopewell, Jemma C.;
- Landray, Martin;
- Armitage, Jane;
- Collins, Rory;
- Parish, Sarah
Publication type:
Article
Proteomic profiling identifies novel independent relationships between inflammatory proteins and myocardial infarction.
Published in:
European Journal of Preventive Cardiology, 2023, v. 30, n. 7, p. 583, doi. 10.1093/eurjpc/zwad020
By:
- Valdes-Marquez, Elsa;
- Clarke, Robert;
- Hill, Michael;
- Watkins, Hugh;
- Hopewell, Jemma C
Publication type:
Article
Are polygenic risk scores for systolic blood pressure and LDL-cholesterol associated with treatment effectiveness, and clinical outcomes among those on treatment?
Published in:
European Journal of Preventive Cardiology, 2022, v. 29, n. 6, p. 925, doi. 10.1093/eurjpc/zwab192
By:
- Tapela, Neo M;
- Collister, Jennifer;
- Liu, Xiaonan;
- Clifton, Lei;
- Stiby, Alexander;
- Murgia, Federico;
- Hopewell, Jemma C;
- Hunter, David J
Publication type:
Article
Cardiovascular care of patients with stroke and high risk of stroke: The need for interdisciplinary action: A consensus report from the European Society of Cardiology Cardiovascular Round Table.
Published in:
European Journal of Preventive Cardiology, 2020, v. 27, n. 7, p. 682, doi. 10.1177/2047487319873460
By:
- Doehner, Wolfram;
- Mazighi, Mikael;
- Hofmann, Bernd M;
- Lautsch, Dominik;
- Hindricks, Gerhard;
- Bohula, Erin A;
- Byrne, Robert A;
- Camm, A John;
- Casadei, Barbara;
- Caso, Valeria;
- Cognard, Christophe;
- Diener, Hans-Christoph;
- Endres, Matthias;
- Goldstein, Patrick;
- Halliday, Alison;
- Hopewell, Jemma C;
- Jovanovic, Dejana R;
- Kobayashi, Adam;
- Kostrubiec, Maciej;
- Krajina, Antonin
Publication type:
Article
impact of atrial fibrillation and stroke risk factors on left atrial blood flow characteristics.
Published in:
European Heart Journal - Cardiovascular Imaging, 2022, v. 23, n. 1, p. 115, doi. 10.1093/ehjci/jeab213
By:
- Spartera, Marco;
- Stracquadanio, Antonio;
- Pessoa-Amorim, Guilherme;
- Ende, Adam Von;
- Fletcher, Alison;
- Manley, Peter;
- Ferreira, Vanessa M;
- Hess, Aaron T;
- Hopewell, Jemma C;
- Neubauer, Stefan;
- Wijesurendra, Rohan S;
- Casadei, Barbara
Publication type:
Article
Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke.
Published in:
Annals of Neurology, 2018, v. 84, n. 6, p. 934, doi. 10.1002/ana.25369
By:
- Malik, Rainer;
- Rannikmäe, Kristiina;
- Traylor, Matthew;
- Georgakis, Marios K.;
- Sargurupremraj, Muralidharan;
- Markus, Hugh S.;
- Hopewell, Jemma C.;
- Debette, Stephanie;
- Sudlow, Cathie L. M.;
- Dichgans, Martin
Publication type:
Article
Genome-wide meta-analysis identifies 3 novel loci associated with stroke.
Published in:
2018
By:
- Malik, Rainer;
- Rannikmäe, Kristiina;
- Traylor, Matthew;
- Georgakis, Marios K;
- Sargurupremraj, Muralidharan;
- Markus, Hugh S;
- Hopewell, Jemma C;
- Debette, Stephanie;
- Sudlow, Cathie L M;
- Dichgans, Martin;
- MEGASTROKE consortium and the International Stroke Genetics Consortium
Publication type:
journal article
Impact of New Cardiovascular Events on Quality of Life and Hospital Costs in People With Cardiovascular Disease in the United Kingdom and United States.
Published in:
Journal of the American Heart Association, 2023, v. 12, n. 19, p. 1, doi. 10.1161/JAHA.123.030766
By:
- Nga Man Lui, Juliana;
- Williams, Claire;
- Mi Jun Keng;
- Hopewell, Jemma C.;
- Sammons, Emily;
- Fang Chen;
- Gray, Alastair;
- Bowman, Louise;
- Landray, Sir Martin J.;
- Mihaylova, Borislava
Publication type:
Article
A key risk indicator approach to central statistical monitoring in multicentre clinical trials: method development in the context of an ongoing largescale randomized trial.
Published in:
2011
By:
- Elsa, Valdés-Márquez;
- Jemma, Hopewell C.;
- Martin, Landray;
- Jane, Armitage
Publication type:
Abstract
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Published in:
Nature, 2013, v. 502, n. 7471, p. 377, doi. 10.1038/nature12508
By:
- Mangravite, Lara M.;
- Engelhardt, Barbara E.;
- Medina, Marisa W.;
- Smith, Joshua D.;
- Brown, Christopher D.;
- Chasman, Daniel I.;
- Mecham, Brigham H.;
- Howie, Bryan;
- Shim, Heejung;
- Naidoo, Devesh;
- Feng, QiPing;
- Rieder, Mark J.;
- Chen, Yii.-Der I.;
- Rotter, Jerome I.;
- Ridker, Paul M.;
- Hopewell, Jemma C.;
- Parish, Sarah;
- Armitage, Jane;
- Collins, Rory;
- Wilke, Russell A.
Publication type:
Article
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis.
Published in:
PLoS Genetics, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.pgen.1000730
By:
- Chasman, Daniel I.;
- Paré, Guillaume;
- Mora, Samia;
- Hopewell, Jemma C.;
- Peloso, Gina;
- Clarke, Robert;
- Cupples, L. Adrienne;
- Hamsten, Anders;
- Kathiresan, Sekar;
- Mälarstig, Anders;
- Ordovas, José M.;
- Ripatti, Samuli;
- Parker, Alex N.;
- Miletich, Joseph P.;
- Ridker, Paul M.
Publication type:
Article
Independent relevance of adiposity measures to coronary heart disease risk among 0.5 million adults in UK Biobank.
Published in:
International Journal of Epidemiology, 2023, v. 52, n. 6, p. 1836, doi. 10.1093/ije/dyad143
By:
- Trichia, Eirini;
- Malden, Debbie E;
- Jin, Danyao;
- Wright, Neil;
- Taylor, Hannah;
- Karpe, Fredrik;
- Sherliker, Paul;
- Murgia, Federico;
- Hopewell, Jemma C;
- Lacey, Ben;
- Emberson, Jonathan;
- Bennett, Derrick;
- Lewington, Sarah
Publication type:
Article
Independent effects of adiposity measures on risk of atrial fibrillation in men and women: a study of 0.5 million individuals.
Published in:
2022
By:
- Camm, C Fielder;
- Lacey, Ben;
- Massa, M Sofia;
- Ende, Adam Von;
- Gajendragadkar, Parag;
- Stiby, Alexander;
- Valdes-Marquez, Elsa;
- Lewington, Sarah;
- Wijesurendra, Rohan;
- Parish, Sarah;
- Casadei, Barbara;
- Hopewell, Jemma C;
- Von Ende, Adam
Publication type:
journal article
Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke.
Published in:
European Heart Journal, 2018, v. 39, n. 5, p. 354, doi. 10.1093/eurheartj/ehx373
By:
- Hopewell, Jemma C;
- Malik, Rainer;
- Valdés-Márquez, Elsa;
- Worrall, Bradford B;
- Collins, Rory;
- ISGC, METASTROKE Collaboration of the
Publication type:
Article
Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.
Published in:
European Heart Journal, 2013, v. 34, n. 13, p. 982
By:
- Hopewell, Jemma C.;
- Parish, Sarah;
- Offer, Alison;
- Link, Emma;
- Clarke, Robert;
- Lathrop, Mark;
- Armitage, Jane;
- Collins, Rory
Publication type:
Article
Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias.
Published in:
PLoS Medicine, 2012, v. 9, n. 2, p. 1
By:
- Clarke, Robert;
- Bennett, Derrick A.;
- Parish, Sarah;
- Verhoef, Petra;
- Dötsch-Klerk, Mariska;
- Lathrop, Mark;
- Xu, Peng;
- Nordestgaard, Børge G.;
- Holm, Hilma;
- Hopewell, Jemma C.;
- Saleheen, Danish;
- Tanaka, Toshihiro;
- Anand, Sonia S.;
- Chambers, John C.;
- Kleber, Marcus E.;
- Ouwehand, Willem H.;
- Yamada, Yoshiji;
- Elbers, Clara;
- Peters, Bas;
- Stewart, Alexandre F. R.
Publication type:
Article
Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes.
Published in:
Genetic Epidemiology, 2022, v. 46, n. 1, p. 51, doi. 10.1002/gepi.22434
By:
- Grace, Christopher;
- Hopewell, Jemma C.;
- Watkins, Hugh;
- Farrall, Martin;
- Goel, Anuj
Publication type:
Article
Mendelian randomization with fine-mapped genetic data: Choosing from large numbers of correlated instrumental variables.
Published in:
Genetic Epidemiology, 2017, v. 41, n. 8, p. 714, doi. 10.1002/gepi.22077
By:
- Burgess, Stephen;
- Zuber, Verena;
- Valdes‐Marquez, Elsa;
- Sun, Benjamin B;
- Hopewell, Jemma C
Publication type:
Article
Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease.
Published in:
Bioinformatics, 2020, v. 36, n. 2, p. 552, doi. 10.1093/bioinformatics/btz590
By:
- Magosi, Lerato E;
- Goel, Anuj;
- Hopewell, Jemma C;
- Farrall, Martin
Publication type:
Article

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