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Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness.
- Published in:
- EMBO Molecular Medicine, 2021, v. 13, n. 2, p. 1, doi. 10.15252/emmm.202013259
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- Article
Split otoferlins reunited.
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- EMBO Molecular Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.15252/emmm.201809995
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- Publication type:
- Article
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
- Published in:
- 2011
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- Publication type:
- journal article
TMC function, dysfunction, and restoration in mouse vestibular organs.
- Published in:
- Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1356614
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- Publication type:
- Article
Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity.
- Published in:
- 2019
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- Publication type:
- Correction Notice
Continuous evolution of base editors with expanded target compatibility and improved activity.
- Published in:
- Nature Biotechnology, 2019, v. 37, n. 9, p. 1070, doi. 10.1038/s41587-019-0193-0
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- Article
Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells.
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- Nature Biotechnology, 2017, v. 35, n. 6, p. 583, doi. 10.1038/nbt.3840
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- Publication type:
- Article
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 3, p. 280, doi. 10.1038/nbt.3781
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- Publication type:
- Article
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 3, p. 264, doi. 10.1038/nbt.3801
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- Publication type:
- Article
Gene Transfer in Human Vestibular Epithelia and the Prospects for Inner Ear Gene Therapy.
- Published in:
- Laryngoscope, 2008, v. 118, n. 5, p. 821, doi. 10.1097/MLG.0b013e318164d0aa
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- Publication type:
- Article
Viral-mediated gene transfer to study the molecular physiology of the Mammalian inner ear.
- Published in:
- 2002
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- Publication type:
- journal article
Myosin-1 nomenclature.
- Published in:
- Journal of Cell Biology, 2001, v. 155, n. 5, p. 703, doi. 10.1083/jcb.200110032
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- Publication type:
- Article
HCN Channels Are Not Required for Mechanotransduction in Sensory Hair Cells of the Mouse Inner Ear.
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- PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008627
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- Article
Stimulus Processing by Type II Hair Cells in the Mouse Utricle.
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- Annals of the New York Academy of Sciences, 1999, v. 871, n. 1, p. 15, doi. 10.1111/j.1749-6632.1999.tb09172.x
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- Publication type:
- Article
Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.69433
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- Publication type:
- Article
Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/biom12070914
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- Publication type:
- Article
Efficient Viral Transduction in Fetal and Adult Human Inner Ear Explants with AAV9-PHP.B Vectors.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 816, doi. 10.3390/biom12060816
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- Publication type:
- Article
Publisher Correction: Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08264-w
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- Publication type:
- Article
Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08264-w
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- Publication type:
- Article
Development and Regeneration of Sensory Transduction in Auditory Hair Cells Requires Functional Interaction Between Cadherin-23 and Protocadherin-15.
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- Journal of Neuroscience, 2010, v. 30, n. 34, p. 11259, doi. 10.1523/JNEUROSCI.1949-10.2010
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- Publication type:
- Article
Dominant-Negative Inhibition of M-Like Potassium Conductances in Hair Cells of the Mouse Inner Ear.
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- Journal of Neuroscience, 2007, v. 27, n. 33, p. 8940, doi. 10.1523/JNEUROSCI.2085-07.2007
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- Publication type:
- Article
The Very Large G-Protein-Coupled Receptor VLGR1: A Component of the Ankle Link Complex Required for the Normal Development of Auditory Hair Bundles.
- Published in:
- 2006
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- Publication type:
- Abstract
Physical and Functional Interaction between Protocadherin 15 and Myosin VIIa in Mechanosensory Hair Cells.
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- Journal of Neuroscience, 2006, v. 26, n. 7, p. 2060, doi. 10.1523/JNEUROSCI.4251-05.2006
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- Publication type:
- Article
Developmental Acquisition of Voltage-Dependent Conductances and Sensory Signaling in Hair Cells of the Embryonic Mouse Inner Ear.
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- Journal of Neuroscience, 2004, v. 24, n. 49, p. 11148, doi. 10.1523/JNEUROSCI.2662-04.2004
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- Publication type:
- Article
Gene Therapy for Deaf Mice Goes Viral.
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- Molecular Therapy, 2012, v. 20, n. 10, p. 1836, doi. 10.1038/mt.2012.196
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- Publication type:
- Article
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.
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- Nature Communications, 2016, v. 7, n. 5, p. 11508, doi. 10.1038/ncomms11508
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- Publication type:
- Article
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness.
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- Science Translational Medicine, 2020, v. 12, n. 546, p. 1, doi. 10.1126/scitranslmed.aay9101
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- Publication type:
- Article
Tmc gene therapy restores auditory function in deaf mice.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 295, p. 1, doi. 10.1126/scitranslmed.aab1996
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- Publication type:
- Article
Putting the Pieces Together: the Hair Cell Transduction Complex.
- Published in:
- JARO - Journal of the Association for Research in Otolaryngology, 2021, v. 22, n. 6, p. 601, doi. 10.1007/s10162-021-00808-0
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- Publication type:
- Article
Emerging Gene Therapies for Genetic Hearing Loss.
- Published in:
- 2017
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- Publication type:
- journal article
A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.
- Published in:
- 2010
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- Publication type:
- journal article
Differential distribution of stem cells in the auditory and vestibular organs of the inner ear.
- Published in:
- 2007
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- Publication type:
- journal article
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.
- Published in:
- Nature, 2004, v. 432, n. 7018, p. 723, doi. 10.1038/nature03066
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- Publication type:
- Article
Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.
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- Human Molecular Genetics, 2014, v. 23, n. 9, p. 2374, doi. 10.1093/hmg/ddt629
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- Publication type:
- Article
Developmental acquisition of sensory transduction in hair cells of the mouse inner ear.
- Published in:
- Nature Neuroscience, 2003, v. 6, n. 10, p. 1019, doi. 10.1038/nn1120
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- Publication type:
- Article
Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?
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- Journal of Neuroscience, 2016, v. 36, n. 43, p. 10921, doi. 10.1523/JNEUROSCI.1148-16.2016
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- Publication type:
- Article
Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29709-8
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- Publication type:
- Article
Transgenic Tmc2 expression preserves inner ear hair cells and vestibular function in mice lacking Tmc1.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-28958-x
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- Publication type:
- Article
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.
- Published in:
- Science Translational Medicine, 2023, v. 15, n. 702, p. 1, doi. 10.1126/scitranslmed.abq3916
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- Publication type:
- Article
Genotype-Phenotype Correlations in TMPRSS3 (DFNB10/DFNB8) with Emphasis on Natural History.
- Published in:
- Audiology & Neurotology, 2023, v. 28, n. 6, p. 407, doi. 10.1159/000528766
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- Publication type:
- Article
The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 28, p. 9485, doi. 10.1523/JNEUROSCI.0311-12.2012
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- Publication type:
- Article
HCN Channels Expressed in the Inner Ear Are Necessary for Normal Balance Function.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 46, p. 16814, doi. 10.1523/JNEUROSCI.3064-11.2011
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- Publication type:
- Article
Polycystin-1 Is Required for Stereocilia Structure But Not for Mechanotransduction in Inner Ear Hair Cells.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 34, p. 12251, doi. 10.1523/JNEUROSCI.6531-10.2011
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- Publication type:
- Article