Found: 47

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  • Obesity Variants in the GIPR Gene Are not Associated With Risk of Fracture or Bone Mineral Density.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 8, p. e1608, doi. 10.1210/clinem/dgad734
    By:
    • Styrkarsdottir, Unnur;
    • Tragante, Vinicius;
    • Stefansdottir, Lilja;
    • Thorleifsson, Gudmar;
    • Oddsson, Asmundur;
    • Sørensen, Erik;
    • Erikstrup, Christian;
    • Schwarz, Peter;
    • Jørgensen, Henrik Løvendahl;
    • Lauritzen, Jes Bruun;
    • Brunak, Søren;
    • Knowlton, Kirk U;
    • Nadauld, Lincoln D;
    • Ullum, Henrik;
    • Pedersen, Ole Birger Vesterager;
    • Ostrowski, Sisse Rye;
    • Holm, Hilma;
    • Gudbjartsson, Daniel F;
    • Sulem, Patrick;
    • Stefansson, Kari
    Publication type:
    Article

  • Predicting the probability of death using proteomics.

    Published in:
    Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02289-6
    By:
    • Eiriksdottir, Thjodbjorg;
    • Ardal, Steinthor;
    • Jonsson, Benedikt A.;
    • Lund, Sigrun H.;
    • Ivarsdottir, Erna V.;
    • Norland, Kristjan;
    • Ferkingstad, Egil;
    • Stefansson, Hreinn;
    • Jonsdottir, Ingileif;
    • Holm, Hilma;
    • Rafnar, Thorunn;
    • Saemundsdottir, Jona;
    • Norddahl, Gudmundur L.;
    • Thorgeirsson, Gudmundur;
    • Gudbjartsson, Daniel F.;
    • Sulem, Patrick;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari;
    • Ulfarsson, Magnus O.
    Publication type:
    Article

  • The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis.

    Published in:
    Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02224-9
    By:
    • Ivarsdottir, Erna V.;
    • Holm, Hilma;
    • Benonisdottir, Stefania;
    • Olafsdottir, Thorhildur;
    • Sveinbjornsson, Gardar;
    • Thorleifsson, Gudmar;
    • Eggertsson, Hannes P.;
    • Halldorsson, Gisli H.;
    • Hjorleifsson, Kristjan E.;
    • Melsted, Pall;
    • Gylfason, Arnaldur;
    • Arnadottir, Gudny A.;
    • Oddsson, Asmundur;
    • Jensson, Brynjar O.;
    • Jonasdottir, Aslaug;
    • Jonasdottir, Adalbjorg;
    • Juliusdottir, Thorhildur;
    • Stefansdottir, Lilja;
    • Tragante, Vinicius;
    • Halldorsson, Bjarni V.
    Publication type:
    Article

  • Molecular benchmarks of a SARS-CoV-2 epidemic.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23883-6
    By:
    • Jonsson, Hakon;
    • Magnusson, Olafur T.;
    • Melsted, Pall;
    • Berglund, Jonas;
    • Agustsdottir, Arna B.;
    • Eiríksdottir, Berglind;
    • Fridriksdottir, Run;
    • Garðarsdottir, Elisabet Eir;
    • Georgsson, Gudmundur;
    • Gretarsdottir, Olafia S.;
    • Guðmundsson, Kjartan R.;
    • Gunnarsdottir, Thora Rosa;
    • Eggertsson, Hannes;
    • Gylfason, Arnaldur;
    • Holm, Hilma;
    • Jensson, Brynjar O.;
    • Jonasdottir, Aslaug;
    • Jonsson, Frosti;
    • Josefsdottir, Kamilla S.;
    • Thordardottir, Marianna
    Publication type:
    Article

  • Quadricuspid Aortic Valve.

    Published in:
    Texas Heart Institute Journal, 2004, v. 31, n. 4, p. 450
    By:
    • Holm, Hilma;
    • Jacobson, Stuart;
    • Reul, George J.;
    • Stainback, Raymond F.
    Publication type:
    Article

  • Identification of a large set of rare complete human knockouts.

    Published in:
    Nature Genetics, 2015, v. 47, n. 5, p. 448, doi. 10.1038/ng.3243
    By:
    • Sulem, Patrick;
    • Oddson, Asmundur;
    • Stefansson, Hreinn;
    • Gudjonsson, Sigurjon A;
    • Zink, Florian;
    • Hjartarson, Eirikur;
    • Sigurdsson, Gunnar Th;
    • Jonasdottir, Adalbjorg;
    • Jonasdottir, Aslaug;
    • Sigurdsson, Asgeir;
    • Magnusson, Olafur Th;
    • Masson, Gisli;
    • Helgason, Hannes;
    • Kong, Augustine;
    • Gudbjartsson, Daniel F;
    • Helgason, Agnar;
    • Holm, Hilma;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

    Published in:
    Nature Genetics, 2013, v. 45, n. 6, p. 621, doi. 10.1038/ng.2610
    By:
    • den Hoed, Marcel;
    • Eijgelsheim, Mark;
    • Esko, Tõnu;
    • Brundel, Bianca J J M;
    • Peal, David S;
    • Evans, David M;
    • Nolte, Ilja M;
    • Segrè, Ayellet V;
    • Holm, Hilma;
    • Handsaker, Robert E;
    • Westra, Harm-Jan;
    • Johnson, Toby;
    • Isaacs, Aaron;
    • Yang, Jian;
    • Lundby, Alicia;
    • Zhao, Jing Hua;
    • Kim, Young Jin;
    • Go, Min Jin;
    • Almgren, Peter;
    • Bochud, Murielle
    Publication type:
    Article

  • Identification of low-frequency variants associated with gout and serum uric acid levels.

    Published in:
    Nature Genetics, 2011, v. 43, n. 11, p. 1127, doi. 10.1038/ng.972
    By:
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F;
    • Walters, G Bragi;
    • Helgadottir, Hafdis T;
    • Helgason, Agnar;
    • Gudjonsson, Sigurjon A;
    • Zanon, Carlo;
    • Besenbacher, Soren;
    • Bjornsdottir, Gyda;
    • Magnusson, Olafur T;
    • Magnusson, Gisli;
    • Hjartarson, Eirikur;
    • Saemundsdottir, Jona;
    • Gylfason, Arnaldur;
    • Jonasdottir, Adalbjorg;
    • Holm, Hilma;
    • Karason, Ari;
    • Rafnar, Thorunn;
    • Stefansson, Hreinn;
    • Andreassen, Ole A
    Publication type:
    Article

  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

    Published in:
    Nature Genetics, 2011, v. 43, n. 11, p. 1131, doi. 10.1038/ng.970
    By:
    • Chambers, John C;
    • Zhang, Weihua;
    • Sehmi, Joban;
    • Li, Xinzhong;
    • Wass, Mark N;
    • Van der Harst, Pim;
    • Holm, Hilma;
    • Sanna, Serena;
    • Kavousi, Maryam;
    • Baumeister, Sebastian E;
    • Coin, Lachlan J;
    • Deng, Guohong;
    • Gieger, Christian;
    • Heard-Costa, Nancy L;
    • Hottenga, Jouke-Jan;
    • Kühnel, Brigitte;
    • Kumar, Vinod;
    • Lagou, Vasiliki;
    • Liang, Liming;
    • Luan, Jian'an
    Publication type:
    Article

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

    Published in:
    Nature Genetics, 2011, v. 43, n. 4, p. 333, doi. 10.1038/ng.784
    By:
    • Schunkert, Heribert;
    • König, Inke R.;
    • Kathiresan, Sekar;
    • Reilly, Muredach P.;
    • Assimes, Themistocles L.;
    • Holm, Hilma;
    • Preuss, Michael;
    • Stewart, Alexandre F. R.;
    • Barbalic, Maja;
    • Gieger, Christian;
    • Absher, Devin;
    • Aherrahrou, Zouhair;
    • Allayee, Hooman;
    • Altshuler, David;
    • Anand, Sonia S;
    • Andersen, Karl;
    • Anderson, Jeffrey L.;
    • Ardissino, Diego;
    • Ball, Stephen G.;
    • Balmforth, Anthony J.
    Publication type:
    Article

  • A rare variant in MYH6 is associated with high risk of sick sinus syndrome.

    Published in:
    Nature Genetics, 2011, v. 43, n. 4, p. 316, doi. 10.1038/ng.781
    By:
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.;
    • Sulem, Patrick;
    • Masson, Gisli;
    • Helgadottir, Hafdis Th;
    • Zanon, Carlo;
    • Magnusson, Olafur Th;
    • Helgason, Agnar;
    • Saemundsdottir, Jona;
    • Gylfason, Arnaldur;
    • Stefansdottir, Hrafnhildur;
    • Gretarsdottir, Solveig;
    • Matthiasson, Stefan E.;
    • Thorgeirsson, Guðmundur;
    • Jonasdottir, Aslaug;
    • Sigurdsson, Asgeir;
    • Stefansson, Hreinn;
    • Werge, Thomas;
    • Rafnar, Thorunn;
    • Kiemeney, Lambertus A.
    Publication type:
    Article

  • Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

    Published in:
    Nature Genetics, 2010, v. 42, n. 8, p. 692, doi. 10.1038/ng.622
    By:
    • Gretarsdottir, Solveig;
    • Baas, Annette F.;
    • Thorleifsson, Gudmar;
    • Holm, Hilma;
    • den Heijer, Martin;
    • de Vries, Jean-Paul P. M.;
    • Kranendonk, Steef E.;
    • Zeebregts, Clark J. A. M.;
    • van Sterkenburg, Steven M.;
    • Geelkerken, Robert H.;
    • van Rij, Andre M.;
    • Williams, Michael J. A.;
    • Boll, Albert P. M.;
    • Kostic, Jelena P.;
    • Jonasdottir, Adalbjorg;
    • Jonasdottir, Aslaug;
    • Walters, G. Bragi;
    • Masson, Gisli;
    • Sulem, Patrick;
    • Saemundsdottir, Jona
    Publication type:
    Article

  • Several common variants modulate heart rate, PR interval and QRS duration.

    Published in:
    Nature Genetics, 2010, v. 42, n. 2, p. 117, doi. 10.1038/ng.511
    By:
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.;
    • Arnar, David O.;
    • Thorleifsson, Gudmar;
    • Thorgeirsson, Gudmundur;
    • Stefansdottir, Hrafnhildur;
    • Gudjonsson, Sigurjon A.;
    • Jonasdottir, Aslaug;
    • Mathiesen, Ellisiv B.;
    • Njølstad, Inger;
    • Nyrnes, Audhild;
    • Wilsgaard, Tom;
    • Hald, Erin M.;
    • Hveem, Kristian;
    • Stoltenberg, Camilla;
    • Løchen, Maja-Lisa;
    • Kong, Augustine;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.

    Published in:
    Nature Genetics, 2009, v. 41, n. 8, p. 876, doi. 10.1038/ng.417
    By:
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma;
    • Gretarsdottir, Solveig;
    • Thorleifsson, Gudmar;
    • Walters, G. Bragi;
    • Thorgeirsson, Gudmundur;
    • Gulcher, Jeffrey;
    • Mathiesen, Ellisiv B.;
    • Njølstad, Inger;
    • Nyrnes, Audhild;
    • Wilsgaard, Tom;
    • Hald, Erin M.;
    • Hveem, Kristian;
    • Stoltenberg, Camilla;
    • Kucera, Gayle;
    • Stubblefield, Tanya;
    • Carter, Shannon;
    • Roden, Dan;
    • Ng, Maggie C. Y.;
    • Baum, Larry
    Publication type:
    Article

  • Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density.

    Published in:
    Nature Genetics, 2009, v. 41, n. 8, p. 926, doi. 10.1038/ng.404
    By:
    • Thorleifsson, Gudmar;
    • Holm, Hilma;
    • Edvardsson, Vidar;
    • Walters, G. Bragi;
    • Styrkarsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Sulem, Patrick;
    • Halldorsson, Bjarni V.;
    • de Vegt, Femmie;
    • d'Ancona, Frank C. H.;
    • den Heijer, Martin;
    • Franzson, Leifur;
    • Christiansen, Claus;
    • Alexandersen, Peter;
    • Rafnar, Thorunn;
    • Kristjansson, Kristleifur;
    • Sigurdsson, Gunnar;
    • Kiemeney, Lambertus A.;
    • Bodvarsson, Magnus;
    • Indridason, Olafur S.
    Publication type:
    Article

  • Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche.

    Published in:
    Nature Genetics, 2009, v. 41, n. 6, p. 734, doi. 10.1038/ng.383
    By:
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F.;
    • Rafnar, Thorunn;
    • Holm, Hilma;
    • Olafsdottir, Elinborg J.;
    • Olafsdottir, Gudridur H.;
    • Jonsson, Thorvaldur;
    • Alexandersen, Peter;
    • Feenstra, Bjarke;
    • Boyd, Heather A.;
    • Aben, Katja K.;
    • Verbeek, Andre L. M.;
    • Roeleveld, Nel;
    • Jonasdottir, Aslaug;
    • Styrkarsdottir, Unnur;
    • Steinthorsdottir, Valgerdur;
    • Karason, Ari;
    • Stacey, Simon N.;
    • Gudmundsson, Julius;
    • Jakobsdottir, Margret
    Publication type:
    Article

  • Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01313-8
    By:
    • Møller, Peter Loof;
    • Rohde, Palle Duun;
    • Dahl, Jonathan Nørtoft;
    • Rasmussen, Laust Dupont;
    • Nissen, Louise;
    • Schmidt, Samuel Emil;
    • McGilligan, Victoria;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari;
    • Holm, Hilma;
    • Bentzon, Jacob Fog;
    • Bøttcher, Morten;
    • Winther, Simon;
    • Nyegaard, Mette
    Publication type:
    Article

  • Genomic risk scores, biomolecules, and clinical conditions to predict atrial fibrillation: time to integrate what we can measure.

    Published in:
    European Heart Journal, 2023, v. 44, n. 3, p. 232, doi. 10.1093/eurheartj/ehac527
    By:
    • Kääb, Stefan;
    • Holm, Hilma;
    • Kirchhof, Paulus
    Publication type:
    Article

  • Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09304-9
    By:
    • Ivarsdottir, Erna V.;
    • Benonisdottir, Stefania;
    • Thorleifsson, Gudmar;
    • Sulem, Patrick;
    • Oddsson, Asmundur;
    • Styrkarsdottir, Unnur;
    • Kristmundsdottir, Snaedis;
    • Arnadottir, Gudny A.;
    • Thorgeirsson, Gudmundur;
    • Jonsdottir, Ingileif;
    • Zoega, Gunnar M.;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Jonasson, Fridbert;
    • Holm, Hilma;
    • Stefansson, Kari
    Publication type:
    Article

  • Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06920-9
    By:
    • Gudmundsson, Julius;
    • Sigurdsson, Jon K.;
    • Stefansdottir, Lilja;
    • Agnarsson, Bjarni A.;
    • Isaksson, Helgi J.;
    • Stefansson, Olafur A.;
    • Gudjonsson, Sigurjon A.;
    • Gudbjartsson, Daniel F.;
    • Masson, Gisli;
    • Frigge, Michael L.;
    • Stacey, Simon N.;
    • Sulem, Patrick;
    • Halldorsson, Gisli H.;
    • Tragante, Vinicius;
    • Holm, Hilma;
    • Eyjolfsson, Gudmundur I.;
    • Sigurdardottir, Olof;
    • Olafsson, Isleifur;
    • Jonsson, Thorvaldur;
    • Jonsson, Eirikur
    Publication type:
    Article

  • Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach.

    Published in:
    European Journal of Human Genetics, 2015, v. 23, n. 3, p. 381, doi. 10.1038/ejhg.2014.101
    By:
    • Versmissen, Jorie;
    • Oosterveer, Daniëlla M;
    • Yazdanpanah, Mojgan;
    • Dehghan, Abbas;
    • Hólm, Hilma;
    • Erdman, Jeanette;
    • Aulchenko, Yurii S;
    • Thorleifsson, Gudmar;
    • Schunkert, Heribert;
    • Huijgen, Roeland;
    • Vongpromek, Ranitha;
    • Uitterlinden, André G;
    • Defesche, Joep C;
    • van Duijn, Cornelia M;
    • Mulder, Monique;
    • Dadd, Tony;
    • Karlsson, Hróbjartur D;
    • Ordovas, Jose;
    • Kindt, Iris;
    • Jarman, Amelia
    Publication type:
    Article

  • The chromosome 9p21 risk locus is associated with angiographic severity and progression of coronary artery disease.

    Published in:
    European Heart Journal, 2010, v. 31, n. 24, p. 3017, doi. 10.1093/eurheartj/ehq272
    By:
    • Patel, Riyaz S.;
    • Su, Shaoyong;
    • Neeland, Ian J.;
    • Ahuja, Ayushi;
    • Veledar, Emir;
    • Zhao, Jinying;
    • Helgadottir, Anna;
    • Holm, Hilma;
    • Gulcher, Jeffrey R.;
    • Stefansson, Kari;
    • Waddy, Salina;
    • Vaccarino, Viola;
    • Zafari, A. Maziar;
    • Quyyumi, Arshed A.
    Publication type:
    Article

  • Variants conferring risk of atrial fibrillation on chromosome 4q25.

    Published in:
    Nature, 2007, v. 448, n. 7151, p. 353, doi. 10.1038/nature06007
    By:
    • Gudbjartsson, Daniel F.;
    • Arnar, David O.;
    • Helgadottir, Anna;
    • Gretarsdottir, Solveig;
    • Holm, Hilma;
    • Sigurdsson, Asgeir;
    • Jonasdottir, Adalbjorg;
    • Baker, Adam;
    • Thorleifsson, Gudmar;
    • Kristjansson, Kristleifur;
    • Palsson, Arnar;
    • Blondal, Thorarinn;
    • Sulem, Patrick;
    • Backman, Valgerdur M.;
    • Hardarson, Gudmundur A.;
    • Palsdottir, Ebba;
    • Helgason, Agnar;
    • Sigurjonsdottir, Runa;
    • Sverrisson, Jon T.;
    • Kostulas, Konstantinos
    Publication type:
    Article

  • Genetic Risk Score and Cardiovascular Events in Women.

    Published in:
    2010
    By:
    • Holm, Hilma;
    • Thorleifsson, Gudmar;
    • Stefansson, Kari
    Publication type:
    Letter

  • Loss-of-function variants in ITSN1 confer high risk of Parkinson's disease.

    Published in:
    NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00752-9
    By:
    • Skuladottir, Astros Th.;
    • Tragante, Vinicius;
    • Sveinbjornsson, Gardar;
    • Helgason, Hannes;
    • Sturluson, Arni;
    • Bjornsdottir, Anna;
    • Jonsson, Palmi;
    • Palmadottir, Vala;
    • Sveinsson, Olafur A.;
    • Jensson, Brynjar O.;
    • Gudjonsson, Sigurjon A.;
    • Ivarsdottir, Erna V.;
    • Gisladottir, Rosa S.;
    • Gunnarsson, Arni F.;
    • Walters, G. Bragi;
    • Jonsdottir, Gudrun A.;
    • Thorgeirsson, Thorgeir E.;
    • Bjornsdottir, Gyda;
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.
    Publication type:
    Article

  • Polygenic risk scores associate with blood pressure traits across the lifespan.

    Published in:
    European Journal of Preventive Cardiology, 2024, v. 31, n. 6, p. 644, doi. 10.1093/eurjpc/zwad365
    By:
    • Øvretveit, Karsten;
    • Ingeström, Emma M L;
    • Spitieris, Michail;
    • Tragante, Vinicius;
    • Wade, Kaitlin H;
    • Thomas, Laurent F;
    • Wolford, Brooke N;
    • Wisløff, Ulrik;
    • Gudbjartsson, Daniel F;
    • Holm, Hilma;
    • Stefansson, Kari;
    • Brumpton, Ben M;
    • Hveem, Kristian
    Publication type:
    Article

  • Epigenetic and genetic components of height regulation.

    Published in:
    Nature Communications, 2016, v. 7, n. 11, p. 13490, doi. 10.1038/ncomms13490
    By:
    • Benonisdottir, Stefania;
    • Oddsson, Asmundur;
    • Helgason, Agnar;
    • Kristjansson, Ragnar P.;
    • Sveinbjornsson, Gardar;
    • Oskarsdottir, Arna;
    • Thorleifsson, Gudmar;
    • Davidsson, Olafur B.;
    • Arnadottir, Gudny A.;
    • Sulem, Gerald;
    • Jensson, Brynjar O.;
    • Holm, Hilma;
    • Alexandersson, Kristjan F.;
    • Tryggvadottir, Laufey;
    • Walters, G. Bragi;
    • Gudjonsson, Sigurjon A.;
    • Ward, Lucas D.;
    • Sigurdsson, Jon K.;
    • Iordache, Paul D.;
    • Frigge, Michael L.
    Publication type:
    Article

  • Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase.

    Published in:
    Nature Communications, 2016, v. 7, n. 2, p. 10572, doi. 10.1038/ncomms10572
    By:
    • Kristjansson, Ragnar P.;
    • Oddsson, Asmundur;
    • Helgason, Hannes;
    • Sveinbjornsson, Gardar;
    • Arnadottir, Gudny A.;
    • Jensson, Brynjar O.;
    • Jonasdottir, Aslaug;
    • Jonasdottir, Adalbjorg;
    • Bragi Walters, G.;
    • Sulem, Gerald;
    • Oskarsdottir, Arna;
    • Benonisdottir, Stefania;
    • Davidsson, Olafur B.;
    • Masson, Gisli;
    • Th Magnusson, Olafur;
    • Holm, Hilma;
    • Sigurdardottir, Olof;
    • Jonsdottir, Ingileif;
    • Eyjolfsson, Gudmundur I.;
    • Olafsson, Isleifur
    Publication type:
    Article

  • Common and rare variants associated with kidney stones and biochemical traits.

    Published in:
    Nature Communications, 2015, v. 6, n. 8, p. 7975, doi. 10.1038/ncomms8975
    By:
    • Oddsson, Asmundur;
    • Sulem, Patrick;
    • Helgason, Hannes;
    • Edvardsson, Vidar O.;
    • Thorleifsson, Gudmar;
    • Sveinbjörnsson, Gardar;
    • Haraldsdottir, Eik;
    • Eyjolfsson, Gudmundur I.;
    • Sigurdardottir, Olof;
    • Olafsson, Isleifur;
    • Masson, Gisli;
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.;
    • Thorsteinsdottir, Unnur;
    • Indridason, Olafur S.;
    • Palsson, Runolfur;
    • Stefansson, Kari
    Publication type:
    Article

  • Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

    Published in:
    Annals of Neurology, 2008, v. 64, n. 4, p. 402, doi. 10.1002/ana.21480
    By:
    • Gretarsdottir, Solveig;
    • Thorleifsson, Gudmar;
    • Manolescu, Andrei;
    • Styrkarsdottir, Unnur;
    • Helgadottir, Anna;
    • Gschwendtner, Andreas;
    • Kostulas, Konstantinos;
    • Kuhlenbäumer, Gregor;
    • Bevan, Steve;
    • Jonsdottir, Thorbjorg;
    • Bjarnason, Hjordis;
    • Saemundsdottir, Jona;
    • Palsson, Stefan;
    • Arnar, David O.;
    • Holm, Hilma;
    • Thorgeirsson, Gudmundur;
    • Valdimarsson, Einar Mar;
    • Sveinbjörnsdottir, Sigurlaug;
    • Gieger, Christian;
    • Berger, Klaus
    Publication type:
    Article

  • Thirty novel sequence variants impacting human intracranial volume.

    Published in:
    Brain Communications, 2022, v. 4, n. 6, p. 1, doi. 10.1093/braincomms/fcac271
    By:
    • Nawaz, Muhammad Sulaman;
    • Einarsson, Gudmundur;
    • Bustamante, Mariana;
    • Gisladottir, Rosa S.;
    • Walters, G. Bragi;
    • Jonsdottir, Gudrun A.;
    • Skuladottir, Astros Th.;
    • Bjornsdottir, Gyda;
    • Magnusson, Sigurdur H.;
    • Asbjornsdottir, Bergrun;
    • Unnsteinsdottir, Unnur;
    • Sigurdsson, Engilbert;
    • Jonsson, Palmi V.;
    • Palmadottir, Vala Kolbrun;
    • Gudjonsson, Sigurjon A.;
    • Halldorsson, Gisli H.;
    • Ferkingstad, Egil;
    • Jonsdottir, Ingileif;
    • Thorleifsson, Gudmar;
    • Holm, Hilma
    Publication type:
    Article

  • Polygenic Interactions With Environmental Exposures in Blood Pressure Regulation: The HUNT Study.

    Published in:
    Journal of the American Heart Association, 2024, v. 13, n. 19, p. 1, doi. 10.1161/JAHA.123.034612
    By:
    • Øvretveit, Karsten;
    • Ingeström, Emma M. L.;
    • Spitieris, Michail;
    • Tragante, Vinicius;
    • Thomas, Laurent F.;
    • Steinsland, Ingelin;
    • Brumpton, Ben M.;
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma;
    • Stefansson, Kari;
    • Wisløff, Ulrik;
    • Hveem, Kristian
    Publication type:
    Article

  • Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland.

    Published in:
    Journal of the American Heart Association, 2023, v. 12, n. 14, p. 1, doi. 10.1161/JAHA.123.029845
    By:
    • Sveinbjornsson, Gardar;
    • Benediktsdottir, Bara D.;
    • Sigfusson, Gunnlaugur;
    • Norland, Kristjan;
    • Davidsson, Olafur B.;
    • Thorolfsdottir, Rosa B.;
    • Tragante, Vinicius;
    • Arnadottir, Gudny A.;
    • Jensson, Brynjar O.;
    • Katrinardottir, Hildigunnur;
    • Fridriksdottir, Run;
    • Gudmundsdottir, Hallbera;
    • Aegisdottir, Hildur M.;
    • Fridriksson, Brynjar;
    • Thorgeirsson, Gudmundur;
    • Magnusson, Vidar;
    • Oddsson, Asmundur;
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma
    Publication type:
    Article

  • Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden.

    Published in:
    2020
    By:
    • Christiansen, Morten Krogh;
    • Nissen, Louise;
    • Winther, Simon;
    • Møller, Peter Loof;
    • Frost, Lars;
    • Johansen, Jane Kirk;
    • Jensen, Henrik Kjærulf;
    • Guðbjartsson, Daníel;
    • Holm, Hilma;
    • Stefánsson, Kári;
    • Bøtker, Hans Erik;
    • Bøttcher, Morten;
    • Nyegaard, Mette
    Publication type:
    journal article

  • Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.

    Published in:
    2015
    By:
    • Kaess, Bernhard M.;
    • Preis, Sarah R.;
    • Lieb, Wolfgang;
    • Beiser, Alexa S.;
    • Yang, Qiong;
    • Chen, Tai C.;
    • Hengstenberg, Christian;
    • Erdmann, Jeanette;
    • Schunkert, Heribert;
    • Seshadri, Sudha;
    • Vasan, Ramachandran S.;
    • CARDIoGRAM;
    • Assimes, Themistocles L;
    • Deloukas, Panos;
    • Holm, Hilma;
    • Kathiresan, Sekar;
    • König, Inke R;
    • McPherson, Ruth;
    • Reilly, Muredach P;
    • Roberts, Robert
    Publication type:
    journal article

  • Rare mutations associating with serum creatinine and chronic kidney disease.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 25, p. 6935, doi. 10.1093/hmg/ddu399
    By:
    • Sveinbjornsson, Gardar;
    • Mikaelsdottir, Evgenia;
    • Palsson, Runolfur;
    • Indridason, Olafur S.;
    • Holm, Hilma;
    • Jonasdottir, Aslaug;
    • Helgason, Agnar;
    • Sigurdsson, Snaevar;
    • Jonasdottir, Adalbjorg;
    • Sigurdsson, Asgeir;
    • Eyjolfsson, Gudmundur Ingi;
    • Sigurdardottir, Olof;
    • Magnusson, Olafur Th.;
    • Kong, Augustine;
    • Masson, Gisli;
    • Sulem, Patrick;
    • Olafsson, Isleifur;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • Rare mutations associating with serum creatinine and chronic kidney disease.

    Published in:
    Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu399
    By:
    • Sveinbjornsson, Gardar;
    • Mikaelsdottir, Evgenia;
    • Palsson, Runolfur;
    • Indridason, Olafur S.;
    • Holm, Hilma;
    • Jonasdottir, Aslaug;
    • Helgason, Agnar;
    • Sigurdsson, Snaevar;
    • Jonasdottir, Adalbjorg;
    • Sigurdsson, Asgeir;
    • Eyjolfsson, Gudmundur Ingi;
    • Sigurdardottir, Olof;
    • Magnusson, Olafur Th.;
    • Kong, Augustine;
    • Masson, Gisli;
    • Sulem, Patrick;
    • Olafsson, Isleifur;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • Sequence variants at CYP1A1–CYP1A2 and AHR associate with coffee consumption.

    Published in:
    Human Molecular Genetics, 2011, v. 20, n. 10, p. 2071, doi. 10.1093/hmg/ddr086
    By:
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F.;
    • Geller, Frank;
    • Prokopenko, Inga;
    • Feenstra, Bjarke;
    • Aben, Katja K.H.;
    • Franke, Barbara;
    • den Heijer, Martin;
    • Kovacs, Peter;
    • Stumvoll, Michael;
    • Mägi, Reedik;
    • Yanek, Lisa R.;
    • Becker, Lewis C.;
    • Boyd, Heather A.;
    • Stacey, Simon N.;
    • Walters, G. Bragi;
    • Jonasdottir, Adalbjorg;
    • Thorleifsson, Gudmar;
    • Holm, Hilma;
    • Gudjonsson, Sigurjon A.
    Publication type:
    Article

  • Genetic Correction of PSA Values Using Sequence Variants Associated with PSA Levels.

    Published in:
    Science Translational Medicine, 2010, v. 2, n. 62, p. 1, doi. 10.1126/scitranslmed.3001513
    By:
    • Gudmundsson, Julius;
    • Besenbacher, Soren;
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F.;
    • Olafsson, Isleifur;
    • Arinbjarnarson, Sturla;
    • Agnarsson, Bjarni A.;
    • Benediktsdottir, Kristrun R.;
    • Isaksson, Helgi J.;
    • Kostic, Jelena P.;
    • Gudjonsson, Sigurjon A.;
    • Stacey, Simon N.;
    • Gylfason, Arnaldur;
    • Sigurdsson, Asgeir;
    • Holm, Hilma;
    • Bjornsdottir, Unnur S.;
    • Eyjolfsson, Gudmundur I.;
    • Navarrete, Sebastian;
    • Fuertes, Fernando;
    • Garcia-Prats, Maria D.
    Publication type:
    Article

  • A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin.

    Published in:
    Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0053-3
    By:
    • Oskarsson, Gudjon R.;
    • Kristjansson, Ragnar P.;
    • Lee, Amy L.;
    • Sveinbjornsson, Gardar;
    • Magnusson, Magnus K.;
    • Ivarsdottir, Erna V.;
    • Benonisdottir, Stefania;
    • Oddsson, Asmundur;
    • Davidsson, Olafur B.;
    • Saemundsdottir, Jona;
    • Halldorsson, Gisli H.;
    • Arthur, Joseph;
    • Arnadottir, Gudny A.;
    • Masson, Gisli;
    • Jensson, Brynjar O.;
    • Holm, Hilma;
    • Olafsson, Isleifur;
    • Onundarson, Pall T.;
    • Gudbjartsson, Daniel F.;
    • Norddahl, Gudmundur L.
    Publication type:
    Article

  • Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR ) Gene.

    Published in:
    PLoS Genetics, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.pgen.1001035
    By:
    • Kapur, Karen;
    • Johnson, Toby;
    • Beckmann, Noam D.;
    • Sehmi, Joban;
    • Tanaka, Toshiko;
    • Kutalik, Zoltán;
    • Styrkarsdottir, Unnur;
    • Weihua Zhang;
    • Marek, Diana;
    • Gudbjartsson, Daniel F.;
    • Milaneschi, Yuri;
    • Holm, Hilma;
    • DiIorio, Angelo;
    • Waterworth, Dawn;
    • Yun Li;
    • Singleton, Andrew B.;
    • Bjornsdottir, Unnur S.;
    • Sigurdsson, Gunnar;
    • Hernandez, Dena G.;
    • DeSilva, Ranil
    Publication type:
    Article

  • Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones-Role of Age and Comorbid Diseases.

    Published in:
    PLoS Genetics, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.pgen.1001039
    By:
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma;
    • Indridason, Olafur S.;
    • Thorleifsson, Gudmar;
    • Edvardsson, Vidar;
    • Sulem, Patrick;
    • de Vegt, Femmie;
    • d'Ancona, Frank C. H.;
    • den Heijer, Martin;
    • Franzson, Leifur;
    • Rafnar, Thorunn;
    • Kristjansson, Kristleifur;
    • Bjornsdottir, Unnur S.;
    • Eyjolfsson, Gudmundur I.;
    • Kiemeney, Lambertus A.;
    • Kong, Augustine;
    • Palsson, Runolfur;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".

    Published in:
    Science Translational Medicine, 2021, v. 13, n. 622, p. 1, doi. 10.1126/scitranslmed.abe8497
    By:
    • Hólm, Hilma;
    • Sulem, Patrick;
    • Tragante, Vinicius;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • A frameshift deletion in the sarcomere gene MYL4 causes early-onset familial atrial fibrillation.

    Published in:
    European Heart Journal, 2017, v. 38, n. 1, p. 1, doi. 10.1093/eurheartj/ehw379
    By:
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma;
    • Sulem, Patrick;
    • Masson, Gisli;
    • Oddsson, Asmundur;
    • Magnusson, Olafur Th.;
    • Saemundsdottir, Jona;
    • Helgadottir, Hafdis Th.;
    • Helgason, Hannes;
    • Johannsdottir, Hrefna;
    • Gretarsdottir, Solveig;
    • Gudjonsson, Sigurjon A.;
    • Njølstad, Inger;
    • Løchen, Maja-Lisa;
    • Baum, Larry;
    • Ma, Ronald C.W.;
    • Sigfusson, Gunnlaugur;
    • Kong, Augustine;
    • Thorgeirsson, Guðmundur;
    • Sverrisson, Jon Th.
    Publication type:
    Article

  • Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias.

    Published in:
    PLoS Medicine, 2012, v. 9, n. 2, p. 1
    By:
    • Clarke, Robert;
    • Bennett, Derrick A.;
    • Parish, Sarah;
    • Verhoef, Petra;
    • Dötsch-Klerk, Mariska;
    • Lathrop, Mark;
    • Xu, Peng;
    • Nordestgaard, Børge G.;
    • Holm, Hilma;
    • Hopewell, Jemma C.;
    • Saleheen, Danish;
    • Tanaka, Toshihiro;
    • Anand, Sonia S.;
    • Chambers, John C.;
    • Kleber, Marcus E.;
    • Ouwehand, Willem H.;
    • Yamada, Yoshiji;
    • Elbers, Clara;
    • Peters, Bas;
    • Stewart, Alexandre F. R.
    Publication type:
    Article

  • The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large‐Scale Proteomics Scan in Iceland.

    Published in:
    Arthritis & Rheumatology, 2021, v. 73, n. 11, p. 2025, doi. 10.1002/art.41793
    By:
    • Styrkarsdottir, Unnur;
    • Lund, Sigrun H.;
    • Saevarsdottir, Saedis;
    • Magnusson, Magnus I.;
    • Gunnarsdottir, Kristbjorg;
    • Norddahl, Gudmundur L.;
    • Frigge, Michael L.;
    • Ivarsdottir, Erna V.;
    • Bjornsdottir, Gyda;
    • Holm, Hilma;
    • Thorgeirsson, Gudmundur;
    • Rafnar, Thorunn;
    • Jonsdottir, Ingileif;
    • Ingvarsson, Thorvaldur;
    • Jonsson, Helgi;
    • Sulem, Patrick;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel;
    • Stefansson, Kari
    Publication type:
    Article

  • MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17315-0
    By:
    • Surakka, Ida;
    • Fritsche, Lars G.;
    • Zhou, Wei;
    • Backman, Joshua;
    • Kosmicki, Jack A.;
    • Lu, Haocheng;
    • Brumpton, Ben;
    • Nielsen, Jonas B.;
    • Gabrielsen, Maiken E.;
    • Skogholt, Anne Heidi;
    • Wolford, Brooke;
    • Graham, Sarah E.;
    • Chen, Y. Eugene;
    • Lee, Seunggeun;
    • Kang, Hyun Min;
    • Langhammer, Arnulf;
    • Forsmo, Siri;
    • Åsvold, Bjørn O.;
    • Styrkarsdottir, Unnur;
    • Holm, Hilma
    Publication type:
    Article