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Mass balance and metabolite profiling of 14C-guadecitabine in patients with advanced cancer.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 4, p. 1085, doi. 10.1007/s10637-019-00854-9
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- Publication type:
- Article
Pharmacokinetics and excretion of C-omacetaxine in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2016, v. 34, n. 5, p. 565, doi. 10.1007/s10637-016-0360-9
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- Publication type:
- Article
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.
- Published in:
- Investigational New Drugs, 2016, v. 34, n. 3, p. 300, doi. 10.1007/s10637-016-0342-y
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- Publication type:
- Article
Pharmacokinetics and excretion of C-lenvatinib in patients with advanced solid tumors or lymphomas.
- Published in:
- Investigational New Drugs, 2015, v. 33, n. 1, p. 233, doi. 10.1007/s10637-014-0181-7
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- Publication type:
- Article
Human metabolism of [14C]indisulam following i.v. infusion in cancer patients.
- Published in:
- Investigational New Drugs, 2005, v. 23, n. 4, p. 317, doi. 10.1007/s10637-005-1440-4
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- Publication type:
- Article
No relation between docetaxel administration route and high‐grade diarrhea incidence.
- Published in:
- Pharmacology Research & Perspectives, 2020, v. 8, n. 4, p. 1, doi. 10.1002/prp2.633
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- Publication type:
- Article
Population pharmacokinetic and adverse event analysis of topotecan in patients with solid tumors.
- Published in:
- Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 5, p. 334, doi. 10.1067/mcp.2002.123553
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- Publication type:
- Article
A rapid and simple HPLC-UV method for the determination of inhibition characteristics of farnesyl transferase inhibitors.
- Published in:
- Biomedical Chromatography, 2006, v. 20, n. 2, p. 161, doi. 10.1002/bmc.545
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- Publication type:
- Article
A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry.
- Published in:
- Biomedical Chromatography, 2006, v. 20, n. 1, p. 139, doi. 10.1002/bmc.544
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- Publication type:
- Article
A more sensitive MS detector does not obviously lead to a more sensitive assay: experiences with ES-285.
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- Biomedical Chromatography, 2004, v. 18, n. 6, p. 403, doi. 10.1002/bmc.404
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- Publication type:
- Article
Toxicological analysis of azide and cyanide for azide intoxications using gas chromatography.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2021, v. 128, n. 3, p. 534, doi. 10.1111/bcpt.13523
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- Publication type:
- Article
Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response.
- Published in:
- Nature Communications, 2014, v. 5, n. 11, p. 5275, doi. 10.1038/ncomms6275
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- Publication type:
- Article
Urinary excretion of paclitaxel and metabolites in a large series of study.
- Published in:
- Journal of Oncology Pharmacy Practice, 1998, v. 4, n. 3, p. 159, doi. 10.1177/107815529800400304
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- Publication type:
- Article
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 12, p. 3001, doi. 10.1007/s11095-023-03615-9
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- Publication type:
- Article
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 5, p. 1, doi. 10.1007/s11095-020-02828-6
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- Publication type:
- Article
Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.
- Published in:
- European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1075, doi. 10.1007/s00228-020-02888-y
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- Publication type:
- Article
The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases.
- Published in:
- European Journal of Clinical Pharmacology, 2018, v. 74, n. 6, p. 737, doi. 10.1007/s00228-018-2426-4
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- Publication type:
- Article
Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 6, p. 514, doi. 10.1007/s00280-002-0516-5
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- Publication type:
- Article
Clinical pharmacokinetics, pharmacodynamics and metabolism of the novel matrix metalloproteinase inhibitor ABT-518.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 6, p. 473, doi. 10.1007/s00280-002-0515-6
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- Publication type:
- Article
Urinary and fecal excretion of topotecan in patients with malignant solid tumours.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 1, p. 59, doi. 10.1007/s00280-002-0454-2
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- Publication type:
- Article
Population pharmacokinetics of the novel anticancer agent KRN7000.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 49, n. 4, p. 287, doi. 10.1007/s00280-001-0413-3
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- Publication type:
- Article
A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2001, v. 47, n. 4, p. 347, doi. 10.1007/s002800000226
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- Publication type:
- Article
A Phase 1 Dose‐Escalation Study of Low‐Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.
- Published in:
- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 6, p. 607, doi. 10.1002/cpdd.880
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- Publication type:
- Article
Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.
- Published in:
- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 5, p. 552, doi. 10.1002/cpdd.840
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- Publication type:
- Article
Quantitative analysis of EO9 (apaziquone) and its metabolite EO5a in human plasma by high-performance liquid chromatography under basic conditions coupled to electrospray tandem mass spectrometry.
- Published in:
- Journal of Mass Spectrometry, 2006, v. 41, n. 10, p. 1268, doi. 10.1002/jms.1086
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- Publication type:
- Article
Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.
- Published in:
- Journal of Mass Spectrometry, 2004, v. 39, n. 10, p. 1122, doi. 10.1002/jms.687
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- Publication type:
- Article
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N<sup>'</sup>,N<sup>"</sup>-triethylenethiophosphoramide (thiotepa) and N,N<sup>'</sup>,N<sup>"</sup>-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
- Published in:
- Journal of Mass Spectrometry, 2004, v. 39, n. 3, p. 262
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- Publication type:
- Article
Exposure‐Response Assessment of Enzalutamide and Its Major Metabolites in a Real‐World Cohort of Patients with Metastatic Castration‐Resistant Prostate Cancer.
- Published in:
- Pharmacotherapy, 2019, v. 39, n. 12, p. 1137, doi. 10.1002/phar.2339
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- Publication type:
- Article
The effect of complementary and alternative medicines on CYP3A4-mediated metabolism of three different substrates: 7-benzyloxy-4-trifluoromethyl-coumarin, midazolam and docetaxel.
- Published in:
- Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 6, p. 865, doi. 10.1111/jphp.12208
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- Publication type:
- Article
Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 5, p. 1211, doi. 10.1093/jac/dks011
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- Publication type:
- Article
Phase I Study of Afatinib and Selumetinib in Patients with KRAS‐Mutated Colorectal, Non‐Small Cell Lung, and Pancreatic Cancer.
- Published in:
- Oncologist, 2021, v. 26, n. 4, p. 290, doi. 10.1002/onco.13631
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- Publication type:
- Article
Protein versus DNA as a marker for peripheral blood mononuclear cell counting.
- Published in:
- Analytical & Bioanalytical Chemistry, 2009, v. 395, n. 3, p. 863, doi. 10.1007/s00216-009-3022-3
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- Publication type:
- Article
Application of dried blood spots combined with high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry for simultaneous quantification of vincristine and actinomycin-D.
- Published in:
- Analytical & Bioanalytical Chemistry, 2009, v. 394, n. 4, p. 1171, doi. 10.1007/s00216-009-2775-z
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- Publication type:
- Article
Bioanalytical methods for pharmacokinetic studies of antileishmanial drugs.
- Published in:
- Biomedical Chromatography, 2023, v. 37, n. 7, p. 1, doi. 10.1002/bmc.5519
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- Publication type:
- Article
A review of the bioanalytical methods for the quantitative determination of capecitabine and its metabolites in biological matrices.
- Published in:
- Biomedical Chromatography, 2020, v. 34, n. 1, p. N.PAG, doi. 10.1002/bmc.4732
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- Publication type:
- Article
Bioanalytical LC–MS/MS validation of therapeutic drug monitoring assays in oncology.
- Published in:
- Biomedical Chromatography, 2020, v. 34, n. 1, p. N.PAG, doi. 10.1002/bmc.4623
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- Publication type:
- Article
Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.
- Published in:
- Biomedical Chromatography, 2014, v. 28, n. 2, p. 302, doi. 10.1002/bmc.3021
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- Publication type:
- Article
A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5′-deoxy-5-fluorocytidine, 5′-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma.
- Published in:
- Biomedical Chromatography, 2010, v. 24, n. 4, p. 374, doi. 10.1002/bmc.1302
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- Publication type:
- Article
The bioanalysis of vinorelbine and 4- O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass-spectrometry.
- Published in:
- Biomedical Chromatography, 2009, v. 23, n. 12, p. 1316, doi. 10.1002/bmc.1255
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- Publication type:
- Article
High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature.
- Published in:
- Biomedical Chromatography, 2010, v. 24, n. 1, p. 83, doi. 10.1002/bmc.1271
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- Publication type:
- Article
Mass spectrometry in the quantitative analysis of therapeutic intracellular nucleotide analogs.
- Published in:
- Mass Spectrometry Reviews, 2011, v. 30, n. 2, p. 321, doi. 10.1002/mas.20280
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- Publication type:
- Article
Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.
- Published in:
- Mass Spectrometry Reviews, 2005, v. 24, n. 6, p. 887, doi. 10.1002/mas.20046
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- Publication type:
- Article
Pharmacokinetics and Excretion of C-Bendamustine in Patients with Relapsed or Refractory Malignancy.
- Published in:
- Drugs in R&D, 2013, v. 13, n. 1, p. 17, doi. 10.1007/s40268-012-0001-5
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- Publication type:
- Article
Is Higher Docetaxel Clearance in Prostate Cancer Patients Explained by Higher CYP3A? An In Vivo Phenotyping Study with Midazolam.
- Published in:
- Journal of Clinical Pharmacology, 2024, v. 64, n. 2, p. 155, doi. 10.1002/jcph.2362
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- Publication type:
- Article
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.
- Published in:
- 2007
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- Publication type:
- journal article
A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.
- Published in:
- Journal of Oncology Pharmacy Practice, 2023, v. 29, n. 4, p. 899, doi. 10.1177/10781552221089243
- By:
- Publication type:
- Article
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 82, n. 3, p. 706, doi. 10.1111/bcp.13007
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- Publication type:
- Article
Exploring the intracellular pharmacokinetics of the 5-fluorouracil nucleotides during capecitabine treatment.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 81, n. 5, p. 949, doi. 10.1111/bcp.12877
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- Publication type:
- Article
The effect of Echinacea purpurea on the pharmacokinetics of docetaxel.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 76, n. 3, p. 467, doi. 10.1111/bcp.12159
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- Publication type:
- Article
Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.
- Published in:
- Drugs in R&D, 2021, v. 21, n. 1, p. 103, doi. 10.1007/s40268-020-00336-x
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- Publication type:
- Article