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The t(8;21) fusion protein, AML1?ETO, specifically represses the transcription of the p14<sup>ARF</sup> tumor suppressor in acute myeloid leukemia.
- Published in:
- Nature Medicine, 2002, v. 8, n. 7, p. 743, doi. 10.1038/nm726
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- Article
Jedi‐1/MEGF12‐mediated phagocytosis controls the pro‐neurogenic properties of microglia in the ventricular‐subventricular zone.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079215
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- Article
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
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- Journal of Clinical Investigation, 2015, v. 125, n. 3, p. 1111, doi. 10.1172/JCI77088
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- Article
HDAC3 is essential for DNA replication in hematopoietic progenitor cells.
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- Journal of Clinical Investigation, 2013, v. 123, n. 7, p. 3112, doi. 10.1172/JCI60806
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- Article
Identification of active miRNA promoters from nuclear run-on RNA sequencing.
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- Nucleic Acids Research, 2017, v. 45, n. 13, p. 1, doi. 10.1093/nar/gkx318
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- Article
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.
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- Nucleic Acids Research, 2013, v. 41, n. 1, p. 90
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- Article
The enemy within: dormant retroviruses awaken.
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- Nature Medicine, 2010, v. 16, n. 5, p. 517, doi. 10.1038/nm0510-517
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- Article
AML-1 steps up to the platelets.
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- Nature Medicine, 2004, v. 10, n. 3, p. 238, doi. 10.1038/nm0304-238
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- Article
Inhibition of <i>Histone Deacetylase 3</i> Causes Replication Stress in Cutaneous T Cell Lymphoma.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068915
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- Article
Kaiso Directs the Transcriptional Corepressor MTG16 to the Kaiso Binding Site in Target Promoters.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051205
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- Article
Histone Deacetylase 3 Depletion in Osteo/ Chondroprogenitor Cells Decreases Bone Density and Increases Marrow Fat.
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- PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011492
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- Article
Inactivation of the p19.
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- Journal of Cellular Biochemistry, 2008, v. 104, n. 6, p. 2228, doi. 10.1002/jcb.21779
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- Article
Cellular stress triggers TEL nuclear export via two genetically separable pathways.
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- Journal of Cellular Biochemistry, 2008, v. 104, n. 2, p. 488, doi. 10.1002/jcb.21637
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- Article
Translating the histone code into leukemia.
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- Journal of Cellular Biochemistry, 2005, v. 96, n. 5, p. 938, doi. 10.1002/jcb.20604
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- Article
Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia.
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- Journal of Cellular Biochemistry, 1999, v. 75, p. 51, doi. 10.1002/(SICI)1097-4644(1999)75:32+<51::AID-JCB7>3.0.CO;2-S
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- Article
Role of histone deacetylases in acute leukemia.
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- Journal of Cellular Biochemistry, 1998, v. 72, p. 194, doi. 10.1002/(SICI)1097-4644(1998)72:30/31+<194::AID-JCB24>3.0.CO;2-H
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- Article
CBFa(AML/PEBP2)-related elements in the TGF-β type I receptor promoter and expression with osteoblast differentiation.
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- Journal of Cellular Biochemistry, 1998, v. 69, n. 3, p. 353, doi. 10.1002/(SICI)1097-4644(19980601)69:3<353::AID-JCB12>3.0.CO;2-D
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- Article
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
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- Journal of Cellular Biochemistry, 1997, v. 66, n. 1, p. 1, doi. 10.1002/(SICI)1097-4644(19970701)66:1<1::AID-JCB1>3.0.CO;2-V
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- Article
Role of RUNX family members in transcriptional repression and gene silencing.
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- Oncogene, 2004, v. 23, n. 24, p. 4220, doi. 10.1038/sj.onc.1207122
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- Article
Nomenclature for Runt-related (RUNX) proteins.
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- Oncogene, 2004, v. 23, n. 24, p. 4209, doi. 10.1038/sj.onc.1207758
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- Article
Loss of neurofibromatosis-1 and p19[sup ARF] cooperate to induce a multiple tumor phenotype.
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- Oncogene, 2002, v. 21, n. 32, p. 4978, doi. 10.1038/sj.onc.1205632
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- Article
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
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- Oncogene, 2001, v. 20, n. 48, p. 6983, doi. 10.1038/sj.onc.1204892
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- Article
TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3.
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- Oncogene, 2001, v. 20, n. 28, p. 3716, doi. 10.1038/sj.onc.1204479
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- Article
Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence.
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- EMBO Journal, 2012, v. 31, n. 6, p. 1494, doi. 10.1038/emboj.2011.500
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- Article
Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks.
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- EMBO Journal, 2008, v. 27, n. 7, p. 1017, doi. 10.1038/emboj.2008.51
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- Article
E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation.
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- Oncogene, 2001, v. 20, n. 8, p. 910, doi. 10.1038/sj.onc.1204171
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- Article
The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation.
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- FASEB Journal, 2015, v. 29, n. 3, p. 786, doi. 10.1096/fj.14-254284
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- Article
BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.
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- Journal of Cellular Biochemistry, 2019, v. 120, n. 5, p. 7309, doi. 10.1002/jcb.28005
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- Article
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.
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- Nature Communications, 2017, v. 8, n. 7, p. 1, doi. 10.1038/s41467-017-00182-7
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Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
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- Science Translational Medicine, 2020, v. 12, n. 534, p. 1, doi. 10.1126/scitranslmed.aaw8275
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- Article
Autofluorescence imaging identifies tumor cell‐cycle status on a single‐cell level.
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- Journal of Biophotonics, 2018, v. 11, n. 1, p. 1, doi. 10.1002/jbio.201600276
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- Article
Epigenetic regulation of tumor suppressors in t(8:21)-containing AML.
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- Annals of Hematology, 2004, v. 83, n. 6, p. 329, doi. 10.1007/s00277-003-0841-8
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- Article
Histone deacetylase 3 controls a transcriptional network required for B cell maturation.
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- Nucleic Acids Research, 2019, v. 47, n. 20, p. 10612, doi. 10.1093/nar/gkz816
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The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5′ and 3′ ends of genes.
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- Nucleic Acids Research, 2019, v. 47, n. 8, p. 3921, doi. 10.1093/nar/gkz127
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- Article
Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation.
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- BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-5016-z
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- Article