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Histone lysine demethylases as targets for anticancer therapy.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Histone lysine demethylases as targets for anticancer therapy.
- Published in:
- Nature Reviews Drug Discovery, 2013, v. 12, n. 12, p. 917, doi. 10.1038/nrd4154
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- Publication type:
- Article
The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis.
- Published in:
- Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/5451038
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- Publication type:
- Article
BTK inhibitors synergise with 5‐FU to treat drug‐resistant TP53‐null colon cancers.
- Published in:
- Journal of Pathology, 2020, v. 250, n. 2, p. 134, doi. 10.1002/path.5347
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- Publication type:
- Article
The E2F family: specific functions and overlapping interests.
- Published in:
- EMBO Journal, 2004, v. 23, n. 24, p. 4709, doi. 10.1038/sj.emboj.7600481
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- Publication type:
- Article
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity.
- Published in:
- EMBO Journal, 2004, v. 23, n. 20, p. 4061, doi. 10.1038/sj.emboj.7600402
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- Publication type:
- Article
Human Geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis.
- Published in:
- EMBO Journal, 2004, v. 23, n. 15, p. 3122, doi. 10.1038/sj.emboj.7600314
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- Publication type:
- Article
E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes.
- Published in:
- EMBO Journal, 2003, v. 22, n. 23, p. 6289, doi. 10.1093/emboj/cdg613
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- Publication type:
- Article
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
- Published in:
- EMBO Journal, 2001, v. 20, n. 22, p. 6371, doi. 10.1093/emboj/20.22.6371
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- Publication type:
- Article
Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its subcellular localization.
- Published in:
- EMBO Journal, 1999, v. 18, n. 2, p. 396, doi. 10.1093/emboj/18.2.396
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- Publication type:
- Article
DNA methylation: TET proteins-guardians of CpG islands?
- Published in:
- EMBO Reports, 2012, v. 13, n. 1, p. 28, doi. 10.1038/embor.2011.233
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- Publication type:
- Article
E2F1 is crucial for E2F-dependent apoptosis.
- Published in:
- EMBO Reports, 2005, v. 6, n. 7, p. 661, doi. 10.1038/sj.embor.7400452
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- Publication type:
- Article
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells.
- Published in:
- eLife, 2019, p. 1, doi. 10.7554/eLife.40364
- By:
- Publication type:
- Article
Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 18, p. 1, doi. 10.1093/nar/gkw583
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- Publication type:
- Article
ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 17, p. 8165, doi. 10.1093/nar/gkw505
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- Publication type:
- Article
H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 20, p. 9694, doi. 10.1093/nar/gkv1063
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- Publication type:
- Article
Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 15, p. 7231, doi. 10.1093/nar/gkt528
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- Publication type:
- Article
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.
- Published in:
- Nucleic Acids Research, 2010, v. 38, n. 15, p. 4958, doi. 10.1093/nar/gkq244
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- Publication type:
- Article
TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26093-2
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- Publication type:
- Article
MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23308-4
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- Publication type:
- Article
RIO-kinase 2 is essential for hematopoiesis.
- Published in:
- PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0300623
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- Publication type:
- Article
TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells.
- Published in:
- Stem Cells, 2014, v. 32, n. 8, p. 2084, doi. 10.1002/stem.1718
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- Publication type:
- Article
FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS.
- Published in:
- Nature Medicine, 2014, v. 20, n. 3, p. 272, doi. 10.1038/nm.3485
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- Publication type:
- Article
Author Correction: EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
- Published in:
- EMBO Journal, 2023, v. 42, n. 24, p. 1, doi. 10.15252/embj.2023114221
- By:
- Publication type:
- Article
Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry.
- Published in:
- Nature Genetics, 2002, v. 31, n. 2, p. 190, doi. 10.1038/ng891
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- Publication type:
- Article
Revolution in the Polycomb hierarchy.
- Published in:
- Nature Structural & Molecular Biology, 2014, v. 21, n. 7, p. 573, doi. 10.1038/nsmb.2848
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- Publication type:
- Article
Transcriptional regulation by Polycomb group proteins.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 10, p. 1147, doi. 10.1038/nsmb.2669
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- Publication type:
- Article
Molecular mechanisms and potential functions of histone demethylases.
- Published in:
- Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 5, p. 297, doi. 10.1038/nrm3327
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- Publication type:
- Article
Loss of Geminin induces rereplication in the presence of functional p53.
- Published in:
- Journal of Cell Biology, 2004, v. 165, n. 4, p. 473, doi. 10.1083/jcb.200403106
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- Publication type:
- Article
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.
- Published in:
- Journal of Cell Biology, 2001, v. 155, n. 2, p. 207, doi. 10.1083/jcb.200105137
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- Publication type:
- Article
SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance.
- Published in:
- PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0142806
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- Publication type:
- Article
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer.
- Published in:
- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0096767
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- Publication type:
- Article
The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096545
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- Publication type:
- Article
A Screen Identifies the Oncogenic Micro-RNA miR-378a-5p as a Negative Regulator of Oncogene-Induced Senescence.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091034
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- Publication type:
- Article
Utx Is Required for Proper Induction of Ectoderm and Mesoderm during Differentiation of Embryonic Stem Cells.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060020
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- Publication type:
- Article
A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1.
- Published in:
- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012373
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- Publication type:
- Article
The Polycomb Repressive Complex 2 Is a Potential Target of SUMO Modifications.
- Published in:
- PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002704
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- Publication type:
- Article
The 43rd Annual Meeting of the Canadian College of Neuropsychopharmacology, November 4, 2021.
- Published in:
- 2022
- By:
- Publication type:
- Abstract
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity.
- Published in:
- Molecular Cancer, 2018, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12943-018-0918-6
- By:
- Publication type:
- Article
Middle-down hybrid chromatography/tandem mass spectrometry workflow for characterization of combinatorial post-translational modifications in histones.
- Published in:
- Proteomics, 2014, v. 14, n. 19, p. 2200, doi. 10.1002/pmic.201400084
- By:
- Publication type:
- Article
Author Correction: E2F1 is crucial for E2F-dependent apoptosis.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.73760
- By:
- Publication type:
- Article
Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.
- Published in:
- Oncogene, 2005, v. 24, n. 5, p. 780, doi. 10.1038/sj.onc.1208248
- By:
- Publication type:
- Article
Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.
- Published in:
- EMBO Journal, 2016, v. 35, n. 14, p. 1550, doi. 10.15252/embj.201593317
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- Publication type:
- Article
Jarid1b targets genes regulating development and is involved in neural differentiation.
- Published in:
- EMBO Journal, 2011, v. 30, n. 22, p. 4586, doi. 10.1038/emboj.2011.383
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- Publication type:
- Article
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.
- Published in:
- EMBO Journal, 2007, v. 26, n. 6, p. 1637, doi. 10.1038/sj.emboj.7601632
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- Publication type:
- Article
Cover Feature: Discovery of NSD2‐Degraders from Novel and Selective DEL Hits (ChemBioChem 24/2023).
- Published in:
- ChemBioChem, 2023, v. 24, n. 24, p. 1, doi. 10.1002/cbic.202300750
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- Publication type:
- Article
Discovery of NSD2‐Degraders from Novel and Selective DEL Hits.
- Published in:
- ChemBioChem, 2023, v. 24, n. 24, p. 1, doi. 10.1002/cbic.202300515
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- Publication type:
- Article
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
- Published in:
- Nature, 2011, v. 473, n. 7347, p. 343, doi. 10.1038/nature10066
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- Publication type:
- Article