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In-vitro crystallization of indinavir in the presence of ritonavir and as a function of pH.
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- Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 5, p. 707
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- Article
Prodrugs: design and clinical applications.
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- Nature Reviews Drug Discovery, 2008, v. 7, n. 3, p. 255, doi. 10.1038/nrd2468
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- Article
Current State and Opportunities with Long-acting Injectables: Industry Perspectives from the Innovation and Quality Consortium "Long-Acting Injectables" Working Group.
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- Pharmaceutical Research, 2023, v. 40, n. 7, p. 1601, doi. 10.1007/s11095-022-03391-y
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- Article
Physiologically Based Pharmacokinetics Modeling in Biopharmaceutics: Case Studies for Establishing the Bioequivalence Safe Space for Innovator and Generic Drugs.
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- Pharmaceutical Research, 2023, v. 40, n. 2, p. 337, doi. 10.1007/s11095-022-03319-6
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- Article
Applications, Challenges, and Outlook for PBPK Modeling and Simulation: A Regulatory, Industrial and Academic Perspective.
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- Pharmaceutical Research, 2022, v. 39, n. 8, p. 1701, doi. 10.1007/s11095-022-03274-2
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- Article
Translational Modeling Strategies for Orally Administered Drug Products: Academic, Industrial and Regulatory Perspectives.
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- Pharmaceutical Research, 2020, v. 37, n. 6, p. 1, doi. 10.1007/s11095-020-02814-y
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- Article
Verification of a physiologically based pharmacokinetic model of ritonavir to estimate drug–drug interaction potential of CYP3A4 substrates.
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- Biopharmaceutics & Drug Disposition, 2018, v. 39, n. 3, p. 152, doi. 10.1002/bdd.2122
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- Article
Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability.
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- Biopharmaceutics & Drug Disposition, 2012, v. 33, n. 9, p. 536, doi. 10.1002/bdd.1821
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- Article
Pharmacokinetics of dietary cancer chemopreventive compound dibenzoylmethane in rats and the impact of nanoemulsion and genetic knockout of Nrf2 on its disposition.
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- Biopharmaceutics & Drug Disposition, 2011, v. 32, n. 2, p. 65, doi. 10.1002/bdd.734
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- Article
Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe Space.
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- AAPS Journal, 2024, v. 26, n. 4, p. 1, doi. 10.1208/s12248-024-00938-2
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- Article
Using Mechanistic Modeling Approaches to Support Bioequivalence Assessments for Oral Products.
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- AAPS Journal, 2024, v. 26, n. 1, p. 1, doi. 10.1208/s12248-024-00886-x
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- Article
Applications of Modeling and Simulation Approaches in Support of Drug Product Development of Oral Dosage Forms and Locally Acting Drug Products: a Symposium Summary.
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- AAPS Journal, 2023, v. 25, n. 6, p. 1, doi. 10.1208/s12248-023-00862-x
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- Article
Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis.
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- AAPS Journal, 2023, v. 25, n. 4, p. 1, doi. 10.1208/s12248-023-00822-5
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- Article
Dissolution Profile Similarity Assessment—Best Practices, Decision Trees and Global Harmonization.
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- AAPS Journal, 2023, v. 25, n. 3, p. 1, doi. 10.1208/s12248-023-00795-5
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- Article
Establishing the Safe Space via Physiologically Based Biopharmaceutics Modeling. Case Study: Fevipiprant/QAW039.
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- AAPS Journal, 2023, v. 25, n. 1, p. 1, doi. 10.1208/s12248-023-00787-5
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- Article
An IQ Consortium Perspective on Connecting Dissolution Methods to In Vivo Performance: Analysis of an Industrial Database and Case Studies to Propose a Workflow.
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- AAPS Journal, 2022, v. 24, n. 3, p. 1, doi. 10.1208/s12248-022-00699-w
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- Article
Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
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- 2021
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- Correction Notice
Physiologically Based Pharmacokinetic Modeling of Oral Absorption, pH, and Food Effect in Healthy Volunteers to Drive Alpelisib Formulation Selection.
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- AAPS Journal, 2020, v. 22, n. 6, p. N.PAG, doi. 10.1208/s12248-020-00511-7
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- Article
Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.
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- AAPS Journal, 2020, v. 22, n. 6, p. N.PAG, doi. 10.1208/s12248-020-00508-2
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- Article
Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report.
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- AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0298-x
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- Article
Applications of Clinically Relevant Dissolution Testing: Workshop Summary Report.
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- AAPS Journal, 2018, v. 20, n. 6, p. 1, doi. 10.1208/s12248-018-0252-3
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- Article
Dissolution and Translational Modeling Strategies Enabling Patient-Centric Drug Product Development: the M-CERSI Workshop Summary Report.
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- AAPS Journal, 2018, v. 20, n. 3, p. 1, doi. 10.1208/s12248-018-0213-x
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- Article
Preclinical Pharmacokinetic/Pharmacodynamic Modeling and Simulation in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape.
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- AAPS Journal, 2015, v. 17, n. 2, p. 462, doi. 10.1208/s12248-014-9716-2
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- Article
A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy.
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- AAPS Journal, 2013, v. 15, n. 4, p. 1012, doi. 10.1208/s12248-013-9505-3
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- Article
Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data.
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- AAPS Journal, 2013, v. 15, n. 1, p. 143, doi. 10.1208/s12248-012-9419-5
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- Article
Practical Anticipation of Human Efficacious Doses and Pharmacokinetics Using In Vitro and Preclinical In Vivo Data.
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- AAPS Journal, 2009, v. 11, n. 3, p. 602, doi. 10.1208/s12248-009-9136-x
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- Article
Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective.
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- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 2, p. 297, doi. 10.1002/cpt.2125
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- Article
Ribociclib Drug‐Drug Interactions: Clinical Evaluations and Physiologically‐Based Pharmacokinetic Modeling to Guide Drug Labeling.
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- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 575, doi. 10.1002/cpt.1950
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- Article
Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions.
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- Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1567, doi. 10.1007/s00280-012-1863-5
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- Article
Estimation of fractions metabolized by hepatic CYP enzymes using a concept of inter-system extrapolation factors (ISEFs) - a comparison with the chemical inhibition method.
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- Drug Metabolism & Personalized Therapy, 2017, v. 32, n. 4, p. 191, doi. 10.1515/dmpt-2017-0024
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- Article
Drug-drug interaction (DDI) assessments of ruxolitinib, a dual substrate of CYP3A4 and CYP2C9, using a verified physiologically based pharmacokinetic (PBPK) model to support regulatory submissions.
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- Drug Metabolism & Personalized Therapy, 2019, v. 34, n. 2, p. N.PAG, doi. 10.1515/dmpt-2018-0042
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- Article
Regulatory utility of physiologically‐based pharmacokinetic modeling to support alternative bioequivalence approaches and risk assessment: A workshop summary report.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 5, p. 585, doi. 10.1002/psp4.12907
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- Article
Model‐Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant Patients.
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- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 4, p. 230, doi. 10.1002/psp4.12502
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- Article
Integrated TK-TD modeling for drug-induced concurrent tachycardia and QT changes in beagle dogs.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2017, v. 44, n. 5, p. 449, doi. 10.1007/s10928-017-9532-2
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- Article
Novel Orally Swallowable IntelliCap Device to Quantify Regional Drug Absorption in Human GI Tract Using Diltiazem as Model Drug.
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- AAPS PharmSciTech, 2014, v. 15, n. 6, p. 1490, doi. 10.1208/s12249-014-0172-1
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- Article
Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect.
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- AAPS PharmSciTech, 2014, v. 15, n. 2, p. 400, doi. 10.1208/s12249-014-0075-1
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- Article
Utility of Physiologically Based Modeling and Preclinical In Vitro/ In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound.
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- AAPS PharmSciTech, 2013, v. 14, n. 3, p. 1255, doi. 10.1208/s12249-013-0018-2
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- Article
Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor.
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- Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1533, doi. 10.1002/jcph.1312
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- Article