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Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice.
Published in:
Diabetologia, 2006, v. 49, n. 12, p. 3049, doi. 10.1007/s00125-006-0439-5
By:
- Korsheninnikova, E.;
- Zon, G. C. M.;
- Voshol, P. J.;
- Janssen, G. M.;
- Havekes, L. M.;
- Grefhorst, A.;
- Kuipers, F.;
- Reijngoud, D.-J.;
- Romijn, J. A.;
- Ouwens, D. M.;
- Maassen, J. A.
Publication type:
Article
Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice.
Published in:
Diabetologia, 2006, v. 49, n. 4, p. 732, doi. 10.1007/s00125-006-0138-2
By:
- Heijboer, A. C.;
- van den Hoek, A. M.;
- Parlevliet, E. T.;
- Havekes, L. M.;
- Romijn, J. A.;
- Pijl, H.;
- Corssmit, E. P. M.
Publication type:
Article
Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice.
Published in:
Diabetologia, 2005, v. 48, n. 8, p. 1621, doi. 10.1007/s00125-005-1838-8
By:
- Heijboer, A. C.;
- van den Hoek, A. M.;
- Pijl, H.;
- Voshol, P. J.;
- Havekes, L. M.;
- Romijn, J. A.;
- Corssmit, E. P. M.
Publication type:
Article
Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1.
Published in:
Diabetologia, 2001, v. 44, n. 4, p. 437, doi. 10.1007/s001250051641
By:
- Koopmans, S. J.;
- Jong, M. C.;
- Que, I.;
- Dahlmans, V. E. H.;
- Pijl, H.;
- Radder, J. K.;
- Frölich, M.;
- Havekes, L. M.
Publication type:
Article
Identification of a double mutation in the low-density lipoprotein receptor gene causing familial hypercholesterolemia.
Published in:
Clinical Genetics, 1996, v. 50, n. 6, p. 525, doi. 10.1111/j.1399-0004.1996.tb02727.x
By:
- Lombardi, P.;
- Kamerling, S. W. A.;
- Defesche, J. C.;
- Kastelein, J. J. P.;
- Havekes, L. M.
Publication type:
Article
The effect of dietary phytosphingosine on cholesterol levels and insulin sensitivity in subjects with the metabolic syndrome.
Published in:
European Journal of Clinical Nutrition, 2010, v. 64, n. 4, p. 419, doi. 10.1038/ejcn.2009.154
By:
- Snel, M.;
- Sleddering, M. A.;
- Pijl, H.;
- Nieuwenhuizen, W. F.;
- Frölich, M.;
- Havekes, L. M.;
- Romijn, J. A.;
- Jazet, I. M.
Publication type:
Article
Postprandial triglyceride response in young adult men and familial risk for coronary atherosclerosis.
Published in:
1994
By:
- Uiterwaal, Cuno S. P. M.;
- Grobbee, Diederick E.;
- Witteman, jacqueline C. M.;
- van Stiphout, Willy-Anne H. J.;
- Krauss, Xena H.;
- Havekes, Louis M.;
- de Bruijn, Anthony M.;
- van Pol, Arie;
- Hofman, Albert;
- Uiterwaal, C S;
- Grobbee, D E;
- Witteman, J C;
- van Stiphout, W A;
- Krauss, X H;
- Havekes, L M;
- de Bruijn, A M;
- van Tol, A;
- Hofman, A
Publication type:
journal article
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility.
Published in:
Diabetic Medicine, 2014, v. 31, n. 8, p. 1001, doi. 10.1111/dme.12464
By:
- Guigas, B.;
- Leeuw van Weenen, J. E.;
- Leeuwen, N.;
- Simonis‐Bik, A. M.;
- Haeften, T. W.;
- Nijpels, G.;
- Houwing‐Duistermaat, J. J.;
- Beekman, M.;
- Deelen, J.;
- Havekes, L. M.;
- Penninx, B. W. J. H.;
- Vogelzangs, N.;
- ‘t Riet, E.;
- Dehghan, A.;
- Hofman, A.;
- Witteman, J. C.;
- Uitterlinden, A. G.;
- Grarup, N.;
- Jørgensen, T.;
- Witte, D. R.
Publication type:
Article
APOE* 3Leiden. CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome.
Published in:
Diabetes, Obesity & Metabolism, 2014, v. 16, n. 6, p. 537, doi. 10.1111/dom.12252
By:
- van den Hoek, A. M.;
- van der Hoorn, J. W. A.;
- Maas, A. C.;
- van den Hoogen, R. M.;
- van Nieuwkoop, A.;
- Droog, S.;
- Offerman, E. H.;
- Pieterman, E. J.;
- Havekes, L. M.;
- Princen, H. M. G.
Publication type:
Article
The effect of tibolone on the lipoprotein profile of postmenopausal women with type III hyperlipoproteinemia.
Published in:
2002
By:
- De Beer, F.;
- Smelt, A. H. M.;
- Van Vark, L. C.;
- Hoogerbrugge, N.;
- Havekes, L. M.;
- Gevers Leuven, J. A.
Publication type:
journal article
Leptin Deficiency Per Se Dictates Body Composition and Insulin Action in ob/ ob Mice.
Published in:
Journal of Neuroendocrinology, 2008, v. 20, n. 1, p. 120, doi. 10.1111/j.1365-2826.2007.01626.x
By:
- van den Hoek, A. M.;
- Teusink, B.;
- Voshol, P. J.;
- Havekes, L. M.;
- Romijn, J. A.;
- Pijl, H.
Publication type:
Article
Gut–Brain Axis: Regulation of Glucose Metabolism.
Published in:
Journal of Neuroendocrinology, 2006, v. 18, n. 12, p. 883, doi. 10.1111/j.1365-2826.2006.01492.x
By:
- Heijboer, A. C.;
- Pijl, H.;
- Van den Hoek, A. M.;
- Havekes, L. M.;
- Romijn, J. A.;
- van der Kleij-Corssmit, E. P. M.
Publication type:
Article
Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Published in:
Cell Death & Differentiation, 2006, v. 13, n. 12, p. 2089, doi. 10.1038/sj.cdd.4401973
By:
- Boesten, L S M;
- Zadelaar, S M;
- De Clercq, S;
- Francoz, S;
- van Nieuwkoop, A;
- Biessen, E A L;
- Hofmann, F;
- Feil, S;
- Feil, R;
- Jochemsen, A G;
- Zurcher, C;
- Havekes, L M;
- van Vlijmen, B J M;
- Marine, J-C
Publication type:
Article
Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1.
Published in:
2001
By:
- Jong, Miek C.;
- Voshol, Peter J.;
- Muurling, Martin;
- Dahlmans, Vivian E.H.;
- Romijn, Johannes A.;
- Pijl, Hanno;
- Havekes, Louis M.;
- Jong, M C;
- Voshol, P J;
- Muurling, M;
- Dahlmans, V E;
- Romijn, J A;
- Pijl, H;
- Havekes, L M
Publication type:
journal article
In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake.
Published in:
2001
By:
- Voshol, Peter J.;
- Jong, Miek C.;
- Dahlmans, Vivian E.H.;
- Kratky, Dagmar;
- Levak-Frank, Sanja;
- Zechner, Rudolf;
- Romijn, Johannes A.;
- Havekes, Louis M.;
- Voshol, P J;
- Jong, M C;
- Dahlmans, V E;
- Kratky, D;
- Levak-Frank, S;
- Zechner, R;
- Romijn, J A;
- Havekes, L M
Publication type:
journal article
Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration.
Published in:
British Journal of Pharmacology, 2014, v. 171, n. 4, p. 723, doi. 10.1111/bph.12490
By:
- Wang, Y.;
- Parlevliet, E. T.;
- Geerling, J. J.;
- van der Tuin, S. J. L.;
- Zhang, H.;
- Bieghs, V.;
- Jawad, A. H. M.;
- Shiri-Sverdlov, R.;
- Bot, I.;
- de Jager, S. C. A.;
- Havekes, L. M.;
- Romijn, J. A.;
- van Dijk, K. Willems;
- Rensen, P. C. N.
Publication type:
Article
Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration.
Published in:
British Journal of Pharmacology, 2014, v. 171, n. 3, p. 723, doi. 10.1111/bph.12490
By:
- Wang, Y;
- Parlevliet, E T;
- Geerling, J J;
- Tuin, S J L;
- Zhang, H;
- Bieghs, V;
- Jawad, A H M;
- Shiri ‐ Sverdlov, R;
- Bot, I;
- Jager, S C A;
- Havekes, L M;
- Romijn, J A;
- Willems van Dijk, K;
- Rensen, P C N
Publication type:
Article
The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system.
Published in:
2013
By:
- Coomans, C P;
- Geerling, J J;
- van den Berg, S A A;
- van Diepen, H C;
- Garcia-Tardón, N;
- Thomas, A;
- Schröder-van der Elst, J P;
- Ouwens, D M;
- Pijl, H;
- Rensen, P C N;
- Havekes, L M;
- Guigas, B;
- Romijn, J A
Publication type:
journal article
The insulin sensitizing effect of topiramate involves K<sub>ATP</sub> channel activation in the central nervous system.
Published in:
British Journal of Pharmacology, 2013, v. 170, n. 4, p. 908, doi. 10.1111/bph.12338
By:
- Coomans, C P;
- Geerling, J J;
- Berg, S A A;
- Diepen, H C;
- Garcia ‐ Tardón, N;
- Thomas, A;
- Schröder ‐ van der Elst, J P;
- Ouwens, D M;
- Pijl, H;
- Rensen, P C N;
- Havekes, L M;
- Guigas, B;
- Romijn, J A
Publication type:
Article
The dual PPARalpha/gamma agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice.
Published in:
2009
By:
- van der Hoorn, J. W. A.;
- Jukema, J. W.;
- Havekes, L. M.;
- Lundholm, E.;
- Camejo, G.;
- Rensen, P. C. N.;
- Princen, H. M. G.
Publication type:
journal article
Apolipoprotein E phenotype is not related to late-life depression in a population-based sample.
Published in:
1998
By:
- Schmand, B.;
- Hooijer, C.;
- Jonker, C.;
- Lindeboom, J.;
- Havekes, L. M.
Publication type:
journal article

Found: 21