Found: 14
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Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 7, p. 1922, doi. 10.3390/pharmaceutics15071922
- By:
- Publication type:
- Article
Quantitative ADME Proteomics - CYP and UGT Enzymes in the Beagle Dog Liver and Intestine.
- Published in:
- Pharmaceutical Research, 2015, v. 32, n. 1, p. 74, doi. 10.1007/s11095-014-1446-8
- By:
- Publication type:
- Article
Development of a Korean‐specific virtual population for physiologically based pharmacokinetic modelling and simulation.
- Published in:
- Biopharmaceutics & Drug Disposition, 2019, v. 40, n. 3/4, p. 135, doi. 10.1002/bdd.2178
- By:
- Publication type:
- Article
Optimization of intestinal microsomal preparation in the rat: A systematic approach to assess the influence of various methodologies on metabolic activity and scaling factors.
- Published in:
- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 3, p. 187, doi. 10.1002/bdd.2070
- By:
- Publication type:
- Article
Quantifying gut wall metabolism: methodology matters.
- Published in:
- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 2, p. 155, doi. 10.1002/bdd.2062
- By:
- Publication type:
- Article
Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations.
- Published in:
- AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0309-y
- By:
- Publication type:
- Article
Towards Bridging Translational Gap in Cardiotoxicity Prediction: an Application of Progressive Cardiac Risk Assessment Strategy in TdP Risk Assessment of Moxifloxacin.
- Published in:
- AAPS Journal, 2018, v. 20, n. 3, p. 1, doi. 10.1208/s12248-018-0199-4
- By:
- Publication type:
- Article
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.
- Published in:
- AAPS Journal, 2016, v. 18, n. 3, p. 589, doi. 10.1208/s12248-016-9889-y
- By:
- Publication type:
- Article
Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2021, v. 87, n. 7, p. 2711, doi. 10.1111/bcp.14609
- By:
- Publication type:
- Article
Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 6, p. 1264, doi. 10.1002/cpt.3032
- By:
- Publication type:
- Article
Prediction of CYP‐mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 7, p. 822, doi. 10.1002/psp4.12794
- By:
- Publication type:
- Article
Development of physiologically‐based pharmacokinetic models for standard of care and newer tuberculosis drugs.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 11, p. 1382, doi. 10.1002/psp4.12707
- By:
- Publication type:
- Article
The Use of ROC Analysis for the Qualitative Prediction of Human Oral Bioavailability from Animal Data.
- Published in:
- Pharmaceutical Research, 2014, v. 31, n. 3, p. 720, doi. 10.1007/s11095-013-1193-2
- By:
- Publication type:
- Article