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Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.
Published in:
Angewandte Chemie, 2017, v. 129, n. 49, p. 15761, doi. 10.1002/ange.201706788
By:
- Gerken, Philip A.;
- Wolstenhulme, Jamie R.;
- Tumber, Anthony;
- Hatch, Stephanie B.;
- Zhang, Yijia;
- Müller, Susanne;
- Chandler, Shane A.;
- Mair, Barbara;
- Li, Fengling;
- Nijman, Sebastian M. B.;
- Konietzny, Rebecca;
- Szommer, Tamas;
- Yapp, Clarence;
- Fedorov, Oleg;
- Benesch, Justin L. P.;
- Vedadi, Masoud;
- Kessler, Benedikt M.;
- Kawamura, Akane;
- Brennan, Paul E.;
- Smith, Martin D.
Publication type:
Article
SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020.
Published in:
Eurosurveillance (15607917), 2020, v. 25, n. 42, p. 18, doi. 10.2807/1560-7917.es.2020.25.41.2001721
By:
- Lumley, Sheila F.;
- Eyre, David W.;
- McNaughton, Anna L.;
- Howarth, Alison;
- Hoosdally, Sarah;
- Hatch, Stephanie B.;
- Kavanagh, James;
- Chau, Kevin K.;
- Downs, Louise O.;
- Cox, Stuart;
- Dunn, Laura;
- Justice, Anita;
- Wareing, Susan;
- Dingle, Kate;
- Rudkin, Justine;
- Auckland, Kathryn;
- Fyfe, Alexander;
- Bolton, Jai;
- Paton, Robert;
- Mentzer, Alexander J.
Publication type:
Article
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.
Published in:
Angewandte Chemie International Edition, 2017, v. 56, n. 49, p. 15555, doi. 10.1002/anie.201706788
By:
- Gerken, Philip A.;
- Wolstenhulme, Jamie R.;
- Tumber, Anthony;
- Hatch, Stephanie B.;
- Zhang, Yijia;
- Müller, Susanne;
- Chandler, Shane A.;
- Mair, Barbara;
- Li, Fengling;
- Nijman, Sebastian M. B.;
- Konietzny, Rebecca;
- Szommer, Tamas;
- Yapp, Clarence;
- Fedorov, Oleg;
- Benesch, Justin L. P.;
- Vedadi, Masoud;
- Kessler, Benedikt M.;
- Kawamura, Akane;
- Brennan, Paul E.;
- Smith, Martin D.
Publication type:
Article
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 566, doi. 10.3390/ijms22020566
By:
- Wells, Carrow I.;
- Al-Ali, Hassan;
- Andrews, David M.;
- Asquith, Christopher R. M.;
- Axtman, Alison D.;
- Dikic, Ivan;
- Ebner, Daniel;
- Ettmayer, Peter;
- Fischer, Christian;
- Frederiksen, Mathias;
- Futrell, Robert E.;
- Gray, Nathanael S.;
- Hatch, Stephanie B.;
- Knapp, Stefan;
- Lücking, Ulrich;
- Michaelides, Michael;
- Mills, Caitlin E.;
- Müller, Susanne;
- Owen, Dafydd;
- Picado, Alfredo
Publication type:
Article
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.60675
By:
- Eyre, David W.;
- Lumley, Sheila F.;
- O'Donnell, Denise;
- Campbell, Mark;
- Sims, Elizabeth;
- Lawson, Elaine;
- Warren, Fiona;
- James, Tim;
- Cox, Stuart;
- Howarth, Alison;
- Doherty, George;
- Hatch, Stephanie B.;
- Kavanagh, James;
- Chau, Kevin K.;
- Fowler, Philip W.;
- Swann, Jeremy;
- Volk, Denis;
- Fan Yang-Turner;
- Stoesser, Nicole;
- Matthews, Philippa C.
Publication type:
Article
E2F1 proteolysis via SCF‐cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.
Published in:
EMBO Journal, 2019, v. 38, n. 20, p. 1, doi. 10.15252/embj.2018101443
By:
- Burdova, Kamila;
- Yang, Hongbin;
- Faedda, Roberta;
- Hume, Samuel;
- Chauhan, Jagat;
- Ebner, Daniel;
- Kessler, Benedikt M;
- Vendrell, Iolanda;
- Drewry, David H;
- Wells, Carrow I;
- Hatch, Stephanie B;
- Dianov, Grigory L;
- Buffa, Francesca M;
- D'Angiolella, Vincenzo
Publication type:
Article
DNA damage responses protect xeroderma pigmentosum variant from UVC-induced clastogenesis.
Published in:
Carcinogenesis, 2002, v. 23, n. 6, p. 959, doi. 10.1093/carcin/23.6.959
By:
- Cordeiro-Stone, Marila;
- Frank, Alexandra;
- Bryant, Miriam;
- Oguejiofor, Ikechukwu;
- Hatch, Stephanie B.;
- McDaniel, Lisa D.;
- Kaufmann, William K.
Publication type:
Article
Assessing histone demethylase inhibitors in cells: lessons learned.
Published in:
Epigenetics & Chromatin, 2017, v. 10, p. 1, doi. 10.1186/s13072-017-0116-6
By:
- Hatch, Stephanie B.;
- Yapp, Clarence;
- Montenegro, Raquel C.;
- Savitsky, Pavel;
- Gamble, Vicki;
- Tumber, Anthony;
- Ruda, Gian Filippo;
- Bavetsias, Vassilios;
- Fedorov, Oleg;
- Atrash, Butrus;
- Raynaud, Florence;
- Lanigan, Rachel;
- Carmichael, LeAnne;
- Tomlin, Kathy;
- Burke, Rosemary;
- Westaway, Susan M.;
- Brown, Jack A.;
- Prinjha, Rab K.;
- Martinez, Elisabeth D.;
- Oppermann, Udo
Publication type:
Article
Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugs.
Published in:
2021
By:
- Arnaiz, Esther;
- Miar, Ana;
- Bridges, Esther;
- Prasad, Naveen;
- Hatch, Stephanie B.;
- Ebner, Daniel;
- Lawrie, Charles H.;
- Harris, Adrian L.
Publication type:
journal article
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Published in:
Carcinogenesis, 2012, v. 33, n. 11, p. 2026, doi. 10.1093/carcin/bgs239
By:
- Nicolay, Nils H.;
- Carter, Rebecca;
- Hatch, Stephanie B.;
- Schultz, Niklas;
- Prevo, Remko;
- McKenna, W. Gillies;
- Helleday, Thomas;
- Sharma, Ricky A.
Publication type:
Article
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Published in:
Nature Communications, 2017, v. 8, n. 4, p. 14773, doi. 10.1038/ncomms14773
By:
- Kawamura, Akane;
- Münzel, Martin;
- Kojima, Tatsuya;
- Yapp, Clarence;
- Bhushan, Bhaskar;
- Goto, Yuki;
- Tumber, Anthony;
- Katoh, Takayuki;
- King, Oliver N. F.;
- Passioura, Toby;
- Walport, Louise J.;
- Hatch, Stephanie B.;
- Madden, Sarah;
- Müller, Susanne;
- Brennan, Paul E.;
- Chowdhury, Rasheduzzaman;
- Hopkinson, Richard J.;
- Suga, Hiroaki;
- Schofield, Christopher J.
Publication type:
Article
Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status.
Published in:
Clinical Infectious Diseases, 2022, v. 74, n. 7, p. 1208, doi. 10.1093/cid/ciab608
By:
- Lumley, Sheila F;
- Rodger, Gillian;
- Constantinides, Bede;
- Sanderson, Nicholas;
- Chau, Kevin K;
- Street, Teresa L;
- O'Donnell, Denise;
- Howarth, Alison;
- Hatch, Stephanie B;
- Marsden, Brian D;
- Cox, Stuart;
- James, Tim;
- Warren, Fiona;
- Peck, Liam J;
- Ritter, Thomas G;
- Toledo, Zoe de;
- Warren, Laura;
- Axten, David;
- Cornall, Richard J;
- Jones, E Yvonne
Publication type:
Article
The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 3, p. e699, doi. 10.1093/cid/ciab004
By:
- Lumley, Sheila F;
- Wei, Jia;
- O'Donnell, Denise;
- Stoesser, Nicole E;
- Matthews, Philippa C;
- Howarth, Alison;
- Hatch, Stephanie B;
- Marsden, Brian D;
- Cox, Stuart;
- James, Tim;
- Peck, Liam J;
- Ritter, Thomas G;
- Toledo, Zoe de;
- Cornall, Richard J;
- Jones, E Yvonne;
- Stuart, David I;
- Screaton, Gavin;
- Ebner, Daniel;
- Hoosdally, Sarah;
- Crook, Derrick W
Publication type:
Article
XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: Suitability as a biomarker for patient selection.
Published in:
International Journal of Cancer, 2014, v. 134, n. 6, p. 1495, doi. 10.1002/ijc.28454
By:
- Hatch, Stephanie B.;
- Swift, Lonnie P.;
- Caporali, Simona;
- Carter, Rebecca;
- Hill, Esme J.;
- MacGregor, Thomas P.;
- D'Atri, Stefania;
- Middleton, Mark R.;
- McHugh, Peter J.;
- Sharma, Ricky A.
Publication type:
Article
Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Published in:
2021
By:
- Eyre, David W.;
- Lumley, Sheila F.;
- O'Donnell, Denise;
- Stoesser, Nicole E.;
- Matthews, Philippa C.;
- Howarth, Alison;
- Hatch, Stephanie B.;
- Marsden, Brian D.;
- Cox, Stuart;
- James, Tim;
- Cornall, Richard J.;
- Stuart, David I.;
- Screaton, Gavin;
- Ebner, Daniel;
- Crook, Derrick W.;
- Conlon, Christopher P.;
- Jeffery, Katie;
- Walker, Timothy M.;
- Peto, Timothy E. A.
Publication type:
journal article
Sequence dependent instability of mononucleotide microsatellites in cultured mismatch repair proficient and deficient mammalian cells.
Published in:
Human Molecular Genetics, 2002, v. 11, n. 6, p. 707, doi. 10.1093/hmg/11.6.707
By:
- Boyer, Jayne C.;
- Yamada, Nazumi A.;
- Roques, C. Natalia;
- Hatch, Stephanie B.;
- Riess, Kevin;
- Farber, Rosann A.
Publication type:
Article

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