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Synthesis of enantiomerically pure [<sup>14</sup>C]-labelled morpholine derivatives for a class of trace amine-associate receptor 1 agonists.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2016, v. 59, n. 14, p. 635, doi. 10.1002/jlcr.3403
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- Publication type:
- Article
Radiosynthesis of [5-[<sup>11</sup>C]methanesulfonyl-2-(( S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindol-2-yl]-methanone ([<sup>11</sup>C]RO5013853), a novel PET tracer for the glycine transporter type I (GlyT1)
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2011, v. 54, n. 11, p. 702, doi. 10.1002/jlcr.1911
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- Publication type:
- Article
15th Workshop of the International Isotope Society-Central European Division: The synthesis and applications of isotopes and isotopically labelled compounds Bad Soden, Germany, June 12-13, 2008.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2009, v. 52, n. 7, p. 253, doi. 10.1002/jlcr.1594
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- Publication type:
- Article
Synthesis of [<sup>3</sup>H]fenobam, a radioligand for the mGlu5 receptor.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2008, v. 51, n. 1, p. 77, doi. 10.1002/jlcr.1470
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- Publication type:
- Article
Brain organoids and organoid intelligence from ethical, legal, and social points of view.
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- Frontiers in Artificial Intelligence, 2024, p. 1, doi. 10.3389/frai.2023.1307613
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- Publication type:
- Article
Eine wirklich humane Bestimmung von Endotoxinen und Nicht-Endotoxin-Pyrogenen.
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- Pharmazeutische Industrie (Pharmind), 2013, v. 75, n. 5, p. 825
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- Publication type:
- Article
Absolute Bioavailability of Vemurafenib in Patients With BRAF<sup>V600</sup> Mutation–Positive Malignancies.
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- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 4, p. 496, doi. 10.1002/cpdd.773
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- Publication type:
- Article
A human-derived 3D brain organoid model to study JC virus infection.
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- Journal of NeuroVirology, 2022, v. 28, n. 1, p. 17, doi. 10.1007/s13365-022-01062-7
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- Publication type:
- Article
Deconvoluting gene and environment interactions to develop an "epigenetic score meter" of disease.
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- EMBO Molecular Medicine, 2023, v. 15, n. 9, p. 1, doi. 10.15252/emmm.202318208
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- Publication type:
- Article
Non-Animal Models: Complexity for Interactions... Connecting Science.
- Published in:
- Altex, 2024, v. 41, n. 4, p. 666, doi. 10.14573/altex.2407181
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- Publication type:
- Article
E-validation - Unleashing AI for Validation.
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- Altex, 2024, v. 41, n. 4, p. 567, doi. 10.14573/altex.2409211
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- Publication type:
- Article
Leveraging Biomarkers and Translational Medicine for Preclinical Safety - Lessons for Advancing the Validation of Alternatives to Animal Testing.
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- Altex, 2024, v. 41, n. 4, p. 545, doi. 10.14573/altex.2410011
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- Publication type:
- Article
The Validation of Regulatory Test Methods - Conceptual, Ethical, and Philosophical Foundations.
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- Altex, 2024, v. 41, n. 4, p. 525, doi. 10.14573/altex.2409271
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- Publication type:
- Article
The Implementation Moonshot Project for Alternative Chemical Testing (IMPACT) toward a Human Exposome Project.
- Published in:
- Altex, 2024, v. 41, n. 3, p. 344, doi. 10.14573/altex.2407081
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- Publication type:
- Article
Trust Your Gut: Establishing Confidence in Gastrointestinal Models - An Overview of the State of the Science and Contexts of Use.
- Published in:
- Altex, 2024, v. 41, n. 3, p. 402, doi. 10.14573/altex.2403261
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- Publication type:
- Article
Human IPSC-Derived Model to Study Myelin Disruption.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9473, doi. 10.3390/ijms22179473
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- Publication type:
- Article
Human Oligodendrocytes and Myelin In Vitro to Evaluate Developmental Neurotoxicity.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 7929, doi. 10.3390/ijms22157929
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- Publication type:
- Article
Induction of blood-brain barrier properties in cultured brain capillary endothelial cells: Comparison between primary glial cells and C6 cell line.
- Published in:
- Glia, 2005, v. 51, n. 3, p. 187, doi. 10.1002/glia.20189
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- Publication type:
- Article
Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology.
- Published in:
- Archives of Toxicology, 2024, v. 98, n. 8, p. 2299, doi. 10.1007/s00204-024-03802-6
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- Publication type:
- Article
Artificial intelligence (AI)—it's the end of the tox as we know it (and I feel fine).
- Published in:
- Archives of Toxicology, 2024, v. 98, n. 3, p. 735, doi. 10.1007/s00204-023-03666-2
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- Publication type:
- Article
G × E interactions as a basis for toxicological uncertainty.
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- Archives of Toxicology, 2023, v. 97, n. 7, p. 2035, doi. 10.1007/s00204-023-03500-9
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- Publication type:
- Article
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi.
- Published in:
- Archives of Toxicology, 2022, v. 96, n. 7, p. 1935, doi. 10.1007/s00204-022-03299-x
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- Publication type:
- Article
Characterisation of Cadmium Chloride Induced Molecular and Functional Alterations in Airway Epithelial Cells.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2010, v. 25, n. 1, p. 159, doi. 10.1159/000272060
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- Publication type:
- Article
REPLACING ANIMAL TESTING: HOW AND WHEN?
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- Frontiers for Young Minds, 2023, p. 1, doi. 10.3389/frym.2022.959496
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- Publication type:
- Article
The (misleading) role of animal models in drug development.
- Published in:
- Frontiers in Drug Discovery, 2024, p. 1, doi. 10.3389/fddsv.2024.1355044
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- Publication type:
- Article
Metabolomics in Preclinical Drug Safety Assessment: Current Status and Future Trends.
- Published in:
- Metabolites (2218-1989), 2024, v. 14, n. 2, p. 98, doi. 10.3390/metabo14020098
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- Publication type:
- Article
Challenges and Scientific Prospects of the Newest Generation of mRNA-Based Vaccines against SARS-CoV-2.
- Published in:
- Life (2075-1729), 2021, v. 11, n. 9, p. 907, doi. 10.3390/life11090907
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- Publication type:
- Article
A new mechanism for IL-5-dependent helminth control: neutrophil accumulation and neutrophil-mediated worm encapsulation in murine filariasis are abolished in the absence of IL-5.
- Published in:
- International Immunology, 2000, v. 12, n. 6, p. 899, doi. 10.1093/intimm/12.6.899
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- Publication type:
- Article
Toward a 3D model of human brain development for studying gene/environment interactions.
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- Stem Cell Research & Therapy, 2013, v. 4, p. 1, doi. 10.1186/scrt365
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- Publication type:
- Article
Outcome Prediction by Traditional and New Markers of Inflammation in Patients with Sepsis.
- Published in:
- Clinical Chemistry & Laboratory Medicine, 1999, v. 37, n. 3, p. 363
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- Publication type:
- Article
COVID-19 vaccines: ethical framework concerning human challenge studies.
- Published in:
- DARU: Journal of Pharmaceutical Sciences, 2020, v. 28, p. 1, doi. 10.1007/s40199-020-00371-8
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- Publication type:
- Article
Copulatory Behavior and the Initiation of Pregnancy in California Voles (Microtus californicus).
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- Brain, Behavior & Evolution, 1979, v. 16, n. 3, p. 176, doi. 10.1159/000121835
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- Publication type:
- Article
Activation of Neutrophils and Inhibition of the Proinflammatory Cytokine Response by Endogenous Granulocyte Colony-Stimulating Factor in Murine Pneumococcal Pneumonia.
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- Journal of Infectious Diseases, 2004, v. 189, n. 8, p. 1506, doi. 10.1086/382962
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- Publication type:
- Article
Severe Hepatitis E Virus Infection after Ingestion of Uncooked Liver from a Wild Boar.
- Published in:
- 2003
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- Publication type:
- Letter
Heterozygous Toll-Like Receptor 4 Polymorphism Does Not Influence Lipopolysaccharide-Induced Cytokine Release in Human Whole Blood.
- Published in:
- Journal of Infectious Diseases, 2003, v. 188, n. 6, p. 938, doi. 10.1086/378095
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- Publication type:
- Article
Anti--Tumor Necrosis Factor Antibody Impairs the Therapeutic Effect of Ceftriaxone in Murine Pneumococcal Pneumonia.
- Published in:
- Journal of Infectious Diseases, 2003, v. 188, n. 2, p. 282, doi. 10.1086/376454
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- Publication type:
- Article
Characteristics of Surfactant Protein A and D Binding to Lipoteichoic Acid and Peptidoglycan, 2 Major Cell Wall Components of Gram-Positive Bacteria.
- Published in:
- Journal of Infectious Diseases, 2001, v. 184, n. 9, p. 1143, doi. 10.1086/323746
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- Publication type:
- Article
Filgrastim Restores Interleukin-2 Production in Blood from Patients with Advanced Human Immunodeficiency Virus Infection.
- Published in:
- Journal of Infectious Diseases, 1998, v. 178, n. 3, p. 686, doi. 10.1086/515338
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- Publication type:
- Article
Control of Fecal Peritoneal Infection in Mice by Colony-Stimulating Factors.
- Published in:
- Journal of Infectious Diseases, 1996, v. 174, n. 4, p. 790, doi. 10.1093/infdis/174.4.790
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- Publication type:
- Article
Distribution of BACE1 in the rodent, monkey and human brain
- Published in:
- 2012
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- Publication type:
- Abstract
The new revolution in toxicology: The good, the bad, and the ugly.
- Published in:
- Annals of the New York Academy of Sciences, 2013, v. 1278, n. 1, p. 11, doi. 10.1111/nyas.12086
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- Publication type:
- Article
Moving from CFC Aerosol to HFA Aerosol or Dry Powder Inhalers: What Do Patients Think?
- Published in:
- Respiration, 2002, v. 69, n. 4, p. 314, doi. 10.1159/000063276
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- Publication type:
- Article
Induction of IL‐10‐balanced immune profiles following exposure to LTA from <italic>Staphylococcus epidermidis</italic>.
- Published in:
- Experimental Dermatology, 2018, v. 27, n. 4, p. 318, doi. 10.1111/exd.13540
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- Publication type:
- Article
Erratum: Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function.
- Published in:
- Scientific Reports, 2016, p. 33011, doi. 10.1038/srep33011
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- Publication type:
- Article
Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function.
- Published in:
- Scientific Reports, 2016, p. 28994, doi. 10.1038/srep28994
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- Publication type:
- Article
Green Toxicology: a strategy for sustainable chemical and material development.
- Published in:
- 2017
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- Publication type:
- Editorial
Metabolomics Reveals Metabolic Alterations by Intrauterine Growth Restriction in the Fetal Rabbit Brain
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064545
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- Publication type:
- Article
Effect of filgrastim treatment on inflammatory cytokines and lymphocyte functions<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1999, v. 66, n. 4, p. 415, doi. 10.1053/cp.1999.v66.a101210
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- Publication type:
- Article
Comparison of the Interleukin-1β-Inducing Potency of Allergenic Spores from Higher Fungi (Basidiomycetes) in a Cryopreserved Human Whole Blood System.
- Published in:
- International Archives of Allergy & Immunology, 2014, v. 163, n. 2, p. 154, doi. 10.1159/000357036
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- Publication type:
- Article
The Exposome Applied: A Step toward Defining the Totality of Environmental Exposures in Asthma.
- Published in:
- 2022
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- Publication type:
- Editorial