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Physical Activity Producing Low, but Not Medium or Higher, Vertical Impacts Is Inversely Related to BMI in Older Adults: Findings From a Multicohort Study.
Published in:
2018
By:
- Elhakeem, Ahmed;
- Hannam, Kimberly;
- Deere, Kevin C.;
- Hartley, April;
- Clark, Emma M.;
- Moss, Charlotte;
- Edwards, Mark H.;
- Dennison, Elaine;
- Gaysin, Tim;
- Kuh, Diana;
- Wong, Andrew;
- Cooper, Cyrus;
- Cooper, Rachel;
- Tobias, Jon H.
Publication type:
journal article
Sarcopenia Is Negatively Related to High Gravitational Impacts Achieved From Day-to-day Physical Activity.
Published in:
2018
By:
- Hartley, April;
- Gregson, Celia L.;
- Hannam, Kimberly;
- Deere, Kevin C.;
- Clark, Emma M.;
- Tobias, Jon H.
Publication type:
journal article
Characterization of Vertical Accelerations Experienced by Older People Attending an Aerobics Class Designed to Produce High Impacts.
Published in:
Journal of Aging & Physical Activity, 2016, v. 24, n. 2, p. 268, doi. 10.1123/japa.2015-0060
By:
- Hannam, Kimberly;
- Deere, Kevin;
- Worrall, Sue;
- Hartley, April;
- Tobias, Jon H.
Publication type:
Article
Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study.
Published in:
European Journal of Epidemiology, 2023, v. 38, n. 7, p. 795, doi. 10.1007/s10654-023-00986-6
By:
- Power, Grace Marion;
- Tobias, Jonathan H;
- Frayling, Timothy M;
- Tyrrell, Jessica;
- Hartley, April E;
- Heron, Jon E;
- Davey Smith, George;
- Richardson, Tom G
Publication type:
Article
Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.
Published in:
Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-020-02207-9
By:
- Cousminer, Diana L.;
- Wagley, Yadav;
- Pippin, James A.;
- Elhakeem, Ahmed;
- Way, Gregory P.;
- Pahl, Matthew C.;
- McCormack, Shana E.;
- Chesi, Alessandra;
- Mitchell, Jonathan A.;
- Kindler, Joseph M.;
- Baird, Denis;
- Hartley, April;
- Howe, Laura;
- Kalkwarf, Heidi J.;
- Lappe, Joan M.;
- Lu, Sumei;
- Leonard, Michelle E.;
- Johnson, Matthew E.;
- Hakonarson, Hakon;
- Gilsanz, Vicente
Publication type:
Article
Correlates of high-impact physical activity measured objectively in older British adults.
Published in:
Journal of Public Health, 2018, v. 40, n. 4, p. 727, doi. 10.1093/pubmed/fdx171
By:
- Elhakeem, Ahmed;
- Hannam, Kimberly;
- Deere, Kevin C;
- Hartley, April;
- Clark, Emma M;
- Moss, Charlotte;
- Edwards, Mark H;
- Dennison, Elaine;
- Gaysin, Tim;
- Kuh, Diana;
- Wong, Andrew;
- Fox, Kenneth R;
- Cooper, Cyrus;
- Cooper, Rachel;
- Tobias, Jon H
Publication type:
Article
Mendelian randomization provides evidence for a causal effect of higher serum IGF-1 concentration on risk of hip and knee osteoarthritis.
Published in:
Rheumatology, 2021, v. 60, n. 4, p. 1676, doi. 10.1093/rheumatology/keaa597
By:
- Hartley, April;
- Sanderson, Eleanor;
- Paternoster, Lavinia;
- Teumer, Alexander;
- Kaplan, Robert C;
- Tobias, Jon H;
- Gregson, Celia L
Publication type:
Article
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
Published in:
2022
By:
- Hartley, April;
- Sanderson, Eleanor;
- Granell, Raquel;
- Paternoster, Lavinia;
- Zheng, Jie;
- Smith, George Davey;
- Southam, Lorraine;
- Hatzikotoulas, Konstantinos;
- Boer, Cindy G;
- Meurs, Joyce van;
- Zeggini, Eleftheria;
- Consortium, The Genetics of Osteoarthritis;
- Gregson, Celia L;
- Tobias, Jon H;
- van Meurs, Joyce;
- Genetics of Osteoarthritis Consortium
Publication type:
journal article
Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-020-02371-0
By:
- Hartley, April;
- Hardcastle, Sarah A.;
- Frysz, Monika;
- Parkinson, Jon;
- Paternoster, Lavinia;
- McCloskey, Eugene;
- Poole, Kenneth E. S.;
- Javaid, Muhammad K.;
- Aye, Mo;
- Moss, Katie;
- Williams, Martin;
- Tobias, Jon H.;
- Gregson, Celia L.
Publication type:
Article
A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis.
Published in:
Journal of Bone & Mineral Research, 2020, v. 35, n. 1, p. 92, doi. 10.1002/jbmr.3875
By:
- Gregson, Celia L;
- Bergen, Dylan J. M.;
- Leo, Paul;
- Sessions, Richard B;
- Wheeler, Lawrie;
- Hartley, April;
- Youlten, Scott;
- Croucher, Peter I;
- McInerney‐Leo, Aideen M;
- Fraser, William;
- Tang, Jonathan CY;
- Anderson, Lisa;
- Marshall, Mhairi;
- Sergot, Leon;
- Paternoster, Lavinia;
- Davey Smith, George;
- Brown, Matthew A;
- Hammond, Chrissy;
- Kemp, John P;
- Tobias, Jon H
Publication type:
Article
Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression.
Published in:
PLoS Genetics, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pgen.1010596
By:
- Mitchell, Ruth E.;
- Hartley, April E.;
- Walker, Venexia M.;
- Gkatzionis, Apostolos;
- Yarmolinsky, James;
- Bell, Joshua A.;
- Chong, Amanda H. W.;
- Paternoster, Lavinia;
- Tilling, Kate;
- Smith, George Davey
Publication type:
Article
Adjusting for collider bias in genetic association studies using instrumental variable methods.
Published in:
Genetic Epidemiology, 2022, v. 46, n. 5/6, p. 303, doi. 10.1002/gepi.22455
By:
- Cai, Siyang;
- Hartley, April;
- Mahmoud, Osama;
- Tilling, Kate;
- Dudbridge, Frank
Publication type:
Article
A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field.
Published in:
JBMR Plus, 2022, v. 6, n. 10, p. 1, doi. 10.1002/jbm4.10675
By:
- Hartley, April E;
- Power, Grace M;
- Sanderson, Eleanor;
- Smith, George Davey
Publication type:
Article
A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field.
Published in:
JBMR Plus, 2022, v. 6, n. 10, p. 1, doi. 10.1002/jbm4.10675
By:
- Hartley, April E;
- Power, Grace M;
- Sanderson, Eleanor;
- Smith, George Davey
Publication type:
Article
Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization.
Published in:
Arthritis & Rheumatology, 2023, v. 75, n. 10, p. 1781, doi. 10.1002/art.42538
By:
- Zheng, Jie;
- Wheeler, Eleanor;
- Pietzner, Maik;
- Andlauer, Till F. M.;
- Yau, Michelle S.;
- Hartley, April E.;
- Brumpton, Ben Michael;
- Rasheed, Humaira;
- Kemp, John P.;
- Frysz, Monika;
- Robinson, Jamie;
- Reppe, Sjur;
- Prijatelj, Vid;
- Gautvik, Kaare M.;
- Falk, Louise;
- Maerz, Winfried;
- Gergei, Ingrid;
- Peyser, Patricia A.;
- Kavousi, Maryam;
- de Vries, Paul S.
Publication type:
Article
A Genome‐Wide Association Study Meta‐Analysis of Alpha Angle Suggests Cam‐Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults.
Published in:
Arthritis & Rheumatology, 2023, v. 75, n. 6, p. 900, doi. 10.1002/art.42451
By:
- Faber, Benjamin G.;
- Frysz, Monika;
- Hartley, April E.;
- Ebsim, Raja;
- Boer, Cindy G.;
- Saunders, Fiona R.;
- Gregory, Jennifer S.;
- Aspden, Richard M.;
- Harvey, Nicholas C.;
- Southam, Lorraine;
- Giles, William;
- Le Maitre, Christine L.;
- Wilkinson, J. Mark;
- van Meurs, Joyce B. J.;
- Zeggini, Eleftheria;
- Cootes, Timothy;
- Lindner, Claudia;
- Kemp, John P.;
- Davey Smith, George;
- Tobias, Jonathan H.
Publication type:
Article
Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.
Published in:
Clinical Endocrinology, 2020, v. 92, n. 1, p. 29, doi. 10.1111/cen.14119
By:
- Hartley, April;
- Paternoster, Lavinia;
- Evans, David M.;
- Fraser, William D.;
- Tang, Jonathan;
- Lawlor, Debbie A.;
- Tobias, Jon H.;
- Gregson, Celia L.
Publication type:
Article

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