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Targeting ER stress--induced autophagy overcomes BRAF inhibitor resistance in melanoma.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 3, p. 1406, doi. 10.1172/JCI70454
By:
- Xiao-Hong Ma;
- Sheng-Fu Piao;
- Dey, Souvik;
- Mcafee, Quentin;
- Karakousis, Giorgos;
- Villanueva, Jessie;
- Hart, Lori S.;
- Levi, Samuel;
- Hu, Janice;
- Gao Zhang;
- Lazova, Rossitza;
- Klump, Vincent;
- Pawelek, John M.;
- Xiaowei Xu;
- Wei Xu;
- Schuchter, Lynn M.;
- Davies, Michael A.;
- Herlyn, Meenhard;
- Winkler, Jeffrey;
- Koumenis, Constantinos
Publication type:
Article
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 4621, doi. 10.1172/JCI62973
By:
- Hart, Lori S.;
- Cunningham, John T.;
- Datta, Tatini;
- Dey, Souvik;
- Tameire, Feven;
- Lehman, Stacey L.;
- Bo Qiu;
- Haiyan Zhang;
- Cerniglia, George;
- Meixia Bi;
- Yan Li;
- Yan Gao;
- Huayi Liu;
- Changhong Li;
- Maity, Amit;
- Thomas-Tikhonenko, Andrei;
- Perl, Alexander E.;
- Albert Koong;
- Fuchs, Serge Y.;
- Diehl, J. Alan
Publication type:
Article
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
Published in:
Nature Genetics, 2015, v. 47, n. 8, p. 864, doi. 10.1038/ng.3333
By:
- Eleveld, Thomas F;
- Koster, Jan;
- Schild, Linda;
- Zwijnenburg, Danny A;
- Ebus, Marli E;
- van Sluis, Peter;
- Hakkert, Anne;
- Westerhout, Ellen M;
- Dolman, M Emmy M;
- Versteeg, Rogier;
- Molenaar, Jan J;
- Hart, Lori S;
- Rader, JulieAnn;
- Wei, Jun S;
- Zhang, Shile;
- Khan, Javed;
- Naranjo, Arlene;
- Gastier-Foster, Julie M;
- Asgharzadeh, Shahab;
- Smith, Malcolm A
Publication type:
Article
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.
Published in:
EMBO Journal, 2010, v. 29, n. 12, p. 2082, doi. 10.1038/emboj.2010.81
By:
- Jiangbin Ye;
- Kumanova, Monika;
- Hart, Lori S.;
- Sloane, Kelly;
- Haiyan Zhang;
- De Panis, Diego N.;
- Bobrovnikova-Marjon, Ekaterina;
- Diehl, J. Alan;
- Ron, David;
- Koumenis, Constantinos
Publication type:
Article
Off-Target Lapatinib Activity Sensitizes Colon Cancer Cells Through TRAIL Death Receptor Up-Regulation.
Published in:
Science Translational Medicine, 2011, v. 3, n. 86, p. 1, doi. 10.1126/scitranslmed.3001384
By:
- Dolloff, Nathan G.;
- Mayes, Patrick A.;
- Hart, Lori S.;
- Dicker, David T.;
- Humphreys, Robin;
- El-Deiry, Wafik S.
Publication type:
Article
Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia.
Published in:
Cell Death & Disease, 2020, v. 11, n. 2, p. 1, doi. 10.1038/s41419-020-2303-9
By:
- Li, Yang;
- Gruber, Joshua J.;
- Litzenburger, Ulrike M.;
- Zhou, Yiren;
- Miao, Yu Rebecca;
- LaGory, Edward L.;
- Li, Albert M.;
- Hu, Zhen;
- Yip, Michaela;
- Hart, Lori S.;
- Maris, John M.;
- Chang, Howard Y.;
- Giaccia, Amato J.;
- Ye, Jiangbin
Publication type:
Article
Limited antitumor activity of combined BET and MEK inhibition in neuroblastoma.
Published in:
2020
By:
- Healy, Jason R.;
- Hart, Lori S.;
- Shazad, Alexander L.;
- Gagliardi, Maria E.;
- Tsang, Matthew;
- Elias, Jimmy;
- Ruden, Jacob;
- Farrel, Alvin;
- Rokita, Jo Lynne;
- Li, Yimei;
- Wyce, Anastasia;
- Barbash, Olena;
- Batra, Vandana;
- Samanta, Minu;
- Maris, John M.;
- Schnepp, Robert W.
Publication type:
journal article
CAMKV Is a Candidate Immunotherapeutic Target in MYCN Amplified Neuroblastoma.
Published in:
Frontiers in Oncology, 2020, p. 1, doi. 10.3389/fonc.2020.00302
By:
- Sussman, Robyn T.;
- Rokita, Jo Lynne;
- Huang, Kevin;
- Raman, Pichai;
- Rathi, Komal S.;
- Martinez, Daniel;
- Bosse, Kristopher R.;
- Lane, Maria;
- Hart, Lori S.;
- Bhatti, Tricia;
- Pawel, Bruce;
- Maris, John M.
Publication type:
Article

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