Found: 18
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The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).
- Published in:
- BMC Structural Biology, 2009, v. 9, p. 1, doi. 10.1186/1472-6807-9-7
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- Article
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease.
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- Human Molecular Genetics, 2014, v. 23, n. 11, p. 2858, doi. 10.1093/hmg/ddt674
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- Article
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02313-6
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- Article
The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility.
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- Nature Communications, 2014, v. 5, n. 11, p. 5470, doi. 10.1038/ncomms6470
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- Article
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 519, doi. 10.1038/nsmb.1793
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- Article
Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.
- Published in:
- Biochemical Journal, 2015, v. 468, n. 2, p. 283, doi. 10.1042/BJ20141492
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- Article
The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr–Abl activity in chronic myeloid leukemia
- Published in:
- Molecular Oncology, 2008, v. 2, n. 3, p. 272, doi. 10.1016/j.molonc.2008.07.003
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- Article
REGULATION OF THE C-ABL AND BCR-ABL TYROSINE KINASES.
- Published in:
- Nature Reviews Molecular Cell Biology, 2004, v. 5, n. 1, p. 33, doi. 10.1038/nrm1280
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- Article
Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23897-0
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- Article
Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains.
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- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17920-z
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- Article
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.
- Published in:
- EMBO Journal, 2008, v. 27, n. 15, p. 2135, doi. 10.1038/emboj.2008.126
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- Article
NMR Assignment Reveals an α-Helical Fold for the F-Actin Binding Domain of Human Bcr-Abl/c-Abl.
- Published in:
- Journal of Biomolecular NMR, 2005, v. 32, n. 4, p. 335, doi. 10.1007/s10858-005-8868-x
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- Article
Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions.
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- Nucleic Acids Research, 2017, v. 45, n. 18, p. 10504, doi. 10.1093/nar/gkx697
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- Article
The central domain of the matrix protein of HIV-1: influence on protein structure and virus infectivity.
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- Biological Chemistry, 2004, v. 385, n. 3/4, p. 303
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- Article
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16128-5
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- Article
An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells.
- Published in:
- Nature Methods, 2006, v. 3, n. 12, p. 1013, doi. 10.1038/nmeth968
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- Article
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K.
- Published in:
- Annals of Hematology, 2021, v. 100, n. 8, p. 2023, doi. 10.1007/s00277-020-04357-z
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- Article
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia.
- Published in:
- Nature Chemical Biology, 2012, v. 8, n. 3, p. 285, doi. 10.1038/nchembio.775
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- Article