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Benzoylurea Oligomers: Synthetic Foldamers That Mimic Extended α Helices.
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- Asian Journal of Control, 2013, v. 15, n. 6, p. 8614, doi. 10.1002/anie.200701869
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- Article
β-Strand Mimetic Foldamers Rigidified through Dipolar Repulsion.
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- Angewandte Chemie International Edition, 2015, v. 54, n. 9, p. 2649, doi. 10.1002/anie.201410290
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- Article
Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation.
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- Angewandte Chemie International Edition, 2014, v. 53, n. 14, p. 3650, doi. 10.1002/anie.201309353
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Cover Picture: Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation (Angew. Chem. Int. Ed. 14/2014).
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- Angewandte Chemie International Edition, 2014, v. 53, n. 14, p. 3521, doi. 10.1002/anie.201401099
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- Article
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23985-1
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- Article
Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and Activity.
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- ChemMedChem, 2020, v. 15, n. 20, p. 1932, doi. 10.1002/cmdc.202000474
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- Article
Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice.
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- Nature Biotechnology, 2000, v. 18, n. 10, p. 1065, doi. 10.1038/80257
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- Article
Synthesis of artificial receptors as potential candidates for recognition and binding of pterin analogs.
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- Journal of Heterocyclic Chemistry, 1995, v. 32, n. 2, p. 675, doi. 10.1002/jhet.5570320250
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- Article
β-Strand Mimetic Foldamers Rigidified through Dipolar Repulsion.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 9, p. 2687, doi. 10.1002/ange.201410290
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- Publication type:
- Article
Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation.
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- Angewandte Chemie, 2014, v. 126, n. 14, p. 3724, doi. 10.1002/ange.201309353
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- Publication type:
- Article
Titelbild: Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation (Angew. Chem. 14/2014).
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- Angewandte Chemie, 2014, v. 126, n. 14, p. 3591, doi. 10.1002/ange.201401099
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- Publication type:
- Article
pH-Dependent Conformational Switching in 2,6-Benzamidodiphenylacetylenes.
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- Angewandte Chemie, 2011, v. 123, n. 52, p. 12777, doi. 10.1002/ange.201106241
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- Article
Anion-Dependent Switching: Dynamically Controlling the Conformation of Hydrogen-Bonded Diphenylacetylenes.
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- Angewandte Chemie, 2011, v. 123, n. 20, p. 4693, doi. 10.1002/ange.201100144
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- Article
Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors.
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- Oncogene, 2005, v. 24, n. 29, p. 4701, doi. 10.1038/sj.onc.1208391
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- Article
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
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- Oncogene, 2003, v. 22, n. 40, p. 6257, doi. 10.1038/sj.onc.1206630
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- Article
A Calixarene with Four Peptide Loops: An Antibody Mimic for Recognition of Protein Surfaces.
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- Angewandte Chemie International Edition, 1997, v. 36, n. 23, p. 2680, doi. 10.1002/anie.199726801
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- Article
Rapid and Highly Selective Cleavage of Ribonucleoside 2′,3′-Cyclic Monophosphates by Dinuclear Cu<sup> II</sup> Complexes.
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- Angewandte Chemie International Edition, 1997, v. 36, n. 23, p. 2678, doi. 10.1002/anie.199726781
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- Article
Acceleration of a Phosphate Diester Transesterification Reaction by Bis(alkylguanidinium) Receptors Containing an Appended General Base.
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- Angewandte Chemie International Edition, 1995, v. 34, n. 11, p. 1237, doi. 10.1002/anie.199512371
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- Article
Novel Molecular Scaffolds: Formation of Helical Secondary Structure in a Family of Oligoanthranilamides.
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- Angewandte Chemie International Edition, 1994, v. 33, n. 4, p. 446, doi. 10.1002/anie.199404461
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- Article
A Self-Assembling, Hydrogen-Bonded Helix.
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- Angewandte Chemie International Edition, 1993, v. 32, n. 1, p. 119, doi. 10.1002/anie.199301191
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- Article
Synthesis Approaches to Analogues of the Vancomycin Family of Antibiotics.
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- Annals of the New York Academy of Sciences, 1986, v. 471, n. 1, p. 305, doi. 10.1111/j.1749-6632.1986.tb48049.x
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- Article
Improving Structural Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Aromatic Modifications.
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- ChemBioChem, 2022, v. 23, n. 6, p. 1, doi. 10.1002/cbic.202100670
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- Article
Protein surface recognition by synthetic agents: Design and structural requirements of a family of artificial receptors that bind to cytochrome C.
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- Biopolymers, 1998, v. 47, n. 4, p. 285, doi. 10.1002/(SICI)1097-0282(1998)47:4<285::AID-BIP4>3.0.CO;2-C
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- Article
Farnesyltransferase as a target for anticancer drug design.
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- Biopolymers, 1997, v. 43, n. 1, p. 25, doi. 10.1002/(SICI)1097-0282(1997)43:1<25::AID-BIP4>3.0.CO;2-2
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- Article
Label-free immunodetection with CMOS-compatible semiconducting nanowires.
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- Nature, 2007, v. 445, n. 7127, p. 519, doi. 10.1038/nature05498
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- Article
Design of growth factor antagonists with antiangiogenic and antitumor properties.
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- Oncogene, 2000, v. 19, n. 56, p. 6566, doi. 10.1038/sj.onc.1204121
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- Article
Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: Lessons from mechanism and bench-to-bedside translational studies.
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- Oncogene, 2000, v. 19, n. 56, p. 6584, doi. 10.1038/sj.onc.1204146
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- Article
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ.
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- Oncogene, 2000, v. 19, n. 48, p. 5525, doi. 10.1038/sj.onc.1203920
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- Article
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.
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- Oncogene, 1998, v. 16, n. 11, p. 1467, doi. 10.1038/sj.onc.1201656
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- Article
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.
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- Oncogene, 1997, v. 15, n. 11, p. 1283, doi. 10.1038/sj.onc.1201296
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- Article
Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
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- Carcinogenesis, 2000, v. 21, n. 1, p. 113, doi. 10.1093/carcin/21.1.113
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- Article
Cover Feature: α‐Helix‐Mimetic Foldamers for Targeting HIV‐1 TAR RNA (Chem. Eur. J. 30/2019).
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- Chemistry - A European Journal, 2019, v. 25, n. 30, p. 7230, doi. 10.1002/chem.201901752
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- Article
α‐Helix‐Mimetic Foldamers for Targeting HIV‐1 TAR RNA.
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- Chemistry - A European Journal, 2019, v. 25, n. 30, p. 7265, doi. 10.1002/chem.201900139
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- Article
Examination of the Effect of the Annealing Cation on Higher Order Structures Containing Guanine or Isoguanine Repeats.
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- Chemistry - A European Journal, 2009, v. 15, n. 42, p. 11244, doi. 10.1002/chem.200901047
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- Article
Inhibition of Chymotrypsin by a Self-Assembled DNA Quadruplex Functionalized with Cyclic Peptide Binding Fragments.
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- Chemistry - A European Journal, 2009, v. 15, n. 2, p. 328, doi. 10.1002/chem.200801637
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- Article
Synthesis and Self-Assembling Properties of Polymerizable Organogelators.
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- Chemistry - A European Journal, 2002, v. 8, n. 8, p. 1954, doi. 10.1002/1521-3765(20020415)8:8<1954::AID-CHEM1954>3.0.CO;2-X
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- Article
Synthetic α-Helix Mimetics as Agonists and Antagonists of Islet Amyloid Polypeptide Aggregation.
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- Angewandte Chemie, 2010, v. 122, n. 4, p. 748, doi. 10.1002/ange.200901694
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- Article
Self-Assembly of a Four-Helix Bundle on a DNA Quadruplex.
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- Angewandte Chemie, 2009, v. 121, n. 15, p. 2787, doi. 10.1002/ange.200804849
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- Article
Structurally Simple Farnesyltransferase Inhibitors Arrest the Growth of Malaria ParasitesThis work was supported by the Medicines for Malaria Venture (MMV) and NIH grants CA67771 and AI054384. S.-Y.C. thanks the Postdoctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF). O.H. gratefully acknowledges a postdoctoral fellowship of the German Academy of Natural Scientists Leopoldina (BMBF-LPD 9901/8-77). We thank David Floyd, Lou Lombardo and David Williams from Bristol-Myers Squibb for helpful suggestions.
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- Angewandte Chemie, 2005, v. 117, n. 31, p. 4981, doi. 10.1002/ange.200500674
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- Article
Strategien zur Modulation von Protein-Protein-Wechselwirkungen mit synthetischen Substanzen.
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- Angewandte Chemie, 2005, v. 117, n. 27, p. 4200, doi. 10.1002/ange.200461786
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- Article
Terphenyl-Based Helical Mimetics That Disrupt the p53/HDM2 InteractionWe thank the National Institutes of Health for support of this work (GM35208 and GM69850). The HDM2 pQE40 construct was kindly provided by Dr. Christian Klein (Hoffmann-La Roche, Inc.).
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- Angewandte Chemie, 2005, v. 117, n. 18, p. 2764, doi. 10.1002/ange.200462316
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- Article
A Tetraguanidinium Ligand Binds to the Surface of the Tetramerization Domain of Protein P53 ( X.S. and M.M. acknowledge the Generalitat de Catalunya for a predoctoral fellowship. This work was partially supported by grants from the Ministerio de Ciencia y Technlogía-FEDER (Grant no. BIO2002-2301) and the Generalitat de Catalunya (Grup Consolidat 1999SGR0042 and Centre de Referència en Biotecnologia). )
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- Angewandte Chemie, 2004, v. 116, n. 2, p. 198, doi. 10.1002/ange.200352115
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- Article
Design and Synthesis of Oligoamide-Based Double α-Helix Mimetics.
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- European Journal of Organic Chemistry, 2013, v. 2013, n. 17, p. 3433, doi. 10.1002/ejoc.201300363
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- Article
Design and Synthesis of Oligoamide-Based Double α-Helix Mimetics (Eur. J. Org. Chem. 17/2013).
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- European Journal of Organic Chemistry, 2013, v. 2013, n. 17, p. n/a, doi. 10.1002/ejoc.201390045
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- Article
Nitronate Anion Recognition and Modulation of Ambident Reactivity by Hydrogen-Bonding Receptors.
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- Chemistry - A European Journal, 2000, v. 6, n. 13, p. 2449, doi. 10.1002/1521-3765(20000703)6:13<2449::AID-CHEM2449>3.0.CO;2-9
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- Article
Helix Mimetics as Inhibitors of the Interaction of the Estrogen Receptor with Coactivator Peptides.
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- Angewandte Chemie International Edition, 2007, v. 46, n. 24, p. 4471, doi. 10.1002/anie.200700657
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- Article
Fiber Formation by Highly CO.
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- Angewandte Chemie International Edition, 2007, v. 46, n. 18, p. 3284, doi. 10.1002/anie.200604844
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- Article
Structurally Simple Farnesyltransferase Inhibitors Arrest the Growth of Malaria ParasitesThis work was supported by the Medicines for Malaria Venture (MMV) and NIH grants CA67771 and AI054384. S.-Y.C. thanks the Postdoctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF). O.H. gratefully acknowledges a postdoctoral fellowship of the German Academy of Natural Scientists Leopoldina (BMBF-LPD 9901/8-77). We thank David Floyd, Lou Lombardo and David Williams from Bristol-Myers Squibb for helpful suggestions.
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 31, p. 4903, doi. 10.1002/anie.200500674
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- Publication type:
- Article
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents.
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- Angewandte Chemie International Edition, 2005, v. 44, n. 27, p. 4130, doi. 10.1002/anie.200461786
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- Publication type:
- Article
Terphenyl-Based Helical Mimetics That Disrupt the p53/HDM2 InteractionWe thank the National Institutes of Health for support of this work (GM35208 and GM69850). The HDM2 pQE40 construct was kindly provided by Dr. Christian Klein (Hoffmann-La Roche, Inc.).
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 18, p. 2704, doi. 10.1002/anie.200462316
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- Publication type:
- Article