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Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Published in:
Nature Biotechnology, 2023, v. 41, n. 11, p. 1567, doi. 10.1038/s41587-023-01680-4
By:
- Hendriks, Delilah;
- Brouwers, Jos F.;
- Hamer, Karien;
- Geurts, Maarten H.;
- Luciana, Léa;
- Massalini, Simone;
- López-Iglesias, Carmen;
- Peters, Peter J.;
- Rodríguez-Colman, Maria J.;
- Chuva de Sousa Lopes, Susana;
- Artegiani, Benedetta;
- Clevers, Hans
Publication type:
Article
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
Published in:
EMBO Journal, 2013, v. 32, n. 20, p. 2708, doi. 10.1038/emboj.2013.204
By:
- Huch, Meritxell;
- Bonfanti, Paola;
- Boj, Sylvia F;
- Sato, Toshiro;
- Loomans, Cindy J M;
- van de Wetering, Marc;
- Sojoodi, Mozhdeh;
- Li, Vivian S W;
- Schuijers, Jurian;
- Gracanin, Ana;
- Ringnalda, Femke;
- Begthel, Harry;
- Hamer, Karien;
- Mulder, Joyce;
- van Es, Johan H;
- de Koning, Eelco;
- Vries, Robert G J;
- Heimberg, Harry;
- Clevers, Hans
Publication type:
Article
The Use of a Stringent Selection System Allows the Identification of DNA Elements that Augment Gene Expression.
Published in:
Molecular Biotechnology, 2011, v. 48, n. 1, p. 19, doi. 10.1007/s12033-010-9344-8
By:
- Hoeksema, Femke;
- Blokland, Rik;
- Siep, Michel;
- Hamer, Karien;
- Siersma, Tjalling;
- Blaauwen, Jan;
- Verhees, John;
- Otte, Arie
Publication type:
Article
In vitro expansion of single Lgr5<sup>+</sup> liver stem cells induced by Wnt-driven regeneration.
Published in:
Nature, 2013, v. 494, n. 7436, p. 247, doi. 10.1038/nature11826
By:
- Huch, Meritxell;
- Dorrell, Craig;
- Boj, Sylvia F.;
- van Es, Johan H.;
- Li, Vivian S. W.;
- van de Wetering, Marc;
- Sato, Toshiro;
- Hamer, Karien;
- Sasaki, Nobuo;
- Finegold, Milton J.;
- Haft, Annelise;
- Vries, Robert G.;
- Grompe, Markus;
- Clevers, Hans
Publication type:
Article

Found: 4

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.

The Use of a Stringent Selection System Allows the Identification of DNA Elements that Augment Gene Expression.

In vitro expansion of single Lgr5<sup>+</sup> liver stem cells induced by Wnt-driven regeneration.