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Evidence for the formation of functionally distinct αβγε GABAA receptors.
Published in:
Journal of Physiology, 2001, v. 537, n. 1, p. 101, doi. 10.1111/j.1469-7793.2001.0101k.x
By:
- Davies, Paul A.;
- Kirkness, Ewen F.;
- Hales, Tim G.
Publication type:
Article
Modulation by general anaesthetics of rat GABAA receptors comprised of α1 β3 and β3 subunits expressed in human embryonic kidney 293 cells.
Published in:
British Journal of Pharmacology, 1997, v. 120, n. 5, p. 899, doi. 10.1038/sj.bjp.0700987
By:
- Davies, Paul A;
- Kirkness, Ewen F;
- Hales, Tim G
Publication type:
Article
How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence.
Published in:
Cancers, 2019, v. 11, n. 5, p. 592, doi. 10.3390/cancers11050592
By:
- Forget, Patrice;
- Aguirre, Jose A.;
- Bencic, Ivanka;
- Borgeat, Alain;
- Cama, Allessandro;
- Condron, Claire;
- Eintrei, Christina;
- Eroles, Pilar;
- Gupta, Anil;
- Hales, Tim G.;
- Ionescu, Daniela;
- Johnson, Mark;
- Kabata, Pawel;
- Kirac, Iva;
- Ma, Daqing;
- Mokini, Zhirajr;
- Guerrero Orriach, Jose Luis;
- Retsky, Michael;
- Sandrucci, Sergio;
- Siekmann, Wiebke
Publication type:
Article
ß-Arrestin2 and c-Src Regulate the Constitutive Activity and Recycling of µ Opioid Receptors in Dorsal Root Ganglion Neurons.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 19, p. 5092, doi. 10.1523/JNEUROSCI.1157-07.2007
By:
- Walwyn, Wendy;
- Evans, Christopher J.;
- Hales, Tim G.
Publication type:
Article
Kinetics and Spontaneous Open Probability Conferred by the ε Subunit of the GABAA Receptor.
Published in:
Journal of Neuroscience, 2005, v. 25, n. 45, p. 10462, doi. 10.1523/JNEUROSCI.1658-05.2005
By:
- Wagner, David A.;
- Goldschen-Ohm, Marcel P.;
- Hales, Tim G.;
- Jones, Mathew V.
Publication type:
Article
A Structural Rationale for N‐Methylbicuculline Acting as a Promiscuous Competitive Antagonist of Inhibitory Pentameric Ligand‐Gated Ion Channels.
Published in:
ChemBioChem, 2020, v. 21, n. 10, p. 1526, doi. 10.1002/cbic.201900680
By:
- Jones, Mathew J.;
- Dawson, Alice;
- Hales, Tim G.;
- Hunter, William N.
Publication type:
Article
Morphine‐induced mechanical hypersensitivity in mice requires δ receptors, β‐arrestin2, and c‐Src activity.
Published in:
Journal of Physiology, 2023, v. 601, n. 8, p. 1483, doi. 10.1113/JP284003
By:
- Singleton, Samuel;
- Hales, Tim G.
Publication type:
Article
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2.
Published in:
Molecular Pain, 2011, v. 7, n. 1, p. 24, doi. 10.1186/1744-8069-7-24
By:
- Lam, Hoa;
- Maga, Matthew;
- Pradhan, Amynah;
- Evans, Christopher J;
- Maidment, Nigel T;
- Hales, Tim G.;
- Walwyn, Wendy
Publication type:
Article
TRV130 partial agonism and capacity to induce anti‐nociceptive tolerance revealed through reducing available μ‐opioid receptor number.
Published in:
British Journal of Pharmacology, 2021, v. 178, n. 8, p. 1855, doi. 10.1111/bph.15409
By:
- Singleton, Samuel;
- Baptista‐Hon, Daniel T.;
- Edelsten, Emily;
- McCaughey, Kirsty S.;
- Camplisson, Ewan;
- Hales, Tim G.
Publication type:
Article
Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.
Published in:
2020
By:
- Baptista‐Hon, Daniel T.;
- Smith, Mark;
- Singleton, Samuel;
- Antonides, Lysbeth H.;
- Nic Daeid, Niamh;
- McKenzie, Craig;
- Hales, Tim G.;
- Baptista-Hon, Daniel T
Publication type:
journal article
A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank.
Published in:
Human Molecular Genetics, 2020, v. 29, n. 8, p. 1396, doi. 10.1093/hmg/ddaa058
By:
- Meng, Weihua;
- Chan, Brian W;
- Harris, Cameron;
- Freidin, Maxim B;
- Hebert, Harry L;
- Adams, Mark J;
- Campbell, Archie;
- Hayward, Caroline;
- Zheng, Hua;
- Zhang, Xianwei;
- Colvin, Lesley A;
- Hales, Tim G;
- Palmer, Colin N A;
- Williams, Frances M K;
- McIntosh, Andrew;
- Smith, Blair H
Publication type:
Article
Loop G in the GABAA receptor α1 subunit influences gating efficacy.
Published in:
Journal of Physiology, 2017, v. 595, n. 5, p. 1725, doi. 10.1113/JP273752
By:
- Baptista‐Hon, Daniel T.;
- Gulbinaite, Simona;
- Hales, Tim G.
Publication type:
Article
A role for loop G in the β1 strand in GABAA receptor activation.
Published in:
Journal of Physiology, 2016, v. 594, n. 19, p. 5555, doi. 10.1113/JP272463
By:
- Baptista‐Hon, Daniel T.;
- Krah, Alexander;
- Zachariae, Ulrich;
- Hales, Tim G.
Publication type:
Article
Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABAA receptor spontaneous gating, agonist activation and desensitization.
Published in:
Journal of Physiology, 2012, v. 590, n. 1, p. 163, doi. 10.1113/jphysiol.2011.213249
By:
- Othman, Nidaa A.;
- Gallacher, Michael;
- Deeb, Tarek Z.;
- Baptista-Hon, Daniel T.;
- Perry, David C.;
- Hales, Tim G.
Publication type:
Article
A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function.
Published in:
Journal of Physiology, 2010, v. 588, n. 4, p. 603, doi. 10.1113/jphysiol.2009.181719
By:
- Wu, Dai-Fei;
- Othman, Nidaa A.;
- Sharp, Douglas;
- Mahendra, Arjun;
- Deeb, Tarek Z.;
- Hales, Tim G.
Publication type:
Article
Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors.
Published in:
Journal of Physiology, 2010, v. 588, n. 4, p. 587, doi. 10.1113/jphysiol.2009.183137
By:
- Peters, John A.;
- Cooper, Michelle A.;
- Carland, Jane E.;
- Livesey, Matthew R.;
- Hales, Tim G.;
- Lambert, Jeremy J.
Publication type:
Article
Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.
Published in:
Scientific Reports, 2015, p. 11541, doi. 10.1038/srep11541
By:
- House, Carrie D.;
- Wang, Bi-Dar;
- Ceniccola, Kristin;
- Williams, Russell;
- Simaan, May;
- Olender, Jacqueline;
- Patel, Vyomesh;
- Baptista-Hon, Daniel T.;
- Annunziata, Christina M.;
- Silvio Gutkind, J.;
- Hales, Tim G.;
- Lee, Norman H.
Publication type:
Article
Editorial: Opioids in the time of the COVID-19 pandemic: from cellular mechanisms to public health policy.
Published in:
Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1251958
By:
- John, Scott;
- Walwyn, David R.;
- DeFea, Kathryn;
- Hales, Tim G.;
- Walwyn, Wendy
Publication type:
Article
Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors.
Published in:
2015
By:
- Morton, Russell A;
- Baptista-Hon, Daniel T;
- Hales, Tim G;
- Lovinger, David M
Publication type:
journal article
Agonist- and antagonist-induced up-regulation of surface 5- HT3 A receptors.
Published in:
British Journal of Pharmacology, 2015, v. 172, n. 16, p. 4066, doi. 10.1111/bph.13197
By:
- Morton, Russell A;
- Baptista ‐ Hon, Daniel T;
- Hales, Tim G;
- Lovinger, David M
Publication type:
Article
The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine.
Published in:
2012
By:
- Baptista-Hon DT;
- Deeb TZ;
- Othman NA;
- Sharp D;
- Hales TG;
- Baptista-Hon, Daniel T;
- Deeb, Tarek Z;
- Othman, Nidaa A;
- Sharp, Douglas;
- Hales, Tim G
Publication type:
journal article
The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine.
Published in:
British Journal of Pharmacology, 2012, v. 165, n. 3, p. 693, doi. 10.1111/j.1476-5381.2011.01582.x
By:
- Baptista-Hon, Daniel T;
- Deeb, Tarek Z;
- Othman, Nidaa A;
- Sharp, Douglas;
- Hales, Tim G
Publication type:
Article
GABA Has Excitatory Actions on GnRH-Secreting Immortalized Hypothalamic (GT1-7) Neurons.
Published in:
Neuroendocrinology, 1994, v. 59, n. 3, p. 297, doi. 10.1159/000126671
By:
- Hales, Tim G.;
- Sanderson, Michael J.;
- Charles, Andrew C.
Publication type:
Article
Evidence for Expression of Heteromeric Serotonin 5-HT3 Receptors in Rodents.
Published in:
Journal of Neurochemistry, 2000, v. 75, n. 1, p. 240, doi. 10.1046/j.1471-4159.2000.0750240.x
By:
- Hanna, Michael C.;
- Davies, Paul A.;
- Hales, Tim G.;
- Kirkness, Ewen F.
Publication type:
Article
The 5-HT3B subunit is a major determinant of serotonin-receptor function.
Published in:
Nature, 1999, v. 397, n. 6717, p. 359, doi. 10.1038/16941
By:
- Davies, Paul A.;
- Pistis, Marco;
- Hanna, Michael C.;
- Peters, John A.;
- Lambert, Jeremy J.;
- Hales, Tim G.;
- Kirkness, Ewen F.
Publication type:
Article
The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis.
Published in:
BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03505-w
By:
- Senaratne, Dhaneesha N. S.;
- Thakkar, Bhushan;
- Smith, Blair H.;
- Hales, Tim G.;
- Marryat, Louise;
- Colvin, Lesley A.
Publication type:
Article

Found: 26

Evidence for the formation of functionally distinct αβγε GABA<sub>A</sub> receptors.

Modulation by general anaesthetics of rat GABA<sub>A</sub> receptors comprised of α1 β3 and β3 subunits expressed in human embryonic kidney 293 cells.

How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence.

ß-Arrestin2 and c-Src Regulate the Constitutive Activity and Recycling of µ Opioid Receptors in Dorsal Root Ganglion Neurons.

Kinetics and Spontaneous Open Probability Conferred by the ε Subunit of the GABA<sub>A</sub> Receptor.

A Structural Rationale for N‐Methylbicuculline Acting as a Promiscuous Competitive Antagonist of Inhibitory Pentameric Ligand‐Gated Ion Channels.

Morphine‐induced mechanical hypersensitivity in mice requires δ receptors, β‐arrestin2, and c‐Src activity.

Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2.

TRV130 partial agonism and capacity to induce anti‐nociceptive tolerance revealed through reducing available μ‐opioid receptor number.

Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank.

Loop G in the GABA<sub>A</sub> receptor α1 subunit influences gating efficacy.

A role for loop G in the β1 strand in GABA<sub>A</sub> receptor activation.

Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA<sub>A</sub> receptor spontaneous gating, agonist activation and desensitization.

A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT<sub>3</sub> receptor function.

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors.

Voltage-gated Na<sup>+</sup> Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.

Editorial: Opioids in the time of the COVID-19 pandemic: from cellular mechanisms to public health policy.

Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors.

Agonist- and antagonist-induced up-regulation of surface 5- HT<sub>3</sub> A receptors.

The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine.

The 5-HT3B subunit affects high-potency inhibition of 5-HT<sub>3</sub> receptors by morphine.

GABA Has Excitatory Actions on GnRH-Secreting Immortalized Hypothalamic (GT1-7) Neurons.

Evidence for Expression of Heteromeric Serotonin 5-HT<sub>3</sub> Receptors in Rodents.

The 5-HT3B subunit is a major determinant of serotonin-receptor function.

The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis.