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Therapeutic Performance Evaluation of 213 Bi-Labelled Aminopeptidase N (APN/CD13)-Affine NGR-Motif ([ 213 Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology.
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- Pharmaceutics, 2023, v. 15, n. 2, p. 491, doi. 10.3390/pharmaceutics15020491
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- Article
Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1111, doi. 10.3390/ph14111111
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Combination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5-HT<sub>6</sub> Antagonists from Large Commercial Repositories.
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- Chemical Biology & Drug Design, 2015, v. 86, n. 4, p. 864, doi. 10.1111/cbdd.12563
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- Article
Overview of Prostaglandin E2 (PGE2)-Targeting Radiolabelled Imaging Probes from Preclinical Perspective: Lessons Learned and Road Ahead.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 6942, doi. 10.3390/ijms24086942
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- Article
In Vivo Preclinical Assessment of β-Amyloid–Affine [ 11 C]C-PIB Accumulation in Aluminium-Induced Alzheimer's Disease-Resembling Hypercholesterinaemic Rat Model.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13950, doi. 10.3390/ijms232213950
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- Article
Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer's Disease: From In Silico to In Vivo.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13098, doi. 10.3390/ijms232113098
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- Article
In Vivo Assessments of Mesoblastic Nephroma (Ne/De) and Myelomonoblastic Leukaemia (My1/De) Tumour Development in Hypercholesterolemia Rat Models.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13060, doi. 10.3390/ijms232113060
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- Article
PET Probes for Preclinical Imaging of GRPR-Positive Prostate Cancer: Comparative Preclinical Study of [ 68 Ga]Ga-NODAGA-AMBA and [ 44 Sc]Sc-NODAGA-AMBA.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 10061, doi. 10.3390/ijms231710061
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- Article
Acute Myelomonoblastic Leukemia (My1/De): A Preclinical Rat Model.
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- In Vivo, 2024, v. 38, n. 3, p. 1064, doi. 10.21873/invivo.13540
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- Article
Concomitant [<sup>18</sup>F]F-FAZA and [<sup>18</sup>F]F-FDG Imaging of Gynecological Cancer Xenografts: Insight into Tumor Hypoxia.
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- In Vivo, 2024, v. 38, n. 2, p. 574, doi. 10.21873/invivo.13476
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- Article
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-20182-y
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- Article
Robust Recombinant Expression of Human Placental Ribonuclease Inhibitor in Insect Cells.
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- Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 273, doi. 10.3390/biom12020273
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- Article
Ligand-induced conformational rearrangements regulate the switch between membrane-proximal and distal functions of Rho kinase 2.
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- Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01450-x
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- Article
Matrix Metalloproteinase Inhibitors: A Critical Appraisal of Design Principles and Proposed Therapeutic Utility.
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- Drugs, 2010, v. 70, n. 8, p. 949
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- Article
A versatile modular vector set for optimizing protein expression among bacterial, yeast, insect and mammalian hosts.
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- PLoS ONE, 2019, v. 14, n. 12, p. N.PAG, doi. 10.1371/journal.pone.0227110
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Advances in Producing Functional Circuits on Biodegradable PCBs.
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- Periodica Polytechnica: Electrical Engineering & Computer Science, 2016, v. 60, n. 4, p. 223, doi. 10.3311/PPee.9690
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- Article
Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00296
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- Article
Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening.
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- Molecular Diversity, 2017, v. 21, n. 1, p. 175, doi. 10.1007/s11030-016-9717-4
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Combining 2D and 3D in silico methods for rapid selection of potential PDE5 inhibitors from multimillion compounds' repositories: biological evaluation.
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- Molecular Diversity, 2012, v. 16, n. 1, p. 59, doi. 10.1007/s11030-011-9335-0
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- Article
Structural plasticity of the Salmonella FliS flagellar export chaperone.
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- FEBS Letters, 2016, v. 590, n. 8, p. 1103, doi. 10.1002/1873-3468.12149
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- Article
Rapid Identification of Potential Drug Candidates from Multi-Million Compounds' Repositories. Combination of 2D Similarity Search with 3D Ligand/Structure Based Methods and In Vitro Screening.
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- Molecules, 2021, v. 26, n. 18, p. 5593, doi. 10.3390/molecules26185593
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- Article
Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches.
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- Molecules, 2019, v. 24, n. 20, p. 3641, doi. 10.3390/molecules24203641
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- Article
Combination of 2D/3D Ligand-Based Similarity Search in Rapid Virtual Screening from Multimillion Compound Repositories. Selection and Biological Evaluation of Potential PDE4 and PDE5 Inhibitors.
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- Molecules, 2014, v. 19, n. 6, p. 7008, doi. 10.3390/molecules19067008
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- Article
In Vivo Imaging of Hypoxia and Neoangiogenesis in Experimental Syngeneic Hepatocellular Carcinoma Tumor Model Using Positron Emission Tomography.
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- BioMed Research International, 2020, p. 1, doi. 10.1155/2020/4952372
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Adjustment of conformational flexibility of glyceraldehyde-3-phosphate dehydrogenase as a means of thermal adaptation and allosteric regulation.
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- European Biophysics Journal, 2008, v. 37, n. 7, p. 1139, doi. 10.1007/s00249-008-0332-x
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Design, Selection, and Evaluation of a General Kinase-Focused Library.
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- ChemMedChem, 2009, v. 4, n. 8, p. 1273, doi. 10.1002/cmdc.200900164
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- Article
SARS-CoV-2 Nucleocapsid Protein Is Not Responsible for Over-Activation of Complement Lectin Pathway.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 13, p. 7343, doi. 10.3390/ijms25137343
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- Article
Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10416, doi. 10.3390/ijms241310416
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Evolution of the concept of conformational dynamics of enzyme functions over half of a century: A personal view.
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- Biopolymers, 2013, v. 99, n. 4, p. 263, doi. 10.1002/bip.22159
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- Article