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FISH diagnostics in hematological malignancies.
- Published in:
- 2005
- By:
- Publication type:
- Journal Article
Gene expression profiling in acute leukemia: diagnostics of the future?
- Published in:
- 2004
- By:
- Publication type:
- Journal Article
Genexpressionsanalysen bei akuten Leukämien: Diagnostik der Zukunft?
- Published in:
- Journal of Laboratory Medicine / Laboratoriums Medizin, 2004, v. 28, n. 3, p. 225
- By:
- Publication type:
- Article
The new WHO classification for acute myeloid leukemias: comparison to the FAB classification.
- Published in:
- 2002
- By:
- Publication type:
- Journal Article
Die neue WHO-Klassifikation zur Einteilung der akuten myeloischen Leukämien (AML): Vorteile und Probleme im Vergleich zur FAB (French-American-British)-Klassifikation.
- Published in:
- Journal of Laboratory Medicine / Laboratoriums Medizin, 2002, v. 26, n. 1/2, p. 19
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- Publication type:
- Article
Molecular Genetics of MDS.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2018, v. 18, p. S45, doi. 10.1016/j.clml.2018.06.052
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- Publication type:
- Article
Diagnostik akuter Leukämien.
- Published in:
- Der Pathologe, 2012, v. 33, n. 6, p. 528, doi. 10.1007/s00292-012-1653-1
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- Publication type:
- Article
KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 6, p. 1223, doi. 10.1038/leu.2015.24
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- Publication type:
- Article
Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 5, p. 1115, doi. 10.1038/leu.2015.4
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- Publication type:
- Article
WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 3, p. 660, doi. 10.1038/leu.2014.243
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- Publication type:
- Article
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status.
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- Leukemia (08876924), 2014, v. 28, n. 12, p. 2292, doi. 10.1038/leu.2014.272
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- Publication type:
- Article
High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome.
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- Leukemia (08876924), 2014, v. 28, n. 7, p. 1449, doi. 10.1038/leu.2014.4
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- Publication type:
- Article
Low rate of calreticulin mutations in refractory anaemia with ring sideroblasts and marked thrombocytosis.
- Published in:
- Leukemia (08876924), 2014, v. 28, n. 6, p. 1374, doi. 10.1038/leu.2014.49
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- Publication type:
- Article
The role of different genetic subtypes of CEBPA mutated AML.
- Published in:
- Leukemia (08876924), 2014, v. 28, n. 4, p. 794, doi. 10.1038/leu.2013.273
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- Publication type:
- Article
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes.
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- Leukemia (08876924), 2014, v. 28, n. 2, p. 241, doi. 10.1038/leu.2013.336
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- Publication type:
- Article
Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease.
- Published in:
- Leukemia (08876924), 2014, v. 28, n. 1, p. 129, doi. 10.1038/leu.2013.239
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- Publication type:
- Article
SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients.
- Published in:
- Leukemia (08876924), 2014, v. 28, n. 1, p. 108, doi. 10.1038/leu.2013.263
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- Publication type:
- Article
Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 12, p. 2393, doi. 10.1038/leu.2013.218
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- Publication type:
- Article
SOX11 overexpression is a specific marker for mantle cell lymphoma and correlates with t(11;14) translocation, CCND1 expression and an adverse prognosis.
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- Leukemia (08876924), 2013, v. 27, n. 12, p. 2388, doi. 10.1038/leu.2013.141
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- Publication type:
- Article
Age, JAK2(V617F) and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis.
- Published in:
- 2013
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- Publication type:
- journal article
High incidence of RAS signalling pathway mutations in MLL-rearranged acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 9, p. 1933, doi. 10.1038/leu.2013.90
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- Publication type:
- Article
Acute erythroid leukemia (AEL) can be separated into distinct prognostic subsets based on cytogenetic and molecular genetic characteristics.
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- Leukemia (08876924), 2013, v. 27, n. 9, p. 1940, doi. 10.1038/leu.2013.144
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- Publication type:
- Article
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 9, p. 1852, doi. 10.1038/leu.2013.133
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- Publication type:
- Article
Age, JAK2<sup>V617F</sup> and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 9, p. 1826, doi. 10.1038/leu.2013.120
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- Publication type:
- Article
Landmark analysis of DNMT3A mutations in hematological malignancies.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 7, p. 1573, doi. 10.1038/leu.2013.65
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- Publication type:
- Article
STAT3 mutations are highly specific for large granular lymphocytic leukemia.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 7, p. 1598, doi. 10.1038/leu.2012.350
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- Publication type:
- Article
Molecular mutations are prognostically relevant in AML with intermediate risk cytogenetics and aberrant karyotype.
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- Leukemia (08876924), 2013, v. 27, n. 2, p. 496, doi. 10.1038/leu.2012.200
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- Publication type:
- Article
GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis.
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- Leukemia (08876924), 2013, v. 27, n. 2, p. 482, doi. 10.1038/leu.2012.174
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- Publication type:
- Article
A rare but specific subset of adult AML patients can be defined by the cytogenetically cryptic NUP98-NSD1 fusion gene.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 1, p. 245, doi. 10.1038/leu.2012.230
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- Publication type:
- Article
ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome.
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- Leukemia (08876924), 2013, v. 27, n. 1, p. 82, doi. 10.1038/leu.2012.262
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- Publication type:
- Article
Landscape of TET2 mutations in acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2012, v. 26, n. 5, p. 934, doi. 10.1038/leu.2011.326
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- Publication type:
- Article
Deletion of the tumor-suppressor gene NF1 occurs in 5% of myeloid malignancies and is accompanied by a mutation in the remaining allele in half of the cases.
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- Leukemia (08876924), 2012, v. 26, n. 4, p. 834, doi. 10.1038/leu.2011.296
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- Publication type:
- Article
Prognosis in patients with MDS or AML and bone marrow blasts between 10% and 30% is not associated with blast counts but depends on cytogenetic and molecular genetic characteristics.
- Published in:
- 2011
- By:
- Publication type:
- Letter
Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 8, p. 1297, doi. 10.1038/leu.2011.97
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- Publication type:
- Article
The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.
- Published in:
- 2011
- By:
- Publication type:
- letter
Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.
- Published in:
- 2011
- By:
- Publication type:
- letter
Characterization of NPM1-mutated AML with a history of myelodysplastic syndromes or myeloproliferative neoplasms.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 4, p. 615, doi. 10.1038/leu.2010.299
- By:
- Publication type:
- Article
An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling.
- Published in:
- 2011
- By:
- Publication type:
- Letter
Targeted next-generation sequencing detects point mutations, insertions, deletions and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 4, p. 671, doi. 10.1038/leu.2010.309
- By:
- Publication type:
- Article
A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases.
- Published in:
- 2011
- By:
- Publication type:
- Letter
Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML.
- Published in:
- 2010
- By:
- Publication type:
- letter
BAALC-associated gene expression profiles define IGFBP7 as a novel molecular marker in acute leukemia.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 8, p. 1429, doi. 10.1038/leu.2010.130
- By:
- Publication type:
- Article
Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways.
- Published in:
- 2010
- By:
- Publication type:
- Letter
AML with CBFB–MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 5, p. 1065, doi. 10.1038/leu.2010.22
- By:
- Publication type:
- Article
The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1.
- Published in:
- 2010
- By:
- Publication type:
- letter
Similar patterns of chromosome abnormalities in CML occur in addition to the Philadelphia chromosome with or without tyrosine kinase inhibitor treatment.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 3, p. 638, doi. 10.1038/leu.2009.222
- By:
- Publication type:
- Article
High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG.
- Published in:
- Leukemia (08876924), 2009, v. 23, n. 12, p. 2248, doi. 10.1038/leu.2009.183
- By:
- Publication type:
- Article
Identification of additional cytogenetic and molecular genetic abnormalities in acute myeloid leukaemia with t(8;21)/ AML1-ETO.
- Published in:
- British Journal of Haematology, 2006, v. 134, n. 6, p. 616, doi. 10.1111/j.1365-2141.2006.06229.x
- By:
- Publication type:
- Article
The pharmacodynamic basis for the increased antileukaemic efficacy of cytosine arabinoside-based treatment regimens in acute myeloid leukaemia with a high proliferative activity.
- Published in:
- British Journal of Haematology, 2000, v. 110, n. 1, p. 170, doi. 10.1046/j.1365-2141.2000.02151.x
- By:
- Publication type:
- Article
New insights into the biology of multiple myeloma using a combination of May-Grünwald-Giemsa staining and fluorescence in situ hybridization techniques at the single cell level.
- Published in:
- 2001
- By:
- Publication type:
- journal article