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Early allo-SCT for AML with a complex aberrant karyotype-results from a prospective pilot study.
- Published in:
- Bone Marrow Transplantation, 2012, v. 47, n. 1, p. 46, doi. 10.1038/bmt.2011.15
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- Publication type:
- Article
Occurrence of AML in cells of donor origin after treatment of CML in relapse with imatinib and donor stem cell boost 16 years after the original allogeneic BMT.
- Published in:
- 2009
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- Publication type:
- Case Study
Interactive diagnostics in the indication to allogeneic SCT in AML.
- Published in:
- Bone Marrow Transplantation, 2009, v. 43, n. 10, p. 745, doi. 10.1038/bmt.2009.54
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- Publication type:
- Article
Successful allogeneic stem cell transplantation in second chronic-phase CML induced by the tyrosine kinase inhibitor nilotinib (AMN107) after blast crisis under imatinib.
- Published in:
- 2007
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- Publication type:
- Letter
Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 9, p. 1942, doi. 10.1038/leu.2015.49
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- Publication type:
- Article
WT1 mutations are secondary events in AML, show varying frequencies and impact on prognosis between genetic subgroups.
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- Leukemia (08876924), 2015, v. 29, n. 3, p. 660, doi. 10.1038/leu.2014.243
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- Publication type:
- Article
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status.
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- Leukemia (08876924), 2014, v. 28, n. 12, p. 2292, doi. 10.1038/leu.2014.272
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- Publication type:
- Article
High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome.
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- Leukemia (08876924), 2014, v. 28, n. 7, p. 1449, doi. 10.1038/leu.2014.4
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- Publication type:
- Article
The role of different genetic subtypes of CEBPA mutated AML.
- Published in:
- Leukemia (08876924), 2014, v. 28, n. 4, p. 794, doi. 10.1038/leu.2013.273
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- Publication type:
- Article
Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease.
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- Leukemia (08876924), 2014, v. 28, n. 1, p. 129, doi. 10.1038/leu.2013.239
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- Publication type:
- Article
SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients.
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- Leukemia (08876924), 2014, v. 28, n. 1, p. 108, doi. 10.1038/leu.2013.263
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- Publication type:
- Article
Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 12, p. 2393, doi. 10.1038/leu.2013.218
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- Publication type:
- Article
SOX11 overexpression is a specific marker for mantle cell lymphoma and correlates with t(11;14) translocation, CCND1 expression and an adverse prognosis.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 12, p. 2388, doi. 10.1038/leu.2013.141
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- Publication type:
- Article
Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 11, p. 2254, doi. 10.1038/leu.2013.129
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- Publication type:
- Article
High incidence of RAS signalling pathway mutations in MLL-rearranged acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 9, p. 1933, doi. 10.1038/leu.2013.90
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- Publication type:
- Article
Acute erythroid leukemia (AEL) can be separated into distinct prognostic subsets based on cytogenetic and molecular genetic characteristics.
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- Leukemia (08876924), 2013, v. 27, n. 9, p. 1940, doi. 10.1038/leu.2013.144
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- Publication type:
- Article
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 9, p. 1852, doi. 10.1038/leu.2013.133
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- Publication type:
- Article
Landmark analysis of DNMT3A mutations in hematological malignancies.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 7, p. 1573, doi. 10.1038/leu.2013.65
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- Publication type:
- Article
STAT3 mutations are highly specific for large granular lymphocytic leukemia.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 7, p. 1598, doi. 10.1038/leu.2012.350
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- Publication type:
- Article
A novel recurrent AML1-ETO fusion: tight in vivo association with BCR-ABL1.
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- Leukemia (08876924), 2013, v. 27, n. 6, p. 1397, doi. 10.1038/leu.2013.53
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- Publication type:
- Article
GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 2, p. 482, doi. 10.1038/leu.2012.174
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- Publication type:
- Article
Molecular mutations are prognostically relevant in AML with intermediate risk cytogenetics and aberrant karyotype.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 2, p. 496, doi. 10.1038/leu.2012.200
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- Publication type:
- Article
A rare but specific subset of adult AML patients can be defined by the cytogenetically cryptic NUP98-NSD1 fusion gene.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 1, p. 245, doi. 10.1038/leu.2012.230
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- Publication type:
- Article
ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 1, p. 82, doi. 10.1038/leu.2012.262
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- Publication type:
- Article
Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML)
- Published in:
- 2012
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- Publication type:
- Journal Article
Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML).
- Published in:
- Leukemia (08876924), 2012, v. 26, n. 9, p. 2096, doi. 10.1038/leu.2012.85
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- Publication type:
- Article
Landscape of TET2 mutations in acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2012, v. 26, n. 5, p. 934, doi. 10.1038/leu.2011.326
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- Publication type:
- Article
Deletion of the tumor-suppressor gene NF1 occurs in 5% of myeloid malignancies and is accompanied by a mutation in the remaining allele in half of the cases.
- Published in:
- Leukemia (08876924), 2012, v. 26, n. 4, p. 834, doi. 10.1038/leu.2011.296
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- Publication type:
- Article
Eμ/miR-125b transgenic mice develop lethal B-cell malignancies.
- Published in:
- 2011
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- Publication type:
- journal article
Prognosis in patients with MDS or AML and bone marrow blasts between 10% and 30% is not associated with blast counts but depends on cytogenetic and molecular genetic characteristics.
- Published in:
- 2011
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- Publication type:
- Letter
Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 8, p. 1297, doi. 10.1038/leu.2011.97
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- Publication type:
- Article
The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.
- Published in:
- 2011
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- Publication type:
- Letter
Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance.
- Published in:
- 2011
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- Publication type:
- Letter
Targeted next-generation sequencing detects point mutations, insertions, deletions and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 4, p. 671, doi. 10.1038/leu.2010.309
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- Publication type:
- Article
Characterization of NPM1-mutated AML with a history of myelodysplastic syndromes or myeloproliferative neoplasms.
- Published in:
- Leukemia (08876924), 2011, v. 25, n. 4, p. 615, doi. 10.1038/leu.2010.299
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- Publication type:
- Article
An accumulation of cytogenetic and molecular genetic events characterizes the progression from MDS to secondary AML: an analysis of 38 paired samples analyzed by cytogenetics, molecular mutation analysis and SNP microarray profiling.
- Published in:
- 2011
- By:
- Publication type:
- Letter
A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases.
- Published in:
- 2011
- By:
- Publication type:
- Letter
Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML.
- Published in:
- 2010
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- Publication type:
- Letter
AML with CBFB–MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 5, p. 1065, doi. 10.1038/leu.2010.22
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- Publication type:
- Article
Similar patterns of chromosome abnormalities in CML occur in addition to the Philadelphia chromosome with or without tyrosine kinase inhibitor treatment.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 3, p. 638, doi. 10.1038/leu.2009.222
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- Publication type:
- Article
High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG.
- Published in:
- Leukemia (08876924), 2009, v. 23, n. 12, p. 2248, doi. 10.1038/leu.2009.183
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- Publication type:
- Article
Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity.
- Published in:
- 2009
- By:
- Publication type:
- Letter
AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features.
- Published in:
- 2009
- By:
- Publication type:
- journal article
The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype.
- Published in:
- Leukemia (08876924), 2009, v. 23, n. 1, p. 117, doi. 10.1038/leu.2008.274
- By:
- Publication type:
- Article
Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype.
- Published in:
- 2008
- By:
- Publication type:
- journal article
A new case with rare e6a2 BCR–ABL fusion transcript developing two new resistance mutations during imatinib mesylate, which were replaced by T315I after subsequent dasatinib treatment.
- Published in:
- 2008
- By:
- Publication type:
- Letter
Detection of an MPLW515 mutation in a case with features of both essential thrombocythemia and refractory anemia with ringed sideroblasts and thrombocytosis.
- Published in:
- 2008
- By:
- Publication type:
- Letter
Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV<sub>H</sub> status and immunophenotyping.
- Published in:
- Leukemia (08876924), 2007, v. 21, n. 12, p. 2442, doi. 10.1038/sj.leu.2404935
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- Publication type:
- Article
JAK2V617F as progression marker in CMPD and as cooperative mutation in AML with trisomy 8 and t(8;21): a comparative study on 1103 CMPD and 269 AML cases.
- Published in:
- 2007
- By:
- Publication type:
- Letter
The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors.
- Published in:
- Leukemia (08876924), 2007, v. 21, n. 6, p. 1177, doi. 10.1038/sj.leu.2404659
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- Publication type:
- Article