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3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38044-0
By:
- Okonechnikov, Konstantin;
- Camgöz, Aylin;
- Chapman, Owen;
- Wani, Sameena;
- Park, Donglim Esther;
- Hübner, Jens-Martin;
- Chakraborty, Abhijit;
- Pagadala, Meghana;
- Bump, Rosalind;
- Chandran, Sahaana;
- Kraft, Katerina;
- Acuna-Hidalgo, Rocio;
- Reid, Derek;
- Sikkink, Kristin;
- Mauermann, Monika;
- Juarez, Edwin F.;
- Jenseit, Anne;
- Robinson, James T.;
- Pajtler, Kristian W.;
- Milde, Till
Publication type:
Article
EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.
Published in:
Neuro-Oncology, 2019, v. 21, n. 7, p. 878, doi. 10.1093/neuonc/noz058
By:
- Hübner, Jens-Martin;
- Müller, Torsten;
- Papageorgiou, Dimitris N;
- Mauermann, Monika;
- Krijgsveld, Jeroen;
- Russell, Robert B;
- Ellison, David W;
- Pfister, Stefan M;
- Pajtler, Kristian W;
- Kool, Marcel
Publication type:
Article
GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii80, doi. 10.1093/neuonc/noz036.073
By:
- Okonechnikov, Konstantin;
- Hübner, Jens-Martin;
- Kraft, Katerina;
- Hidalgo, Rocio Acuna;
- Bump, Rosalind;
- Chandran, Sahaana;
- Mundlos, Stefan;
- Mesirov, Jill;
- Pajtler, Kristian;
- Dixon, Jesse;
- Pfister, Stefan;
- Kool, Marcel;
- Chavez, Lukas
Publication type:
Article
EPEN-04. CXorf67 MIMICS ONCOGENIC HISTONE H3 K27M MUTATIONS AND FUNCTIONS AS INTRINSIC INHIBITOR OF PRC2 FUNCTION IN AGGRESSIVE POSTERIOR FOSSA EPENDYMOMA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii78, doi. 10.1093/neuonc/noz036.062
By:
- Hübner, Jens-Martin;
- Müller, Torsten;
- Papageorgiou, Dimitris N;
- Krijgsveld, Jeroen;
- Russell, Robert B;
- Ellison, David W;
- Pfister, Stefan M;
- Pajtler, Kristian W;
- Kool, Marcel
Publication type:
Article
Targeting fibroblast growth factor receptors to combat aggressive ependymoma.
Published in:
Acta Neuropathologica, 2021, v. 142, n. 2, p. 339, doi. 10.1007/s00401-021-02327-x
By:
- Lötsch, Daniela;
- Kirchhofer, Dominik;
- Englinger, Bernhard;
- Jiang, Li;
- Okonechnikov, Konstantin;
- Senfter, Daniel;
- Laemmerer, Anna;
- Gabler, Lisa;
- Pirker, Christine;
- Donson, Andrew M.;
- Bannauer, Peter;
- Korbel, Pia;
- Jaunecker, Carola N.;
- Hübner, Jens-Martin;
- Mayr, Lisa;
- Madlener, Sibylle;
- Schmook, Maria T.;
- Ricken, Gerda;
- Maaß, Kendra;
- Grusch, Michael
Publication type:
Article
Heterogeneity within the PF-EPN-B ependymoma subgroup.
Published in:
Acta Neuropathologica, 2018, v. 136, n. 2, p. 227, doi. 10.1007/s00401-018-1888-x
By:
- Cavalli, Florence M. G.;
- Hübner, Jens-Martin;
- Sharma, Tanvi;
- Luu, Betty;
- Sill, Martin;
- Zapotocky, Michal;
- Mack, Stephen C.;
- Witt, Hendrik;
- Lin, Tong;
- Shih, David J. H.;
- Ho, Ben;
- Santi, Mariarita;
- Emery, Lyndsey;
- Hukin, Juliette;
- Dunham, Christopher;
- McLendon, Roger E.;
- Lipp, Eric S.;
- Gururangan, Sridharan;
- Grossbach, Andrew;
- French, Pim
Publication type:
Article
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.
Published in:
Acta Neuropathologica, 2018, v. 136, n. 2, p. 211, doi. 10.1007/s00401-018-1877-0
By:
- Pajtler, Kristian W.;
- Wen, Ji;
- Sill, Martin;
- Lin, Tong;
- Orisme, Wilda;
- Tang, Bo;
- Hübner, Jens-Martin;
- Ramaswamy, Vijay;
- Jia, Sujuan;
- Dalton, James D.;
- Haupfear, Kelly;
- Rogers, Hazel A.;
- Punchihewa, Chandanamali;
- Lee, Ryan;
- Easton, John;
- Wu, Gang;
- Ritzmann, Timothy A.;
- Chapman, Rebecca;
- Chavez, Lukas;
- Boop, Fredrick A.
Publication type:
Article

Found: 7

3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.

EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.

GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS.

EPEN-04. CXorf67 MIMICS ONCOGENIC HISTONE H3 K27M MUTATIONS AND FUNCTIONS AS INTRINSIC INHIBITOR OF PRC2 FUNCTION IN AGGRESSIVE POSTERIOR FOSSA EPENDYMOMA.

Targeting fibroblast growth factor receptors to combat aggressive ependymoma.

Heterogeneity within the PF-EPN-B ependymoma subgroup.

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.