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Isolierung, Strukturaufklärung und (Bio-)Synthese von Haprolid, einem zellspezifisch zytotoxischen myxobakteriellen Makrolidnaturstoff.
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- Angewandte Chemie, 2016, v. 128, n. 34, p. 10267, doi. 10.1002/ange.201603288
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- Article
Isolation and Structure Elucidation of Cruentarens A and B — Novel Members of the Benzolactone Class of ATPase Inhibitors from the Myxobacterium Byssovorax cruentaAntibiotics from gliding bacteria, 105. Part 104: B. Kunze, H. Steinmetz, G. Höfle, H. Reichenbach J. Antibiot., submitted.
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- European Journal of Organic Chemistry, 2006, v. 2006, n. 22, p. 5036, doi. 10.1002/ejoc.200600421
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Spirangien A and B, Highly Cytotoxic and Antifungal Spiroketals from the Myxobacterium Sorangium cellulosum: Isolation, Structure Elucidation and Chemical ModificationsAntibiotics from Gliding Bacteria, 103. Part 102: Ref.1.
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- European Journal of Organic Chemistry, 2005, v. 2005, n. 23, p. 5013, doi. 10.1002/ejoc.200500425
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- Article
Tuscolid and Tuscoron A and B: Isolation, Structural Elucidation and Studies on the Biosynthesis of Novel Furan-3(2H)-one-Containing Metabolites from the Myxobacterium Sorangium Cellulosum.
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- European Journal of Organic Chemistry, 2004, v. 2004, n. 3, p. 487, doi. 10.1002/ejoc.200300539
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Cyrmenins, Novel Antifungal Peptides Containing a Nitrogen-Linked β-Methoxyacrylate Pharmacophore: Isolation and Structural Elucidation.
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- European Journal of Organic Chemistry, 2004, v. 2004, n. 2, p. 431, doi. 10.1002/ejoc.200300367
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- Article
Chondrochloren A and B, New β-Amino Styrenes from Chondromyces crocatus (Myxobacteria).
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- European Journal of Organic Chemistry, 2003, v. 2003, n. 14, p. 2684, doi. 10.1002/ejoc.200200699
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Chemical Modification of Thiangazole A in the Oxazole and Styryl Region.
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- European Journal of Organic Chemistry, 1999, v. 1999, n. 12, p. 3381, doi. 10.1002/(SICI)1099-0690(199912)1999:12<3381::AID-EJOC3381>3.0.CO;2-W
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Antibiotika aus Gleitenden Bakterien, XVII. Myxopyronin A und B - zwei neue Antibiotika aus Myxococcus fulvus Stamm Mx f50.
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- European Journal of Organic Chemistry, 1983, v. 1983, n. 10, p. 1656, doi. 10.1002/jlac.198319831003
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- Article
Corrigendum: Isolation and Total Synthesis of Icumazoles and Noricumazoles-Antifungal Antibiotics and Cation-Channel Blockers from Sorangium cellulosum.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 25, p. 6035, doi. 10.1002/anie.201201953
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Pellasoren: Structure Elucidation, Biosynthesis, and Total Synthesis of a Cytotoxic Secondary Metabolite from Sorangium cellulosum.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 21, p. 5239, doi. 10.1002/anie.201200327
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- Article
Isolation and Total Synthesis of Icumazoles and Noricumazoles-Antifungal Antibiotics and Cation-Channel Blockers from Sorangium cellulosum.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 5, p. 1256, doi. 10.1002/anie.201106435
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- Article
Molecular Basis of Elansolid Biosynthesis: Evidence for an Unprecedented Quinone Methide Initiated Intramolecular Diels-Alder Cycloaddition/Macrolactonization.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 17, p. 3882, doi. 10.1002/anie.201006880
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- Article
Gephyronic Acid, a Missing Link between Polyketide Inhibitors of Eukaryotic Protein Synthesis (Part I): Structural Revision and Stereochemical Assignment of Gephyronic Acid.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 4, p. 938, doi. 10.1002/anie.201005530
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Gephyronic Acid, a Missing Link between Polyketide Inhibitors of Eukaryotic Protein Synthesis (Part II): Total Synthesis of Gephyronic Acid.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 4, p. 942, doi. 10.1002/anie.201005605
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- Article
Chlorotonil A, a Macrolide with a Unique gem-Dichloro-1,3-dione Functionality from Sorangium cellulosum, So ce1525.
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- Angewandte Chemie International Edition, 2008, v. 47, n. 3, p. 600, doi. 10.1002/anie.200703993
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- Article
Isolation, Biological Activity Evaluation, Structure Elucidation, and Total Synthesis of Eliamid: A Novel Complex I Inhibitor.
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- Chemistry - A European Journal, 2012, v. 18, n. 36, p. 11362, doi. 10.1002/chem.201201879
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Back Cover: Isolation, Biological Activity Evaluation, Structure Elucidation, and Total Synthesis of Eliamid: A Novel Complex I Inhibitor (Chem. Eur. J. 36/2012).
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- Chemistry - A European Journal, 2012, v. 18, n. 36, p. 11476, doi. 10.1002/chem.201290157
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Sulfangolids, Macrolide Sulfate Esters from Sorangium cellulosum.
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- Chemistry - A European Journal, 2012, v. 18, n. 20, p. 6264, doi. 10.1002/chem.201100851
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- Article
Maracin and Maracen: New Types of Ethynyl Vinyl Ether and α-Chloro Divinyl Ether Antibiotics from Sorangium cellulosum with Specific Activity Against Mycobacteria.
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- Angewandte Chemie International Edition, 1998, v. 37, n. 9, p. 1253, doi. 10.1002/(SICI)1521-3773(19980518)37:9<1253::AID-ANIE1253>3.0.CO;2-T
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Epothilone A and B-Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution.
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- Angewandte Chemie International Edition, 1996, v. 35, n. 13/14, p. 1567, doi. 10.1002/anie.199615671
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Keronopsins A and B, Chemical Defence Substances of the Marine Ciliate Pseudokeronopsis rubra (Protozoa): Identification by Ex Vivo HPLC.
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- Angewandte Chemie International Edition, 1994, v. 33, n. 14, p. 1495, doi. 10.1002/anie.199414951
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Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 34, p. 10113, doi. 10.1002/anie.201603288
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- Article
Lange gesucht - die bioaktive Konformation von Epothilon und seine Bindung im Tubulin.
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- Angewandte Chemie, 2005, v. 117, n. 9, p. 1324, doi. 10.1002/ange.200462241
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Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from MyxobacteriaAntibiotics from Gliding Bacteria, Part 100; for Part 99, see: B. Kunze, R. Jansen, G. Höfle, H. Reichenbach, J. Antibiot.2004, 57, 151–155. We thank I. Schleicher, K. Schober, S. Reinecke, A. Ritter, and B. Hinkelmann for technical assistance, Dr. A. Ross and colleagues at the bio-pilotplant of the GBF for help with fermentations, Dr. V. Wray and colleagues for recording NMR and mass spectra, and Dr. H.-J. Hecht for generating stereopictures. We also thank Prof. G. R. Pettit for a generous gift of dolastatin 10. This work was supported by Morphochem AG and the Fonds der Chemischen Industrie.
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- Angewandte Chemie, 2004, v. 116, n. 37, p. 4996, doi. 10.1002/ange.200460147
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Komplexe Biosynthese in Myxobakterien: Bildung der Leupyrrine in SorangiumcellulosumDie Autoren danken Dr. V. Wray und Mitarbeitern der Abteilung Strukturaufklärung der GBF für die Aufnahme der NMR-Spektren sowie Prof. H. G. Floss...
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- Angewandte Chemie, 2004, v. 116, n. 32, p. 4257, doi. 10.1002/ange.200454240
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- Article
N-Imidoylisocyanide.
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- Angewandte Chemie, 1977, v. 89, n. 10, p. 742, doi. 10.1002/ange.19770891014
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Berichtigung: Isolierung und Totalsynthese der Icumazole und Noricumazole - antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum.
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- Angewandte Chemie, 2012, v. 124, n. 25, p. 6140, doi. 10.1002/ange.201201953
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Pellasoren: Struktur, Biosynthese und Totalsynthese eines zytotoxischen Sekundärmetaboliten aus Sorangium cellulosum.
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- Angewandte Chemie, 2012, v. 124, n. 21, p. 5330, doi. 10.1002/ange.201200327
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- Article
Isolierung und Totalsynthese der Icumazole und Noricumazole - antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum.
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- Angewandte Chemie, 2012, v. 124, n. 5, p. 1282, doi. 10.1002/ange.201106435
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- Article
Molekulare Grundlage für die Biosynthese von Elansolid: Beweise für eine einzigartige, durch ein Chinonmethid initiierte intramolekulare Diels-Alder-Cycloaddition/Makrolactonisierung.
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- Angewandte Chemie, 2011, v. 123, n. 17, p. 3968, doi. 10.1002/ange.201006880
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- Article
Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid- Inhibitoren der eukaryotischen Proteinsynthese (Teil I): Strukturrevision und stereochemische Zuordnung.
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- Angewandte Chemie, 2011, v. 123, n. 4, p. 968, doi. 10.1002/ange.201005530
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- Publication type:
- Article
Gephyronsäure, ein fehlendes Bindeglied zwischen Polyketid-Inhibitoren der eukaryotischen Proteinsynthese (Teil II): Totalsynthese.
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- Angewandte Chemie, 2011, v. 123, n. 4, p. 972, doi. 10.1002/ange.201005605
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- Article
4-Dialkylaminopyridines as Highly Active Acylation Catalysts. [New synthetic method (25)].
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- Angewandte Chemie International Edition, 1978, v. 17, n. 8, p. 569, doi. 10.1002/anie.197805691
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N-Imidoyl Isocyanides.
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- Angewandte Chemie International Edition, 1977, v. 16, n. 10, p. 727, doi. 10.1002/anie.197707271
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N-Acyl Isocyanides.
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- Angewandte Chemie International Edition, 1977, v. 16, n. 4, p. 262, doi. 10.1002/anie.197702621
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Oxidation of 5-Aminotetraazoles, a New Route to Isocyanides.
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- Angewandte Chemie International Edition, 1976, v. 15, n. 2, p. 113, doi. 10.1002/anie.197601131
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- Article
Hetero Cope Rearrangements in the Cyclization of Allyl and Propargyl Esters of N-Acyl Amino Acids to Oxazolin-5-ones.
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- Angewandte Chemie International Edition, 1975, v. 14, n. 1, p. 58, doi. 10.1002/anie.197500581
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- Article
α-Acyloxy Isocyanides (' O-Acyl Isocyanohydrins').
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- Angewandte Chemie International Edition, 1974, v. 13, n. 10, p. 676, doi. 10.1002/anie.197406761
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- Article
4-(Dialkylamino)quinolines and 3,3-Disubstituted 4(3 H)-Quinolones from 4 H-3,1-Benzoxazinones and Ynamines.
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- Angewandte Chemie International Edition, 1972, v. 11, n. 8, p. 720, doi. 10.1002/anie.197207201
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- Article
Base-Catalyzed Addition of Oxazol-5-ones to Activated Multiple Bonds.
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- Angewandte Chemie International Edition, 1971, v. 10, n. 9, p. 653, doi. 10.1002/anie.197106532
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- Article
Thuggacins, Macrolide Antibiotics Active against Mycobacterium tuberculosis: Isolation from Myxobacteria, Structure Elucidation, Conformation Analysis and Biosynthesis.
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- Chemistry - A European Journal, 2007, v. 13, n. 20, p. 5822, doi. 10.1002/chem.200700269
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- Article
Discovery and Development of the Epothilones: A Novel Class of Antineoplastic Drugs.
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- Drugs in R&D, 2008, v. 9, n. 1, p. 1, doi. 10.2165/00126839-200809010-00001
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- Article
Isolation and structure elucidation of the nucleoside antibiotic strepturidin from Streptomyces albus DSM 40763.
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- Journal of Antibiotics, 2014, v. 67, n. 6, p. 471, doi. 10.1038/ja.2014.16
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- Article
Pedein A and B: Production, Isolation, Structure Elucidation and Biological Properties of New Antifungal Cyclopeptides from Chondromyces pediculatus (Myxobacteria).
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- Journal of Antibiotics, 2008, v. 61, n. 1, p. 18, doi. 10.1038/ja.2008.4
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- Article
The Thuggacins, Novel Antibacterial Macrolides from Sorangium cellulosum Acting against Selected Gram-positive Bacteria.
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- Journal of Antibiotics, 2007, v. 60, n. 12, p. 733, doi. 10.1038/ja.2007.95
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- Publication type:
- Article
Cruentaren, a New Antifungal Salicylate-Type Macrolide from Byssovorax cruenta (Myxobacteria) with Inhibitory Effect on Mitochondrial ATPase Activity.
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- Journal of Antibiotics, 2006, v. 59, n. 10, p. 664, doi. 10.1038/ja.2006.89
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- Article
Aurafuron A and B, New Bioactive Polyketides from Stigmatella aurantiaca and Archangium gephyra (Myxobacteria).
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- Journal of Antibiotics, 2005, v. 58, n. 4, p. 244, doi. 10.1038/ja.2005.28
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- Article
Structure and Biosynthesis of Myxochromides S1–3 in Stigmatella aurantiaca: Evidence for an Iterative Bacterial Type I Polyketide Synthase and for Module Skipping in Nonribosomal Peptide BiosynthesisAntibiotics from Gliding Bacteria, Part 101; for Part 100 see: ref. 1.
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- ChemBioChem, 2005, v. 6, n. 2, p. 375, doi. 10.1002/cbic.200400282
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- Article
Much Anticipated-The Bioactive Conformation of Epothilone and Its Binding to Tubulin.
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 9, p. 1298, doi. 10.1002/anie.200462241
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- Publication type:
- Article
Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from MyxobacteriaAntibiotics from Gliding Bacteria, Part 100; for Part 99, see: B. Kunze, R. Jansen, G. Höfle, H. Reichenbach, J. Antibiot.2004, 57, 151–155. We thank I. Schleicher, K. Schober, S. Reinecke, A. Ritter, and B. Hinkelmann for technical assistance, Dr. A. Ross and colleagues at the bio-pilotplant of the GBF for help with fermentations, Dr. V. Wray and colleagues for recording NMR and mass spectra, and Dr. H.-J. Hecht for generating stereopictures. We also thank Prof. G. R. Pettit for a generous gift of dolastatin 10. This work was supported by Morphochem AG and the Fonds der Chemischen Industrie.
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 37, p. 4888, doi. 10.1002/anie.200460147
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- Article