Found: 70
Select item for more details and to access through your institution.
Evaluation of smartphone-based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial.
- Published in:
- 2018
- By:
- Publication type:
- journal article
First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Anti-Amyloid-β Immunotherapy in Alzheimer's Disease: ACC-001 Clinical Trials Are Ongoing.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 17, n. 2, p. 243, doi. 10.3233/JAD-2009-1118
- By:
- Publication type:
- Article
Effects of Rofecoxib or Naproxen vs Placebo on Alzheimer Disease Progression: A Randomized Controlled Trial.
- Published in:
- JAMA: Journal of the American Medical Association, 2003, v. 289, n. 21, p. 2819, doi. 10.1001/jama.289.21.2819
- By:
- Publication type:
- Article
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter.
- Published in:
- 2023
- By:
- Publication type:
- Abstract
Single-Photon Emission Computed Tomography in Human Immunodeficiency Virus Encephalopathy: A Preliminary Report.
- Published in:
- Journal of Nuclear Medicine, 1991, v. 32, n. 8, p. 1471
- By:
- Publication type:
- Article
Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6251, doi. 10.3390/ijms24076251
- By:
- Publication type:
- Article
Progress in the Active Immunotherapeutic Approach to Alzheimer’s Disease: Clinical Investigations into AN1792-Associated Meningoencephalitis.
- Published in:
- Neurodegenerative Diseases, 2008, v. 5, n. 3/4, p. 194, doi. 10.1159/000113700
- By:
- Publication type:
- Article
Aβ Immunotherapy: Lessons Learned for Potential Treatment of Alzheimer’s Disease.
- Published in:
- Neurodegenerative Diseases, 2005, v. 2, n. 5, p. 255, doi. 10.1159/000090365
- By:
- Publication type:
- Article
A phase 1 clinical trial of the sigma‐2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 20, doi. 10.1016/j.trci.2018.11.001
- By:
- Publication type:
- Article
A randomized, single ascending dose study of intravenous BIIB092 in healthy participants.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2018, v. 4, n. 1, p. 746, doi. 10.1016/j.trci.2018.10.007
- By:
- Publication type:
- Article
Understanding the relative importance of preserving functional abilities in Alzheimer's disease in the United States and Germany.
- Published in:
- Quality of Life Research, 2014, v. 23, n. 6, p. 1813, doi. 10.1007/s11136-013-0620-5
- By:
- Publication type:
- Article
P4‐708: CLINICAL BIOMARKER EVIDENCE FOR TARGET ENGAGEMENT, REDUCTION OF SYNAPTIC DAMAGE AND DISEASE MODIFICATION IN ALZHEIMER'S PATIENTS TREATED WITH CT1812.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1603, doi. 10.1016/j.jalz.2019.09.072
- By:
- Publication type:
- Article
P1‐051: PARTICIPANT BASELINE CHARACTERISTICS IN PASSPORT, A PHASE 2 STUDY OF THE EFFICACY AND SAFETY OF BIIB092 FOR PROGRESSIVE SUPRANUCLEAR PALSY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P252, doi. 10.1016/j.jalz.2019.06.076
- By:
- Publication type:
- Article
P3‐033: RANDOMIZED, DOUBLE‐BLIND, PLACEBO‐CONTROLLED STUDY TO ASSESS TREATMENT OF BIIB092 IN SUBJECTS WITH EARLY ALZHEIMER'S DISEASE: TANGO PHASE 2 STUDY DESIGN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1077, doi. 10.1016/j.jalz.2018.06.1388
- By:
- Publication type:
- Article
A PHASE 1 SAFETY TRIAL OF THE Aβ OLIGOMER RECEPTOR ANTAGONIST CT1812.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1570, doi. 10.1016/j.jalz.2017.07.730
- By:
- Publication type:
- Article
A TWO-PART, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 1 STUDY OF THE SAFETY AND PHARMACOKINETICS OF SINGLE AND MULTIPLE ASCENDING DOSES OF CT1812 IN HEALTHY VOLUNTEERS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1183, doi. 10.1016/j.jalz.2016.07.127
- By:
- Publication type:
- Article
Discovery, preclinical development, and clinical trial approach for npt088, a general amyloid interaction motif (GAIM)-immunoglobulin fusion.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P135, doi. 10.1016/j.jalz.2015.07.051
- By:
- Publication type:
- Article
A randomized, controlled, multicenter, international study of the impact of florbetapir (18F) PET amyloid imaging on patient management and outcome.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P334, doi. 10.1016/j.jalz.2015.08.159
- By:
- Publication type:
- Article
Assessing cognition and function in Alzheimer's disease clinical trials: Do we have the right tools?
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, n. 6, p. 853, doi. 10.1016/j.jalz.2014.07.158
- By:
- Publication type:
- Article
Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. 4, p. 438, doi. 10.1016/j.jalz.2013.03.007
- By:
- Publication type:
- Article
Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer’s disease clinical trials
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. s1, p. S45, doi. 10.1016/j.jalz.2011.11.002
- By:
- Publication type:
- Article
The ADAS-Cog revisited: Novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. s1, p. S21, doi. 10.1016/j.jalz.2012.05.2187
- By:
- Publication type:
- Article
Improving Alzheimer’s disease phase II clinical trials
- Published in:
- 2013
- By:
- Publication type:
- Editorial
Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2011, v. 7, n. 4, p. 367, doi. 10.1016/j.jalz.2011.05.2351
- By:
- Publication type:
- Article
Longitudinal changes in functional disability in Alzheimer's disease patients
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Immunotherapy with bapineuzumab lowers CSF tau protein levels in patients with Alzheimer's disease
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2010, v. 6, n. 2, p. 89, doi. 10.1016/j.jalz.2010.01.008
- By:
- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of bapineuzumab following multiple intravenous infusions in patients with mild-to-moderate Alzheimer's disease
- Published in:
- 2009
- By:
- Publication type:
- Abstract
Estimating dependence scale scores based on clinical dementia rating - sum of boxes scores in patients with mild cognitive impairment or mild to moderate Alzheimer's disease
- Published in:
- 2009
- By:
- Publication type:
- Abstract
Relationship between patient dependence on others and caregiver burden in Alzheimer's Disease (AD)
- Published in:
- 2009
- By:
- Publication type:
- Abstract
P3-137: The neuropsychological test battery discriminates patients with mild cognitive impairment from normal controls and Alzheimer's disease
- Published in:
- 2008
- By:
- Publication type:
- Abstract
O3-04-05: Clinical trials of bapineuzumab, a beta-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease
- Published in:
- 2008
- By:
- Publication type:
- Abstract
A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2008, v. 4, n. 3, p. 156, doi. 10.1016/j.jalz.2008.03.005
- By:
- Publication type:
- Article
A quarter century of advancing treatment for Alzheimer’s disease with Leon J. Thal
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2008, v. 4, n. 1, p. S51, doi. 10.1016/j.jalz.2007.11.006
- By:
- Publication type:
- Article
O2-05-04: Long term follow up of patients immunized with AN1792(QS-21): Reduced functional decline in antibody responders
- Published in:
- 2007
- By:
- Publication type:
- Abstract
P-002: The effect of individual characteristics on benefit-risk trade-offs for modifying the progression of Alzheimer’s disease
- Published in:
- 2007
- By:
- Publication type:
- Abstract
IC-P-096: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlations between serial MRI and conversion, genotype, and treatment status
- Published in:
- 2006
- By:
- Publication type:
- Abstract
IC-P-094: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlation between rates of change on MRI and cognitive/behavioral measures
- Published in:
- 2006
- By:
- Publication type:
- Abstract
IC-104-01: Regional distribution of grey matter changes in Abeta (AN1792) immunized patients with AD: A voxel-based morphometry analysis
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P2-186: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlations between serial MRI and conversion, genotype, and treatment status
- Published in:
- 2006
- By:
- Publication type:
- Abstract
O4-04-07: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlation between rates of change on MRI and cognitive/behavioral measures
- Published in:
- 2006
- By:
- Publication type:
- Abstract
IC-P-096: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlations between serial MRI and conversion, genotype, and treatment status
- Published in:
- 2006
- By:
- Publication type:
- Abstract
IC-P-094: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlation between rates of change on MRI and cognitive/behavioral measures
- Published in:
- 2006
- By:
- Publication type:
- Abstract
IC-104-01: Regional distribution of grey matter changes in Abeta (AN1792) immunized patients with AD: A voxel-based morphometry analysis
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P2-186: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlations between serial MRI and conversion, genotype, and treatment status
- Published in:
- 2006
- By:
- Publication type:
- Abstract
O4-04-07: Treatment of mild cognitive impairment with vitamin E and donepezil: Correlation between rates of change on MRI and cognitive/behavioral measures
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Alzheimer’s Association Research Roundtable Meeting on Mild Cognitive Impairment: What have we learned?
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2006, v. 2, n. 3, p. 220, doi. 10.1016/j.jalz.2006.04.010
- By:
- Publication type:
- Article
Donepezil and vitamin E in the progression of mild cognitive impairment to Alzheimer’s disease: A hazard-ratio analysis
- Published in:
- 2005
- By:
- Publication type:
- Abstract
Operational criteria for patient recruitment in trials of mild cognitive impairment
- Published in:
- 2005
- By:
- Publication type:
- Abstract