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The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
Published in:
EMBO Molecular Medicine, 2011, v. 3, n. 9, p. 545, doi. 10.1002/emmm.201100158
By:
- Cynis, Holger;
- Hoffmann, Torsten;
- Friedrich, Daniel;
- Kehlen, Astrid;
- Gans, Kathrin;
- Kleinschmidt, Martin;
- Rahfeld, Jens-Ulrich;
- Wolf, Raik;
- Wermann, Michael;
- Stephan, Anett;
- Haegele, Monique;
- Sedlmeier, Reinhard;
- Graubner, Sigrid;
- Jagla, Wolfgang;
- Müller, Anke;
- Eichentopf, Rico;
- Heiser, Ulrich;
- Seifert, Franziska;
- Quax, Paul H. A.;
- de Vries, Margreet R.
Publication type:
Article
Inhibition of Glutaminyl Cyclase: Pharmacology and steps towards clinical development
Published in:
2010
By:
- Demuth, Hans-Ulrich;
- Cynis, Holger;
- Alexandru, Anca;
- Jagla, Wolfgang;
- Graubner, Sigrid;
- Stephan v. Hoersten;
- Schilling, Stephan
Publication type:
Abstract
Distinct role of Glutaminyl Cyclases (QCs) in inflammation/neuroinflammation: First results from QC and isoQC knock out mice
Published in:
2010
By:
- Cynis, Holger;
- Graubner, Sigrid;
- Alexandru, Anca;
- Gans, Kathrin;
- Schilling, Stephan;
- Demuth, Hans-Ulrich
Publication type:
Abstract
Behavioral characterization of a new transgenic mouse model of pGlu-Aβ induced neurotoxicity: Automated, high-resolution, intra-home-cage and ethological-based phenotyping
Published in:
2009
By:
- Baeuscher, Christoph;
- Kohlmann, Stephanie;
- Graubner, Sigrid;
- Alexandru, Anca;
- Jagla, Wolfgang;
- Schilling, Stephan;
- von Hoersten, Stephan;
- Demuth, Hans-Ulrich
Publication type:
Abstract
Behavioral phenotyping of a new transgenic mouse model of pGlu-Aβ induced neurotoxicity: Classical behavioral approach
Published in:
2009
By:
- Kohlmann, Stephanie;
- Baeuscher, Christoph;
- Graubner, Sigrid;
- Alexandru, Anca;
- Jagla, Wolfgang;
- Schilling, Stephan;
- von Hörsten, Stephan;
- Demuth, Hans-Ulrich
Publication type:
Abstract
Association of neurotoxic Aβ-species and hippocampal cell loss with behavioral changes in TBA1 transgenic mice
Published in:
2009
By:
- Alexandru, Anca;
- Jagla, Wolfgang;
- Graubner, Sigrid;
- Bäuscher, Christoph;
- Kohlmann, Stephanie;
- Bayer, Thomas;
- Schilling, Stephan;
- Demuth, Hans-Ulrich;
- von Hörsten, Stephan
Publication type:
Abstract
Glutaminyl Cyclases as Novel Targets for the Treatment of Septic Arthritis.
Published in:
Journal of Infectious Diseases, 2013, v. 207, n. 5, p. 768, doi. 10.1093/infdis/jis729
By:
- Hellvard, Annelie;
- Maresz, Katarzyna;
- Schilling, Stephan;
- Graubner, Sigrid;
- Heiser, Ulrich;
- Jonsson, Roland;
- Cynis, Holger;
- Demuth, Hans-Ulrich;
- Potempa, Jan;
- Mydel, Piotr
Publication type:
Article
Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity.
Published in:
Biotechnology for Biofuels, 2017, v. 10, p. 1, doi. 10.1186/s13068-017-0928-4
By:
- Leis, Benedikt;
- Held, Claudia;
- Bergkemper, Fabian;
- Dennemarck, Katharina;
- Steinbauer, Robert;
- Reiter, Alarich;
- Mechelke, Matthias;
- Moerch, Matthias;
- Graubner, Sigrid;
- Liebl, Wolfgang;
- Schwarz, Wolfgang H.;
- Zverlov, Vladimir V.
Publication type:
Article
Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration.
Published in:
BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-108
By:
- Becker, Andreas;
- Kohlmann, Stephanie;
- Alexandru, Anca;
- Jagla, Wolfgang;
- Canneva, Fabio;
- Bäuscher, Christoph;
- Cynis, Holger;
- Sedlmeier, Reinhard;
- Graubner, Sigrid;
- Schilling, Stephan;
- Demuth, Hans-Ulrich;
- Hörsten, Stephan von
Publication type:
Article
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-?
Published in:
Nature, 2012, v. 485, n. 7400, p. 651, doi. 10.1038/nature11060
By:
- Nussbaum, Justin M.;
- Schilling, Stephan;
- Cynis, Holger;
- Silva, Antonia;
- Swanson, Eric;
- Wangsanut, Tanaporn;
- Tayler, Kaycie;
- Wiltgen, Brian;
- Hatami, Asa;
- Rönicke, Raik;
- Reymann, Klaus;
- Hutter-Paier, Birgit;
- Alexandru, Anca;
- Jagla, Wolfgang;
- Graubner, Sigrid;
- Glabe, Charles G.;
- Demuth, Hans-Ulrich;
- Bloom, George S.
Publication type:
Article
IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes.
Published in:
Biological Chemistry, 2016, v. 397, n. 1, p. 45, doi. 10.1515/hsz-2015-0192
By:
- Becker, Andreas;
- Eichentopf, Rico;
- Sedlmeier, Reinhard;
- Waniek, Alexander;
- Cynis, Holger;
- Koch, Birgit;
- Stephan, Anett;
- Bäuscher, Christoph;
- Kohlmann, Stephanie;
- Hoffmann, Torsten;
- Kehlen, Astrid;
- Berg, Sabine;
- Freyse, Ernst-Joachim;
- Osmand, Alexander;
- Plank, Anne-Christine;
- Roßner, Steffen;
- von Hörsten, Stephan;
- Graubner, Sigrid;
- Demuth, Hans-Ulrich;
- Schilling, Stephan
Publication type:
Article
Optimizing the composition of a synthetic cellulosome complex for the hydrolysis of softwood pulp: identification of the enzymatic core functions and biochemical complex characterization.
Published in:
Biotechnology for Biofuels, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13068-018-1220-y
By:
- Leis, Benedikt;
- Held, Claudia;
- Andreeßen, Björn;
- Liebl, Wolfgang;
- Graubner, Sigrid;
- Schulte, Louis-Philipp;
- Schwarz, Wolfgang H.;
- Zverlov, Vladimir V.
Publication type:
Article

Found: 12