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Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1446660
By:
- Berenguer, Jordi;
- Lagerweij, Tonny;
- Zhao, Xi Wen;
- Dusoswa, Sophie;
- van der Stoop, Petra;
- Westerman, Bart;
- Gooijer, Mark C. de;
- Zoetemelk, Marloes;
- Zomer, Anoek;
- Crommentuijn, Matheus H. W.;
- Wedekind, Laurine E.;
- López-López, Àlan;
- Giovanazzi, Alberta;
- Bruch-Oms, Marina;
- Meulen-Muileman, Ida H. van der;
- Reijmers, Rogier M.;
- van Kuppevelt, Toin H.;
- García-Vallejo, Juan-Jesús;
- van Kooyk, Yvette;
- Tannous, Bakhos A.
Publication type:
Article
Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1446660
By:
- Berenguer, Jordi;
- Lagerweij, Tonny;
- Zhao, Xi Wen;
- Dusoswa, Sophie;
- Van Der Stoop, Petra;
- Westerman, Bart;
- Gooijer, Mark C. De;
- Zoetemelk, Marloes;
- Zomer, Anoek;
- Crommentuijn, Matheus H. W.;
- Wedekind, Laurine E.;
- López-López, Àlan;
- Giovanazzi, Alberta;
- Bruch-Oms, Marina;
- Meulen-Muileman, Ida H. Van Der;
- Reijmers, Rogier M.;
- Van Kuppevelt, Toin H.;
- García-Vallejo, Juan-Jesús;
- Van Kooyk, Yvette;
- Tannous, Bakhos A.
Publication type:
Article
ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.
Published in:
Investigational New Drugs, 2018, v. 36, n. 3, p. 380, doi. 10.1007/s10637-017-0539-8
By:
- de Gooijer, Mark C.;
- Buil, Levi C. M.;
- Beijnen, Jos H.;
- van Tellingen, Olaf
Publication type:
Article
Comments on: "Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity".
Published in:
Neuro-Oncology, 2020, v. 22, n. 9, p. 1404, doi. 10.1093/neuonc/noaa112
By:
- Tellingen, Olaf van;
- Gooijer, Mark C de;
- Sarkaria, Jann N;
- Elmquist, William F
Publication type:
Article
MEK/MELK inhibition and blood–brain barrier deficiencies in atypical teratoid/rhabdoid tumors.
Published in:
Neuro-Oncology, 2020, v. 22, n. 1, p. 58, doi. 10.1093/neuonc/noz151
By:
- Meel, Michaël H;
- Navarro, Miriam Guillén;
- Gooijer, Mark C de;
- Metselaar, Dennis S;
- Waranecki, Piotr;
- Breur, Marjolein;
- Lagerweij, Tonny;
- Wedekind, Laurine E;
- Koster, Jan;
- Wetering, Marianne D van de;
- Meeteren, Netteke Schouten-van;
- Aronica, Eleonora;
- Tellingen, Olaf van;
- Bugiani, Marianna;
- Phoenix, Timothy N;
- Kaspers, Gertjan J L;
- Hulleman, Esther
Publication type:
Article
Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
Published in:
Neuro-Oncology, 2018, v. 20, n. 5, p. 642, doi. 10.1093/neuonc/nox198
By:
- Teng, Jian;
- Hejazi, Seyedali;
- Hiddingh, Lotte;
- Carvalho, Litia;
- Gooijer, Mark C de;
- Wakimoto, Hiroaki;
- Barazas, Marco;
- Tannous, Marie;
- Chi, Andrew S;
- Noske, David P
Publication type:
Article
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors.
Published in:
International Journal of Cancer, 2018, v. 142, n. 2, p. 381, doi. 10.1002/ijc.31052
By:
- de Gooijer, Mark C.;
- Zhang, Ping;
- Weijer, Ruud;
- Buil, Levi C. M.;
- Beijnen, Jos H.;
- van Tellingen, Olaf
Publication type:
Article
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.
Published in:
International Journal of Cancer, 2015, v. 137, n. 8, p. 2007, doi. 10.1002/ijc.29566
By:
- Zhang, Ping;
- de Gooijer, Mark C.;
- Buil, Levi C.M.;
- Beijnen, Jos H.;
- Li, Gang;
- van Tellingen, Olaf
Publication type:
Article
ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain.
Published in:
Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00562-4
By:
- Lentzas, Aristeidis;
- de Gooijer, Mark C.;
- Zuidema, Stefanie;
- Meurs, Amber;
- Çitirikkaya, Ceren H.;
- Venekamp, Nikkie;
- Beijnen, Jos H.;
- van Tellingen, Olaf
Publication type:
Article

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