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Inhibition of Aurora Kinase B Is Important for Biologic Activity of the Dual Inhibitors of BCR-ABL and Aurora Kinases R763/AS703569 and PHA-739358 in BCR-ABL Transformed Cells.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112318
By:
- Illert, Anna L.;
- Seitz, Anna K.;
- Rummelt, Christoph;
- Kreutmair, Stefanie;
- Engh, Richard A.;
- Goodstal, Samantha;
- Peschel, Christian;
- Duyster, Justus;
- von Bubnoff, Nikolas
Publication type:
Article
A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours.
Published in:
2019
By:
- de Weger, Vincent A.;
- de Jonge, Maja;
- Langenberg, Marlies H. G.;
- Schellens, Jan H. M.;
- Lolkema, Martijn;
- Varga, Andrea;
- Demers, Brigitte;
- Thomas, Koruth;
- Hsu, Karl;
- Tuffal, Gilles;
- Goodstal, Samantha;
- Macé, Sandrine;
- Deutsch, Eric
Publication type:
journal article
Selective Oral MEK1/2 Inhibitor Pimasertib in Metastatic Melanoma: Antitumor Activity in a Phase I, Dose-Escalation Trial.
Published in:
Targeted Oncology, 2021, v. 16, n. 1, p. 47, doi. 10.1007/s11523-020-00767-1
By:
- Lebbé, Céleste;
- Italiano, Antoine;
- Houédé, Nadine;
- Awada, Ahmad;
- Aftimos, Philippe;
- Lesimple, Thierry;
- Dinulescu, Monica;
- Schellens, Jan H. M.;
- Leijen, Suzanne;
- Rottey, Sylvie;
- Kruse, Vibeke;
- Kefford, Richard;
- Raymond, Eric;
- Faivre, Sandrine;
- Pages, Celine;
- Gomez-Roca, Carlos;
- Schueler, Armin;
- Goodstal, Samantha;
- Massimini, Giorgio;
- Delord, Jean-Pierre
Publication type:
Article
Preclinical evidence for the effective use of TL-895, a highly selective and potent second-generation BTK inhibitor, for the treatment of B-cell malignancies.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47735-z
By:
- Goodstal, Samantha M.;
- Lin, Jing;
- Crandall, Timothy;
- Crowley, Lindsey;
- Bender, Andrew T.;
- Pereira, Albertina;
- Soloviev, Maria;
- Wesolowski, John S.;
- Iadevaia, Riham;
- Schelhorn, Sven-Eric;
- Ross, Edith;
- Morandi, Federica;
- Ma, Jianguo;
- Clark, Anderson
Publication type:
Article

Found: 4

Inhibition of Aurora Kinase B Is Important for Biologic Activity of the Dual Inhibitors of BCR-ABL and Aurora Kinases R763/AS703569 and PHA-739358 in BCR-ABL Transformed Cells.

A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours.

Selective Oral MEK1/2 Inhibitor Pimasertib in Metastatic Melanoma: Antitumor Activity in a Phase I, Dose-Escalation Trial.

Preclinical evidence for the effective use of TL-895, a highly selective and potent second-generation BTK inhibitor, for the treatment of B-cell malignancies.