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Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32944-3
By:
- Jiang, Ying;
- Alam, John J.;
- Gomperts, Stephen N.;
- Maruff, Paul;
- Lemstra, Afina W.;
- Germann, Ursula A.;
- Stavrides, Philip H.;
- Darji, Sandipkumar;
- Malampati, Sandeep;
- Peddy, James;
- Bleiwas, Cynthia;
- Pawlik, Monika;
- Pensalfini, Anna;
- Yang, Dun-Sheng;
- Subbanna, Shivakumar;
- Basavarajappa, Balapal S.;
- Smiley, John F.;
- Gardner, Amanda;
- Blackburn, Kelly;
- Chu, Hui-May
Publication type:
Article
18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.
Published in:
2021
By:
- Goodheart, Anna E;
- Locascio, Joseph J;
- Samore, Wesley R;
- Collins, Jessica A;
- Brickhouse, Michael;
- Schultz, Aaron;
- Touroutoglou, Alexandra;
- Johnson, Keith A;
- Frosch, Matthew P;
- Growdon, John H;
- Dickerson, Bradford C;
- Gomperts, Stephen N
Publication type:
journal article
Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4234, doi. 10.1002/alz.13861
By:
- Moguilner, Sebastian G.;
- Berezuk, Courtney;
- Bender, Alex C.;
- Pellerin, Kyle R.;
- Gomperts, Stephen N.;
- Cash, Sydney S.;
- Sarkis, Rani A.;
- Lam, Alice D.
Publication type:
Article
Lewy body dementia: Overcoming barriers and identifying solutions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2298, doi. 10.1002/alz.13674
By:
- Agarwal, Kanishka;
- Backler, Wendi;
- Bayram, Ece;
- Bloom, Leah;
- Boeve, Bradley F.;
- Cha, Jang‐Ho;
- Denslow, Maria;
- Ferman, Tanis J.;
- Galasko, Douglas;
- Galvin, James E.;
- Gomperts, Stephen N.;
- Irizarry, Michael C.;
- Kantarci, Kejal;
- Kaushik, Harsh;
- Kietlinski, Matt;
- Koenig, Aaron;
- Leverenz, James B.;
- McKeith, Ian;
- McLean, Pamela J.;
- Montine, Thomas J.
Publication type:
Article
18F‐Flortaucipir PET imaging compared with autopsy in a clinically and pathologically heterogeneous group of patients with neurodegenerative dementias.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056305
By:
- McGinnis, Scott M.;
- Touroutoglou, Alexandra;
- Eckbo, Ryan;
- Brickhouse, Michael;
- Quimby, Megan;
- Wong, Bonnie;
- Frosch, Matthew P.;
- Gomperts, Stephen;
- Johnson, Keith A.;
- Dickerson, Brad C.
Publication type:
Article
Predictive value of visually rated tau PET imaging for amyloid status, atrophy, and syndromic diagnosis across a spectrum of neurodegenerative phenotypes: Neuroimaging / differential diagnosis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046761
By:
- McGinnis, Scott;
- Collins, Jessica A.;
- Eckbo, Ryan;
- Brickhouse, Michael;
- Gomperts, Stephen;
- Johnson, Keith A.;
- Dickerson, Brad C.
Publication type:
Article
P1‐359: TOPOGRAPHY OF CORTICAL THINNING IN THE LEWY BODY DEMENTIAS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P388, doi. 10.1016/j.jalz.2019.06.914
By:
- Ye, Rong;
- Touroutoglou, Alexandra;
- Brickhouse, Michael;
- Katz, Samantha;
- Johnson, Keith A.;
- Dickerson, Brad C.;
- Gomperts, Stephen
Publication type:
Article
IC‐P‐067: TOPOGRAPHY OF CORTICAL THINNING IN THE LEWY BODY DEMENTIAS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P63, doi. 10.1016/j.jalz.2019.06.4910
By:
- Ye, Rong;
- Touroutoglou, Alexandra;
- Brickhouse, Michael;
- Katz, Samantha;
- Johnson, Keith A.;
- Dickerson, Brad C.;
- Gomperts, Stephen
Publication type:
Article
O5‐03‐04: THE LEWY BODY DEMENTIA ASSOCIATION RESEARCH CENTERS OF EXCELLENCE PROGRAM: TOWARD OPTIMIZING CLINICAL CARE AND CLINICAL TRIAL INFRASTRUCTURE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1646, doi. 10.1016/j.jalz.2018.06.3010
By:
- Boeve, Bradley F.;
- Armstrong, Melissa;
- Galvin, James E.;
- Goldman, Jennifer;
- Irwin, David J.;
- Kaufer, Daniel;
- Leverenz, James B.;
- Lunde, Angela M.;
- McKeith, Ian G.;
- Paulson, Henry L.;
- Siderowf, Andrew D.;
- Barrett, Matthew J.;
- Kimiko, Domoto-Reilly;
- Duda, John;
- Galasko, Doug R.;
- Gomperts, Stephen;
- Graff-Radford, Neill R.;
- Holden, Samantha K.;
- Honig, Lawrence S.;
- Huddleston, Daniel
Publication type:
Article
VTA neurons coordinate with the hippocampal reactivation of spatial experience.
Published in:
eLife, 2015, p. 1, doi. 10.7554/eLife.05360
By:
- Gomperts, Stephen N.;
- Kloosterman, Fabian;
- Wilson, Matthew A.
Publication type:
Article
Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-25364-2
By:
- Zhou, Heng;
- Li, Hanyan;
- Gowravaram, Niket;
- Quan, Moqin;
- Kausar, Naila;
- Gomperts, Stephen N.
Publication type:
Article
Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.
Published in:
Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0476-1
By:
- Peterson, Bethany;
- Armstrong, Melissa;
- Galasko, Douglas;
- Galvin, James E.;
- Goldman, Jennifer;
- Irwin, David;
- Paulson, Henry;
- Kaufer, Daniel;
- Leverenz, James;
- Lunde, Angela;
- McKeith, Ian G.;
- Siderowf, Andrew;
- Taylor, Angela;
- Amodeo, Katherine;
- Barrett, Matt;
- Domoto-Reilly, Kimiko;
- Duda, John;
- Gomperts, Stephen;
- Graff-Radford, Neill;
- Holden, Samantha
Publication type:
Article
Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.
Published in:
Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2021.805135
By:
- Scott, Gregory D.;
- Arnold, Moriah R.;
- Beach, Thomas G.;
- Gibbons, Christopher H.;
- Kanthasamy, Anumantha G.;
- Lebovitz, Russell M.;
- Lemstra, Afina W.;
- Shaw, Leslie M.;
- Teunissen, Charlotte E.;
- Zetterberg, Henrik;
- Taylor, Angela S.;
- Graham, Todd C.;
- Boeve, Bradley F.;
- Gomperts, Stephen N.;
- Graff-Radford, Neill R.;
- Moussa, Charbel;
- Poston, Kathleen L.;
- Rosenthal, Liana S.;
- Sabbagh, Marwan N.;
- Walsh, Ryan R.
Publication type:
Article
Imaging the Role of Amyloid in PD Dementia and Dementia with Lewy Bodies.
Published in:
Current Neurology & Neuroscience Reports, 2014, v. 14, n. 8, p. 1, doi. 10.1007/s11910-014-0472-6
By:
- Gomperts, Stephen
Publication type:
Article
PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.
Published in:
Neurodegenerative Diseases, 2016, v. 16, n. 1/2, p. 118, doi. 10.1159/000441421
By:
- Gomperts, Stephen N.;
- Marquie, Marta;
- Locascio, Joseph J.;
- Bayer, Stephen;
- Johnson, Keith a.;
- Growdon, John H.
Publication type:
Article
Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0482-0
By:
- Marquié, Marta;
- Verwer, Eline E.;
- Meltzer, Avery C.;
- Ji Who Kim, Sally;
- Agüero, Cinthya;
- Gonzalez, Jose;
- Makaretz, Sara J.;
- Siao Tick Chong, Michael;
- Ramanan, Prianca;
- Amaral, Ana C.;
- Normandin, Marc D.;
- Vanderburg, Charles R.;
- Gomperts, Stephen N.;
- Johnson, Keith A.;
- Frosch, Matthew P.;
- Gómez-Isla, Teresa
Publication type:
Article
Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-73082-8
By:
- Zhao, Qiuchen;
- Yokomizo, Shinya;
- Perle, Stephen J.;
- Lee, Yee Fun;
- Zhou, Heng;
- Miller, Morgan R.;
- Li, Hanyan;
- Gerashchenko, Dmitry;
- Gomperts, Stephen N.;
- Bacskai, Brian J.;
- Kastanenka, Ksenia V.
Publication type:
Article
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease.
Published in:
Advanced Science, 2024, v. 11, n. 32, p. 1, doi. 10.1002/advs.202309021
By:
- Bai, Ping;
- Lan, Yu;
- Liu, Yan;
- Mondal, Prasenjit;
- Gomm, Ashley;
- Xu, Yulong;
- Wang, Yanli;
- Wang, Yongle;
- Kang, Leyi;
- Pan, Lili;
- Bagdasarian, Frederick A.;
- Hallisey, Madelyn;
- Lobo, Fleur;
- Varela, Breanna;
- Choi, Se Hoon;
- Gomperts, Stephen N.;
- Wey, Hsiao‐Ying;
- Shen, Shiqian;
- Tanzi, Rudolph E.;
- Wang, Changning
Publication type:
Article
Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.
Published in:
JAMA Neurology, 2017, v. 74, n. 4, p. 427, doi. 10.1001/jamaneurol.2016.5755
By:
- Chenjie Xia;
- Makaretz, Sara J.;
- Caso, Christina;
- McGinnis, Scott;
- Gomperts, Stephen N.;
- Sepulcre, Jorge;
- Gomez-Isla, Teresa;
- Hyman, Bradley T.;
- Schultz, Aaron;
- Vasdev, Neil;
- Johnson, Keith A.;
- Dickerson, Bradford C.
Publication type:
Article
Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.
Published in:
JAMA Neurology, 2016, v. 73, n. 11, p. 1334, doi. 10.1001/jamaneurol.2016.3338
By:
- Gomperts, Stephen N.;
- Locascio, Joseph J.;
- Makaretz, Sara J.;
- Schultz, Aaron;
- Caso, Christina;
- Vasdev, Neil;
- Sperling, Reisa;
- Growdon, John H.;
- Dickerson, Bradford C.;
- Johnson, Keith
Publication type:
Article
Cellular resolution contributions to ictal population signals.
Published in:
Epilepsia (Series 4), 2024, v. 65, n. 7, p. 2165, doi. 10.1111/epi.17983
By:
- Lau, Lauren A.;
- Zhao, Zhuoyang;
- Gomperts, Stephen N.;
- Staley, Kevin J.;
- Lillis, Kyle P.
Publication type:
Article
Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an 11C altropane positron emission tomography study.
Published in:
Alzheimer's Research & Therapy, 2014, v. 6, n. 8, p. 1, doi. 10.1186/s13195-014-0052-7
By:
- Marquie, Marta;
- Locascio, Joseph J.;
- Rentz, Dorene M.;
- Becker, J. Alex;
- Hedden, Trey;
- Johnson, Keith A.;
- Growdon, John H.;
- Gomperts, Stephen N.
Publication type:
Article
18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.
Published in:
2017
By:
- Schonhaut, Daniel R.;
- McMillan, Corey T.;
- Spina, Salvatore;
- Dickerson, Bradford C.;
- Siderowf, Andrew;
- Devous, Michael D.;
- Tsai, Richard;
- Winer, Joseph;
- Russell, David S.;
- Litvan, Irene;
- Roberson, Erik D.;
- Seeley, William W.;
- Grinberg, Lea T.;
- Kramer, Joel H.;
- Miller, Bruce L.;
- Pressman, Peter;
- Nasrallah, Ilya;
- Baker, Suzanne L.;
- Gomperts, Stephen N.;
- Johnson, Keith A.
Publication type:
journal article
Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies.
Published in:
2017
By:
- Marquié, Marta;
- Normandin, Marc D.;
- Meltzer, Avery C.;
- Siao Tick Chong, Michael;
- Andrea, Nicolas V.;
- Antón‐Fernández, Alejandro;
- Klunk, William E.;
- Mathis, Chester A.;
- Ikonomovic, Milos D.;
- Debnath, Manik;
- Bien, Elizabeth A.;
- Vanderburg, Charles R.;
- Costantino, Isabel;
- Makaretz, Sara;
- DeVos, Sarah L.;
- Oakley, Derek H.;
- Gomperts, Stephen N.;
- Growdon, John H.;
- Domoto‐Reilly, Kimiko;
- Lucente, Diane
Publication type:
journal article
Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.
Published in:
2015
By:
- Marquié, Marta;
- Normandin, Marc D.;
- Vanderburg, Charles R.;
- Costantino, Isabel M.;
- Bien, Elizabeth A.;
- Rycyna, Lisa G.;
- Klunk, William E.;
- Mathis, Chester A.;
- Ikonomovic, Milos D.;
- Debnath, Manik L.;
- Vasdev, Neil;
- Dickerson, Bradford C.;
- Gomperts, Stephen N.;
- Growdon, John H.;
- Johnson, Keith A.;
- Frosch, Matthew P.;
- Hyman, Bradley T.;
- Gómez‐Isla, Teresa
Publication type:
journal article
Clearing the Smoke: What Protects Smokers from Parkinson's Disease?
Published in:
Movement Disorders, 2024, v. 39, n. 2, p. 267, doi. 10.1002/mds.29707
By:
- Rose, Kenneth N.;
- Schwarzschild, Michael A.;
- Gomperts, Stephen N.
Publication type:
Article
Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.
Published in:
Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00682-9
By:
- Zhao, Qiuchen;
- Maci, Megi;
- Miller, Morgan R.;
- Zhou, Heng;
- Zhang, Fang;
- Algamal, Moustafa;
- Lee, Yee Fun;
- Hou, Steven S.;
- Perle, Stephen J.;
- Le, Hoang;
- Russ, Alyssa N.;
- Lo, Eng H.;
- Gerashchenko, Dmitry;
- Gomperts, Stephen N.;
- Bacskai, Brian J.;
- Kastanenka, Ksenia V.
Publication type:
Article
Reply: Beyond the limits of detection: failure of PiB imaging to capture true Aβ burden.
Published in:
2013
By:
- Gomperts, Stephen N;
- Johnson, Keith A;
- Growdon, John
Publication type:
Letter
Reply: Beyond the limits of detection: Failure of PiB imaging to capture true Aβ burden.
Published in:
Movement Disorders, 2013, v. 28, n. 3, p. 407, doi. 10.1002/mds.25309
By:
- Gomperts, Stephen N.;
- Johnson, Keith A.;
- Growdon, John
Publication type:
Article
Brain amyloid and cognition in Lewy body diseases.
Published in:
Movement Disorders, 2012, v. 27, n. 8, p. 965, doi. 10.1002/mds.25048
By:
- Gomperts, Stephen N.;
- Locascio, Joseph J.;
- Marquie, Marta;
- Santarlasci, Andrea L.;
- Rentz, Dorene M.;
- Maye, Jacqueline;
- Johnson, Keith A.;
- Growdon, John H.
Publication type:
Article
Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40402-3
By:
- Lee, Yee Fun;
- Russ, Alyssa N.;
- Zhao, Qiuchen;
- Perle, Stephen J.;
- Maci, Megi;
- Miller, Morgan R.;
- Hou, Steven S.;
- Algamal, Moustafa;
- Zhao, Zhuoyang;
- Li, Hanyan;
- Gelwan, Noah;
- Liu, Zhe;
- Gomperts, Stephen N.;
- Araque, Alfonso;
- Galea, Elena;
- Bacskai, Brian J.;
- Kastanenka, Ksenia V.
Publication type:
Article
Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40402-3
By:
- Lee, Yee Fun;
- Russ, Alyssa N.;
- Zhao, Qiuchen;
- Perle, Stephen J.;
- Maci, Megi;
- Miller, Morgan R.;
- Hou, Steven S.;
- Algamal, Moustafa;
- Zhao, Zhuoyang;
- Li, Hanyan;
- Gelwan, Noah;
- Liu, Zhe;
- Gomperts, Stephen N.;
- Araque, Alfonso;
- Galea, Elena;
- Bacskai, Brian J.;
- Kastanenka, Ksenia V.
Publication type:
Article

Found: 32

Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.

18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.

Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.

Lewy body dementia: Overcoming barriers and identifying solutions.

18F‐Flortaucipir PET imaging compared with autopsy in a clinically and pathologically heterogeneous group of patients with neurodegenerative dementias.

Predictive value of visually rated tau PET imaging for amyloid status, atrophy, and syndromic diagnosis across a spectrum of neurodegenerative phenotypes: Neuroimaging / differential diagnosis.

P1‐359: TOPOGRAPHY OF CORTICAL THINNING IN THE LEWY BODY DEMENTIAS.

IC‐P‐067: TOPOGRAPHY OF CORTICAL THINNING IN THE LEWY BODY DEMENTIAS.

O5‐03‐04: THE LEWY BODY DEMENTIA ASSOCIATION RESEARCH CENTERS OF EXCELLENCE PROGRAM: TOWARD OPTIMIZING CLINICAL CARE AND CLINICAL TRIAL INFRASTRUCTURE.

VTA neurons coordinate with the hippocampal reactivation of spatial experience.

Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease.

Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.

Imaging the Role of Amyloid in PD Dementia and Dementia with Lewy Bodies.

PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.

Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case.

Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model.

Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease.

Association of In Vivo [<sup>18</sup>F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.

Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.

Cellular resolution contributions to ictal population signals.

Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an <sup>11</sup>C altropane positron emission tomography study.

<sup>18</sup> F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.

Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies.

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.

Clearing the Smoke: What Protects Smokers from Parkinson's Disease?

Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.

Reply: Beyond the limits of detection: failure of PiB imaging to capture true Aβ burden.

Reply: Beyond the limits of detection: Failure of PiB imaging to capture true Aβ burden.

Brain amyloid and cognition in Lewy body diseases.

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.