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Opposing effects of inhibitors of aurora-A and EGFR in autosomal-dominant polycystic kidney disease.
- Published in:
- Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00228
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- Publication type:
- Article
Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel-Lindau protein.
- Published in:
- EMBO Journal, 2003, v. 22, n. 16, p. 4249, doi. 10.1093/emboj/cdg410
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- Publication type:
- Article
A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1.
- Published in:
- EMBO Journal, 2000, v. 19, n. 24, p. 6759, doi. 10.1093/emboj/19.24.6759
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- Publication type:
- Article
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer.
- Published in:
- Breast Cancer Research & Treatment, 2019, v. 177, n. 2, p. 369, doi. 10.1007/s10549-019-05329-2
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- Publication type:
- Article
Matrix-regulated integrin α<sub>v</sub>β<sub>5</sub> maintains α<sub>5</sub>β<sub>1</sub>-dependent desmoplastic traits prognostic of neoplastic recurrence.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.20600
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- Publication type:
- Article
Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29227-2
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- Publication type:
- Article
A new strategy to ERADicate HER2-positive breast tumors?
- Published in:
- Science Signaling, 2015, v. 8, n. 378, p. 1, doi. 10.1126/scisignal.aac4746
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- Publication type:
- Article
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle.
- Published in:
- Cell Biochemistry & Biophysics, 2007, v. 48, n. 1, p. 54, doi. 10.1007/s12013-007-0036-3
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- Publication type:
- Article
A ciliary timer for S-phase entry.
- Published in:
- 2007
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- Publication type:
- Letter
A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer.
- Published in:
- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144126
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- Publication type:
- Article
Inhibiting Heat Shock Protein 90 (HSP90) Limits the Formation of Liver Cysts Induced by Conditional Deletion of Pkd1 in Mice.
- Published in:
- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114403
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- Publication type:
- Article
The Centrosomal Kinase Plk1 Localizes to the Transition Zone of Primary Cilia and Induces Phosphorylation of Nephrocystin-1.
- Published in:
- PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038838
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- Publication type:
- Article
NEDD9 and BCAR1 Negatively Regulate E-Cadherin Membrane Localization, and Promote E-Cadherin Degradation.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022102
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- Publication type:
- Article
Dcas Supports Cell Polarization and Cell-Cell Adhesion Complexes in Development.
- Published in:
- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012369
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- Publication type:
- Article
Autoinhibited proteins as promising drug targets.
- Published in:
- Journal of Cellular Biochemistry, 2004, v. 93, n. 1, p. 68, doi. 10.1002/jcb.20184
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- Publication type:
- Article
Source, co-occurrence, and prognostic value of PTEN mutations or loss in colorectal cancer.
- Published in:
- NPJ Genomic Medicine, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41525-023-00384-7
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- Publication type:
- Article
Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11530-0
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- Publication type:
- Article
Targeting the Epidermal Growth Factor Receptor in EGFR-Mutated Lung Cancer: Current and Emerging Therapies.
- Published in:
- Cancers, 2021, v. 13, n. 13, p. 3164, doi. 10.3390/cancers13133164
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- Publication type:
- Article
Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer.
- Published in:
- Cancers, 2020, v. 12, n. 2, p. 306, doi. 10.3390/cancers12020306
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- Publication type:
- Article
Tumor-Targeted Drug Conjugates as an Emerging Novel Therapeutic Approach in Small Cell Lung Cancer (SCLC).
- Published in:
- Cancers, 2019, v. 11, n. 9, p. 1297, doi. 10.3390/cancers11091297
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- Publication type:
- Article
Prognostic role and biologic features of Musashi-2 expression in colon polyps and during colorectal cancer progression.
- Published in:
- PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0252132
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- Publication type:
- Article
The tumor suppressor FBW7 controls ciliary length.
- Published in:
- EMBO Journal, 2015, v. 34, n. 19, p. 2388, doi. 10.15252/embj.201592588
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- Publication type:
- Article
Control of ciliation in embryogenesis.
- Published in:
- Nature Cell Biology, 2015, v. 17, n. 2, p. 109, doi. 10.1038/ncb3103
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- Publication type:
- Article
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome.
- Published in:
- Nature Cell Biology, 2005, v. 7, n. 10, p. 937, doi. 10.1038/ncb1309
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- Publication type:
- Article
Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2.
- Published in:
- Oncogene, 1999, v. 18, n. 35, p. 4891, doi. 10.1038/sj.onc.1203080
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- Publication type:
- Article
Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II.
- Published in:
- Oncogene, 1998, v. 17, n. 5, p. 603, doi. 10.1038/sj.onc.1201964
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- Publication type:
- Article
Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22.
- Published in:
- Oncogene, 1997, v. 15, n. 9, p. 1043, doi. 10.1038/sj.onc.1201268
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- Publication type:
- Article
Intrapancreatic fat, pancreatitis, and pancreatic cancer.
- Published in:
- Cellular & Molecular Life Sciences, 2023, v. 80, n. 8, p. 1, doi. 10.1007/s00018-023-04855-z
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- Publication type:
- Article
The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.
- Published in:
- Cellular & Molecular Life Sciences, 2022, v. 79, n. 6, p. 1, doi. 10.1007/s00018-022-04321-2
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- Publication type:
- Article
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).
- Published in:
- FASEB Journal, 2018, v. 32, n. 5, p. 2735, doi. 10.1096/fj.201700909R
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- Publication type:
- Article
Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.
- Published in:
- BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09310-8
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- Publication type:
- Article
Correction: Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.
- Published in:
- 2023
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- Publication type:
- Correction Notice
Candidate variants in DNA replication and repair genes in early-onset renal cell carcinoma patients referred for germline testing.
- Published in:
- BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09310-8
- By:
- Publication type:
- Article
The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.
- Published in:
- Cell Division, 2010, v. 5, p. 22, doi. 10.1186/1747-1028-5-22
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- Publication type:
- Article
An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion.
- Published in:
- 2019
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- Publication type:
- journal article
Aurora A kinase activity influences calcium signaling in kidney cells.
- Published in:
- Journal of Cell Biology, 2011, v. 193, n. 6, p. 1021, doi. 10.1083/jcb.201012061
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- Publication type:
- Article
Interaction of germline variants in a family with a history of early‐onset clear cell renal cell carcinoma.
- Published in:
- Molecular Genetics & Genomic Medicine, 2019, v. 7, n. 3, p. N.PAG, doi. 10.1002/mgg3.556
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- Publication type:
- Article
Prevalence of pathogenic variants in DNA damage response and repair genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70449-5
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- Publication type:
- Article
Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation.
- Published in:
- Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00075
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- Publication type:
- Article
Mechanisms for nonmitotic activation of Aurora-A at cilia.
- Published in:
- Biochemical Society Transactions, 2017, v. 45, n. 1, p. 37, doi. 10.1042/BST20160142
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- Publication type:
- Article
The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies.
- Published in:
- Cellular & Molecular Life Sciences, 2013, v. 70, n. 11, p. 1849, doi. 10.1007/s00018-012-1052-z
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- Publication type:
- Article
Aurora A kinase (AURKA) in normal and pathological cell division.
- Published in:
- Cellular & Molecular Life Sciences, 2013, v. 70, n. 4, p. 661, doi. 10.1007/s00018-012-1073-7
- By:
- Publication type:
- Article
CAS proteins in normal and pathological cell growth control.
- Published in:
- Cellular & Molecular Life Sciences, 2010, v. 67, n. 7, p. 1025, doi. 10.1007/s00018-009-0213-1
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- Publication type:
- Article
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01877-7
- By:
- Publication type:
- Article
Head and neck squamous cell carcinoma: Ambiguous human papillomavirus status, elevated p16, and deleted retinoblastoma 1.
- Published in:
- Head & Neck, 2017, v. 39, n. 3, p. E34, doi. 10.1002/hed.24604
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- Publication type:
- Article
A gene expression system offering multiple levels of regulation: the Dual Drug Control (DDC) system.
- Published in:
- BMC Biotechnology, 2004, v. 4, p. 9, doi. 10.1186/1472-6750-4-9
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- Publication type:
- Article
CAS proteins in health and disease: An update.
- Published in:
- IUBMB Life, 2014, v. 66, n. 6, p. 387, doi. 10.1002/iub.1282
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- Publication type:
- Article
Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization.
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1415-6
- By:
- Publication type:
- Article
Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2022, v. 114, n. 12, p. 1619, doi. 10.1093/jnci/djac163
- By:
- Publication type:
- Article