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Case Report: Complete pathologic response to neoadjuvant selpercatinib in a patient with resectable early-stage RET fusion-positive non-small cell lung cancer.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1178313
By:
- Goldman, Jonathan W.;
- Sholl, Lynette M.;
- Dacic, Sanja;
- Fishbein, Michael C.;
- Murciano-Goroff, Yonina R.;
- Rajaram, Ravi;
- Szymczak, Sylwia;
- Szpurka, Anna M.;
- Chao, Bo H.;
- Drilon, Alexander
Publication type:
Article
Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.
Published in:
Investigational New Drugs, 2018, v. 36, n. 4, p. 629, doi. 10.1007/s10637-017-0532-2
By:
- Goldman, Jonathan W.;
- Rosen, Lee S.;
- Tolcher, Anthony W.;
- Papadopoulos, Kyriakos;
- Beeram, Muralidhar;
- Shi, Peipei;
- Pitou, Celine;
- Bell, Robert;
- Kulanthaivel, Palaniappan;
- Zhang, Xuekui;
- Fink, Aaron;
- Chan, Edward M.;
- Shahir, Ashwin;
- Farrington, Daphne;
- Patnaik, Amita
Publication type:
Article
Biomarker-Directed Phase II Platform Study in Patients With EGFR Sensitizing Mutation-Positive Advanced/Metastatic Non-Small Cell Lung Cancer Whose Disease Has Progressed on First-Line Osimertinib Therapy (ORCHARD).
Published in:
Clinical Lung Cancer, 2021, v. 22, n. 6, p. 601, doi. 10.1016/j.cllc.2021.06.006
By:
- Yu, Helena A.;
- Goldberg, Sarah B.;
- Le, Xiuning;
- Piotrowska, Zofia;
- Goldman, Jonathan W.;
- De Langen, Adrianus J.;
- Okamoto, Isamu;
- Cho, Byoung Chul;
- Smith, Paul;
- Mensi, Ilhem;
- Ambrose, Helen;
- Kraljevic, Silvija;
- Maidment, Julie;
- Chmielecki, Juliann;
- Li-Sucholeiki, Xiaocheng;
- Doughton, Gail;
- Patel, Gargi;
- Jewsbury, Phil;
- Szekeres, Phil;
- Riess, Jonathan W.
Publication type:
Article
Clinical Implications of the T790M Mutation in Disease Characteristics and Treatment Response in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small-Cell Lung Cancer (NSCLC).
Published in:
2018
By:
- Gaut, Daria;
- Myung Shin Sim;
- Yuguang Yue;
- Wolf, Brian R.;
- Abarca, Phillip A.;
- Carroll, James M.;
- Goldman, Jonathan W.;
- Garon, Edward B.;
- Sim, Myung Shin;
- Yue, Yuguang
Publication type:
journal article
Treatment Rationale and Study Design for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Patients With Stage IV Non-Small-Cell Lung Cancer With a Detectable KRAS Mutation Whose Disease Has Progressed After Platinum-Based Chemotherapy.
Published in:
2016
By:
- Goldman, Jonathan W.;
- Shi, Peipei;
- Reck, Martin;
- Paz-Ares, Luis;
- Koustenis, Andrew;
- Hurt, Karla C.
Publication type:
journal article
Diverse cutaneous adverse eruptions caused by anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) immunotherapies: clinical features and management.
Published in:
Therapeutic Advances in Medical Oncology, 2018, v. 10, n. 1, p. 1, doi. 10.1177/1758834017751634
By:
- Shen, John;
- Chang, Jason;
- Mendenhall, Melody;
- Cherry, Grace;
- Goldman, Jonathan W.;
- Kulkarni, Rajan P.
Publication type:
Article
Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.
Published in:
Nature Communications, 2016, v. 7, n. 11, p. 13513, doi. 10.1038/ncomms13513
By:
- Chabon, Jacob J.;
- Simmons, Andrew D.;
- Lovejoy, Alexander F.;
- Esfahani, Mohammad S.;
- Newman, Aaron M.;
- Haringsma, Henry J.;
- Kurtz, David M.;
- Stehr, Henning;
- Scherer, Florian;
- Karlovich, Chris A.;
- Harding, Thomas C.;
- Durkin, Kathleen A.;
- Otterson, Gregory A.;
- Thomas Purcell, W.;
- Ross Camidge, D.;
- Goldman, Jonathan W.;
- Sequist, Lecia V.;
- Piotrowska, Zofia;
- Wakelee, Heather A.;
- Neal, Joel W.
Publication type:
Article
Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.
Published in:
Nature Communications, 2016, v. 7, n. 6, p. 11815, doi. 10.1038/ncomms11815
By:
- Chabon, Jacob J.;
- Simmons, Andrew D.;
- Lovejoy, Alexander F.;
- Esfahani, Mohammad S.;
- Newman, Aaron M.;
- Haringsma, Henry J.;
- Kurtz, David M.;
- Stehr, Henning;
- Scherer, Florian;
- Karlovich, Chris A.;
- Harding, Thomas C.;
- Durkin, Kathleen A.;
- Otterson, Gregory A.;
- Purcell, W. Thomas;
- Camidge, D. Ross;
- Goldman, Jonathan W.;
- Sequist, Lecia V.;
- Piotrowska, Zofia;
- Wakelee, Heather A.;
- Neal, Joel W.
Publication type:
Article
Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study.
Published in:
Molecular Cancer, 2024, v. 23, p. 1, doi. 10.1186/s12943-024-02014-x
By:
- Xie, Mingchao;
- Vuko, Miljenka;
- Rodriguez-Canales, Jaime;
- Zimmermann, Johannes;
- Schick, Markus;
- O'Brien, Cathy;
- Paz-Ares, Luis;
- Goldman, Jonathan W.;
- Garassino, Marina Chiara;
- Gay, Carl M.;
- Heymach, John V.;
- Jiang, Haiyi;
- Barrett, J. Carl;
- Stewart, Ross A.;
- Lai, Zhongwu;
- Byers, Lauren A.;
- Rudin, Charles M.;
- Shrestha, Yashaswi
Publication type:
Article
Erratum to: Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
Published in:
2016
By:
- Bendell, Johanna;
- Rosen, Lee;
- Mayer, Robert;
- Goldman, Jonathan;
- Infante, Jeffrey;
- Benedetti, Fabio;
- Lin, Donghu;
- Mizuguchi, Hirokazu;
- Zergebel, Christopher;
- Patel, Manish;
- Bendell, Johanna C;
- Rosen, Lee S;
- Mayer, Robert J;
- Goldman, Jonathan W;
- Infante, Jeffrey R;
- Patel, Manish R
Publication type:
corrected article
Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
Published in:
2015
By:
- Bendell, Johanna;
- Rosen, Lee;
- Mayer, Robert;
- Goldman, Jonathan;
- Infante, Jeffrey;
- Benedetti, Fabio;
- Lin, Donghu;
- Mizuguchi, Hirokazu;
- Zergebel, Christopher;
- Patel, Manish;
- Bendell, Johanna C;
- Rosen, Lee S;
- Mayer, Robert J;
- Goldman, Jonathan W;
- Infante, Jeffrey R;
- Patel, Manish R
Publication type:
journal article
nab-Paclitaxel-Based Therapy in Underserved Patient Populations: The ABOUND.70+ Study in Elderly Patients With Advanced NSCLC.
Published in:
Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00262
By:
- Langer, Corey J.;
- Kim, Edward S.;
- Anderson, Eric C.;
- Jotte, Robert M.;
- Modiano, Manuel;
- Haggstrom, Daniel E.;
- Socoteanu, Matei P.;
- Smith, David A.;
- Dakhil, Christopher;
- Konduri, Kartik;
- Berry, Tymara;
- Ong, Teng J.;
- Sanford, Alexandra;
- Amiri, Katayoun;
- Goldman, Jonathan W.;
- Weiss, Jared;
- on behalf of the ABOUND.70+ Investigators;
- Gajra;
- Dobrescu;
- Halibey
Publication type:
Article
A first-in-human phase 1 study of a hepcidin monoclonal antibody, LY2787106, in cancer-associated anemia.
Published in:
Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-017-0427-x
By:
- Vadhan-Raj, Saroj;
- Abonour, Rafat;
- Goldman, Jonathan W.;
- Smith, David A.;
- Slapak, Christopher A.;
- Ilaria Jr., Robert L.;
- Tiu, Ramon V.;
- Xuejing Wang;
- Callies, Sophie;
- Joanne Cox;
- Tuttle, Jay L.;
- Yiu-Keung Lau;
- Roeland, Eric J.
Publication type:
Article
Effects of Rovalpituzumab Tesirine on Ventricular Repolarization in Patients With Small‐Cell Lung Cancer.
Published in:
CTS: Clinical & Translational Science, 2021, v. 14, n. 2, p. 664, doi. 10.1111/cts.12928
By:
- Goldman, Jonathan W.;
- Barve, Minal;
- Patel, Jyoti D.;
- Wozniak, Antoinette;
- Dowlati, Afshin;
- Starodub, Alexander;
- Owonikoko, Taofeek K.;
- Edenfield, William;
- Laurie, Scott A.;
- Da Costa, Daniel;
- Lally, Satwant;
- Koch, Martina;
- Kosloski, Matthew P.;
- Hoffman, David;
- Dy, Grace K.
Publication type:
Article
Summary of Research: Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC.
Published in:
2024
By:
- Tsuboi, Masahiro;
- Herbst, Roy S.;
- John, Thomas;
- Kato, Terufumi;
- Majem, Margarita;
- Grohé, Christian;
- Wang, Jie;
- Goldman, Jonathan W.;
- Lu, Shun;
- de Marinis, Filippo;
- Shepherd, Frances A.;
- Lee, Ki Hyeong;
- Le, Nhieu Thi;
- Dechaphunkul, Arunee;
- Kowalski, Dariusz;
- Bonanno, Laura;
- Dómine, Manuel;
- Poole, Lynne;
- Bolanos, Ana;
- Rukazenkov, Yuri
Publication type:
Letter
Non-small cell lung cancer clinical trials requiring biopsies with biomarker-specific results for enrollment provide unique challenges.
Published in:
2017
By:
- Spiegel, Marshall L.;
- Goldman, Jonathan W.;
- Wolf, Brian R.;
- Nameth, Danielle J.;
- Grogan, Tristan R.;
- Lisberg, Aaron E.;
- Wong, Deborah J. L.;
- Ledezma, Blanca A.;
- Mendenhall, Melody A.;
- Genshaft, Scott J.;
- Gutierrez, Antonio J.;
- Abtin, Fereidoun;
- Wallace, W.Dean;
- Adame, Carlos R.;
- McKenzie, Jordan R.;
- Abarca, Phillip A.;
- Li, Alice J.;
- Strunck, Jennifer L.;
- Famenini, Sina;
- Carroll, James M.
Publication type:
journal article
Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib.
Published in:
Cancer (0008543X), 2012, v. 118, n. 23, p. 5903, doi. 10.1002/cncr.27575
By:
- Goldman, Jonathan W.;
- Laux, Isett;
- Chai, Feng;
- Savage, Ronald E.;
- Ferrari, Dora;
- Garmey, Edward G.;
- Just, Richard G.;
- Rosen, Lee S.
Publication type:
Article
PD 1 checkpoint inhibition in solid organ transplants: 2 sides of a coin - case report.
Published in:
2018
By:
- Goldman, Jonathan W.;
- Abdalla, Basmah;
- Mendenhall, Melody A.;
- Sisk, Anthony;
- Hunt, Jaime;
- Danovitch, Gabriel M.;
- Lum, Erik L.
Publication type:
journal article
Hyperglycemia Associated With Targeted Oncologic Treatment: Mechanisms and Management.
Published in:
Oncologist, 2016, v. 21, n. 11, p. 1326, doi. 10.1634/theoncologist.2015-0519
By:
- Goldman, Jonathan W.;
- Mendenhall, Melody A.;
- Rettinger, Sarah R.
Publication type:
Article
A Randomized Phase III Study of Abemaciclib Versus Erlotinib in Patients with Stage IV Non-small Cell Lung Cancer With a Detectable KRAS Mutation Who Failed Prior Platinum-Based Therapy: JUNIPER.
Published in:
Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.578756
By:
- Goldman, Jonathan W.;
- Mazieres, Julien;
- Barlesi, Fabrice;
- Dragnev, Konstantin H.;
- Koczywas, Marianna;
- Göskel, Tuncay;
- Cortot, Alexis B.;
- Girard, Nicolas;
- Wesseler, Claas;
- Bischoff, Helge;
- Nadal, Ernest;
- Park, Keunchil;
- Lu, Shun;
- Taus, Alvaro;
- Cobo, Manuel;
- Estrem, Shawn T.;
- Wijayawardana, Sameera R.;
- Turner, Kellie;
- Oakley III, Gerard Joseph;
- Hurt, Karla C.
Publication type:
Article
Safety and Efficacy Results of a Phase I, Open-Label Study of Concurrent and Delayed Nivolumab in Combination With nab -Paclitaxel and Carboplatin in Advanced Non-small Cell Lung Cancer.
Published in:
Frontiers in Oncology, 2019, v. 9, p. 1, doi. 10.3389/fonc.2019.01256
By:
- Goldman, Jonathan W.;
- Waterhouse, David M.;
- George, Ben;
- O'Dwyer, Peter J.;
- Bhore, Rafia;
- Banerjee, Sibabrata;
- Lyons, Larry;
- Louis, Chrystal U.;
- Ong, Teng Jin;
- Kelly, Karen
Publication type:
Article
A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.
Published in:
BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-152
By:
- Goldman, Jonathan W.;
- Raju, Robert N.;
- Gordon, Gregory A.;
- El-Hariry, Iman;
- Teofilivici, Florentina;
- Vukovic, Vojo M.;
- Bradley, Robert;
- Karol, Michael D.;
- Yu Chen;
- Wei Guo;
- Inoue, Takayo;
- Rosen, Lee S
Publication type:
Article
A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.
Published in:
2013
By:
- Goldman, Jonathan W;
- Raju, Robert N;
- Gordon, Gregory A;
- El-Hariry, Iman;
- Teofilivici, Florentina;
- Vukovic, Vojo M;
- Bradley, Robert;
- Karol, Michael D;
- Chen, Yu;
- Guo, Wei;
- Inoue, Takayo;
- Rosen, Lee S
Publication type:
journal article

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