Found: 29
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Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34493-1
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- Article
Disease modeling by efficient genome editing using a near PAM-less base editor in vivo.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31172-z
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- Article
Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells.
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- PLoS Genetics, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pgen.1008355
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- Article
The human DNA ends proteome uncovers an unexpected entanglement of functional pathways.
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- Nucleic Acids Research, 2016, v. 44, n. 10, p. 4721, doi. 10.1093/nar/gkw121
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- Article
Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates.
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- Nucleic Acids Research, 2008, v. 36, n. 11, p. 3531, doi. 10.1093/nar/gkn231
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- Article
Cellular antisense activity of peptide nucleic acid (PNAs) targeted to HIV-1 polypurine tract (PPT) containing RNA.
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- Nucleic Acids Research, 2007, v. 35, n. 12, p. 3907, doi. 10.1093/nar/gkm374
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- Article
A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.
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- Nucleic Acids Research, 2007, v. 35, n. 9, p. e65, doi. 10.1093/nar/gkm152
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- Article
Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: study of efficiency dependence on DNA nuclear environment.
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- Nucleic Acids Research, 2006, v. 34, n. 16, p. 4546, doi. 10.1093/nar/gkl630
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- Article
Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo.
- Published in:
- Nature Biotechnology, 2001, v. 19, n. 1, p. 40, doi. 10.1038/83489
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- Article
Triplex technology takes off.
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- Nature Biotechnology, 2000, v. 18, n. 12, p. 1245, doi. 10.1038/82348
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- Article
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 500, doi. 10.1038/nsmb.2029
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- Article
Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
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- Scientific Reports, 2015, p. 1, doi. 10.1038/srep14410
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- Article
The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination.
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- Multiple Sclerosis Journal, 2018, v. 24, n. 11, p. 1421, doi. 10.1177/1352458517721355
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- Article
Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110371
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- Article
De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.
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- Molecular Cancer, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12943-022-01520-0
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- Article
Flavin Conjugates for Delivery of Peptide Nucleic Acids.
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- ChemBioChem, 2012, v. 13, n. 17, p. 2593, doi. 10.1002/cbic.201200505
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- Article
Delivery of Oligonucleotides and Analogues: The Oligonucleotide Conjugate-Based Approach.
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- ChemBioChem, 2010, v. 11, n. 11, p. 1493, doi. 10.1002/cbic.201000138
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- Article
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides.
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- Nucleic Acids Research, 2006, v. 34, n. 6, p. 1900, doi. 10.1093/nar/gkl126
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- Article
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.
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- Nucleic Acids Research, 2005, v. 33, n. 13, p. 4223, doi. 10.1093/nar/gki726
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- Article
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs.
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- Nucleic Acids Research, 2005, v. 33, n. 12, p. 3733, doi. 10.1093/nar/gki686
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- Article
Covalent crosslinks introduced via a triple helix‐forming oligonucleotide coupled to psoralen are inefficiently repaired.
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- Nucleic Acids Research, 1999, v. 27, n. 3, p. 743, doi. 10.1093/nar/27.3.743
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- Article
Triple Helix-Mediated Inhibition of Gene Expression Is Increased by PUVA.
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- Journal of Investigative Dermatology, 2004, v. 122, n. 5, p. 1114, doi. 10.1111/j.0022-202X.2004.22521.x
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- Article
Claude Hélène (1938-2003): Nucleinsäuren in Biologie und Chemie.
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- Angewandte Chemie, 2003, v. 115, n. 18, p. 2042, doi. 10.1002/ange.200390417
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- Article
Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels.
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- Journal of Gene Medicine, 2005, v. 7, n. 2, p. 198, doi. 10.1002/jgm.659
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- Article
Triplex-forming molecules: from concepts to applications.
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- Journal of Gene Medicine, 2001, v. 3, n. 4, p. 299, doi. 10.1002/jgm.192
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- Article
Claude Hélène (19382003): Nucleic Acids in Biology and Chemistry.
- Published in:
- Angewandte Chemie International Edition, 2003, v. 42, n. 18, p. 1996, doi. 10.1002/anie.200390442
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Book Review: Antisense Drug Technology Edited by Stanley T. Crooke.
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- Angewandte Chemie International Edition, 2003, v. 42, n. 10, p. 1083, doi. 10.1002/anie.200390311
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- Article
High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30188-0
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- Article
Therapeutic Oligonucleotides. Edited by Jens Kurreck.
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- ChemBioChem, 2008, v. 9, n. 18, p. 3087, doi. 10.1002/cbic.200800738
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- Article