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Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 3, p. 1, doi. 10.15252/emmm.202216104
By:
- Brundu, Serena;
- Napolitano, Virginia;
- Franzolin, Giulia;
- Lo Cascio, Ettore;
- Mastrantonio, Roberta;
- Sardo, Gabriele;
- Cascardi, Eliano;
- Verginelli, Federica;
- Sarnataro, Sergio;
- Gambardella, Gennaro;
- Pisacane, Alberto;
- Arcovito, Alessandro;
- Boccaccio, Carla;
- Comoglio, Paolo M;
- Giraudo, Enrico;
- Tamagnone, Luca
Publication type:
Article
Cancer of Unknown Primary (CUP): genetic evidence for a novel nosological entity? A case report.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 7, p. 1, doi. 10.15252/emmm.201911756
By:
- Benvenuti, Silvia;
- Milan, Melissa;
- Geuna, Elena;
- Pisacane, Alberto;
- Senetta, Rebecca;
- Gambardella, Gennaro;
- Stella, Giulia M;
- Montemurro, Filippo;
- Sapino, Anna;
- Boccaccio, Carla;
- Comoglio, Paolo M
Publication type:
Article
Single-cell gene set enrichment analysis and transfer learning for functional annotation of scRNA-seq data.
Published in:
NAR Genomics & Bioinformatics, 2023, v. 5, n. 1, p. 1, doi. 10.1093/nargab/lqad024
By:
- Franchini, Melania;
- Pellecchia, Simona;
- Viscido, Gaetano;
- Gambardella, Gennaro
Publication type:
Article
Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.
Published in:
Nucleic Acids Research, 2013, v. 41, n. 2, p. 711, doi. 10.1093/nar/gks1136
By:
- De Cegli, Rossella;
- Iacobacci, Simona;
- Flore, Gemma;
- Gambardella, Gennaro;
- Mao, Lei;
- Cutillo, Luisa;
- Lauria, Mario;
- Klose, Joachim;
- Illingworth, Elizabeth;
- Banfi, Sandro;
- di Bernardo, Diego
Publication type:
Article
Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22643-w
By:
- Verginelli, Federica;
- Pisacane, Alberto;
- Gambardella, Gennaro;
- D'Ambrosio, Antonio;
- Candiello, Ermes;
- Ferrio, Marco;
- Panero, Mara;
- Casorzo, Laura;
- Benvenuti, Silvia;
- Cascardi, Eliano;
- Senetta, Rebecca;
- Geuna, Elena;
- Ballabio, Andrea;
- Montemurro, Filippo;
- Sapino, Anna;
- Comoglio, Paolo M.;
- Boccaccio, Carla
Publication type:
Article
Single cell lineage tracing reveals clonal dynamics of anti-EGFR therapy resistance in triple negative breast cancer.
Published in:
Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01327-2
By:
- Pellecchia, Simona;
- Franchini, Melania;
- Viscido, Gaetano;
- Arnese, Riccardo;
- Gambardella, Gennaro
Publication type:
Article
MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT axis.
Published in:
Molecular Oncology, 2023, v. 17, n. 7, p. 1280, doi. 10.1002/1878-0261.13408
By:
- Candiello, Ermes;
- Reato, Gigliola;
- Verginelli, Federica;
- Gambardella, Gennaro;
- D′Ambrosio, Antonio;
- Calandra, Noemi;
- Orzan, Francesca;
- Iuliano, Antonella;
- Albano, Raffaella;
- Sassi, Francesco;
- Luraghi, Paolo;
- Comoglio, Paolo M.;
- Bertotti, Andrea;
- Trusolino, Livio;
- Boccaccio, Carla
Publication type:
Article
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data.
Published in:
BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0700-3
By:
- Gambardella, Gennaro;
- Peluso, Ivana;
- Montefusco, Sandro;
- Bansal, Mukesh;
- Medina, Diego L.;
- Lawrence, Neil;
- di Bernardo, Diego
Publication type:
Article
A reverse-engineering approach to dissect post-translational modulators of transcription factor’s activity from transcriptional data.
Published in:
BMC Bioinformatics, 2015, v. 16, n. 1, p. 279, doi. 10.1186/s12859-015-0700-3
By:
- Gambardella, Gennaro;
- Peluso, Ivana;
- Montefusco, Sandro;
- Bansal, Mukesh;
- Medina, Diego L.;
- Lawrence, Neil;
- di Bernardo, Diego
Publication type:
Article
The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 14126, doi. 10.1038/ncomms14126
By:
- Gambardella, Gennaro;
- Carissimo, Annamaria;
- Chen, Amy;
- Cutillo, Luisa;
- Nowakowski, Tomasz J.;
- di Bernardo, Diego;
- Blelloch, Robert
Publication type:
Article
Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes.
Published in:
Nature Communications, 2016, v. 7, n. 7, p. 12072, doi. 10.1038/ncomms12072
By:
- Cereda, Matteo;
- Gambardella, Gennaro;
- Benedetti, Lorena;
- Iannelli, Fabio;
- Patel, Dominic;
- Basso, Gianluca;
- Guerra, Rosalinda F.;
- Mourikis, Thanos P.;
- Puccio, Ignazio;
- Sinha, Shruti;
- Laghi, Luigi;
- Spencer, Jo;
- Rodriguez-Justo, Manuel;
- Ciccarelli, Francesca D.
Publication type:
Article
Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.
Published in:
Nature Communications, 2014, v. 5, n. 9, p. 4830, doi. 10.1038/ncomms5830
By:
- Racioppi, Claudia;
- Kamal, Ashwani K.;
- Razy-Krajka, Florian;
- Gambardella, Gennaro;
- Zanetti, Laura;
- di Bernardo, Diego;
- Sanges, Remo;
- Christiaen, Lionel A.;
- Ristoratore, Filomena
Publication type:
Article
TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels.
Published in:
Journal of Physiology, 2019, v. 597, n. 24, p. 5859, doi. 10.1113/JP278784
By:
- Genovese, Michele;
- Borrelli, Anna;
- Venturini, Arianna;
- Guidone, Daniela;
- Caci, Emanuela;
- Viscido, Gaetano;
- Gambardella, Gennaro;
- di Bernardo, Diego;
- Scudieri, Paolo;
- Galietta, Luis J.V.
Publication type:
Article
O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR.
Published in:
Glycobiology, 2021, v. 31, n. 3, p. 200, doi. 10.1093/glycob/cwaa075
By:
- Tajadura-Ortega, Virginia;
- Gambardella, Gennaro;
- Skinner, Alexandra;
- Halim, Adnan;
- Coillie, Julie Van;
- Schjoldager, Katrine Ter-Borch Gram;
- Beatson, Richard;
- Graham, Rosalind;
- Achkova, Daniela;
- Taylor-Papadimitriou, Joyce;
- Ciccarelli, Francesca D;
- Burchell, Joy M
Publication type:
Article
MEGA-V: detection of variant gene sets in patient cohorts.
Published in:
Bioinformatics, 2017, v. 33, n. 8, p. 1248, doi. 10.1093/bioinformatics/btw809
By:
- Gambardella, Gennaro;
- Cereda, Matteo;
- Benedetti, Lorena;
- Ciccarelli, Francesca D.
Publication type:
Article
Differential network analysis for the identification of condition-specific pathway activity and regulation.
Published in:
Bioinformatics, 2013, v. 29, n. 14, p. 1776, doi. 10.1093/bioinformatics/btt290
By:
- Gambardella, Gennaro;
- Moretti, Maria Nicoletta;
- de Cegli, Rossella;
- Cardone, Luca;
- Peron, Adriano;
- di Bernardo, Diego
Publication type:
Article
Correction: Predicting drug response from single-cell expression profiles of tumours.
Published in:
BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03289-z
By:
- Pellecchia, Simona;
- Viscido, Gaetano;
- Franchini, Melania;
- Gambardella, Gennaro
Publication type:
Article
Predicting drug response from single-cell expression profiles of tumours.
Published in:
BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03182-1
By:
- Pellecchia, Simona;
- Viscido, Gaetano;
- Franchini, Melania;
- Gambardella, Gennaro
Publication type:
Article

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