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Glycyrrhetinic acid induces G1.phase cell cycle arrest in human non.small cell lung cancer cells through endoplasmic reticulum stress pathway.
- Published in:
- International Journal of Oncology, 2015, v. 46, n. 3, p. 981, doi. 10.3892/ijo.2015.2819
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- Publication type:
- Article
Akt phosphorylates acinus and inhibits its proteolytic cleavage, preventing chromatin condensation.
- Published in:
- EMBO Journal, 2005, v. 24, n. 20, p. 3543, doi. 10.1038/sj.emboj.7600823
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- Publication type:
- Article
Experimental Validation of Bioinformatically Prioritized Therapeutic Hypotheses and Targets for Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.078862
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- Publication type:
- Article
The Emory‐Sage‐SGC TREAT‐AD Center: Tool development for novel targets in Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076912
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- Publication type:
- Article
Efforts toward discovering inhibitors of the SYK SH2–FCER1γ interaction as potential Alzheimer's disease chemical probes and therapeutics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076479
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- Publication type:
- Article
Towards the development of a chemical probe targeting the disruption of SYK tandem SH2 domain and FCεR1γ interactions for Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067392
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- Publication type:
- Article
The Emory‐Sage‐SGC TREAT‐AD Center: Tool and probe development for emerging targets in Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.064748
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- Publication type:
- Article
Tool and chemical probe development for emerging targets in Alzheimer's disease: The Emory‐Sage‐SGC TREAT‐AD Center.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051447
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- Publication type:
- Article
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
- Published in:
- PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0293548
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- Publication type:
- Article
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 9, p. 2133, doi. 10.1007/s11095-023-03596-9
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- Article
Dual gene activation and knockout screen reveals directional dependencies in genetic networks.
- Published in:
- Nature Biotechnology, 2018, v. 36, n. 2, p. 170, doi. 10.1038/nbt.4062
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- Publication type:
- Article
14-3-3 adaptor proteins recruit AID to 5?-AGCT-3?–rich switch regions for class switch recombination.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1124, doi. 10.1038/nsmb.1884
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- Publication type:
- Article
Raf-1 activation disrupts its binding to keratins during cell stress.
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- Journal of Cell Biology, 2004, v. 166, n. 4, p. 479, doi. 10.1083/jcb.200402051
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- Publication type:
- Article
Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice.
- Published in:
- Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-023-38010-w
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- Publication type:
- Article
Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells.
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- Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-01984-1
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- Publication type:
- Article
A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the SMAD4–SMAD3–DNA complex.
- Published in:
- Journal of Molecular Cell Biology, 2023, v. 15, n. 11, p. 1, doi. 10.1093/jmcb/mjad068
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- Publication type:
- Article
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
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- Journal of Molecular Cell Biology, 2023, v. 15, n. 3, p. 1, doi. 10.1093/jmcb/mjad017
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- Publication type:
- Article
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening.
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- Journal of Molecular Cell Biology, 2020, v. 12, n. 8, p. 630, doi. 10.1093/jmcb/mjaa036
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- Publication type:
- Article
NSD3S stabilizes MYC through hindering its interaction with FBXW7.
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- Journal of Molecular Cell Biology, 2020, v. 12, n. 6, p. 438, doi. 10.1093/jmcb/mjz098
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- Publication type:
- Article
Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1.
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- Journal of Molecular Cell Biology, 2018, v. 10, n. 6, p. 549, doi. 10.1093/jmcb/mjy061
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- Publication type:
- Article
Enabling systematic interrogation of protein--protein interactions in live cells with a versatile ultra-high-throughput biosensor platform.
- Published in:
- Journal of Molecular Cell Biology, 2016, v. 8, n. 3, p. 271, doi. 10.1093/jmcb/mjv064
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- Publication type:
- Article
Autophagy and Apoptosis in Hepatocellular Carcinoma Induced by EF25-(GSH)<sub>2</sub>: A Novel Curcumin Analog.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107876
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- Publication type:
- Article
Transcriptional Regulation of <i>YWHAZ</i>, the Gene Encoding 14-3-3ζ.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093480
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- Publication type:
- Article
Identification of FAKTS as a novel 14-3-3-associated nuclear protein.
- Published in:
- Proteins, 2007, v. 67, n. 2, p. 479, doi. 10.1002/prot.21288
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- Publication type:
- Article
Role of the 14-3-3 C-terminal loop in ligand interaction.
- Published in:
- Proteins, 2002, v. 49, n. 3, p. 321, doi. 10.1002/prot.10210
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- Publication type:
- Article
Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts.
- Published in:
- Evidence-based Complementary & Alternative Medicine (eCAM), 2013, v. 2013, p. 1, doi. 10.1155/2013/160168
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- Publication type:
- Article
Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 937, doi. 10.3390/biom13060937
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- Article
A NaCl-regulated plant gene encoding a brain protein homolog that activates ADP ribosyltransferase and inhibits protein kinase C.
- Published in:
- Plant Journal, 1994, v. 6, n. 5, p. 729, doi. 10.1046/j.1365-313X.1994.6050729.x
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- Publication type:
- Article
Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.
- Published in:
- Oncogene, 2004, v. 23, n. 29, p. 5099, doi. 10.1038/sj.onc.1207668
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- Article
Acetylation regulates ribonucleotide reductase activity and cancer cell growth.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-11214-9
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- Publication type:
- Article
Photic Regulation of Arylalkylamine N-Acetyltransferase Binding to 14-3-3 Proteins in Retinal Photoreceptor Cells.
- Published in:
- Journal of Neuroscience, 2006, v. 26, n. 36, p. 9153, doi. 10.1523/JNEUROSCI.1384-06.2006
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- Publication type:
- Article
A Novel Herbal Formula Induces Cell Cycle Arrest and Apoptosis in Association With Suppressing the PI3K/AKT Pathway in Human Lung Cancer A549 Cells.
- Published in:
- Integrative Cancer Therapies, 2014, v. 13, n. 2, p. 152, doi. 10.1177/1534735413503544
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- Publication type:
- Article
THER-17. BRAF-V600E DEGRADATION AS A THERAPEUTIC STRATEGY IN BRAF-V600E MUTANT GLIOMAS.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii117, doi. 10.1093/neuonc/noz036.224
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- Publication type:
- Article
Mechanisms of SPOP mutant‐mediated oncogenesis.
- Published in:
- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04551
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- Article
Identification of higenamine as a novel α<sub>1</sub> -adrenergic receptor antagonist.
- Published in:
- 2019
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- Publication type:
- journal article
Modulation of 14-3-3 Protein Interactions with Target Polypeptides by Physical and Metabolic Effectors.
- Published in:
- Plant & Cell Physiology, 2000, v. 41, n. 4, p. 523, doi. 10.1093/pcp/41.4.523
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- Publication type:
- Article
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
- Published in:
- Nature Communications, 2017, v. 8, n. 3, p. 14740, doi. 10.1038/ncomms14740
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- Publication type:
- Article
cAMP/adenylyl cyclase stimulation promotes 14-3-3 binding to UT-A1 urea transporter.
- Published in:
- FASEB Journal, 2007, v. 21, n. 6, p. A906
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- Publication type:
- Article
High expression of MKK3 is associated with worse clinical outcomes in African American breast cancer patients.
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- 2020
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- Publication type:
- journal article
Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction.
- Published in:
- Assay & Drug Development Technologies, 2018, v. 16, n. 2, p. 96, doi. 10.1089/adt.2017.835
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- Publication type:
- Article
Screening and Functional Profiling of Small-Molecule HIV-1 Entry and Fusion Inhibitors.
- Published in:
- Assay & Drug Development Technologies, 2017, v. 15, n. 2, p. 53, doi. 10.1089/adt.2017.777
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- Publication type:
- Article
High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors.
- Published in:
- Assay & Drug Development Technologies, 2015, v. 13, n. 3, p. 155, doi. 10.1089/adt.2015.639
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- Publication type:
- Article
A Time-Resolved Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of 14-3-3 Protein-Protein Interaction Inhibitors.
- Published in:
- Assay & Drug Development Technologies, 2013, v. 11, n. 6, p. 367, doi. 10.1089/adt.2013.507
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- Publication type:
- Article
A Dual-Readout F2Assay That Combines Fluorescence Resonance Energy Transfer and Fluorescence Polarization for Monitoring Bimolecular Interactions.
- Published in:
- Assay & Drug Development Technologies, 2011, v. 9, n. 4, p. 382, doi. 10.1089/adt.2010.0292
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- Publication type:
- Article
Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells.
- Published in:
- International Journal of Oncology, 2016, v. 49, n. 1, p. 316, doi. 10.3892/ijo.2016.3514
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- Publication type:
- Article
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κ B pathway.
- Published in:
- International Journal of Cancer, 2015, v. 136, n. 10, p. 2341, doi. 10.1002/ijc.29301
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- Publication type:
- Article
BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 5, p. 1, doi. 10.1038/s41419-018-0500-6
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- Publication type:
- Article
MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.
- Published in:
- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170339
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- Publication type:
- Article
2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells.
- Published in:
- PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168793
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- Publication type:
- Article
Polyethylene-glycol-coated gold nanoparticles improve cardiac function after myocardial infarction in mice.
- Published in:
- Canadian Journal of Physiology & Pharmacology, 2018, v. 96, n. 12, p. 1318, doi. 10.1139/cjpp-2018-0227
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- Publication type:
- Article