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Area under the curve achievement of once daily tobramycin in children with cystic fibrosis during clinical care.
Published in:
Pediatric Pulmonology, 2020, v. 55, n. 12, p. 3343, doi. 10.1002/ppul.25037
By:
- Brockmeyer, Jake M.;
- Wise, Russell T.;
- Burgener, Elizabeth B.;
- Milla, Carlos;
- Frymoyer, Adam
Publication type:
Article
Predictive Performance of a Vancomycin Population Pharmacokinetic Model in Neonates.
Published in:
Infectious Diseases & Therapy, 2015, v. 4, n. 2, p. 187, doi. 10.1007/s40121-015-0067-9
By:
- Stockmann, Chris;
- Hersh, Adam;
- Roberts, Jessica;
- Bhongsatiern, Jiraganya;
- Korgenski, Ernest;
- Spigarelli, Michael;
- Sherwin, Catherine;
- Frymoyer, Adam
Publication type:
Article
Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach.
Published in:
Journal of the Pediatric Infectious Diseases Society, 2019, v. 8, n. 2, p. 97, doi. 10.1093/jpids/pix109
By:
- Frymoyer, Adam;
- Stockmann, Chris;
- Hersh, Adam L;
- Goswami, Srijib;
- Keizer, Ron J
Publication type:
Article
Vancomycin Dosing Practices, Trough Concentrations, and Predicted Area Under the Curve in Children With Suspected Invasive Staphylococcal Infections.
Published in:
2013
By:
- Frymoyer, Adam
Publication type:
Letter
Rescaling Creatinine Centiles in Neonates Treated with Therapeutic Hypothermia for Neonatal Encephalopathy.
Published in:
Neonatology (16617800), 2022, v. 119, n. 6, p. 792, doi. 10.1159/000526738
By:
- Allegaert, Karel;
- Mekahli, Djalila;
- Wintermark, Pia;
- Groenendaal, Floris;
- Borloo, Noor;
- Laenen, Annouschka;
- Annaert, Pieter;
- Şahin, Suzan;
- Öncel, Mehmet Yekta;
- Chock, Valerie Y.;
- Armangil, Didem;
- Koc, Esin;
- Battin, Malcolm R.;
- Frymoyer, Adam;
- Keles, Elif;
- Smits, Anne
Publication type:
Article
Serum Creatinine Patterns in Neonates Treated with Therapeutic Hypothermia for Neonatal Encephalopathy.
Published in:
Neonatology (16617800), 2022, v. 119, n. 6, p. 686, doi. 10.1159/000525574
By:
- Keles, Elif;
- Wintermark, Pia;
- Groenendaal, Floris;
- Borloo, Noor;
- Smits, Anne;
- Laenen, Annouschka;
- Mekahli, Djalila;
- Annaert, Pieter;
- Şahin, Suzan;
- Öncel, Mehmet Yekta;
- Chock, Valerie;
- Armangil, Didem;
- Koc, Esin;
- Battin, Malcolm R.;
- Frymoyer, Adam;
- Allegaert, Karel
Publication type:
Article
Resource Utilization and Costs Associated with Approaches to Identify Infants with Early-Onset Sepsis.
Published in:
MDM Policy & Practice, 2024, v. 9, n. 1, p. 1, doi. 10.1177/23814683231226129
By:
- Guan, Grace;
- Joshi, Neha S.;
- Frymoyer, Adam;
- Achepohl, Grace D.;
- Dang, Rebecca;
- Taylor, N. Kenji;
- Salomon, Joshua A.;
- Goldhaber-Fiebert, Jeremy D.;
- Owens, Douglas K.
Publication type:
Article
Population pharmacokinetics of etomidate in neonates and infants with congenital heart disease.
Published in:
Biopharmaceutics & Drug Disposition, 2015, v. 36, n. 2, p. 104, doi. 10.1002/bdd.1924
By:
- Su, Felice;
- El‐Komy, Mohammed H.;
- Hammer, Gregory B.;
- Frymoyer, Adam;
- Cohane, Carol A.;
- Drover, David R.
Publication type:
Article
A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia.
Published in:
AAPS Journal, 2024, v. 26, n. 1, p. 1, doi. 10.1208/s12248-023-00851-0
By:
- Krzyzanski, Wojciech;
- Wintermark, Pia;
- Annaert, Pieter;
- Groenendaal, Floris;
- Şahin, Suzan;
- Öncel, Mehmet Yekta;
- Armangil, Didem;
- Koc, Esin;
- Battin, Malcolm R.;
- Gunn, Alistair J.;
- Frymoyer, Adam;
- Chock, Valerie Y.-L.;
- Keles, Elif;
- Mekahli, Djalila;
- van den Anker, John;
- Smits, Anne;
- Allegaert, Karel
Publication type:
Article
Pharmacokinetics of Morphine and Its Metabolites in Infants and Young Children After Congenital Heart Surgery.
Published in:
AAPS Journal, 2016, v. 18, n. 1, p. 124, doi. 10.1208/s12248-015-9826-5
By:
- Elkomy, Mohammed;
- Drover, David;
- Glotzbach, Kristi;
- Galinkin, Jeffery;
- Frymoyer, Adam;
- Su, Felice;
- Hammer, Gregory
Publication type:
Article
The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1358, doi. 10.1208/s12248-014-9673-9
By:
- Yago, Marc;
- Frymoyer, Adam;
- Benet, Leslie;
- Smelick, Gillian;
- Frassetto, Lynda;
- Ding, Xiao;
- Dean, Brian;
- Salphati, Laurent;
- Budha, Nageshwar;
- Jin, Jin;
- Dresser, Mark;
- Ware, Joseph
Publication type:
Article
Letter to the Editor regarding "Arrhythmias in the paediatric ICU: a prospective study of the rates and predictors of arrhythmias in children without underlying cardiac disease" by Cassel-Choudhury et al.
Published in:
2017
By:
- Axelrod, David M.;
- Frymoyer, Adam R.;
- Sutherland, Scott M.
Publication type:
Letter
Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children's Hospital.
Published in:
Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00551
By:
- Frymoyer, Adam;
- Schwenk, Hayden T.;
- Zorn, Yvonne;
- Bio, Laura;
- Moss, Jeffrey D.;
- Chasmawala, Bhavin;
- Faulkenberry, Joshua;
- Goswami, Srijib;
- Keizer, Ron J.;
- Ghaskari, Shabnam
Publication type:
Article
A population physiologically‐based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 290, doi. 10.1111/bcp.14963
By:
- Chang, Hsuan Ping;
- Shakhnovich, Valentina;
- Frymoyer, Adam;
- Funk, Ryan Sol;
- Becker, Mara L.;
- Park, K. T.;
- Shah, Dhaval K.
Publication type:
Article
Population pharmacokinetics of unbound mycophenolic acid in adult allogeneic haematopoietic cell transplantation: effect of pharmacogenetic factors.
Published in:
British Journal of Clinical Pharmacology, 2013, v. 75, n. 2, p. 463, doi. 10.1111/j.1365-2125.2012.04372.x
By:
- Frymoyer, Adam;
- Verotta, Davide;
- Jacobson, Pamala;
- Long‐Boyle, Janel
Publication type:
Article
Acute kidney injury in neonates with hypoxic ischemic encephalopathy based on serum creatinine decline compared to KDIGO criteria.
Published in:
Pediatric Nephrology, 2024, v. 39, n. 9, p. 2789, doi. 10.1007/s00467-024-06287-8
By:
- Ahn, Haejun C.;
- Frymoyer, Adam;
- Boothroyd, Derek B.;
- Bonifacio, Sonia;
- Sutherland, Scott M.;
- Chock, Valerie Y.
Publication type:
Article
Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia.
Published in:
Pediatric Nephrology, 2023, v. 38, n. 8, p. 2839, doi. 10.1007/s00467-023-05892-3
By:
- Rumpel, Jennifer A.;
- Spray, Beverly J.;
- Frymoyer, Adam;
- Rogers, Sydney;
- Cho, Seo-Ho;
- Ranabothu, Saritha;
- Blaszak, Richard;
- Courtney, Sherry E.;
- Chock, Valerie Y.
Publication type:
Article
Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit?
Published in:
Cancers, 2020, v. 12, n. 2, p. 441, doi. 10.3390/cancers12020441
By:
- Wojcicki, Anna V.;
- Kadapakkam, Meena;
- Frymoyer, Adam;
- Lacayo, Norman;
- Chae, Hee-Don;
- Sakamoto, Kathleen M.
Publication type:
Article
Incidence of Neonatal Hypothermia in the Newborn Nursery and Associated Factors.
Published in:
JAMA Network Open, 2023, v. 6, n. 8, p. e2331011, doi. 10.1001/jamanetworkopen.2023.31011
By:
- Dang, Rebecca;
- Patel, Anisha I.;
- Weng, Yingjie;
- Schroeder, Alan R.;
- Lee, Henry C.;
- Aby, Janelle;
- Frymoyer, Adam
Publication type:
Article
A safety, tolerability, and pharmacokinetic analysis of two phase I studies of multitargeted small molecule tyrosine kinase inhibitor XL647 with an intermittent and continuous dosing schedule in patients with advanced solid malignancies.
Published in:
2018
By:
- Padda, Sukhmani K.;
- Sikic, Branimir I.;
- Wakelee, Heather A.;
- Das, Millie;
- Frymoyer, Adam;
- Molina, Julian;
- Adjei, Alex;
- Lensing, Janet L.;
- Miles, Dale
Publication type:
journal article
Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 12, p. 785, doi. 10.1002/psp4.12353
By:
- Keizer, Ron J.;
- ter Heine, Rob;
- Frymoyer, Adam;
- Lesko, Lawrence J.;
- Mangat, Ranvir;
- Goswami, Srijib
Publication type:
Article
Decreased Morphine Clearance in Neonates With Hypoxic Ischemic Encephalopathy Receiving Hypothermia.
Published in:
Journal of Clinical Pharmacology, 2017, v. 57, n. 1, p. 64, doi. 10.1002/jcph.775
By:
- Frymoyer, Adam;
- Bonifacio, Sonia L.;
- Drover, David R.;
- Su, Felice;
- Wustoff, Courtney J.;
- Meurs, Krisa P.
Publication type:
Article
Theophylline Population Pharmacokinetics and Dosing in Children Following Congenital Heart Surgery With Cardiopulmonary Bypass.
Published in:
Journal of Clinical Pharmacology, 2016, v. 56, n. 9, p. 1084, doi. 10.1002/jcph.697
By:
- Frymoyer, Adam;
- Su, Felice;
- Grimm, Paul C.;
- Sutherland, Scott M.;
- Axelrod, David M.
Publication type:
Article
Impact of model‐informed precision dosing on achievement of vancomycin exposure targets in pediatric patients with cystic fibrosis.
Published in:
Pharmacotherapy, 2023, v. 43, n. 10, p. 1007, doi. 10.1002/phar.2845
By:
- Frymoyer, Adam;
- Schwenk, Hayden T.;
- Brockmeyer, Jake M.;
- Bio, Laura
Publication type:
Article
Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia.
Published in:
Pharmacotherapy, 2013, v. 33, n. 7, p. 718, doi. 10.1002/phar.1263
By:
- Frymoyer, Adam;
- Meng, Lina;
- Bonifacio, Sonia L.;
- Verotta, Davide;
- Guglielmo, B. Joseph
Publication type:
Article
Impact of a Hospitalwide Increase in Empiric Pediatric Vancomycin Dosing on Initial Trough Concentrations.
Published in:
Pharmacotherapy, 2011, v. 31, n. 9, p. 871, doi. 10.1592/phco.31.9.871
By:
- Frymoyer, Adam;
- Guglielmo, B. Joseph;
- Wilson, Stephen D.;
- Scarpace, Sarah B.;
- Benet, Leslie Z.;
- Hersh, Adam L.
Publication type:
Article
Application of Population Pharmacokinetic Modeling for Individualized Infliximab Dosing Strategies in Crohn Disease.
Published in:
2017
By:
- Frymoyer, Adam;
- Hoekman, Daniël R.;
- Piester, Travis L.;
- de Meij, Tim G.;
- Hummel, Thalia Z.;
- Benninga, Marc A.;
- Kindermann, Angelika;
- Park, K. T.
Publication type:
journal article
Infliximab Dosing Strategies and Predicted Trough Exposure in Children With Crohn Disease.
Published in:
2016
By:
- Frymoyer, Adam;
- Piester, Travis L.;
- Park, K. T.
Publication type:
journal article
Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set.
Published in:
Clinical Pharmacokinetics, 2023, v. 62, n. 1, p. 67, doi. 10.1007/s40262-022-01185-4
By:
- Hughes, Jasmine H.;
- Tong, Dominic M. H.;
- Faldasz, Jonathan D.;
- Frymoyer, Adam;
- Keizer, Ron J.
Publication type:
Article
An Evaluation of Vancomycin Area Under the Curve Estimation Methods for Children Treated for Acute Pulmonary Exacerbations of Cystic Fibrosis Due to Methicillin‐Resistant Staphylococcus aureus.
Published in:
Journal of Clinical Pharmacology, 2019, v. 59, n. 2, p. 198, doi. 10.1002/jcph.1323
By:
- Stockmann, Chris;
- Olson, Jared;
- Rashid, Jahidur;
- Lubsch, Lisa;
- Young, David C.;
- Hersh, Adam L.;
- Frymoyer, Adam;
- Ampofo, Krow;
- Liu, Xiaoxi;
- Wang, Yuhuan;
- Sherwin, Catherine M.T.;
- Zobell, Jeffery T.
Publication type:
Article
4-Methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.
Published in:
Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00123
By:
- Nagy, Nadine;
- Kuipers, Hedwich F.;
- Frymoyer, Adam R.;
- Ishak, Heather D.;
- Bollyky, Jennifer B.;
- Wight, Thomas N.;
- Bollyky, Paul L.
Publication type:
Article

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