Found: 7

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  • Identification of a New Chemical Class of Antimalarials.

    Published in:
    Journal of Infectious Diseases, 2012, v. 206, n. 5, p. 735, doi. 10.1093/infdis/jis418
    By:
    • Brunner, Ralf;
    • Aissaoui, Hamed;
    • Boss, Christoph;
    • Bozdech, Zbynek;
    • Brun, Reto;
    • Corminboeuf, Olivier;
    • Delahaye, Stephane;
    • Fischli, Christoph;
    • Heidmann, Bibia;
    • Kaiser, Marcel;
    • Kamber, Jolanda;
    • Meyer, Solange;
    • Papastogiannidis, Petros;
    • Siegrist, Romain;
    • Voss, Till;
    • Welford, Richard;
    • Wittlin, Sergio;
    • Binkert, Christoph
    Publication type:
    Article

  • Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum.

    Published in:
    Science Translational Medicine, 2019, v. 11, n. 510, p. 1, doi. 10.1126/scitranslmed.aas9917
    By:
    • Schalkwijk, Joost;
    • Allman, Erik L.;
    • Jansen, Patrick A. M.;
    • de Vries, Laura E.;
    • Verhoef, Julie M. J.;
    • Jackowski, Suzanne;
    • Botman, Peter N. M.;
    • Beuckens-Schortinghuis, Christien A.;
    • Koolen, Karin M. J.;
    • Bolscher, Judith M.;
    • Vos, Martijn W.;
    • Miller, Karen;
    • Reeves, Stacy A.;
    • Pett, Helmi;
    • Trevitt, Graham;
    • Wittlin, Sergio;
    • Scheurer, Christian;
    • Sax, Sibylle;
    • Fischli, Christoph;
    • Angulo-Barturen, Iñigo
    Publication type:
    Article

  • Translation of liver stage activity of M5717, a Plasmodium elongation factor 2 inhibitor: from bench to bedside.

    Published in:
    Malaria Journal, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12936-022-04171-0
    By:
    • Khandelwal, Akash;
    • Arez, Francisca;
    • Alves, Paula M.;
    • Badolo, Lassina;
    • Brito, Catarina;
    • Fischli, Christoph;
    • Fontinha, Diana;
    • Oeuvray, Claude;
    • Prudêncio, Miguel;
    • Rottmann, Matthias;
    • Wilkins, Justin;
    • Yalkinoglu, Özkan;
    • Bagchus, Wilhelmina M.;
    • Spangenberg, Thomas
    Publication type:
    Article

  • Targeting Plasmodium PI(4)K to eliminate malaria.

    Published in:
    Nature, 2013, v. 504, n. 7479, p. 248, doi. 10.1038/nature12782
    By:
    • McNamara, Case W.;
    • Lee, Marcus C. S.;
    • Lim, Chek Shik;
    • Lim, Siau Hoi;
    • Roland, Jason;
    • Nagle, Advait;
    • Simon, Oliver;
    • Yeung, Bryan K. S.;
    • Chatterjee, Arnab K.;
    • McCormack, Susan L.;
    • Manary, Micah J.;
    • Zeeman, Anne-Marie;
    • Dechering, Koen J.;
    • Kumar, T. R. Santha;
    • Henrich, Philipp P.;
    • Gagaring, Kerstin;
    • Ibanez, Maureen;
    • Kato, Nobutaka;
    • Kuhen, Kelli L.;
    • Fischli, Christoph
    Publication type:
    Article

  • Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.

    Published in:
    2016
    By:
    • Le Bihan, Amélie;
    • de Kanter, Ruben;
    • Angulo-Barturen, Iñigo;
    • Binkert, Christoph;
    • Boss, Christoph;
    • Brun, Reto;
    • Brunner, Ralf;
    • Buchmann, Stephan;
    • Burrows, Jeremy;
    • Dechering, Koen J.;
    • Delves, Michael;
    • Ewerling, Sonja;
    • Ferrer, Santiago;
    • Fischli, Christoph;
    • Gamo–Benito, Francisco Javier;
    • Gnädig, Nina F.;
    • Heidmann, Bibia;
    • Jiménez-Díaz, María Belén;
    • Leroy, Didier;
    • Martínez, Maria Santos
    Publication type:
    journal article

  • Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.

    Published in:
    ChemMedChem, 2016, v. 11, n. 18, p. 1995, doi. 10.1002/cmdc.201600298
    By:
    • Boss, Christoph;
    • Aissaoui, Hamed;
    • Amaral, Nathalie;
    • Bauer, Aude;
    • Bazire, Stephanie;
    • Binkert, Christoph;
    • Brun, Reto;
    • Bürki, Cédric;
    • Ciana, Claire‐Lise;
    • Corminboeuf, Olivier;
    • Delahaye, Stephane;
    • Dollinger, Claire;
    • Fischli, Christoph;
    • Fischli, Walter;
    • Flock, Alexandre;
    • Frantz, Marie‐Céline;
    • Girault, Malory;
    • Grisostomi, Corinna;
    • Friedli, Astrid;
    • Heidmann, Bibia
    Publication type:
    Article

  • Back Cover: Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action (ChemMedChem 18/2016).

    Published in:
    ChemMedChem, 2016, v. 11, n. 18, p. 2096, doi. 10.1002/cmdc.201600436
    By:
    • Boss, Christoph;
    • Aissaoui, Hamed;
    • Amaral, Nathalie;
    • Bauer, Aude;
    • Bazire, Stephanie;
    • Binkert, Christoph;
    • Brun, Reto;
    • Bürki, Cédric;
    • Ciana, Claire‐Lise;
    • Corminboeuf, Olivier;
    • Delahaye, Stephane;
    • Dollinger, Claire;
    • Fischli, Christoph;
    • Fischli, Walter;
    • Flock, Alexandre;
    • Frantz, Marie‐Céline;
    • Girault, Malory;
    • Grisostomi, Corinna;
    • Friedli, Astrid;
    • Heidmann, Bibia
    Publication type:
    Article