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Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer.
- Published in:
- Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.583333
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- Publication type:
- Article
Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.
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- Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00944-5
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- Publication type:
- Article
A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab.
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- Biomarker Research, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40364-019-0164-0
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- Publication type:
- Article
Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways.
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- Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02363-6
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- Publication type:
- Article
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.
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- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01218-y
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- Publication type:
- Article
Expression Microarray Analysis Reveals Alternative Splicing of <i>LAMA3</i> and <i>DST</i> Genes in Head and Neck Squamous Cell Carcinoma.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091263
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- Publication type:
- Article
Preferential Activation of the Hedgehog Pathway by Epigenetic Modulations in HPV Negative HNSCC Identified with Meta-Pathway Analysis.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078127
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- Publication type:
- Article
Quantifying the Dynamics of Coupled Networks of Switches and Oscillators.
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- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029497
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- Article
Publisher Correction: Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
- Published in:
- 2019
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- Correction Notice
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09937-w
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- Publication type:
- Article
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09937-w
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- Publication type:
- Article
Ten quick tips for deep learning in biology.
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- PLoS Computational Biology, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.pcbi.1009803
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- Publication type:
- Article
Differentially Methylated Super-Enhancers Regulate Target Gene Expression in Human Cancer.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51018-x
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- Publication type:
- Article
Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing.
- Published in:
- PLoS ONE, 2020, p. 1, doi. 10.1371/journal.pone.0233380
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- Publication type:
- Article
A field guide to cultivating computational biology.
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- PLoS Biology, 2021, v. 19, n. 10, p. 1, doi. 10.1371/journal.pbio.3001419
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- Publication type:
- Article
Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology.
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- Briefings in Bioinformatics, 2024, v. 25, n. 5, p. 1, doi. 10.1093/bib/bbae421
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- Publication type:
- Article
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.
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- Briefings in Bioinformatics, 2024, v. 25, n. 3, p. 1, doi. 10.1093/bib/bbae131
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- Publication type:
- Article
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
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- Nature Communications, 2014, v. 5, n. 9, p. 4715, doi. 10.1038/ncomms5715
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- Publication type:
- Article
Functional normalization of 450k methylation array data improves replication in large cancer studies.
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- Genome Biology, 2014, v. 15, n. 12, p. 503, doi. 10.1186/s13059-014-0503-2
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- Publication type:
- Article
Comparative mutational landscape analysis of patient-derived tumour xenografts.
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- 2017
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- Publication type:
- journal article
OutSplice: A Novel Tool for the Identification of Tumor-Specific Alternative Splicing Events.
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- BioMedInformatics, 2023, v. 3, n. 4, p. 853, doi. 10.3390/biomedinformatics3040053
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- Publication type:
- Article
Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening.
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- International Journal of Oncology, 2016, v. 49, n. 1, p. 225, doi. 10.3892/ijo.2016.3532
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- Publication type:
- Article
Generating colorblind- friendly scatter plots for single- cell data.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.82128
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- Publication type:
- Article
Characterization of functionally active gene fusions in human papillomavirus related oropharyngeal squamous cell carcinoma.
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- International Journal of Cancer, 2016, v. 139, n. 2, p. 373, doi. 10.1002/ijc.30081
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- Publication type:
- Article
NF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma.
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- International Journal of Cancer, 2015, v. 137, n. 8, p. 1879, doi. 10.1002/ijc.29558
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- Publication type:
- Article
Correction: Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.
- Published in:
- 2020
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- Publication type:
- corrected article
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.
- Published in:
- British Journal of Cancer, 2020, v. 123, n. 1, p. 101, doi. 10.1038/s41416-020-0851-5
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- Publication type:
- Article
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.
- Published in:
- 2020
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- Publication type:
- journal article
Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes.
- Published in:
- Scientific Reports, 2015, p. 12133, doi. 10.1038/srep12133
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- Publication type:
- Article
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets.
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- Nucleic Acids Research, 2020, v. 48, n. 12, p. e68, doi. 10.1093/nar/gkaa349
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- Publication type:
- Article
Evaluation of a Strategy for the Assimilation of Satellite Radiance Observations with the Local Ensemble Transform Kalman Filter.
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- Monthly Weather Review, 2011, v. 139, n. 6, p. 1932, doi. 10.1175/2010MWR3515.1
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- Publication type:
- Article
A Random Forest Genomic Classifier for Tumor Agnostic Prediction of Response to Anti-PD1 Immunotherapy.
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- Cancer Informatics, 2022, v. 21, p. 1, doi. 10.1177/11769351221136081
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- Publication type:
- Article
Toward Signaling-Driven Biomarkers Immune to Normal Tissue Contamination.
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- Cancer Informatics, 2016, n. 15, p. 15, doi. 10.4137/CIN.S32468
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- Publication type:
- Article
Learning Dysregulated Pathways in Cancers from Differential Variability Analysis.
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- Cancer Informatics, 2014, n. 13, p. 61, doi. 10.4137/CIN.S14066
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- Publication type:
- Article
Hypoxia induces ROS-resistant memory upon reoxygenation in vivo promoting metastasis in part via MUC1-C.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51995-2
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- Publication type:
- Article
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin.
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- Science Translational Medicine, 2022, v. 14, n. 656, p. 1, doi. 10.1126/scitranslmed.abn7571
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- Publication type:
- Article
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis.
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- Briefings in Functional Genomics, 2018, v. 17, n. 1, p. 49, doi. 10.1093/bfgp/elx018
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- Publication type:
- Article
Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS.
- Published in:
- Nature Protocols, 2023, v. 18, n. 12, p. 3690, doi. 10.1038/s41596-023-00892-x
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- Publication type:
- Article
Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma.
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- BMC Genomics, 2012, v. 13, n. 1, p. 160, doi. 10.1186/1471-2164-13-160
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- Publication type:
- Article
CancerInSilico: An R/Bioconductor package for combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer.
- Published in:
- PLoS Computational Biology, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.pcbi.1006935
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- Publication type:
- Article
Age‐associated Senescent – T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response.
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- Advanced Materials, 2024, v. 36, n. 43, p. 1, doi. 10.1002/adma.202310476
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- Publication type:
- Article
projectR: an R/Bioconductor package for transfer learning via PCA, NMF, correlation and clustering.
- Published in:
- Bioinformatics, 2020, v. 36, n. 11, p. 3592, doi. 10.1093/bioinformatics/btaa183
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- Publication type:
- Article
StereoGene: rapid estimation of genome-wide correlation of continuous or interval feature data.
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- Bioinformatics, 2017, v. 33, n. 20, p. 3158, doi. 10.1093/bioinformatics/btx379
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- Publication type:
- Article
PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF.
- Published in:
- Bioinformatics, 2017, v. 33, n. 12, p. 1892, doi. 10.1093/bioinformatics/btx058
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- Publication type:
- Article
switchBox: an R package for k–Top Scoring Pairs classifier development.
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- Bioinformatics, 2015, v. 31, n. 2, p. 273, doi. 10.1093/bioinformatics/btu622
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- Publication type:
- Article
Preserving biological heterogeneity with a permuted surrogate variable analysis for genomics batch correction.
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- Bioinformatics, 2014, v. 30, n. 19, p. 2757, doi. 10.1093/bioinformatics/btu375
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- Publication type:
- Article
CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data.
- Published in:
- Bioinformatics, 2010, v. 26, n. 21, p. 2792, doi. 10.1093/bioinformatics/btq503
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- Publication type:
- Article
Model-informed experimental design recommendations for distinguishing intrinsic and acquired targeted therapeutic resistance in head and neck cancer.
- Published in:
- NPJ Systems Biology & Applications, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41540-022-00244-7
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- Publication type:
- Article
Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma.
- Published in:
- NPJ Systems Biology & Applications, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41540-019-0107-2
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- Publication type:
- Article
Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance.
- Published in:
- Genome Medicine, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13073-018-0545-2
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- Publication type:
- Article