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Enhanced radiation sensitivity, decreased DNA damage repair, and differentiation defects in airway stem cells derived from patients with chronic obstructive pulmonary disease.
- Published in:
- Stem Cells Translational Medicine, 2024, v. 13, n. 9, p. 927, doi. 10.1093/stcltm/szae043
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- Publication type:
- Article
Synergistic Roles of Non-Homologous End Joining and Homologous Recombination in Repair of Ionizing Radiation-Induced DNA Double Strand Breaks in Mouse Embryonic Stem Cells.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 17, p. 1462, doi. 10.3390/cells13171462
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- Publication type:
- Article
Gene Expression Analysis Reveals Inhibition of Radiation- Induced TGFβ-Signaling by Hyperbaric Oxygen Therapy in Mouse Salivary Glands.
- Published in:
- Molecular Medicine, 2014, v. 21, n. 2, p. 257, doi. 10.2119/molmed.2014.00003
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- Publication type:
- Article
ATP-dependent and independent functions of Rad54 in genome maintenance.
- Published in:
- Journal of Cell Biology, 2011, v. 192, n. 5, p. 735, doi. 10.1083/jcb.201011025
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- Publication type:
- Article
UTF1 is a chromatin-associated protein involved in ES cell differentiation.
- Published in:
- Journal of Cell Biology, 2007, v. 178, n. 6, p. 913, doi. 10.1083/jcb.200702058
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- Publication type:
- Article
Homologous and non‐homologous recombination differentially affect DNA damage repair in mice.
- Published in:
- EMBO Journal, 2000, v. 19, n. 7, p. 1703, doi. 10.1093/emboj/19.7.1703
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- Publication type:
- Article
Homologous and non-homologous recombination differentially affect DNA damage repair in mice.
- Published in:
- EMBO Journal, 2000, v. 19, n. 7, p. 1703, doi. 10.1093/emboj/19.7.1703
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- Publication type:
- Article
Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 438, doi. 10.3390/ijms23010438
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- Publication type:
- Article
In Vivo Renin Activity Imaging in the Kidney of Progeroid Ercc1 Mutant Mice.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12433, doi. 10.3390/ijms222212433
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- Publication type:
- Article
Comparison of High- and Low-LET Radiation-Induced DNA Double-Strand Break Processing in Living Cells.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6602, doi. 10.3390/ijms21186602
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- Publication type:
- Article
DNA double-strand breaks are not sufficient to initiate recruitment of TRF2.
- Published in:
- 2007
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- Publication type:
- Letter
Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003431
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- Publication type:
- Article
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks.
- Published in:
- Nature Structural & Molecular Biology, 2007, v. 14, n. 11, p. 1096, doi. 10.1038/nsmb1313
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- Publication type:
- Article
DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.738230
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- Publication type:
- Article
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
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- Journal of Cachexia, Sarcopenia & Muscle, 2019, v. 10, n. 3, p. 662, doi. 10.1002/jcsm.12404
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- Publication type:
- Article
Evaluation of a Fluorescent and Radiolabeled Hybrid Somatostatin Analog In Vitro and in Mice Bearing H69 Neuroendocrine Xenografts.
- Published in:
- Journal of Nuclear Medicine, 2016, v. 57, n. 8, p. 1289, doi. 10.2967/jnumed.115.164970
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- Publication type:
- Article
Transforming Growth Factor-β and the Renin-Angiotensin System in Syndromic Thoracic Aortic Aneurysms: Implications for Treatment.
- Published in:
- Cardiovascular Drugs & Therapy, 2021, v. 35, n. 6, p. 1233, doi. 10.1007/s10557-020-07116-4
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- Publication type:
- Article
BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24871-6
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- Publication type:
- Article
Absence of Cardiovascular Manifestations in a Haploinsufficient Tgfbr1 Mouse Model.
- Published in:
- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089749
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- Publication type:
- Article
In vivo Importance of Homologous Recombination DNA Repair for Mouse Neural Stem and Progenitor Cells.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037194
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- Publication type:
- Article
Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT<sub>1</sub>) Receptor Blockade.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023411
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- Publication type:
- Article
Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice.
- Published in:
- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012112
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- Publication type:
- Article
Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome.
- Published in:
- Journal of Pathology, 2017, v. 243, n. 3, p. 294, doi. 10.1002/path.4949
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- Publication type:
- Article
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner.
- Published in:
- PLoS Genetics, 2020, v. 16, n. 1, p. 1, doi. 10.1371/journal.pgen.1008550
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- Publication type:
- Article
Imaging preclinical tumour models: improving translational power.
- Published in:
- Nature Reviews Cancer, 2014, v. 14, n. 7, p. 481, doi. 10.1038/nrc3751
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- Publication type:
- Article
The structure-specific endonuclease Mus81–Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks.
- Published in:
- EMBO Journal, 2006, v. 25, n. 20, p. 4921, doi. 10.1038/sj.emboj.7601344
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- Publication type:
- Article
Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
- Published in:
- EMBO Journal, 2004, v. 23, n. 17, p. 3548, doi. 10.1038/sj.emboj.7600353
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- Publication type:
- Article
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.
- Published in:
- EMBO Journal, 2003, v. 22, n. 22, p. 6137, doi. 10.1093/emboj/cdg580
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- Publication type:
- Article
Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.
- Published in:
- EMBO Journal, 2002, v. 21, n. 8, p. 2030, doi. 10.1093/emboj/21.8.2030
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- Publication type:
- Article
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.
- Published in:
- EMBO Journal, 2001, v. 20, n. 22, p. 6540, doi. 10.1093/emboj/20.22.6540
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- Publication type:
- Article
Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice.
- Published in:
- NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00154-4
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- Publication type:
- Article
Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice.
- Published in:
- Multidisciplinary Respiratory Medicine, 2017, v. 12, p. 1, doi. 10.1186/s40248-017-0089-0
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- Publication type:
- Article
Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 13, p. 6475, doi. 10.1093/nar/gkt375
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- Publication type:
- Article
Automated analysis of time-lapse fluorescence microscopy images: from live cell images to intracellular foci.
- Published in:
- Bioinformatics, 2010, v. 26, n. 19, p. 2424, doi. 10.1093/bioinformatics/btq434
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- Publication type:
- Article
Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation.
- Published in:
- Nucleic Acids Research, 2010, v. 38, n. 10, p. 3245, doi. 10.1093/nar/gkq069
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- Publication type:
- Article
Induction of linear tracks of DNA double-strand breaks by α-particle irradiation of cells.
- Published in:
- Nature Methods, 2008, v. 5, n. 3, p. 261, doi. 10.1038/nmeth.f.206
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- Publication type:
- Article
Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation.
- Published in:
- Human Molecular Genetics, 2024, v. 33, n. 12, p. 1090, doi. 10.1093/hmg/ddae044
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- Publication type:
- Article
Molecular phenotyping and functional assessment of smooth muscle-like cells with pathogenic variants in aneurysm genes ACTA2, MYH11, SMAD3 and FBN1.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 24, p. 2286, doi. 10.1093/hmg/ddab190
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- Publication type:
- Article
Molecular phenotyping and functional assessment of smooth muscle-like cells with pathogenic variants in aneurysm genes ACTA2, MYH11, SMAD3 and FBN1.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 23, p. 2286, doi. 10.1093/hmg/ddab190
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- Publication type:
- Article
Slc2a10 knock-out mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 9, p. 1476, doi. 10.1093/hmg/ddaa071
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- Publication type:
- Article
Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1<sup>Δ/−</sup> mice.
- Published in:
- Clinical Science, 2017, v. 131, n. 15, p. 1941, doi. 10.1042/CS20170026
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- Publication type:
- Article
Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice.
- Published in:
- Molecular Imaging & Biology, 2024, v. 26, n. 4, p. 628, doi. 10.1007/s11307-024-01902-4
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- Publication type:
- Article
Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response.
- Published in:
- Aging Cell, 2024, v. 23, n. 5, p. 1, doi. 10.1111/acel.14126
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- Publication type:
- Article
Elucidating the Influence of Tumor Presence on the Polymersome Circulation Time in Mice.
- Published in:
- Pharmaceutics, 2019, v. 11, n. 5, p. 241, doi. 10.3390/pharmaceutics11050241
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- Publication type:
- Article