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A Systematic Approach to Optimize the Implementation of Precision Oncology in Clinical Practice: A Meeting Proceeding.
Published in:
Journal of Immunotherapy & Precision Oncology, 2024, v. 7, n. 3, p. 210, doi. 10.36401/JIPO-23-41
By:
- Jazieh, Abdul Rahman;
- El Rouby, Nihal;
- Guinigundo, Andrew;
- Huelsman, Karen M.;
- Curran, Emily;
- Khan, Rafiullah;
- Grund, Jaime;
- Calvo, Alejandro R.;
- Claes, Jason J.;
- Overton, Sarah C.;
- Hellard, Sally;
- Vasiliadis, Leah;
- Liu, Minetta;
- Blaxall, Burns C.
Publication type:
Article
Machine Learning for Prediction of Stable Warfarin Dose in US Latinos and Latin Americans.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.749786
By:
- Steiner, Heidi E.;
- Giles, Jason B.;
- Patterson, Hayley Knight;
- Feng, Jianglin;
- El Rouby, Nihal;
- Claudio, Karla;
- Marcatto, Leiliane Rodrigues;
- Tavares, Leticia Camargo;
- Galvez, Jubby Marcela;
- Calderon-Ospina, Carlos-Alberto;
- Sun, Xiaoxiao;
- Hutz, Mara H.;
- Scott, Stuart A.;
- Cavallari, Larisa H.;
- Fonseca-Mendoza, Dora Janeth;
- Duconge, Jorge;
- Botton, Mariana Rodrigues;
- Santos, Paulo Caleb Junior Lima;
- Karnes, Jason H.
Publication type:
Article
Atenolol Induced HDL-C Change in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076984
By:
- McDonough, Caitrin W.;
- Gillis, Nancy K.;
- Alsultan, Abdullah;
- Chang, Shin-Wen;
- Kawaguchi-Suzuki, Marina;
- Lang, Jason E.;
- Shahin, Mohamed Hossam A.;
- Buford, Thomas W.;
- El Rouby, Nihal M.;
- Sá, Ana C.C.;
- Langaee, Taimour Y.;
- Gums, John G.;
- Chapman, Arlene B.;
- Cooper-DeHoff, Rhonda M.;
- Turner, Stephen T.;
- Gong, Yan;
- Johnson, Julie A.
Publication type:
Article
Evaluation of FDA Boxed Warning on Prescribing Patterns of Fluoroquinolones for Uncomplicated Urinary Tract Infections.
Published in:
2019
By:
- Cowart, Kevin;
- Worley, Marylee;
- Rouby, Nihal El;
- Sando, Karen
Publication type:
journal article
Vascular Smooth Muscle Cells From Hypertensive Patient-Derived Induced Pluripotent Stem Cells to Advance Hypertension Pharmacogenomics.
Published in:
Stem Cells Translational Medicine, 2015, v. 4, n. 12, p. 1380, doi. 10.5966/sctm.2015-0126
By:
- BIEL, NIKOLETT M.;
- SANTOSTEFANO, KATHERINE E.;
- DIVITA, BAYLI B.;
- ROUBY, NIHAL EL;
- CARRASQUILLA, SANTIAGO D.;
- SIMMONS, CHELSEY;
- NAKANISHI, MAHITO;
- COOPER-DEHOFF, RHONDA M.;
- JOHNSON, JULIE A.;
- TERADA, NAOHIRO
Publication type:
Article
Concise Review: Induced Pluripotent Stem Cell Research in the Era of Precision Medicine.
Published in:
Stem Cells, 2017, v. 35, n. 3, p. 545, doi. 10.1002/stem.2570
By:
- Hamazaki, Takashi;
- El Rouby, Nihal;
- Fredette, Natalie C.;
- Santostefano, Katherine E.;
- Terada, Naohiro
Publication type:
Article
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 3, p. 723, doi. 10.1002/cpt.2355
By:
- McDonough, Caitrin W.;
- Warren, Helen R.;
- Jack, John R.;
- Motsinger‐Reif, Alison A.;
- Armstrong, Nicole D.;
- Bis, Joshua C.;
- House, John S.;
- Singh, Sonal;
- El Rouby, Nihal M.;
- Gong, Yan;
- Mychaleckyj, Joesyf C.;
- Rotroff, Daniel M.;
- Benavente, Oscar R.;
- Caulfield, Mark J.;
- Doria, Alessandrio;
- Pepine, Carl J.;
- Psaty, Bruce M.;
- Glorioso, Valeria;
- Glorioso, Nicola;
- Hiltunen, Timo P.
Publication type:
Article
Opportunity for Genotype‐Guided Prescribing Among Adult Patients in 11 US Health Systems.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 1, p. 179, doi. 10.1002/cpt.2161
By:
- Hicks, J. Kevin;
- El Rouby, Nihal;
- Ong, Henry H.;
- Schildcrout, Jonathan S.;
- Ramsey, Laura B.;
- Shi, Yaping;
- Anne Tang, Leigh;
- Aquilante, Christina L.;
- Beitelshees, Amber L.;
- Blake, Kathryn V.;
- Cimino, James J.;
- Davis, Brittney H.;
- Empey, Philip E.;
- Kao, David P.;
- Lemkin, Daniel L.;
- Limdi, Nita A.;
- P. Lipori, Gloria;
- Rosenman, Marc B.;
- Skaar, Todd C.;
- Teal, Evgenia
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1417, doi. 10.1002/cpt.2015
By:
- Lima, John J.;
- Thomas, Cameron D.;
- Barbarino, Julia;
- Desta, Zeruesenay;
- Van Driest, Sara L.;
- El Rouby, Nihal;
- Johnson, Julie A.;
- Cavallari, Larisa H.;
- Shakhnovich, Valentina;
- Thacker, David L.;
- Scott, Stuart A.;
- Schwab, Matthias;
- Uppugunduri, Chakradhara Rao S.;
- Formea, Christine M.;
- Franciosi, James P.;
- Sangkuhl, Katrin;
- Gaedigk, Andrea;
- Klein, Teri E.;
- Gammal, Roseann S.;
- Furuta, Takahisa
Publication type:
Article
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype‐Derived Activity Scores.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 12, p. 678, doi. 10.1002/psp4.12563
By:
- Thomas, Cameron D.;
- Mosley, Scott A.;
- Kim, Sarah;
- Lingineni, Karthik;
- El Rouby, Nihal;
- Langaee, Taimour Y.;
- Gong, Yan;
- Wang, Danxin;
- Schmidt, Siegfried O.;
- Binkley, Philip F.;
- Estores, David S.;
- Feng, Kairui;
- Kim, Hyewon;
- Kinjo, Minori;
- Li, Zhichuan;
- Fang, Lanyan;
- Chapman, Arlene B.;
- Cooper-DeHoff, Rhonda M.;
- Gums, John G.;
- Hamadeh, Issam S.
Publication type:
Article
Genome-Wide Meta-Analysis of Blood Pressure Response to β<sub>1</sub>-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).
Published in:
2019
By:
- Singh, Sonal;
- Warren, Helen R.;
- Hiltunen, Timo P.;
- McDonough, Caitrin W.;
- El Rouby, Nihal;
- Salvi, Erika;
- Zhiying Wang;
- Garofalidou, Tatiana;
- Fyhrquist, Frej;
- Kontula, Kimmo K.;
- Glorioso, Valeria;
- Zaninello, Roberta;
- Glorioso, Nicola;
- Pepine, Carl J.;
- Munroe, Patricia B.;
- Turner, Stephan T.;
- Chapman, Arlene B.;
- Boerwinkle, Eric;
- Johnson, Julie A.;
- Yan Gong
Publication type:
journal article
Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension.
Published in:
2014
By:
- Fontana, Vanessa;
- McDonough, Caitrin W.;
- Gong, Yan;
- El Rouby, Nihal M.;
- Sá, Ana Caroline C.;
- Taylor, Kent D.;
- Chen, Y. ‐ D. Ida;
- Gums, John G.;
- Chapman, Arlene B.;
- Turner, Stephen T.;
- Pepine, Carl J.;
- Johnson, Julie A.;
- Cooper ‐ DeHoff, Rhonda M.;
- Sá, Ana Caroline C;
- Chen, Y-D Ida;
- Cooper-DeHoff, Rhonda M
Publication type:
journal article
Genome-wide study of resistant hypertension identified from electronic health records.
Published in:
PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171745
By:
- Dumitrescu, Logan;
- Ritchie, Marylyn D.;
- Denny, Joshua C.;
- El Rouby, Nihal M.;
- McDonough, Caitrin W.;
- Bradford, Yuki;
- Ramirez, Andrea H.;
- Bielinski, Suzette J.;
- Basford, Melissa A.;
- Chai, High Seng;
- Peissig, Peggy;
- Carrell, David;
- Pathak, Jyotishman;
- Rasmussen, Luke V.;
- Wang, Xiaoming;
- Pacheco, Jennifer A.;
- Kho, Abel N.;
- Hayes, M. Geoffrey;
- Matsumoto, Martha;
- Smith, Maureen E.
Publication type:
Article
Genetics of Resistant Hypertension: a Novel Pharmacogenomics Phenotype.
Published in:
Current Hypertension Reports, 2015, v. 17, n. 9, p. 1, doi. 10.1007/s11906-015-0583-8
By:
- El Rouby, Nihal;
- Cooper-DeHoff, Rhonda M.
Publication type:
Article
Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients.
Published in:
JAMA Network Open, 2020, v. 3, n. 12, p. e2029411, doi. 10.1001/jamanetworkopen.2020.29411
By:
- Ramsey, Laura B.;
- Ong, Henry H.;
- Schildcrout, Jonathan S.;
- Shi, Yaping;
- Tang, Leigh Anne;
- Hicks, J. Kevin;
- El Rouby, Nihal;
- Cavallari, Larisa H.;
- Tuteja, Sony;
- Aquilante, Christina L.;
- Beitelshees, Amber L.;
- Lemkin, Daniel L.;
- Blake, Kathryn V.;
- Williams, Helen;
- Cimino, James J.;
- Davis, Brittney H.;
- Limdi, Nita A.;
- Empey, Philip E.;
- Horvat, Christopher M.;
- Kao, David P.
Publication type:
Article
β<sub>2</sub>‐Adrenergic Receptor Gene Affects the Heart Rate Response of β‐Blockers: Evidence From 3 Clinical Studies.
Published in:
Journal of Clinical Pharmacology, 2019, v. 59, n. 11, p. 1462, doi. 10.1002/jcph.1443
By:
- Shahin, Mohamed H.;
- Rouby, Nihal El;
- Conrado, Daniela J.;
- Gonzalez, Daniel;
- Gong, Yan;
- Lobmeyer, Maximilian T.;
- Beitelshees, Amber L.;
- Boerwinkle, Eric;
- Gums, John G.;
- Chapman, Arlene;
- Turner, Stephen T.;
- Pepine, Carl J.;
- Cooper‐DeHoff, Rhonda M.;
- Johnson, Julie A.
Publication type:
Article
Reply to "A call for reporting of tumor‐specific outcomes in studies of DPYD genotyping".
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.70008
By:
- El Rouby, Nihal;
- Allen, Josiah D.;
- Muldoon, Megan;
- Beck, Mollie;
- Hesse, Kristina;
- Sebree, Nichlas;
- Yoder, Robin;
- Ritter, Stacey;
- Alqahtani, Zuhair;
- Grund, Jaime;
- Holbrook, Brooke Philips
Publication type:
Article
Pharmacogenomics polygenic risk score: Ready or not for prime time?
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.13893
By:
- Singh, Sonal;
- Stocco, Gabriele;
- Theken, Katherine N.;
- Dickson, Alyson;
- Feng, QiPing;
- Karnes, Jason H.;
- Mosley, Jonathan D.;
- El Rouby, Nihal
Publication type:
Article
Real‐world implementation of DPYD and UGT1A1 pharmacogenetic testing in a community‐based cancer center.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 2, p. 1, doi. 10.1111/cts.13704
By:
- Muldoon, Megan;
- Beck, Mollie;
- Sebree, Nichlas;
- Yoder, Robin;
- Ritter, Stacey;
- Allen, Josiah D.;
- Alqahtani, Zuhair;
- Grund, Jaime;
- Philips, Brooke;
- Hesse, Kristina;
- El Rouby, Nihal
Publication type:
Article
A randomized, cross‐over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Published in:
CTS: Clinical & Translational Science, 2022, v. 15, n. 7, p. 1764, doi. 10.1111/cts.13294
By:
- Mosley, Scott A.;
- Kim, Sarah;
- El Rouby, Nihal;
- Lingineni, Karthik;
- Esteban, Valvanera Vozmediano;
- Gong, Yan;
- Chen, Yiqing;
- Estores, David;
- Feng, Kairui;
- Kim, Hyewon;
- Kinjo, Minori;
- Langaee, Taimour;
- Li, Zhichuan;
- Schmidt, Siegfried O. F.;
- Johnson, Julie A.;
- Frye, Reginald F.;
- Fang, Lanyan;
- Zhao, Liang;
- Binkley, Philip F.;
- Schmidt, Stephan
Publication type:
Article
Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations.
Published in:
CTS: Clinical & Translational Science, 2022, v. 15, n. 2, p. 558, doi. 10.1111/cts.13176
By:
- El Rouby, Nihal;
- Shahin, Mohamed H.;
- Bader, Loulia;
- Khalifa, Sherief I.;
- Elewa, Hazem
Publication type:
Article
Multi‐site Investigation of Genetic Determinants of Warfarin Dose Variability in Latinos.
Published in:
CTS: Clinical & Translational Science, 2021, v. 14, n. 1, p. 268, doi. 10.1111/cts.12854
By:
- El Rouby, Nihal;
- Rodrigues Marcatto, Leiliane;
- Claudio, Karla;
- Camargo Tavares, Letícia;
- Steiner, Heidi;
- Botton, Marianna R.;
- Lubitz, Steve A.;
- Fallon, Echo N.;
- Yee, Kevin;
- Kaye, Justin;
- Scott, Stuart A.;
- Karnes, Jason;
- Caleb Junior de Lima Santos, Paulo;
- Duconge, Jorge;
- Cavallari, Larisa H.
Publication type:
Article
Clinical Utility of Pharmacogene Panel‐Based Testing in Patients Undergoing Percutaneous Coronary Intervention.
Published in:
CTS: Clinical & Translational Science, 2020, v. 13, n. 3, p. 473, doi. 10.1111/cts.12729
By:
- El Rouby, Nihal;
- Alrwisan, Adel;
- Langaee, Taimour;
- Lipori, Gloria;
- Angiolillo, Dominick J;
- Franchi, Francesco;
- Riva, Alberto;
- Elsey, Amanda;
- Johnson, Julie A.;
- Cavallari, Larisa H.;
- Winterstein, Almut G.
Publication type:
Article
Effect of Genetic and Nongenetic Factors on the Clinical Response to Mineralocorticoid Receptor Antagonist Therapy in Egyptians with Heart Failure.
Published in:
CTS: Clinical & Translational Science, 2020, v. 13, n. 1, p. 195, doi. 10.1111/cts.12702
By:
- Sarhan, Neven M.;
- Shahin, Mohamed H.;
- El Rouby, Nihal M.;
- El‐Wakeel, Lamia M.;
- Solayman, Mohamed H.;
- Langaee, Taimour;
- Khorshid, Hazem;
- Schaalan, Mona F.;
- Sabri, Nagwa A.;
- Cavallari, Larisa H.
Publication type:
Article
Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta‐Blockers in European Americans.
Published in:
CTS: Clinical & Translational Science, 2019, v. 12, n. 5, p. 497, doi. 10.1111/cts.12643
By:
- Singh, Sonal;
- El Rouby, Nihal;
- McDonough, Caitrin W.;
- Gong, Yan;
- Bailey, Kent R.;
- Boerwinkle, Eric;
- Chapman, Arlene B.;
- Gums, John G.;
- Turner, Stephen T.;
- Cooper‐DeHoff, Rhonda M.;
- Johnson, Julie A.
Publication type:
Article

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