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Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial.
- Published in:
- 2018
- By:
- Publication type:
- journal article
A Novel DCTN1 mutation with late-onset parkinsonism and frontotemporal atrophy.
- Published in:
- Movement Disorders, 2014, v. 29, n. 9, p. 1201, doi. 10.1002/mds.25833
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- Publication type:
- Article
Efficacy and safety of oral semaglutide in Japanese patients with type 2 diabetes: A post hoc subgroup analysis of the PIONEER 1, 3, 4 and 8 trials.
- Published in:
- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 12, p. 2785, doi. 10.1111/dom.14536
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- Publication type:
- Article
Long‐term (52‐week) efficacy and safety of dapagliflozin as an adjunct to insulin therapy in Japanese patients with type 1 diabetes: Subgroup analysis of the DEPICT‐2 study.
- Published in:
- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 7, p. 1496, doi. 10.1111/dom.14362
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- Publication type:
- Article
Long‐term efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: pooled 52‐week outcomes from the DEPICT‐1 and ‐2 studies.
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- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 2, p. 549, doi. 10.1111/dom.14248
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- Publication type:
- Article
Long‐term efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (the DEPICT‐2 study): 52‐week results from a randomized controlled trial.
- Published in:
- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 9, p. 1516, doi. 10.1111/dom.14060
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- Publication type:
- Article
Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT‐5): 52‐week results from a randomized, open‐label, phase III clinical trial.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 4, p. 540, doi. 10.1111/dom.13922
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- Publication type:
- Article
Superior efficacy with a fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with insulin degludec and liraglutide in insulin‐naïve Japanese patients with type 2 diabetes in a phase 3, open‐label, randomized trial
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2674, doi. 10.1111/dom.13856
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- Publication type:
- Article
Superior efficacy with a fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with insulin degludec and liraglutide in insulin‐naïve Japanese patients with type 2 diabetes in a phase 3, open‐label, randomized trial
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2674, doi. 10.1111/dom.13856
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- Publication type:
- Article
Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52‐week data from the PROVIDE study.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 7, p. 1737, doi. 10.1111/dom.13686
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- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of dapagliflozin in combination with insulin in Japanese patients with type 1 diabetes.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 4, p. 876, doi. 10.1111/dom.13593
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- Publication type:
- Article
Efficacy and safety of dapagliflozin over 1 year as add-on to insulin therapy in Japanese patients with type 2 diabetes: the DAISY (Dapagliflozin Added to patients under InSulin therapY) trial.
- Published in:
- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 4, p. 562, doi. 10.1111/dom.12853
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- Publication type:
- Article
The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes.
- Published in:
- Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1279, doi. 10.1111/dom.12758
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- Publication type:
- Article
The Role of Heat Shock Response in Insulin Resistance and Diabetes.
- Published in:
- Diabetes & Metabolism Journal, 2014, v. 38, n. 2, p. 100, doi. 10.4093/dmj.2014.38.2.100
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- Publication type:
- Article
SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35219-z
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- Publication type:
- Article
Clinical Benefit of Switching from Low-Dose to High-Dose Empagliflozin in Patients with Type 2 Diabetes.
- Published in:
- Diabetes Therapy, 2022, v. 13, n. 9, p. 1621, doi. 10.1007/s13300-022-01296-y
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- Publication type:
- Article
Short-Term Cost-Effectiveness of Switching to Insulin Degludec in Japanese Patients with Type 2 Diabetes Receiving Basal–Bolus Therapy.
- Published in:
- Diabetes Therapy, 2019, v. 10, n. 4, p. 1347, doi. 10.1007/s13300-019-0635-1
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- Publication type:
- Article
Identification of microRNA that represses IRS-1 expression in liver.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191553
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- Publication type:
- Article
Novel function of transthyretin in pancreatic alpha cells
- Published in:
- FEBS Letters, 2012, v. 586, n. 23, p. 4215, doi. 10.1016/j.febslet.2012.10.025
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- Publication type:
- Article
Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy.
- Published in:
- 2003
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- Publication type:
- journal article
Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.
- Published in:
- 1998
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- Publication type:
- journal article
Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling.
- Published in:
- 1997
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- Publication type:
- journal article
Cell-specific regulation of IRS-1 gene expression: role of E box and C/EBP binding site in HepG2 cells and CHO cells.
- Published in:
- 1997
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- Publication type:
- journal article
Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization.
- Published in:
- 1993
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- Publication type:
- journal article
The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report.
- Published in:
- BMC Endocrine Disorders, 2018, v. 18, p. 1, doi. 10.1186/s12902-018-0234-6
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- Publication type:
- Article
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese.
- Published in:
- Journal of Human Genetics, 2004, v. 49, n. 11, p. 629, doi. 10.1007/s10038-004-0199-3
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- Publication type:
- Article
The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling.
- Published in:
- Nature Communications, 2014, v. 5, n. 3, p. 3428, doi. 10.1038/ncomms4428
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- Publication type:
- Article
The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth.
- Published in:
- Nature Communications, 2013, v. 4, n. 1, p. 1398, doi. 10.1038/ncomms2408
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- Publication type:
- Article
Autoimmune Polyglandular Syndrome Type 3 Complicated with IgG4-related Disease.
- Published in:
- Internal Medicine, 2024, v. 63, n. 3, p. 425, doi. 10.2169/internalmedicine.1270-22
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- Publication type:
- Article
29-OR: Regulatory Loop of IR Signaling for Adipocyte Mitochondrial Homeostasis.
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- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-29-OR
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- Publication type:
- Article
1714-P: Regulation of Phosphorylation Status in Insulin Signaling via a4 Is Necessary for Adipocyte Maintenance and Lipid Dynamics.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1714-P
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- Publication type:
- Article
1956-P: Inhibition of Tissue Macrophage Proliferation Improves Insulin Resistance in Liver and Adipose Tissue.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1956-P
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- Publication type:
- Article
1072-P: Activation of Heat Shock Response Ameliorates Nonalcoholic Fatty Liver Disease Biomarkers.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1072-P
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- Publication type:
- Article
142-OR: Unique Role of the a4 Component for S6-Kinase Activity in Metabolic Regulation and Anti-apoptotic Effect in Brown Adipose Tissue.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-142-OR
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- Publication type:
- Article
985-P: Oral Semaglutide as Add-On to Insulin in T2D: PIONEER 8.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-985-P
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- Publication type:
- Article
483-P: Pioglitazone Suppresses Macrophage Proliferation in Apolipoprotein-e Deficient Mice by Activating PPARγ.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-483-P
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- Publication type:
- Article
482-P: Linagliptin Induces M2 Macrophage Polarization and Suppresses Progression of Atherosclerosis in High-Fat-Fed ApoE-Deficient Mice.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-482-P
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- Publication type:
- Article
1863-P: The Hepatic Role of Heat Shock Protein 72 in the Pathogenesis of Type 2 Diabetes.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1863-P
- By:
- Publication type:
- Article
Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis.
- Published in:
- Diabetes, 2012, v. 61, n. 4, p. 838, doi. 10.2337/db11-1098
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- Publication type:
- Article
Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
- Published in:
- Diabetes, 2007, v. 56, p. A599
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- Publication type:
- Article
Irs-1 Transgenic Mice Showed Increased Epididymal Fat Mass and Displayed Insulin Resistance In Vivo.
- Published in:
- Diabetes, 2007, v. 56, p. A346
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- Publication type:
- Article
Mild Electrical Current and Hyperthermia Ameliorates Insulin Resistance and Beta-Cell Function in Mice Models of Type 2 Diabetes.
- Published in:
- Diabetes, 2007, v. 56, p. A65
- By:
- Publication type:
- Article
Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal-Regulating Kinase 1 on Insulin Signaling.
- Published in:
- Diabetes, 2006, v. 55, n. 5, p. 1197, doi. 10.2337/db05-1187
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- Publication type:
- Article
Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis in Human Umbilical Vein Endothelial Cells.
- Published in:
- Diabetes, 2006, v. 55, n. 1, p. 120, doi. 10.2337/diabetes.55.01.06.db05-0943
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- Publication type:
- Article
Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα): Pooled Analysis of Phase 2 and 3 Studies in Dyslipidemic Patients with or without Statin Combination.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 22, p. 5537, doi. 10.3390/ijms20225537
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- Publication type:
- Article
Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 3, p. 706, doi. 10.3390/ijms20030706
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- Publication type:
- Article
Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double‐blind placebo‐controlled clinical trials.
- Published in:
- Cardiovascular Diabetology, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12933-021-01291-w
- By:
- Publication type:
- Article
Long-Term Efficacy and Safety of Linagliptin in a Japanese Population with Type 2 Diabetes Aged ≥ 60 Years Treated with Basal Insulin: A Randomised Trial.
- Published in:
- 2019
- By:
- Publication type:
- journal article
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09418-0
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- Publication type:
- Article
Bradykinin potentiates insulin-stimulated glucose uptake and enhances insulin signal through the bradykinin B<sub>2</sub> receptor in dog skeletal muscle and rat L6 myoblasts.
- Published in:
- European Journal of Endocrinology, 1998, v. 138, n. 3, p. 344
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- Publication type:
- Article