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Generation of synthetic PET images of synaptic density and amyloid from 18F‐FDG images using deep learning.
Published in:
Medical Physics, 2021, v. 48, n. 9, p. 5115, doi. 10.1002/mp.15073
By:
- Wang, Rui;
- Liu, Hui;
- Toyonaga, Takuya;
- Shi, Luyao;
- Wu, Jing;
- Onofrey, John Aaron;
- Tsai, Yu‐Jung;
- Naganawa, Mika;
- Ma, Tianyu;
- Liu, Yaqiang;
- Chen, Ming‐Kai;
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- van Dyck, Christopher H.;
- Carson, Richard E.;
- Liu, Chi
Publication type:
Article
Clinical Trials: New Opportunities.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 7, p. 773, doi. 10.1093/gerona/gls126
By:
- Chapman, Sandra Bond;
- Cotman, Carl W.;
- Fillit, Howard M.;
- Gallagher, Michela;
- van Dyck, Christopher H.
Publication type:
Article
Clinical trials: new opportunities.
Published in:
2012
By:
- Chapman SB;
- Cotman CW;
- Fillit HM;
- Gallagher M;
- van Dyck CH;
- Chapman, Sandra Bond;
- Cotman, Carl W;
- Fillit, Howard M;
- Gallagher, Michela;
- van Dyck, Christopher H
Publication type:
journal article
BDNF Variants, Premorbid Educational Attainment, and Disease Characteristics in Alzheimer's Disease: An Exploratory Study.
Published in:
Journal of Alzheimer's Disease, 2009, v. 17, n. 4, p. 887, doi. 10.3233/JAD-2009-1106
By:
- Zdanys, Kristina F.;
- Kleiman, Timothy G.;
- Zhang, Huiping;
- Ozbay, Fatih;
- MacAvoy, Martha G.;
- Gelernter, Joel;
- Van Dyck, Christopher H.
Publication type:
Article
Adverse effects of methylphenidate for apathy in patients with Alzheimer's disease (ADMET2 trial).
Published in:
International Journal of Geriatric Psychiatry, 2024, v. 39, n. 6, p. 1, doi. 10.1002/gps.6108
By:
- Zeng, Lijuan;
- Perin, Jamie;
- Gross, Alden L.;
- Shade, David;
- Lanctôt, Krista L.;
- Lerner, Alan J.;
- Mintzer, Jacobo E.;
- Brawman‐Mintzer, Olga;
- Padala, Prasad R.;
- van Dyck, Christopher H.;
- Porsteinsson, Anton P.;
- Craft, Suzanne;
- Levey, Allan;
- Herrmann, Nathan;
- Rosenberg, Paul B.
Publication type:
Article
Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease.
Published in:
JAMA: Journal of the American Medical Association, 2000, v. 283, n. 8, p. 1007, doi. 10.1001/jama.283.8.1007
By:
- Mulnard, Ruth A.;
- Cotman, Carl W.;
- Kawas, Claudia;
- Van Dyck, Christopher H.;
- Sano, Mary;
- Doody, Rachelle;
- Koss, Elizabeth;
- Pfeiffer, Eric;
- Jin, Sheia;
- Gamst, Anthony;
- Grundman, Michael;
- Thomas, Ronald;
- Thal, Leon J.
Publication type:
Article
Sex differences in the pleiotropy of hearing difficulty with imaging-derived phenotypes: a brain-wide investigation.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 10, p. 3395, doi. 10.1093/brain/awae077
By:
- He, Jun;
- Cabrera-Mendoza, Brenda;
- Angelis, Flavio De;
- Pathak, Gita A;
- Koller, Dora;
- Curhan, Sharon G;
- Curhan, Gary C;
- Mecca, Adam P;
- Dyck, Christopher H van;
- Polimanti, Renato
Publication type:
Article
CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 10, p. 6860, doi. 10.1002/alz.14152
By:
- Lizama, Britney N.;
- Williams, Claire;
- North, Hilary A.;
- Pandey, Kiran;
- Duong, Duc;
- Di Caro, Valentina;
- Mecca, Adam P.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Levey, Allan I.;
- Grundman, Michael;
- van Dyck, Christopher H.;
- Caggiano, Anthony O.;
- Seyfried, Nicholas T.;
- Hamby, Mary E.
Publication type:
Article
Nanoscale imaging of pT217‐tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early‐stage neurodegeneration.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2843, doi. 10.1002/alz.13737
By:
- Datta, Dibyadeep;
- Perone, Isabella;
- Wijegunawardana, Denethi;
- Liang, Feng;
- Morozov, Yury M.;
- Arellano, Jon;
- Duque, Alvaro;
- Xie, Zhongcong;
- van Dyck, Christopher H.;
- Joyce, Mary Kate P.;
- Arnsten, Amy F. T.
Publication type:
Article
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2698, doi. 10.1002/alz.13735
By:
- Wang, Guoqiao;
- Li, Yan;
- Xiong, Chengjie;
- Benzinger, Tammie L. S.;
- Gordon, Brian A.;
- Hassenstab, Jason;
- Aschenbrenner, Andrew J.;
- McDade, Eric;
- Clifford, David B.;
- Libre‐Guerra, Jorge J.;
- Shi, Xinyu;
- Mummery, Catherine J.;
- van Dyck, Christopher H.;
- Lah, James J.;
- Honig, Lawrence S.;
- Day, Gregg;
- Ringman, John M.;
- Brooks, William S.;
- Fox, Nick C.;
- Suzuki, Kazushi
Publication type:
Article
Blood‐based biomarkers for predicting treatment response in the Apathy in Dementia Methylphenidate Trial 2 randomized clinical trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.079161
By:
- Tumati, Shankar;
- Vieira, Danielle;
- Bawa, Kritleen Kaur;
- Andreazza, Ana C.;
- Mintzer, Jacobo;
- Scherer, Roberta;
- Rosenberg, Paul B.;
- van Dyck, Christopher H;
- Padala, Prasad R;
- Brawman‐Mintzer, Olga;
- Porsteinsson, Anton P.;
- Lerner, Alan J.;
- Craft, Suzanne;
- Levey, Allan I.;
- Burke, William J;
- Perin, Jamie;
- Shade, David;
- Herrmann, Nathan;
- Lanctôt, Krista L.
Publication type:
Article
Natural cubic splines for the analysis of Alzheimer's trials.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.070862
By:
- Donohue, Michael C.;
- Langford, Oliver;
- Insel, Philip S.;
- van Dyck, Christopher H;
- Petersen, Ronald C.;
- Craft, Suzanne;
- Raman, Rema;
- Sims, John R.;
- Sperling, Reisa A.;
- Aisen, Paul S. S
Publication type:
Article
Tau epicenter identification and connectivity in clinically heterogeneous Alzheimer's disease variants.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079435
By:
- Trainer, Anne;
- Xu, Wanwan;
- Chase, Alison;
- O'Dell, Ryan S.;
- Tun, Samantha M;
- Li, Joyce S;
- Ju, Suyeon;
- van Dyck, Christopher H;
- Mecca, Adam P;
- Fredricks, Carolyn
Publication type:
Article
Feasibility Study for Longitudinal Retinal Imaging in the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079580
By:
- Rissman, Robert A;
- Ngolab, Jennifer;
- Donohue, Michael C.;
- Belsha, Alison;
- Salazar, Jennifer;
- Cohen, Paula;
- Jaiswal, Sandhya;
- Tan, Veasna;
- Aggarwal, Neelum T.;
- Alber, Jessica;
- Johnson, Ken;
- Jicha, Gregory A;
- van Dyck, Christopher H;
- Lah, James J.;
- Salloway, Stephen;
- Rafii, Michael S;
- Aisen, Paul S. S;
- Sperling, Reisa A.
Publication type:
Article
Anatomical characterization of pT217‐tau in aged rhesus macaque association cortices: Relevance for trans‐synaptic propagation in sporadic Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075998
By:
- Datta, Dibyadeep;
- Mentone, SueAnn;
- Morozov, Yury;
- van Dyck, Christopher H;
- Arnsten, Amy F. T.
Publication type:
Article
IC‐04‐03: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P8, doi. 10.1016/j.jalz.2018.06.2051
By:
- Mecca, Adam P.;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Godek, Tyler;
- Harris, Joanna;
- Chen, Ming-Kai;
- Nabulsi, Nabeel B.;
- Salardini, Arash;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
Heterogeneity of response to methylphenidate in apathetic patients in the ADMET 2 Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.066932
By:
- Lanctôt, Krista L.;
- Perin, Jamie;
- Vieira, Danielle;
- Rosenberg, Paul B.;
- Herrmann, Nathan;
- Shade, David;
- Lerner, Alan J.;
- Padala, Prasad R;
- Brawman‐Mintzer, Olga;
- van Dyck, Christopher H;
- Porsteinsson, Anton P.;
- Craft, Suzanne;
- Levey, Allan I.;
- Mintzer, Jacobo E
Publication type:
Article
CSF proteomics analysis to investigate the pharmacodynamic response of the S2R modulator CT1812 in Alzheimer's disease patients from the SPARC clinical trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068166
By:
- Pandey, Kiran;
- Waybright, Lora;
- Duong, Duc M.;
- Malagise, Evi;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Mecca, Adam P;
- van Dyck, Christopher H;
- Caggiano, Anthony O;
- Seyfried, Nicholas T.;
- Hamby, Mary E
Publication type:
Article
Assessment of gray matter microstructure and synaptic density in Alzheimer's Disease: a multimodal imaging study with DWI and SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065064
By:
- Salardini, Elaheh;
- Silva‐Rudberg, Jason A;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Ra, Jocelyn;
- Georgelos, Jamie K;
- Morehouse, Mackenzie R;
- Melino, Kaitlyn P;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H;
- Mecca, Adam P
Publication type:
Article
Association of synaptic density and glucose metabolism with cognitive performance in early Alzheimer's disease: a PET imaging study with [11C]UCB‐J and [18F]FDG.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.062595
By:
- O'Dell, Ryan S.;
- Mecca, Adam P;
- Waszak, Julia;
- Sharp, Emily;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Lu, Yihuan;
- Chupak, Anna;
- Cooper, Emma;
- Lam, Jessica;
- Miller, Alyssa;
- Waldner, Emma;
- Weibley, Hannah;
- Zhao, Yize;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F. T.;
- Carson, Richard E.;
- van Dyck, Christopher H
Publication type:
Article
Examining the effects of sex and age on tau PET binding in the absence of beta‐amyloid pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.061090
By:
- Gordon, Brian A.;
- Flores, Shaney;
- Dincer, Aylin;
- Keefe, Sarah J.;
- McKay, Nicole S.;
- Hobbs, Diana A.;
- Wisch, Julie K.;
- Hornbeck, Russ C.;
- Franklin, Erin E.;
- Jack, Clifford R.;
- Koeppe, Robert A.;
- Xiong, Chengjie;
- van Dyck, Christopher H;
- McDade, Eric;
- Klein, Gregory;
- Pariente, Jeremie;
- Bateman, Randall J.;
- Morris, John C.;
- Ances, Beau M;
- Benzinger, Tammie L.S.
Publication type:
Article
Nanoscale imaging of pT217‐tau in aged rhesus macaque: Trans‐synaptic propagation and seeding of tau pathology in entorhinal cortex.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064956
By:
- Datta, Dibyadeep;
- Mentone, SueAnn;
- Morozov, Yury;
- van Dyck, Christopher H;
- Arnsten, Amy F. T.
Publication type:
Article
Assessment of gray matter microstructure and synaptic density in Alzheimer's Disease: a multimodal imaging study with DWI and SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.065162
By:
- Salardini, Elaheh;
- Silva‐Rudberg, Jason A;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Ra, Jocelyn;
- Georgelos, Jamie K;
- Morehouse, Mackenzie R;
- Melino, Kaitlyn P;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H;
- Mecca, Adam P
Publication type:
Article
Examining the effects of age and sex on tau PET binding in the absence of beta‐amyloid pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.063285
By:
- Gordon, Brian A.;
- Flores, Shaney;
- Dincer, Aylin;
- Keefe, Sarah J.;
- McKay, Nicole S.;
- Hobbs, Diana A.;
- Wisch, Julie K.;
- Hornbeck, Russ C.;
- Franklin, Erin E.;
- Jack, Clifford R.;
- Koeppe, Robert A.;
- Xiong, Chengjie;
- McDade, Eric;
- van Dyck, Christopher H;
- Klein, Gregory;
- Pariente, Jeremie;
- Bateman, Randall J.;
- Morris, John C.;
- Perrin, Richard J.;
- Benzinger, Tammie L.S.
Publication type:
Article
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 12, p. 2527, doi. 10.1002/alz.12582
By:
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- Sharp, Emily S.;
- Banks, Emmie R.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Lipior, Sylwia;
- Diepenbrock, Nina G.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Nabulsi, Nabeel B.;
- Vander Wyk, Brent C.;
- Arnsten, Amy F. T.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
EXERT: Impact of COVID‐19 on retention and intervention delivery of a large multisite exercise trial in adults with MCI.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056518
By:
- Baker, Laura D;
- Cotman, Carl W;
- Morrison, Rosemary H;
- Katula, Jeffrey A;
- Chmelo, Elizabeth;
- Hodge, Heather;
- Johnson, Cara;
- Kipperman, Sean A;
- Matthews, Genevieve;
- Bennett, Daniel;
- Mason, Jennifer;
- LaCroix, Andrea Z;
- van Dyck, Christopher H;
- Okonkwo, Ozioma C;
- Tam, Steven P;
- Fairchild, Jennifer Kaci;
- Li, Clara;
- Welsh‐Bohmer, Kathleen A;
- Feldman, Howard
Publication type:
Article
Apathy in Dementia Methylphenidate Trial 2 (ADMET2): Results of a phase III, placebo‐controlled, double‐blind, 6‐month, multi‐center, randomized clinical trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051489
By:
- Mintzer, Jacobo E.;
- Scherer, Roberta;
- Drye, Lea T.;
- Lanctôt, Krista L.;
- Rosenberg, Paul B.;
- Herrmann, Nathan;
- Padala, Prasad R;
- Brawman‐Mintzer, Olga;
- Lerner, Alan J.;
- Levey, Allan I;
- Porsteinsson, Anton P.;
- van Dyck, Christopher H
Publication type:
Article
Synaptic density is associated with cognitive performance in Alzheimer’s disease: A PET imaging study with [11C]UCB‐J.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054213
By:
- van Dyck, Christopher H.;
- Sharp, Emily;
- O'Dell, Ryan S.;
- Banks, Emmie R.;
- Bartlett, Hugh H.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Harris, Joanna E.;
- Ni, Gessica S.;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Wyk, Brent C. Vander;
- Huang, Yiyun;
- Arnsten, Amy F. T.;
- Carson, Richard E.;
- Mecca, Adam P.
Publication type:
Article
Cerebrospinal fluid and brain PET measures of synaptic density glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054831
By:
- Mecca, Adam P.;
- Ashton, Nicholas J.;
- Chen, Ming‐Kai;
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Brinkmalm, Ann;
- Kvartsberg, Hlin;
- Schöll, Michael;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Carson, Richard E.;
- van Dyck, Christopher H.;
- Nilsson, Johanna
Publication type:
Article
Subcellular localization of PDE4D and HCN1 in rhesus macaque entorhinal cortex layer II: Signature of vulnerability in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054671
By:
- Datta, Dibyadeep;
- Mentone, SueAnn;
- Morozov, Yury;
- van Dyck, Christopher H;
- Arnsten, Amy F. T.
Publication type:
Article
[11C]PiB and [18F]AV45 PET radiotracers show different rates of amyloid‐β clearance.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056094
By:
- Chen, Charles D.;
- McCullough, Austin A.;
- Gordon, Brian A.;
- Joseph‐Mathurin, Nelly;
- Wang, Guoqiao;
- Li, Yan;
- Xiong, Chengjie;
- Pontecorvo, Michael J.;
- Klein, Gregory;
- Shcherbinin, Sergey;
- Higgins, Ixavier A.;
- Masters, Colin L;
- Clifford, David B.;
- van Dyck, Christopher H;
- Masellis, Mario;
- Hsiung, Ging‐Yuek Robin;
- Gauthier, Serge;
- Bateman, Randall J.;
- McDade, Eric;
- Salloway, Stephen P.
Publication type:
Article
Recruitment of a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 11, p. 1808, doi. 10.1002/alz.12401
By:
- Shadyab, Aladdin H.;
- LaCroix, Andrea Z.;
- Feldman, Howard H.;
- van Dyck, Christopher H.;
- Okonkwo, Ozioma C.;
- Tam, Steven P.;
- Fairchild, J. Kaci;
- Welsh‐Bohmer, Kathleen A.;
- Matthews, Genevieve;
- Bennett, Daniel;
- Shadyab, Alexandre A.;
- Schafer, Kimberly A.;
- Morrison, Rosemary H.;
- Kipperman, Sean A.;
- Mason, Jennifer;
- Tan, Donna;
- Thomas, Ronald G.;
- Cotman, Carl W.;
- Baker, Laura D.
Publication type:
Article
Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primates.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 920, doi. 10.1002/alz.12325
By:
- Datta, Dibyadeep;
- Leslie, Shannon N.;
- Wang, Min;
- Morozov, Yury M.;
- Yang, Shengtao;
- Mentone, SueAnn;
- Zeiss, Caroline;
- Duque, Alvaro;
- Rakic, Pasko;
- Horvath, Tamas L.;
- Dyck, Christopher H.;
- Nairn, Angus C.;
- Arnsten, Amy F.T.
Publication type:
Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 2, p. 316, doi. 10.1002/alz.12190
By:
- Mecca, Adam P.;
- Dyck, Christopher H.
Publication type:
Article
The calcium‐containing smooth endoplasmic reticulum is a focus of risk factors for early‐ and late‐onset Alzheimer's disease: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047651
By:
- Datta, Dibyadeep;
- Mentone, SueAnn;
- Morozov, Yury;
- van Dyck, Christopher H;
- Arnsten, Amy FT
Publication type:
Article
Validation of a simplified tissue‐to‐reference ratio measurement using SUVR for the assessment of synaptic density alterations in Alzheimer's disease using [11C]UCB‐J PET: Neuroimaging / New imaging methods.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045928
By:
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Young, Juan;
- Dahal, Rabin;
- Singh, Edward;
- Waheed, Aisha;
- Banks, Emmie R.;
- Harris, Joanna E.;
- Chen, Ming‐Kai;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.;
- Mecca, Adam P.
Publication type:
Article
Recruitment for a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial: Prevention (nonpharmacological) / Exercise.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044658
By:
- LaCroix, Andrea Z;
- van Dyck, Christopher H;
- Okonkwo, Ozioma C;
- Tam, Steven P;
- Fairchild, Jennifer Kaci;
- Li, Clara;
- Welsh‐Bohmer, Kathleen A;
- Shadyab, Aladdin H;
- Matthews, Genevieve;
- Bennett, Daniel;
- Shadyab, Alexandre;
- Schafer, Kimberly A;
- Morrison, Rosemary H;
- Kipperman, Sean A;
- Tan, Donna;
- Feldman, Howard H;
- Cotman, Carl W;
- Baker, Laura D
Publication type:
Article
11C‐PBR28 brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer's disease: Neuroimaging / New imaging methods.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043584
By:
- Salardini, Arash;
- Hillmer, Ansel T;
- Mecca, Adam P;
- Hashemi‐Aghdam, Arsalan;
- Laltoo, Emily;
- Savoia, Sarah;
- O'Dell, Ryan S;
- Harris, Joanna E;
- Godek, Tyler A.;
- Nabulsi, Nabeel B;
- Lim, Keunpoong;
- Ropchan, Jim R;
- Huang, Yiyun;
- Cosgrove, Kelly;
- Carson, Richard E;
- Strittmatter, Stephen M;
- van Dyck, Christopher H
Publication type:
Article
Biochemical characterization of age‐related calcium‐cAMP‐PKA signaling dysregulation and its effect on tau pathology in rhesus monkey cortex: Molecular and cell biology/calcium homeostasis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042017
By:
- Leslie, Shannon N.;
- Datta, Dibyadeep;
- Wang, Min;
- van Dyck, Christopher H.;
- Arnsten, Amy F. T.;
- Nairn, Angus C.
Publication type:
Article
ICA‐derived sources of synaptic density PET ([11C]UCB‐J) relate to cognitive impairment severity in Alzheimer's disease: Neuroimaging: Imaging the human synapse in AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041197
By:
- Fang, Xiaotian T.;
- Mecca, Adam P.;
- Naganawa, Mika;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- van Dyck, Christopher H.;
- Carson, Richard E.
Publication type:
Article
PBR28 Brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer's disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037792
By:
- Salardini, Arash;
- Hillmer, Ansel T.;
- Mecca, Adam P.;
- Hashemi‐Aghdam, Arsalan;
- Laltoo, Emily;
- Savoia, Sarah;
- O'Dell, Ryan S.;
- Harris, Joanna E.;
- Godek, Tyler A.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Cosgrove, Kelly;
- Carson, Richard E.;
- Strittmatter, Stephen M;
- van Dyck, Christopher H.
Publication type:
Article
In vivo measurement of widespread synaptic loss and associated tau accumulation in early Alzheimer's disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037791
By:
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Gallezot, Jean‐Dominique;
- Nabulsi, Nabeel B.;
- Ropchan, Jim R.;
- Ye, Yunpeng;
- Wyk, Brent C. Vander;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 974, doi. 10.1002/alz.12097
By:
- Mecca, Adam P.;
- Chen, Ming‐Kai;
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Wyk, Brent C. Vander;
- Varma, Pradeep;
- Arnsten, Amy F. T.;
- Huang, Yiyun;
- Carson, Richard E.;
- Dyck, Christopher H.
Publication type:
Article
P4‐481: ASSOCIATION BETWEEN ENTORHINAL CORTICAL TAU ACCUMULATION AND HIPPOCAMPAL SYNAPTIC DENSITY IN OLDER INDIVIDUALS WITH NORMAL COGNITION AND EARLY ALZHEIMER'S DISEASE: PRELIMINARY EXPERIENCE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1497, doi. 10.1016/j.jalz.2019.08.027
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Gallezot, Jean-Dominique;
- Charil, Arnaud;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F.T.;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
P4‐143: LOSS OF PDE4D REGULATION OF CAMP‐PKA‐CALCIUM SIGNALING IN THE AGING ASSOCIATION CORTEX: INCREASING RISK FOR LOAD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1329, doi. 10.1016/j.jalz.2019.06.3804
By:
- Datta, Dibyadeep;
- Morozov, Yury;
- Arellano, Jon;
- van Dyck, Christopher H.;
- Arnsten, Amy F.T.
Publication type:
Article
P2‐349: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY OF HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P729, doi. 10.1016/j.jalz.2019.06.2756
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐P‐140: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY IN HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4254
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐P‐140: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY IN HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4254
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
P4‐321: TAU PET IN A4: PRELIMINARY REPORT.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1583, doi. 10.1016/j.jalz.2018.07.144
By:
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Raman, Rema;
- Donohue, Michael C.;
- Sun, Chung-Kai;
- Jacobs, Heidi IL.;
- Marek, Kenneth;
- Seibyl, John;
- Mintun, Mark A.;
- Shcherbinin, Sergey;
- Pontecorvo, Michael J.;
- Mormino, Beth C.;
- Rowe, Christopher C.;
- van Dyck, Christopher H.;
- Salloway, Stephen;
- Jack, Clifford R.;
- Yaari, Roy;
- Holdridge, Karen C.;
- Aisen, Paul S.;
- Sperling, Reisa A.
Publication type:
Article
P4‐013: DESIGN OF A PHASE‐3 TRIAL (APECS) TO EVALUATE THE BACE INHIBITOR VERUBECESTAT IN PRODROMAL AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1436, doi. 10.1016/j.jalz.2018.06.2415
By:
- Egan, Mike F.;
- Voss, Tiffini;
- Kost, James;
- Tariot, Pierre N.;
- Aisen, Paul S.;
- Cummings, Jeffrey L.;
- Vellas, Bruno;
- van Dyck, Christopher H.;
- Sur, Cyrille;
- Mukai, Yuki;
- Furtek, Christine;
- Mahoney, Erin M.;
- Mozley, Lyn Harper;
- Mo, Yi;
- Michelson, David
Publication type:
Article

Found: 119