Found: 21
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Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System.
- Published in:
- Journal of Oncology, 2019, p. 1, doi. 10.1155/2019/5245034
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- Publication type:
- Article
A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.
- Published in:
- BMC Immunology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2172-15-18
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- Article
The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
- Published in:
- Scientific Reports, 2017, p. 41643, doi. 10.1038/srep41643
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- Article
Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140585
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- Article
Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation <i>In Vivo</i>.
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- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095893
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- Article
Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma.
- Published in:
- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010849
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- Article
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
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- Cancers, 2020, v. 12, n. 9, p. 2576, doi. 10.3390/cancers12092576
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- Article
PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron.
- Published in:
- Clinical & Translational Medicine, 2022, v. 12, n. 4, p. 1, doi. 10.1002/ctm2.806
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- Publication type:
- Article
Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.766888
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- Publication type:
- Article
Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.
- Published in:
- PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0214901
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- Publication type:
- Article
LC–MS/MS method for the quantitation of a dual PI3K/BRD4 inhibitor SF2523 in mouse plasma: Application to plasma protein binding and metabolism studies.
- Published in:
- Biomedical Chromatography, 2023, v. 37, n. 8, p. 1, doi. 10.1002/bmc.5643
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- Publication type:
- Article
In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 4, p. 697, doi. 10.1007/s00280-009-1075-9
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- Article
Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68964-6
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- Article
PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
- Published in:
- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150836
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- Publication type:
- Article
Vascular remodeling underlies rebleeding in hemophilic arthropathy.
- Published in:
- American Journal of Hematology, 2015, v. 90, n. 11, p. 1027, doi. 10.1002/ajh.24133
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- Article
Glutaminase-free asparaginase from vibrio succinogenes: An antilymphoma enzyme lacking hepatotoxicity.
- Published in:
- International Journal of Cancer, 1982, v. 30, n. 3, p. 343, doi. 10.1002/ijc.2910300314
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- Publication type:
- Article
Characterization of the effects of asparaginase from escherichia coli and a glutaminase-free asparaginase from vibrio succinogenes on specific cell-mediated cytotoxicity.
- Published in:
- International Journal of Cancer, 1981, v. 27, n. 1, p. 59, doi. 10.1002/ijc.2910270110
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- Article
Mouse mammary tumor virus (MMTV) antigen(s) are present on B lymphocytes of BALB/c mice.
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- International Journal of Cancer, 1979, v. 24, n. 6, p. 813, doi. 10.1002/ijc.2910240620
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- Article
COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges.
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- Theranostics, 2021, v. 11, n. 2, p. 731, doi. 10.7150/thno.51471
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- Article
A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.
- Published in:
- 2020
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- Publication type:
- Letter
Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.
- Published in:
- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182851
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- Article