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The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809316
By:
- Neumann, Ulf;
- Ufer, Mike;
- Jacobson, Laura H;
- Rouzade‐Dominguez, Marie‐Laure;
- Huledal, Gunilla;
- Kolly, Carine;
- Lüönd, Rainer M;
- Machauer, Rainer;
- Veenstra, Siem J;
- Hurth, Konstanze;
- Rueeger, Heinrich;
- Tintelnot‐Blomley, Marina;
- Staufenbiel, Matthias;
- Shimshek, Derya R;
- Perrot, Ludovic;
- Frieauff, Wilfried;
- Dubost, Valerie;
- Schiller, Hilmar;
- Vogg, Barbara;
- Beltz, Karen
Publication type:
Article
FTS3‐01‐01: UMIBECESTAT (CNP520) IS NOT ASSOCIATED WITH CHANGES IN HIPPOCAMPAL MORPHOLOGY IN RATS OR CHANGES IN CSF AD BIOMARKERS IN HUMANS TREATED FOR 3 MONTHS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P872, doi. 10.1016/j.jalz.2019.06.4618
By:
- Graf, Ana;
- Kolly, Carine;
- Dubost, Valerie;
- Vassar, Robert J.;
- Portelius, Erik;
- Höglund, Kina;
- Blennow, Kaj;
- Rouzade-Dominguez, Marie-Laure;
- Pezous, Nicole;
- Kretz, Sandrine;
- Vormfelde, Stefan Viktor;
- Neumann, Ulf
Publication type:
Article
PRECLINICAL PHARMACOLOGY OF BACE INHIBITOR CNP520.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P433, doi. 10.1016/j.jalz.2016.06.831
By:
- Neumann, Ulf;
- Jacobson, Laura Helen;
- Perrot, Ludovik;
- Beltz, Karen;
- Vogg, Barbara;
- Brzak, Irena;
- Tanja, Dittmar;
- Trappe, Vera;
- Kolly, Carine;
- Frieauff, Wilfried;
- Dubost, Valerie;
- Jivkov, Magali Natacha;
- Theil, Diethilde;
- Staufenbiel, Matthias;
- Shimshek, Derya Robert
Publication type:
Article
Unaltered hepatic wound healing response in male rats with ancestral liver injury.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41998-w
By:
- Beil, Johanna;
- Perner, Juliane;
- Pfaller, Lena;
- Gérard, Marie-Apolline;
- Piaia, Alessandro;
- Doelemeyer, Arno;
- Wasserkrug Naor, Adi;
- Martin, Lori;
- Piequet, Aline;
- Dubost, Valérie;
- Chibout, Salah-Dine;
- Moggs, Jonathan;
- Terranova, Rémi
Publication type:
Article
Unaltered hepatic wound healing response in male rats with ancestral liver injury.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41998-w
By:
- Beil, Johanna;
- Perner, Juliane;
- Pfaller, Lena;
- Gérard, Marie-Apolline;
- Piaia, Alessandro;
- Doelemeyer, Arno;
- Wasserkrug Naor, Adi;
- Martin, Lori;
- Piequet, Aline;
- Dubost, Valérie;
- Chibout, Salah-Dine;
- Moggs, Jonathan;
- Terranova, Rémi
Publication type:
Article
Heart Structure-Specific Transcriptomic Atlas Reveals Conserved microRNA-mRNA Interactions.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052442
By:
- Vacchi-Suzzi, Caterina;
- Hahne, Florian;
- Scheubel, Philippe;
- Marcellin, Magali;
- Dubost, Valerie;
- Westphal, Magdalena;
- Boeglen, Catherine;
- Büchmann-Møller, Stine;
- Cheung, Ming Sin;
- Cordier, André;
- De Benedetto, Christopher;
- Deurinck, Mark;
- Frei, Moritz;
- Moulin, Pierre;
- Oakeley, Edward;
- Grenet, Olivier;
- Grevot, Armelle;
- Stull, Robert;
- Theil, Diethilde;
- Moggs, Jonathan G.
Publication type:
Article
Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01340
By:
- Theil, Diethilde;
- Smith, Paul;
- Huck, Catherine;
- Gilbart, Yoann;
- Kakarieka, Algirdas;
- Leppert, David;
- Rauld, Celine;
- Schmid, Cindy;
- Baumgartner, Reto;
- Stuber, Nathalie;
- Cordoba, Francisco;
- Dubost, Valerie;
- Darribat, Katy;
- Jivkov, Magali;
- Frieauff, Wilfried;
- Kneuer, Rainer;
- Stoeckli, Markus;
- Reinker, Stefan;
- Mansfield, Keith;
- Carballido, José M.
Publication type:
Article
Biomarker-Based Classification and Localization of Renal Lesions Using Learned Representations of Histology—A Machine Learning Approach to Histopathology.
Published in:
Toxicologic Pathology, 2021, v. 49, n. 4, p. 798, doi. 10.1177/0192623320987202
By:
- Freyre, Christophe A. C.;
- Spiegel, Stephan;
- Gubser Keller, Caroline;
- Vandemeulebroecke, Marc;
- Hoefling, Holger;
- Dubost, Valerie;
- Cörek, Emre;
- Moulin, Pierre;
- Hossain, Imtiaz
Publication type:
Article
Differential expression of dipeptidyl peptidase IV in human versus cynomolgus monkey skin eccrine sweat glands.
Published in:
Journal of Molecular Histology, 2013, v. 44, n. 6, p. 733, doi. 10.1007/s10735-013-9524-5
By:
- Pantano, Serafino;
- Dubost, Valérie;
- Darribat, Katy;
- Couttet, Philippe;
- Grenet, Olivier;
- Busch, Steven;
- Moulin, Pierre
Publication type:
Article
Molecular characterization of chronic cutaneous wounds reveals subregion‐ and wound type‐specific differential gene expression.
Published in:
International Wound Journal, 2024, v. 21, n. 4, p. 1, doi. 10.1111/iwj.14447
By:
- Richards, Shola Michelle;
- Gubser Keller, Caroline;
- Kreutzer, Robert;
- Greiner, Géraldine;
- Ley, Svenja;
- Doelemeyer, Arno;
- Dubost, Valerie;
- Flandre, Thierry;
- Kirkland, Susan;
- Carbone, Walter;
- Pandya, Rishika;
- Knehr, Judith;
- Roma, Guglielmo;
- Schuierer, Sven;
- Bouchez, Laure;
- Seuwen, Klaus;
- Aebi, Alexandra;
- Westhead, David;
- Hintzen, Gabriele;
- Jurisic, Giorgia
Publication type:
Article
Vascular Origin of Vildagliptin-induced Skin Effects in Cynomolgus Monkeys: Pathomechanistic Role of Peripheral Sympathetic System and Neuropeptide Y.
Published in:
Toxicologic Pathology, 2014, v. 42, n. 4, p. 684, doi. 10.1177/0192623313516828
By:
- Hoffmann, Peter;
- Bentley, Phil;
- Sahota, Pritam;
- Schoenfeld, Heidi;
- Martin, Lori;
- Longo, Linda;
- Spaet, Robert;
- Moulin, Pierre;
- Pantano, Serafino;
- Dubost, Valerie;
- Lapadula, Dan;
- Burkey, Bryan;
- Kaushik, Virendar;
- Zhou, Wei;
- Hayes, Michael;
- Flavahan, Nick;
- Chibout, Salah-Dine;
- Busch, Steve
Publication type:
Article
Xenobiotic CAR Activators Induce Dlk1-Dio3 Locus Noncoding RNA Expression in Mouse Liver.
Published in:
Toxicological Sciences, 2017, v. 158, n. 2, p. 367, doi. 10.1093/toxsci/kfx104
By:
- Pouché, Lucie;
- Vitobello, Antonio;
- Römer, Michael;
- Glogovac, Milica;
- MacLeod, A. Kenneth;
- Ellinger-Ziegelbauer, Heidrun;
- Westphal, Magdalena;
- Dubost, Valérie;
- Stiehl, Daniel Philipp;
- Dumotier, Bérengère;
- Fekete, Alexander;
- Moulin, Pierre;
- Zell, Andreas;
- Schwarz, Michael;
- Moreno, Rita;
- Huang, Jeffrey T. J.;
- Elcombe, Cliff R.;
- Henderson, Colin J.;
- Wolf, C. Roland;
- Moggs, Jonathan G.
Publication type:
Article
Comparative Renal Safety Assessment of the Hepatitis B Drugs, Adefovir, Tenofovir, Telbivudine and Entecavir in Rats.
Published in:
Toxicological Sciences, 2017, v. 155, n. 1, p. 283, doi. 10.1093/toxsci/kfw208
By:
- Uteng, Marianne;
- Mahl, Andreas;
- Beckmann, Nicolau;
- Piaia, Alessandro;
- Ledieu, David;
- Dubost, Valerie;
- Tritto, Elaine;
- Wolf, Armin;
- Moulin, Pierre;
- Li Li;
- Chibout, Salah-Dine;
- Pognan, Francois
Publication type:
Article
Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors.
Published in:
Toxicological Sciences, 2014, v. 139, n. 2, p. 501, doi. 10.1093/toxsci/kfu038
By:
- Luisier, Raphaëlle;
- Lempiäinen, Harri;
- Scherbichler, Nina;
- Braeuning, Albert;
- Geissler, Miriam;
- Dubost, Valerie;
- Müller, Arne;
- Scheer, Nico;
- Chibout, Salah-Dine;
- Hara, Hisanori;
- Picard, Frank;
- Theil, Diethilde;
- Couttet, Philippe;
- Vitobello, Antonio;
- Grenet, Olivier;
- Grasl-Kraupp, Bettina;
- Ellinger-Ziegelbauer, Heidrun;
- Thomson, John P.;
- Meehan, Richard R.;
- Elcombe, Clifford R.
Publication type:
Article
Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion.
Published in:
Toxicological Sciences, 2013, v. 131, n. 2, p. 375
By:
- Lempiäinen, Harri;
- Couttet, Philippe;
- Bolognani, Federico;
- Müller, Arne;
- Dubost, Valérie;
- Luisier, Raphaëlle;
- Del Rio Espinola, Alberto;
- Vitry, Veronique;
- Unterberger, Elif B.;
- Thomson, John P.;
- Treindl, Fridolin;
- Metzger, Ute;
- Wrzodek, Clemens;
- Hahne, Florian;
- Zollinger, Tulipan;
- Brasa, Sarah;
- Kalteis, Magdalena;
- Marcellin, Magali;
- Giudicelli, Fanny;
- Braeuning, Albert
Publication type:
Article

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