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A qPCR to quantify Wolbachia from few Onchocerca volvulus microfilariae as a surrogate for adult worm histology in clinical trials of antiwolbachial drugs.
Published in:
Parasitology Research, 2022, v. 121, n. 4, p. 1199, doi. 10.1007/s00436-021-07411-5
By:
- Schlabe, Stefan;
- Korir, Patricia;
- Lämmer, Christine;
- Landmann, Frederic;
- Dubben, Bettina;
- Koschel, Marianne;
- Albers, Anna;
- Debrah, Linda Batsa;
- Debrah, Alexander Yaw;
- Hübner, Marc P.;
- Pfarr, Kenneth;
- Klarmann-Schulz, Ute;
- Hoerauf, Achim
Publication type:
Article
Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 1, p. 1, doi. 10.1371/journal.pntd.0005156
By:
- Ricchiuto, Arcangelo;
- Arriens, Sandra;
- Dubben, Bettina;
- Klarmann-Schulz, Ute;
- Hoerauf, Achim;
- Specht, Sabine;
- Fimmers, Rolf;
- Batsa, Linda;
- Osei-Mensah, Jubin;
- Mubarik, Yusif;
- Debrah, Alexander Yaw;
- Ayisi-Boateng, Nana Kwame;
- Konadu, Peter;
- Ford, Louise;
- Taylor, Mark
Publication type:
Article
Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds.
Published in:
PLoS Neglected Tropical Diseases, 2019, v. 13, n. 1, p. 1, doi. 10.1371/journal.pntd.0006320
By:
- Hübner, Marc P.;
- Ehrens, Alexandra;
- Koschel, Marianne;
- Dubben, Bettina;
- Lenz, Franziska;
- Frohberger, Stefan J.;
- Specht, Sabine;
- Hoerauf, Achim;
- Quirynen, Ludo;
- Lachau-Durand, Sophie;
- Tekle, Fetene;
- Baeten, Benny;
- Engelen, Marc;
- Mackenzie, Charles D.
Publication type:
Article
Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.
Published in:
PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008427
By:
- Hübner, Marc P.;
- Martin, Coralie;
- Specht, Sabine;
- Koschel, Marianne;
- Dubben, Bettina;
- Frohberger, Stefan J.;
- Ehrens, Alexandra;
- Fendler, Martina;
- Struever, Dominique;
- Mitre, Edward;
- Vallarino-Lhermitte, Nathaly;
- Gokool, Suzanne;
- Lustigman, Sara;
- Schneider, Manfred;
- Townson, Simon;
- Hoerauf, Achim;
- Scandale, Ivan
Publication type:
Article
Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.
Published in:
Science Translational Medicine, 2019, v. 11, n. 491, p. N.PAG, doi. 10.1126/scitranslmed.aav3523
By:
- Bakowski, Malina A.;
- Shiroodi, Roohollah Kazem;
- Liu, Renhe;
- Olejniczak, Jason;
- Yang, Baiyuan;
- Gagaring, Kerstin;
- Guo, Hui;
- White, Pamela M.;
- Chappell, Laura;
- Debec, Alain;
- Landmann, Frédéric;
- Dubben, Bettina;
- Lenz, Franziska;
- Struever, Dominique;
- Ehrens, Alexandra;
- Frohberger, Stefan J.;
- Sjoberg, Hanna;
- Pionnier, Nicolas;
- Murphy, Emma;
- Archer, John
Publication type:
Article
Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial.
Published in:
Clinical Infectious Diseases, 2015, v. 61, n. 4, p. 517, doi. 10.1093/cid/civ363
By:
- Debrah, Alexander Yaw;
- Specht, Sabine;
- Klarmann-Schulz, Ute;
- Batsa, Linda;
- Mand, Sabine;
- Marfo-Debrekyei, Yeboah;
- Fimmers, Rolf;
- Dubben, Bettina;
- Kwarteng, Alexander;
- Osei-Atweneboana, Mike;
- Boakye, Daniel;
- Ricchiuto, Arcangelo;
- Büttner, Marcelle;
- Adjei, Ohene;
- Mackenzie, Charles D.;
- Hoerauf, Achim
Publication type:
Article
Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis.
Published in:
PLoS Neglected Tropical Diseases, 2012, v. 6, n. 3, p. 1, doi. 10.1371/journal.pntd.0001558
By:
- Ziewer, Sebastian;
- Hübner, Marc P.;
- Dubben, Bettina;
- Hoffmann, Wolfgang H.;
- Bain, Odile;
- Martin, Coralie;
- Hoerauf, Achim;
- Specht, Sabine
Publication type:
Article
Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis.
Published in:
PLoS Neglected Tropical Diseases, 2012, v. 6, n. 3, p. 1, doi. 10.1371/journal.pntd.0001558
By:
- Ziewer, Sebastian;
- Hübner, Marc P.;
- Dubben, Bettina;
- Hoffmann, Wolfgang H.;
- Bain, Odile;
- Martin, Coralie;
- Hoerauf, Achim;
- Specht, Sabine
Publication type:
Article
A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis.
Published in:
PLoS Neglected Tropical Diseases, 2023, v. 16, n. 5, p. 1, doi. 10.1371/journal.pntd.0011365
By:
- Opoku, Nicholas O.;
- Doe, Felix;
- Dubben, Bettina;
- Fetcho, Nicole;
- Fischer, Kerstin;
- Fischer, Peter U.;
- Gordor, Shelter;
- Goss, Charles W.;
- Gyasi, Michael E.;
- Hoerauf, Achim;
- Hong, Augustine R.;
- Kanza, Eric;
- King, Christopher L.;
- Laryea, Ruth;
- Lew, Daphne;
- Seidu, Mahmood A.;
- Weil, Gary J.
Publication type:
Article

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