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Shared acquired genomic changes in zebrafish and human T-ALL.
Published in:
Oncogene, 2011, v. 30, n. 41, p. 4289, doi. 10.1038/onc.2011.138
By:
- Rudner, L A;
- Brown, K H;
- Dobrinski, K P;
- Bradley, D F;
- Garcia, M I;
- Smith, A C H;
- Downie, J M;
- Meeker, N D;
- Look, A T;
- Downing, J R;
- Gutierrez, A;
- Mullighan, C G;
- Schiffman, J D;
- Lee, C;
- Trede, N S;
- Frazer, J K
Publication type:
Article
Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11.
Published in:
Oncogene, 2007, v. 26, n. 39, p. 5816, doi. 10.1038/sj.onc.1210361
By:
- Flotho, C.;
- Steinemann, D.;
- Mullighan, C. G.;
- Neale, G.;
- Mayer, K.;
- Kratz, C. P.;
- Schlegelberger, B.;
- Downing, J. R.;
- Niemeyer, C. M.
Publication type:
Article
The role of the AML1 transcription factor in leukemogenesis.
Published in:
2001
By:
- Lorsbach, R B;
- Downing, J R
Publication type:
journal article
Erratum: Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells.
Published in:
2003
By:
- Cheok, M H;
- Yang, W;
- Pui, C-H;
- Downing, J R;
- Cheng, C;
- Naeve, C W;
- Relling, M V;
- Evans, W E
Publication type:
Correction Notice
AML1/CBFbeta transcription complex: its role in normal hematopoiesis and leukemia.
Published in:
2001
By:
- Downing, J R
Publication type:
journal article
Multicolor spectral karyotyping identifies novel translocations in childhood acute lymphoblastic leukemia.
Published in:
2001
By:
- Mathew, S;
- Rao, P H;
- Dalton, J;
- Downing, J R;
- Raimondi, S C
Publication type:
journal article
Significance of the TEL-AML fusion gene in childhood AML.
Published in:
1999
By:
- Rubnitz, J E;
- Downing, J R;
- Pui, C-H
Publication type:
Letter
Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup.
Published in:
1999
By:
- Rubnitz, J E;
- Behm, F G;
- Wichlan, D;
- Ryan, C;
- Sandlund, J T;
- Ribeiro, R C;
- Rivera, G K;
- Hancock, M L;
- Relling, M V;
- Evans, W E;
- Pui, C-H;
- Downing, J R
Publication type:
journal article
The role of TEL fusion genes in pediatric leukemias.
Published in:
1999
By:
- Rubnitz, J E;
- Pui, C-H;
- Downing, J R
Publication type:
journal article
A multiplex RT-PCR assay for the detection of chimeric transcripts encoded by the risk-stratifying translocations of pediatric acute lymphoblastic leukemia.
Published in:
1998
By:
- Scurto, P;
- Rocha, M Hsu;
- Kane, J R;
- Williams, W K;
- Haney, D M;
- Conn, W P;
- Shurtleff, S A;
- Downing, J R;
- Hsu Rocha, M
Publication type:
journal article
Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII.
Published in:
1997
By:
- Rubnitz, J E;
- Behm, F G;
- Pui, C-H;
- Evans, W E;
- Relling, M V;
- Raimondi, S C;
- Harrison, P L;
- Sandlund, J T;
- Ribeiro, R C;
- Grosveld, G;
- Downing, J R
Publication type:
journal article
The use of critical loads in emission reduction agreements in Europe
Published in:
Water, Air & Soil Pollution, 1995, v. 85, n. 4, p. 2381
By:
- Posch, M.;
- Hettelingh, J.-P.;
- Downing, R. J.;
- De Smet, P. A. M.
Publication type:
Article
A revised definition for cure of childhood acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 12, p. 2336, doi. 10.1038/leu.2014.142
By:
- Pui, C H;
- Pei, D;
- Campana, D;
- Cheng, C;
- Sandlund, J T;
- Bowman, W P;
- Hudson, M M;
- Ribeiro, R C;
- Raimondi, S C;
- Jeha, S;
- Howard, S C;
- Bhojwani, D;
- Inaba, H;
- Rubnitz, J E;
- Metzger, M L;
- Gruber, T A;
- Coustan-Smith, E;
- Downing, J R;
- Leung, W H;
- Relling, M V
Publication type:
Article
IDH1 and IDH2 mutations in pediatric acute leukemia.
Published in:
2011
By:
- Andersson, A K;
- Miller, D W;
- Lynch, J A;
- Lemoff, A S;
- Cai, Z;
- Pounds, S B;
- Radtke, I;
- Yan, B;
- Schuetz, J D;
- Rubnitz, J E;
- Ribeiro, R C;
- Raimondi, S C;
- Zhang, J;
- Mullighan, C G;
- Shurtleff, S A;
- Schulman, B A;
- Downing, J R
Publication type:
journal article
Impact of genetic variation in FKBP5 on clinical response in pediatric acute myeloid leukemia patients: a pilot study.
Published in:
2011
By:
- Mitra, A. K.;
- Crews, K.;
- Pounds, S.;
- Cao, X.;
- Downing, J. R.;
- Raimondi, S.;
- Campana, D.;
- Ribeiro, R. C.;
- Rubnitz, J. E.;
- Lamba, J. K.
Publication type:
Letter
Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia.
Published in:
2010
By:
- Pui, C. H.;
- Pei, D.;
- Sandlund, J. T.;
- Ribeiro, R. C.;
- Rubnitz, J. E.;
- Raimondi, S. C.;
- Onciu, M.;
- Campana, D.;
- Kun, L. E.;
- Jeha, S.;
- Cheng, C.;
- Howard, S. C.;
- Metzger, M. L.;
- Bhojwani, D.;
- Downing, J. R.;
- Evans, W. E.;
- Relling, M. V.
Publication type:
journal article
Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis.
Published in:
Leukemia (08876924), 2010, v. 24, n. 2, p. 438, doi. 10.1038/leu.2009.263
By:
- Bullinger, L.;
- Krönke, J.;
- Schön, C.;
- Radtke, I.;
- Urlbauer, K.;
- Botzenhardt, U.;
- Gaidzik, V.;
- Carió, A.;
- Senger, C.;
- Schlenk, R. F.;
- Downing, J. R.;
- Holzmann, K.;
- Döhner, K.;
- Döhner, H.
Publication type:
Article
Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial.
Published in:
2009
By:
- Rubnitz, J. E.;
- Crews, K. R.;
- Pounds, S.;
- Yang, S.;
- Campana, D.;
- Gandhi, V. V.;
- Raimondi, S. C.;
- Downing, J. R.;
- Razzouk, B. I.;
- Pui, C.-H.;
- Ribeiro, R. C.
Publication type:
journal article
Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1.
Published in:
2009
By:
- Jeha, S.;
- Pei, D.;
- Raimondi, S. C.;
- Onciu, M.;
- Campana, D.;
- Cheng, C.;
- Sandlund, J. T.;
- Ribeiro, R. C.;
- Rubnitz, J. E.;
- Howard, S. C.;
- Downing, J. R.;
- Evans, W. E.;
- Relling, M. V.;
- Pui, C.-H.
Publication type:
journal article
Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions.
Published in:
Leukemia (08876924), 2009, v. 23, n. 7, p. 1209, doi. 10.1038/leu.2009.18
By:
- Mullighan, C. G.;
- Downing, J. R.
Publication type:
Article
Coding polymorphisms in CD33 and response to gemtuzumab ozogamicin in pediatric patients with AML: a pilot study.
Published in:
2009
By:
- Lamba, J. K.;
- Pounds, S.;
- Cao, X.;
- Downing, J. R.;
- Campana, D.;
- Ribeiro, R. C.;
- Pui, C.-H.;
- Rubnitz, J. E.
Publication type:
Letter
Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias.
Published in:
2007
By:
- Mullighan, C. G.;
- Kennedy, A.;
- Zhou, X.;
- Radtke, I.;
- Phillips, L. A.;
- Shurtleff, S. A.;
- Downing, J. R.
Publication type:
journal article
MN1 overexpression is an important step in the development of inv(16) AML.
Published in:
Leukemia (08876924), 2007, v. 21, n. 8, p. 1679, doi. 10.1038/sj.leu.2404778
By:
- Carella, C.;
- Bonten, J.;
- Sirma, S.;
- Kranenburg, T. A.;
- Terranova, S.;
- Klein-Geltink, R.;
- Shurtleff, S.;
- Downing, J. R.;
- Zwarthoff, E. C.;
- Liu, P. P.;
- Grosveld, G. C.
Publication type:
Article
Genome-wide approach to identify risk factors for therapy-related myeloid leukemia.
Published in:
Leukemia (08876924), 2006, v. 20, n. 2, p. 239, doi. 10.1038/sj.leu.2404059
By:
- Bogni, A.;
- Cheng, C.;
- Liu, W.;
- Yang, W.;
- Pfeffer, J.;
- Mukatira, S.;
- French, D.;
- Downing, J. R.;
- Pui, C-H;
- Relling, M. V.
Publication type:
Article
Expression of the adaptor protein BLNK/SLP-65 in childhood acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2004, v. 18, n. 5, p. 922, doi. 10.1038/sj.leu.2403349
By:
- Imai, C.;
- Ross, M. E.;
- Reid, G.;
- Coustan-Smith, E.;
- Schultz, K. R.;
- Pui, C. H.;
- Downing, J. R.;
- Campana, D.
Publication type:
Article
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).
Published in:
2003
By:
- Lorsbach, R B;
- Moore, J;
- Mathew, S;
- Raimondi, S C;
- Mukatira, S T;
- Downing, J R
Publication type:
Case Study

Found: 26