Found: 11
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Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00150-8
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- Publication type:
- Article
ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases.
- Published in:
- Science Signaling, 2016, v. 9, n. 415, p. 1, doi. 10.1126/scisignal.aac4374
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- Publication type:
- Article
Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0346-9
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- Publication type:
- Article
Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075414
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- Publication type:
- Article
The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059380
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- Publication type:
- Article
A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutatedp53.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.70429
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- Publication type:
- Article
Flexible Micro Spring Array Device for High-Throughput Enrichment of Viable Circulating Tumor Cells.
- Published in:
- Clinical Chemistry, 2014, v. 60, n. 2, p. 323, doi. 10.1373/clinchem.2013.206805
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- Publication type:
- Article
Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects.
- Published in:
- Science Translational Medicine, 2013, v. 5, n. 171, p. 1, doi. 10.1126/scitranslmed.3004828
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- Publication type:
- Article
Off-Target Lapatinib Activity Sensitizes Colon Cancer Cells Through TRAIL Death Receptor Up-Regulation.
- Published in:
- Science Translational Medicine, 2011, v. 3, n. 86, p. 1, doi. 10.1126/scitranslmed.3001384
- By:
- Publication type:
- Article
Detection of circulating tumor cells in the cerebrospinal fluid of a patient with a solitary metastasis from breast cancer: A case report.
- Published in:
- 2014
- By:
- Publication type:
- Case Study