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Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions.
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- EMBO Reports, 2010, v. 11, n. 9, p. 698, doi. 10.1038/embor.2010.112
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- Article
The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin.
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- Life (2075-1729), 2021, v. 11, n. 4, p. 267, doi. 10.3390/life11040267
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- Article
FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells.
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- Nucleic Acids Research, 2018, v. 46, n. 3, p. 1280, doi. 10.1093/nar/gkx1260
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- Article
Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.
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- Nucleic Acids Research, 2014, v. 42, n. 21, p. 13194, doi. 10.1093/nar/gku1101
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- Article
Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.
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- Nucleic Acids Research, 2013, v. 41, n. 17, p. 8210, doi. 10.1093/nar/gkt566
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- Article
Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone.
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- Nucleic Acids Research, 2011, v. 39, n. 8, p. 3141, doi. 10.1093/nar/gkq1276
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- Article
In vivo reduction of RAD51‐mediated homologous recombination triggers aging but impairs oncogenesis.
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- EMBO Journal, 2023, v. 42, n. 20, p. 1, doi. 10.15252/embj.2022110844
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- Article
Molecular profiling of common fragile sites in human fibroblasts.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1421, doi. 10.1038/nsmb.2155
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- Article
A journey with common fragile sites: From S phase to telophase.
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- Genes, Chromosomes & Cancer, 2019, v. 58, n. 5, p. 305, doi. 10.1002/gcc.22704
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- Article
Relationships Linking Amplification Level to Gene Over-Expression in Gliomas.
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- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014249
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- Article
Matrix attachment regions and transcription units in a polygenic mammalian locus overlapping two isochores.
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- Journal of Cellular Biochemistry, 1997, v. 67, n. 4, p. 541, doi. 10.1002/(SICI)1097-4644(19971215)67:4<541::AID-JCB11>3.0.CO;2-C
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- Article
Characterization of a conserved aphidicolin-sensitive common fragile site at human 4q22 and mouse 6C1: possible association with an inherited disease and cancer.
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- Oncogene, 2004, v. 23, n. 41, p. 6872, doi. 10.1038/sj.onc.1207809
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- Article
Induction of multiple double-strand breaks within an hsr by meganuclease I-SceI expression or fragile site activation leads to formation of double minutes and other chromosomal rearrangements.
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- Oncogene, 2002, v. 21, n. 50, p. 7671, doi. 10.1038/sj.onc.1205880
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- Article
Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13674-5
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- Article
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.
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- Nature, 2011, v. 470, n. 7332, p. 120, doi. 10.1038/nature09745
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- Article
Replication fork movement sets chromatin loop size and origin choice in mammalian cells.
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- Nature, 2008, v. 455, n. 7212, p. 557, doi. 10.1038/nature07233
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- Article
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.
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- Nature Cell Biology, 2013, v. 15, n. 8, p. 1008, doi. 10.1038/ncb2793
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- Article
Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility.
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- Nucleic Acids Research, 2000, v. 28, n. 23, p. 4805, doi. 10.1093/nar/28.23.4805
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- Article
Initiation of DNA replication at the Chinese hamster origin oriGNAI3 relies on local sequences and/or chromatin structures, but not on transcriptionof the nearby GNAI3 gene.
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- Nucleic Acids Research, 1999, v. 27, n. 7, p. 1600, doi. 10.1093/nar/27.7.1600
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- Article
oriGNAI3: a narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques.
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- Nucleic Acids Research, 1998, v. 26, n. 10, p. 2313, doi. 10.1093/nar/26.10.2313
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- Article
Updating the mechanisms of common fragile site instability: how to reconcile the different views?
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- Cellular & Molecular Life Sciences, 2014, v. 71, n. 23, p. 4489, doi. 10.1007/s00018-014-1720-2
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- Article
Wee 1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease.
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- Journal of Cell Biology, 2011, v. 194, n. 4, p. 567
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- Article
Innovative Tools for DNA Topology Probing in Human Cells Reveal a Build-Up of Positive Supercoils Following Replication Stress at Telomeres and at the FRA3B Fragile Site.
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- Cells (2073-4409), 2024, v. 13, n. 16, p. 1361, doi. 10.3390/cells13161361
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- Article
Stepwise Activation of the ATR Signaling Pathway upon Increasing Replication Stress Impacts Fragile Site Integrity.
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- PLoS Genetics, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pgen.1003643
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- Article
Extrachromosomal amplification mechanisms in a glioma with amplified sequences from multiple chromosome loci.
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- Human Molecular Genetics, 2010, v. 19, n. 7, p. 1276, doi. 10.1093/hmg/ddq004
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- Article
Initiation of the breakage–fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I.
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- Human Molecular Genetics, 2002, v. 11, n. 23, p. 2887, doi. 10.1093/hmg/11.23.2887
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- Article
PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching.
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- PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213383
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- Article
Firing of Replication Origins Is Disturbed by a CDK4/6 Inhibitor in a pRb-Independent Manner.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10629, doi. 10.3390/ijms241310629
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USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication.
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- Molecular Oncology, 2016, v. 10, n. 8, p. 1196, doi. 10.1016/j.molonc.2016.05.008
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- Article
TIPIN depletion leads to apoptosis in breast cancer cells.
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- Molecular Oncology, 2015, v. 9, n. 8, p. 1580, doi. 10.1016/j.molonc.2015.04.010
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- Article
Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress.
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- PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006007
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- Article