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Volunteer Challenge With Enterotoxigenic Escherichia coli That Express Intestinal Colonization Factor Fimbriae CS17 and CS19.
Published in:
Journal of Infectious Diseases, 2011, v. 204, n. 1, p. 60, doi. 10.1093/infdis/jir220
By:
- McKenzie, Robin;
- Porter, Chad K.;
- Cantrell, Joyce A.;
- DeNearing, Barbara;
- O’Dowd, Aisling;
- Grahek, Shannon L.;
- Sincock, Stephanie A.;
- Woods, Colleen;
- Sebeny, Peter;
- Sack, David A.;
- Tribble, David R.;
- Bourgeois, A. Louis;
- Savarino, Stephen J.
Publication type:
Article
Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers.
Published in:
PLoS Neglected Tropical Diseases, 2018, v. 12, n. 4, p. 1, doi. 10.1371/journal.pntd.0006442
By:
- Chakraborty, Subhra;
- Harro, Clayton;
- DeNearing, Barbara;
- Brubaker, Jessica;
- Connor, Sean;
- Maier, Nicole;
- Dally, Len;
- Flores, Jorge;
- Bourgeois, A. Louis;
- Walker, Richard;
- Sack, David A.
Publication type:
Article
Validation of a Human Challenge Model Using an LT-Expressing Enterotoxigenic E. coli Strain (LSN03-016011) and Characterization of Potential Amelioration of Disease by an Investigational Oral Vaccine Candidate (VLA1701).
Published in:
Microorganisms, 2024, v. 12, n. 4, p. 727, doi. 10.3390/microorganisms12040727
By:
- Talaat, Kawsar R.;
- Porter, Chad K.;
- Chakraborty, Subhra;
- Feijoo, Brittany L.;
- Brubaker, Jessica;
- Adjoodani, Brittany M.;
- DeNearing, Barbara;
- Prouty, Michael G.;
- Poole, Steven T.;
- Bourgeois, A. Louis;
- Billingsley, Madison;
- Sack, David A.;
- Eder-Lingelbach, Susanne;
- Taucher, Christian
Publication type:
Article
Efficacy Evaluation of an Intradermally Delivered Enterotoxigenic Escherichia coli CF Antigen I Fimbrial Tip Adhesin Vaccine Coadministered with Heat-Labile Enterotoxin with LT(R192G) against Experimental Challenge with Enterotoxigenic E. coli H10407 in Healthy Adult Volunteers
Published in:
Microorganisms, 2024, v. 12, n. 2, p. 288, doi. 10.3390/microorganisms12020288
By:
- Gutiérrez, Ramiro L.;
- Porter, Chad K.;
- Harro, Clayton;
- Talaat, Kawsar;
- Riddle, Mark S.;
- DeNearing, Barbara;
- Brubaker, Jessica;
- Maciel Jr., Milton;
- Laird, Renee M.;
- Poole, Steven;
- Chakraborty, Subra;
- Maier, Nicole;
- Sack, David A.;
- Savarino, Stephen J.
Publication type:
Article
Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity.
Published in:
2019
By:
- Kumar, Pardeep;
- Kuhlmann, F Matthew;
- Chakraborty, Subhra;
- Bourgeois, A Louis;
- Foulke-Abel, Jennifer;
- Tumala, Brunda;
- Vickers, Tim J;
- Sack, David A;
- DeNearing, Barbara;
- Harro, Clayton D;
- Wright, W Shea;
- Gildersleeve, Jeffrey C;
- Ciorba, Matthew A;
- Santhanam, Srikanth;
- Porter, Chad K;
- Gutierrez, Ramiro L;
- Prouty, Michael G;
- Riddle, Mark S;
- Polino, Alexander;
- Sheikh, Alaullah
Publication type:
journal article
Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity.
Published in:
2018
By:
- Kumar, Pardeep;
- Kuhlmann, F. Matthew;
- Chakraborty, Subhra;
- Bourgeois, A. Louis;
- Foulke-Abel, Jennifer;
- Tumala, Brunda;
- Vickers, Tim J.;
- Sack, David A.;
- DeNearing, Barbara;
- Harro, Clayton D.;
- Wright, W. Shea;
- Gildersleeve, Jeffrey C.;
- Ciorba, Matthew A.;
- Santhanam, Srikanth;
- Porter, Chad K.;
- Gutierrez, Ramiro L.;
- Prouty, Michael G.;
- Riddle, Mark S.;
- Polino, Alexander;
- Sheikh, Alaullah
Publication type:
journal article
Rifaximin Fails to Prevent Campylobacteriosis in the Human Challenge Model: A Randomized, Double-Blind, Placebo-Controlled Trial.
Published in:
Clinical Infectious Diseases, 2018, v. 66, n. 9, p. 1435, doi. 10.1093/cid/cix1014
By:
- Rimmer, Joanna E;
- Harro, Clayton;
- Sack, David A;
- Talaat, Kawsar R;
- Gutierrez, Ramiro L;
- DeNearing, Barbara;
- Brubaker, Jessica;
- Laird, Renee M;
- Poly, Frédéric;
- Maue, Alexander C
Publication type:
Article
An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0149358
By:
- Porter, Chad K.;
- Riddle, Mark S.;
- Alcala, Ashley N.;
- Sack, David A.;
- Harro, Clayton;
- Chakraborty, Subhra;
- Gutierrez, Ramiro L.;
- Savarino, Stephen J.;
- Darsley, Michael;
- McKenzie, Robin;
- DeNearing, Barbara;
- Steinsland, Hans;
- Tribble, David R.;
- Bourgeois, A. Louis
Publication type:
Article
Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection.
Published in:
NPJ Vaccines, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41541-019-0131-7
By:
- Chakraborty, Subhra;
- Randall, Arlo;
- Vickers, Tim J.;
- Molina, Doug;
- Harro, Clayton D.;
- DeNearing, Barbara;
- Brubaker, Jessica;
- Sack, David A.;
- Bourgeois, A. Louis;
- Felgner, Philip L.;
- Liang, Xiaowu;
- Mani, Sachin;
- Wenzel, Heather;
- Townsend, R. Reid;
- Gilmore, Petra E.;
- Darsley, Michael J.;
- Rasko, David A.;
- Fleckenstein, James M.
Publication type:
Article
Hyperimmune Bovine Colostral Anti-CS17 Antibodies Protect Against Enterotoxigenic Escherichia coli Diarrhea in a Randomized, Doubled-Blind, Placebo-Controlled Human Infection Model.
Published in:
2019
By:
- Savarino, Stephen J;
- McKenzie, Robin;
- Tribble, David R;
- Porter, Chad K;
- O'Dowd, Aisling;
- Sincock, Stephanie A;
- Poole, Steven T;
- DeNearing, Barbara;
- Woods, Colleen M;
- Kim, Hye;
- Grahek, Shannon L;
- Brinkley, Carl;
- Crabb, Joseph H;
- Bourgeois, A Louis
Publication type:
journal article
Human Experimental Challenge With Enterotoxigenic Escherichia coli Elicits Immune Responses to Canonical and Novel Antigens Relevant to Vaccine Development.
Published in:
2018
By:
- Chakraborty, Subhra;
- Randall, Arlo;
- Vickers, Tim J;
- Molina, Doug;
- Harro, Clayton D;
- DeNearing, Barbara;
- Brubaker, Jessica;
- Sack, David A;
- Bourgeois, A Louis;
- Felgner, Philip L;
- Liang, Xiaowu;
- Mani, Sachin;
- Wenzel, Heather;
- Townsend, R Reid;
- Gilmore, Petra E;
- Darsley, Michael J;
- Rasko, David A;
- Fleckenstein, James M
Publication type:
journal article
Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial.
Published in:
2017
By:
- Savarino, Stephen J.;
- McKenzie, Robin;
- Tribble, David R.;
- Porter, Chad K.;
- O'Dowd, Aisling;
- Cantrell, Joyce A.;
- Sincock, Stephanie A.;
- Poole, Steven T.;
- DeNearing, Barbara;
- Woods, Colleen M.;
- Hye Kim;
- Grahek, Shannon L.;
- Brinkley, Carl;
- Crabb, Joseph H.;
- Bourgeois, A. Louis;
- Kim, Hye
Publication type:
journal article
Clinical endpoints in the controlled human challenge model for Shigella: A call for standardization and the development of a disease severity score.
Published in:
PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194325
By:
- Porter, Chad K.;
- Lynen, Amanda;
- Riddle, Mark S.;
- Talaat, Kawsar;
- Sack, David;
- Gutiérrez, Ramiro L.;
- McKenzie, Robin;
- DeNearing, Barbara;
- Feijoo, Brittany;
- Kaminski, Robert W.;
- Taylor, David N.;
- Kirkpatrick, Beth D.;
- Bourgeois, A. Louis
Publication type:
Article

Found: 13