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Advances and counterpoints in type 2 diabetes. What is ready for translation into real-world practice, ahead of the guidelines.
- Published in:
- BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03518-5
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- Publication type:
- Article
Increase in endogenous glucose production with SGLT2 inhibition is attenuated in individuals who underwent kidney transplantation and bilateral native nephrectomy.
- Published in:
- Diabetologia, 2020, v. 63, n. 11, p. 2423, doi. 10.1007/s00125-020-05254-w
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- Article
Decreased basal hepatic glucose uptake in impaired fasting glucose.
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- Diabetologia, 2017, v. 60, n. 7, p. 1325, doi. 10.1007/s00125-017-4252-0
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- Publication type:
- Article
Once-daily delayed-release metformin lowers plasma glucose and enhances fasting and postprandial GLP-1 and PYY: results from two randomised trials.
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- Diabetologia, 2016, v. 59, n. 8, p. 1645, doi. 10.1007/s00125-016-3992-6
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- Publication type:
- Article
Islet amyloid polypeptide response to maximal hyperglycemia and arginine is altered in impaired glucose tolerance and type 2 diabetes mellitus.
- Published in:
- Acta Diabetologica, 2017, v. 54, n. 1, p. 53, doi. 10.1007/s00592-016-0904-7
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- Publication type:
- Article
Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose.
- Published in:
- Acta Diabetologica, 2011, v. 48, n. 3, p. 209, doi. 10.1007/s00592-011-0285-x
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- Publication type:
- Article
Adipocytes in subjects with impaired fasting glucose and impaired glucose tolerance are resistant to the anti-lipolytic effect of insulin.
- Published in:
- Acta Diabetologica, 2008, v. 45, n. 3, p. 147, doi. 10.1007/s00592-008-0033-z
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- Publication type:
- Article
Pioglitazone: inexpensive; very effective at reducing HbA<sub>1c</sub>; no evidence of bladder cancer risk; plenty of evidence of cardiovascular benefit.
- Published in:
- Diabetic Medicine, 2019, v. 36, n. 9, p. 1185, doi. 10.1111/dme.14053
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- Article
Differential effect of endogenous glucagon‐like peptide‐1 on prandial glucose counterregulatory response to hypoglycaemia in humans with and without bariatric surgery.
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- Diabetes, Obesity & Metabolism, 2024, v. 26, n. 6, p. 2476, doi. 10.1111/dom.15570
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- Article
The impact of increased hepatic glucose production caused by empagliflozin on plasma glucose concentration in individuals with type 2 diabetes and nondiabetic individuals.
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- Diabetes, Obesity & Metabolism, 2024, v. 26, n. 3, p. 1033, doi. 10.1111/dom.15404
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- Article
Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes.
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- Diabetes, Obesity & Metabolism, 2023, v. 25, n. 2, p. 426, doi. 10.1111/dom.14885
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- Publication type:
- Article
Are angiotensin‐converting enzyme inhibitors/angiotensin receptor blockers associated with reduced severe acute respiratory syndrome coronavirus 2 infections and improved outcomes, and does race matter?
- Published in:
- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 12, p. 2465, doi. 10.1111/dom.14835
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- Article
Type 2 diabetes subgroups and response to glucose‐lowering therapy: Results from the EDICT and Qatar studies.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 9, p. 1810, doi. 10.1111/dom.14767
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- Publication type:
- Article
Modifying chronic kidney disease progression with the mineralocorticoid receptor antagonist finerenone in patients with type 2 diabetes.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 7, p. 1197, doi. 10.1111/dom.14696
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- Article
Efficacy of lower doses of pioglitazone after stroke or transient ischaemic attack in patients with insulin resistance.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 6, p. 1150, doi. 10.1111/dom.14687
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- Publication type:
- Article
Combination therapy with pioglitazone/exenatide/metformin reduces the prevalence of hepatic fibrosis and steatosis: The efficacy and durability of initial combination therapy for type 2 diabetes (EDICT).
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 5, p. 899, doi. 10.1111/dom.14650
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- Publication type:
- Article
Insulin secretion is a strong predictor for need of insulin therapy in patients with new‐onset diabetes and HbA1c of more than 10%: A post hoc analysis of the EDICT study.
- Published in:
- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 7, p. 1631, doi. 10.1111/dom.14383
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- Article
Combination therapy with pioglitazone/exenatide improves beta‐cell function and produces superior glycaemic control compared with basal/bolus insulin in poorly controlled type 2 diabetes: A 3‐year follow‐up of the Qatar study.
- Published in:
- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 12, p. 2287, doi. 10.1111/dom.14153
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- Publication type:
- Article
Hormone‐substrate changes with exenatide plus dapagliflozin versus each drug alone: The randomized, active‐controlled DURATION‐8 study.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 1, p. 99, doi. 10.1111/dom.13870
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- Publication type:
- Article
Pioglitazone prevents the increase in plasma ketone concentration associated with dapagliflozin in insulin‐treated T2DM patients: Results from the Qatar Study.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 3, p. 705, doi. 10.1111/dom.13546
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- Publication type:
- Article
Insulin secretion predicts the response to therapy with exenatide plus pioglitazone, but not to basal/bolus insulin in poorly controlled T2DM patients: Results from the Qatar study.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 4, p. 1075, doi. 10.1111/dom.13189
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- Publication type:
- Article
Combination therapy with GLP-1 receptor agonist and SGLT2 inhibitor.
- Published in:
- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 10, p. 1353, doi. 10.1111/dom.12982
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- Publication type:
- Article
Sodium-glucose co-transporter ( SGLT) and glucose transporter ( GLUT) expression in the kidney of type 2 diabetic subjects.
- Published in:
- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 9, p. 1322, doi. 10.1111/dom.13003
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- Publication type:
- Article
Determinants of the increase in ketone concentration during SGLT2 inhibition in NGT, IFG and T2DM patients.
- Published in:
- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 6, p. 809, doi. 10.1111/dom.12881
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- Publication type:
- Article
AMP-activated protein kinase: role in metabolism and therapeutic implications.
- Published in:
- Diabetes, Obesity & Metabolism, 2006, v. 8, n. 6, p. 591, doi. 10.1111/j.1463-1326.2005.00561.x
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- Publication type:
- Article
Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease.
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- 2013
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- Publication type:
- Journal Article
Intensive Insulin Therapy Reduces Counterregulatory Hormone Responses to Hypoglycemia in Patients with Type I Diabetes.
- Published in:
- Annals of Internal Medicine, 1985, v. 103, n. 2, p. 184, doi. 10.7326/0003-4819-103-2-184
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- Publication type:
- Article
Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp.
- Published in:
- PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208757
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- Publication type:
- Article
Increased lipid availability for three days reduces whole body glucose uptake, impairs muscle mitochondrial function and initiates opposing effects on PGC-1α promoter methylation in healthy subjects.
- Published in:
- PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188208
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- Publication type:
- Article
Reduction in hematocrit level after pioglitazone treatment is correlated with decreased plasma free testosterone level, not hemodilution, in women with polycystic ovary syndrome<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2006, v. 80, n. 2, p. 105, doi. 10.1016/j.clpt.2006.03.014
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- Article
Culture on a native bone marrow‐derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet immunogenicity.
- Published in:
- FASEB Journal, 2020, v. 34, n. 6, p. 8044, doi. 10.1096/fj.201902893R
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- Article
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.
- Published in:
- 2004
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- Publication type:
- journal article
A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.
- Published in:
- 2003
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- Publication type:
- journal article
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.
- Published in:
- 2003
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- Publication type:
- journal article
Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes.
- Published in:
- 2003
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- Publication type:
- journal article
Free fatty acids reduce splanchnic and peripheral glucose uptake in patients with type 2 diabetes.
- Published in:
- 2002
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- Publication type:
- journal article
Normalization of plasma glucose concentration by insulin therapy improves insulin-stimulated glycogen synthesis in type 2 diabetes.
- Published in:
- 2002
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- Publication type:
- journal article
Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation.
- Published in:
- 2001
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- Publication type:
- journal article
Altered hypothalamic function in response to glucose ingestion in obese humans.
- Published in:
- Diabetes, 1999, v. 48, n. 9, p. 1801, doi. 10.2337/diabetes.48.9.1801
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- Publication type:
- Article
Insulin-induced hexokinase II expression is reduced in obesity and NIDDM.
- Published in:
- 1998
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- Publication type:
- journal article
Seven days of euglycemic hyperinsulinemia induces insulin resistance for glucose metabolism but not hypertension, elevated catecholamine levels, or increased sodium retention in conscious normal rats.
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- 1997
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- Publication type:
- journal article
Roles of glucose transport and glucose phosphorylation in muscle insulin resistance of NIDDM.
- Published in:
- 1996
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- Publication type:
- journal article
Differential Responsiveness of Protein Synthesis and Degradation to Amino Acid Availability in Humans.
- Published in:
- Diabetes, 1996, v. 45, n. 4, p. 393, doi. 10.2337/diab.45.4.393
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- Publication type:
- Article
Increased glutamine:fructose-6-phosphate amidotransferase activity in skeletal muscle of patients with NIDDM.
- Published in:
- 1996
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- Publication type:
- journal article
Effects of angiotensin-converting enzyme inhibitors, Ca2+ channel antagonists, and alpha-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension.
- Published in:
- 1995
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- Publication type:
- journal article
Bedtime Insulin/Daytime Glipizide.
- Published in:
- Diabetes, 1995, v. 44, n. 2, p. 165, doi. 10.2337/diab.44.2.165
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- Publication type:
- Article
In vivo glucose metabolism in obese and type II diabetic subjects with or without hypertension.
- Published in:
- 1993
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- Publication type:
- journal article
Glucose Transport in Human Skeletal Muscle.
- Published in:
- Diabetes, 1993, v. 42, n. 1, p. 191, doi. 10.2337/diab.42.1.191
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- Publication type:
- Article
The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents.
- Published in:
- 1992
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- Publication type:
- journal article
Total Body Fat Content and Fat Topography Are Associated Differently With In Vivo Glucose Metabolism in Nonobese and Obese Nondiabetic Women.
- Published in:
- Diabetes, 1992, v. 41, n. 9, p. 1151, doi. 10.2337/diab.41.9.1151
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- Publication type:
- Article