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Pharmacological characterization of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide: a novel, clinical AMPA receptor positive allosteric modulator.
- Published in:
- 2017
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- Publication type:
- journal article
In Vitro and In Vivo Characterization of the Non-peptide NK<sub>3</sub> Receptor Antagonist SB-223412 (Talnetant): Potential Therapeutic Utility in the Treatment of Schizophrenia.
- Published in:
- Neuropsychopharmacology, 2008, v. 33, n. 8, p. 1642, doi. 10.1038/sj.npp.1301549
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- Publication type:
- Article
Neuropharmacological Profile of Novel and Selective 5-HT<sub>6</sub> Receptor Agonists: WAY-181187 and WAY-208466.
- Published in:
- Neuropsychopharmacology, 2008, v. 33, n. 7, p. 1323, doi. 10.1038/sj.npp.1301503
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- Publication type:
- Article
SB-649915-B, a Novel 5-HT<sub>1A/B</sub> Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test.
- Published in:
- Neuropsychopharmacology, 2007, v. 32, n. 10, p. 2163, doi. 10.1038/sj.npp.1301341
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- Publication type:
- Article
The Effect of Clozapine on Extracellular Dopamine Levels in the Shell Subregion of the Rat Nucleus Accumbens is Reversed Following Chronic Administration: Comparison with a...
- Published in:
- Neuropsychopharmacology, 2005, v. 30, n. 2, p. 372, doi. 10.1038/sj.npp.1300591
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- Publication type:
- Article
Vilazodone: A 5-HT<sub>1A</sub> Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective Disorders.
- Published in:
- CNS Neuroscience & Therapeutics, 2009, v. 15, n. 2, p. 107, doi. 10.1111/j.1755-5949.2008.00067.x
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- Publication type:
- Article
Pharmacological characterisation of MDI-222, a novel AMPA receptor positive allosteric modulator with an improved safety profile.
- Published in:
- 2020
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- Publication type:
- journal article
CHARACTERISATION OF AMINO ACID RELEASE FROM HIPPOCAMPAL SLICES DURING CHEMICALLY-INDUCED ISCHAEMIA.
- Published in:
- 1999
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- Publication type:
- Abstract
A Covalent Binding Mode of a Pyrazole‐Based CD38 Inhibitor.
- Published in:
- Helvetica Chimica Acta, 2023, v. 106, n. 9, p. 1, doi. 10.1002/hlca.202300080
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- Publication type:
- Article
Tackling gaps in developing life‐changing treatments for dementia.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 241, doi. 10.1016/j.trci.2019.05.001
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- Publication type:
- Article
Preclinical investigations into the antipsychotic potential of the novel histamine H<sub>3</sub> receptor antagonist GSK207040.
- Published in:
- Psychopharmacology, 2009, v. 201, n. 4, p. 483, doi. 10.1007/s00213-008-1310-9
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- Publication type:
- Article
Simultaneous blockade of 5-HT<sub>1A/B</sub> receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT<sub>1A/B</sub> receptor antagonist/5-HT transport inhibitor SB-649915-B
- Published in:
- Psychopharmacology, 2007, v. 192, n. 1, p. 121, doi. 10.1007/s00213-006-0691-x
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- Publication type:
- Article
Differential autoreceptor control of extracellular 5-HT in guinea pig and rat: species and regional differences.
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- Psychopharmacology, 2004, v. 172, n. 1, p. 87, doi. 10.1007/s00213-003-1615-7
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- Publication type:
- Article
NOVEL NLRP3 INFLAMMASOME INHIBITORS: EVALUATION IN IL-1β RELEASE AND HIGH-CONTENT ASC-SPECK CELLULAR ASSAYS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P629, doi. 10.1016/j.jalz.2017.06.713
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- Publication type:
- Article
The dementia consortium: An international partnership model to accelerate drug discovery.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P865, doi. 10.1016/j.jalz.2014.05.1728
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- Publication type:
- Article
Memantine: Assessment in novel object recognition and quantitative 2-deoxyglucose metabolism in rat
- Published in:
- 2012
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- Publication type:
- Abstract
Behavioural and cerebral metabolism assessment of TASTPM transgenic mice using a ‘touchscreen’-based cognitive task
- Published in:
- 2012
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- Publication type:
- Abstract
Examining the role of c-jun n-terminal kinase on hypothermia-induced tau phosphorylation in cortical neurons and mouse brain
- Published in:
- 2011
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- Publication type:
- Abstract
P4-387: 5-HT<sub>6</sub> receptor antagonist SB-742457 as a novel cognitive enhancing agent for Alzheimer’s disease
- Published in:
- 2006
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- Publication type:
- Abstract
P4-387: 5-HT<sub>6</sub> receptor antagonist SB-742457 as a novel cognitive enhancing agent for Alzheimer’s disease
- Published in:
- 2006
- By:
- Publication type:
- Abstract
Differential contribution of THIK-1 K<sup>+</sup> channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia.
- Published in:
- Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03042-6
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- Publication type:
- Article
The two pore potassium channel THIK‐1 regulates NLRP3 inflammasome activation.
- Published in:
- Glia, 2022, v. 70, n. 7, p. 1301, doi. 10.1002/glia.24174
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- Publication type:
- Article
The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat.
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- British Journal of Pharmacology, 2000, v. 129, n. 3, p. 541, doi. 10.1038/sj.bjp.0703105
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- Publication type:
- Article
α7 and non-α7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex.
- Published in:
- European Journal of Neuroscience, 2009, v. 29, n. 3, p. 539, doi. 10.1111/j.1460-9568.2009.06613.x
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- Publication type:
- Article
Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortex.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Clinically Precedented Protein Kinases: Rationale for Their Use in Neurodegenerative Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2020, v. 12, p. N.PAG, doi. 10.3389/fnagi.2020.00242
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- Publication type:
- Article
Fluoxetine administration modulates the cytoskeletal microtubular system in the rat hippocampus.
- Published in:
- Synapse, 2009, v. 63, n. 4, p. 359, doi. 10.1002/syn.20614
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- Publication type:
- Article
5-HT<sub>6</sub> receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex.
- Published in:
- Synapse, 2004, v. 51, n. 2, p. 158, doi. 10.1002/syn.10288
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- Publication type:
- Article
Activation of 5-HT<sub>6</sub> receptors facilitates attentional set shifting.
- Published in:
- Psychopharmacology, 2010, v. 208, n. 1, p. 13, doi. 10.1007/s00213-009-1701-6
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- Publication type:
- Article
The differing mechanisms of photo-formation of 7-cyanobenzocyclooctatetraene from 7- and 6- cyano-2,3-benzobicyclo[4.2.0]octa-2,4,7-triene.
- Published in:
- Canadian Journal of Chemistry, 2003, v. 81, n. 1, p. 37, doi. 10.1139/v02-204
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- Publication type:
- Article
NETS‐seq advances the understanding of neuronal vulnerability in AD progression facilitating the identification of novel therapeutic targets at the single cell type level.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071405
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- Publication type:
- Article